CCAAT-Enhancer-Binding Proteins
"CCAAT-Enhancer-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of proteins that were originally identified by their ability to bind the DNA sequence CCAAT. The typical CCAAT-enhancer binding protein forms dimers and consists of an activation domain, a DNA-binding basic region, and a leucine-rich dimerization domain (LEUCINE ZIPPERS). CCAAT-BINDING FACTOR is structurally distinct type of CCAAT-enhancer binding protein consisting of a trimer of three different subunits.
Descriptor ID |
D022762
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MeSH Number(s) |
D12.776.260.108.124 D12.776.660.167 D12.776.930.127.124
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Concept/Terms |
CCAAT-Enhancer-Binding Proteins- CCAAT-Enhancer-Binding Proteins
- CCAAT Enhancer Binding Proteins
- CAAT-Enhancer Binding Protein
- Binding Protein, CAAT-Enhancer
- CAAT Enhancer Binding Protein
- CCAAT-Enhancer-Binding Protein
- CCAAT Enhancer Binding Protein
- C-EBP Protein
- C EBP Protein
- C-EBP Nuclear Protein
- C EBP Nuclear Protein
- Nuclear Protein, C-EBP
- CAAT-Enhancer-Binding Proteins
- CAAT Enhancer Binding Proteins
- C-EBP Proteins
- C EBP Proteins
- CCAAT Sequence-Specific DNA-Binding Proteins
- CCAAT Sequence Specific DNA Binding Proteins
- Nuclear Protein C-EBP
- C-EBP, Nuclear Protein
- Nuclear Protein C EBP
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Below are MeSH descriptors whose meaning is more general than "CCAAT-Enhancer-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "CCAAT-Enhancer-Binding Proteins".
This graph shows the total number of publications written about "CCAAT-Enhancer-Binding Proteins" by people in this website by year, and whether "CCAAT-Enhancer-Binding Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 | 1997 | 0 | 1 | 1 | 1999 | 2 | 0 | 2 | 2000 | 1 | 0 | 1 | 2002 | 1 | 0 | 1 | 2003 | 1 | 1 | 2 | 2004 | 3 | 2 | 5 | 2005 | 2 | 4 | 6 | 2008 | 0 | 1 | 1 | 2009 | 0 | 1 | 1 | 2010 | 0 | 1 | 1 | 2011 | 0 | 1 | 1 | 2013 | 1 | 0 | 1 | 2016 | 0 | 2 | 2 | 2020 | 0 | 1 | 1 | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "CCAAT-Enhancer-Binding Proteins" by people in Profiles.
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Higa KC, Goodspeed A, Chavez JS, De Dominici M, Danis E, Zaberezhnyy V, Rabe JL, Tenen DG, Pietras EM, DeGregori J. Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors. J Exp Med. 2021 06 07; 218(6).
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Masuda M, Yamamoto H, Takei Y, Nakahashi O, Adachi Y, Ohnishi K, Ohminami H, Yamanaka-Okumura H, Sakaue H, Miyazaki M, Takeda E, Taketani Y. All-trans retinoic acid reduces the transcriptional regulation of intestinal sodium-dependent phosphate co-transporter gene (Npt2b). Biochem J. 2020 02 28; 477(4):817-831.
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Vanoni S, Tsai YT, Waddell A, Waggoner L, Klarquist J, Divanovic S, Hoebe K, Steinbrecher KA, Hogan SP. Myeloid-derived NF-?B negative regulation of PU.1 and c/EBP-?-driven pro-inflammatory cytokine production restrains LPS-induced shock. Innate Immun. 2017 02; 23(2):175-187.
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Stein SJ, Mack EA, Rome KS, Pajcini KV, Ohtani T, Xu L, Li Y, Meijerink JP, Faryabi RB, Pear WS. Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL. PLoS One. 2016; 11(5):e0155408.
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Huang H, Li Y, Liu B. Transcriptional regulation of mast cell and basophil lineage commitment. Semin Immunopathol. 2016 09; 38(5):539-48.
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Lee B, Qiao L, Lu M, Yoo HS, Cheung W, Mak R, Schaack J, Feng GS, Chi NW, Olefsky JM, Shao J. C/EBPa regulates macrophage activation and systemic metabolism. Am J Physiol Endocrinol Metab. 2014 May 15; 306(10):E1144-54.
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Di Ruscio A, Ebralidze AK, Benoukraf T, Amabile G, Goff LA, Terragni J, Figueroa ME, De Figueiredo Pontes LL, Alberich-Jorda M, Zhang P, Wu M, D'Al? F, Melnick A, Leone G, Ebralidze KK, Pradhan S, Rinn JL, Tenen DG. DNMT1-interacting RNAs block gene-specific DNA methylation. Nature. 2013 Nov 21; 503(7476):371-6.
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Murray DR, Mummidi S, Valente AJ, Yoshida T, Somanna NK, Delafontaine P, Dinarello CA, Chandrasekar B. ?2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial hypertrophy in vivo. J Mol Cell Cardiol. 2012 Jan; 52(1):206-18.
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Musunuru K, Strong A, Frank-Kamenetsky M, Lee NE, Ahfeldt T, Sachs KV, Li X, Li H, Kuperwasser N, Ruda VM, Pirruccello JP, Muchmore B, Prokunina-Olsson L, Hall JL, Schadt EE, Morales CR, Lund-Katz S, Phillips MC, Wong J, Cantley W, Racie T, Ejebe KG, Orho-Melander M, Melander O, Koteliansky V, Fitzgerald K, Krauss RM, Cowan CA, Kathiresan S, Rader DJ. From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus. Nature. 2010 Aug 05; 466(7307):714-9.
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Rahman SM, Qadri I, Janssen RC, Friedman JE. Fenofibrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis. J Lipid Res. 2009 Nov; 50(11):2193-202.
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