gamma-Aminobutyric Acid
"gamma-Aminobutyric Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The most common inhibitory neurotransmitter in the central nervous system.
| Descriptor ID |
D005680
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| MeSH Number(s) |
D02.241.081.114.500.350 D12.125.190.350
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| Concept/Terms |
gamma-Aminobutyric Acid- gamma-Aminobutyric Acid
- gamma Aminobutyric Acid
- GABA
- Aminalon
- Aminalone
- 4-Aminobutanoic Acid
- 4 Aminobutanoic Acid
- 4-Aminobutyric Acid
- 4 Aminobutyric Acid
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Below are MeSH descriptors whose meaning is more general than "gamma-Aminobutyric Acid".
Below are MeSH descriptors whose meaning is more specific than "gamma-Aminobutyric Acid".
This graph shows the total number of publications written about "gamma-Aminobutyric Acid" by people in this website by year, and whether "gamma-Aminobutyric Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 0 | 3 | 3 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 2 | 2 | | 2002 | 5 | 2 | 7 | | 2003 | 2 | 3 | 5 | | 2004 | 1 | 1 | 2 | | 2005 | 2 | 1 | 3 | | 2006 | 2 | 1 | 3 | | 2007 | 1 | 1 | 2 | | 2008 | 5 | 3 | 8 | | 2009 | 4 | 5 | 9 | | 2010 | 2 | 3 | 5 | | 2011 | 4 | 5 | 9 | | 2012 | 2 | 3 | 5 | | 2013 | 2 | 3 | 5 | | 2014 | 7 | 4 | 11 | | 2015 | 5 | 0 | 5 | | 2016 | 2 | 4 | 6 | | 2017 | 6 | 6 | 12 | | 2018 | 1 | 2 | 3 | | 2019 | 6 | 1 | 7 | | 2020 | 2 | 4 | 6 | | 2021 | 3 | 4 | 7 | | 2022 | 2 | 4 | 6 | | 2023 | 0 | 6 | 6 | | 2024 | 1 | 1 | 2 | | 2025 | 5 | 1 | 6 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "gamma-Aminobutyric Acid" by people in Profiles.
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Strom NI, Verhulst B, Bacanu SA, Cheesman R, Purves KL, Gedik H, Mitchell BL, Kwong AS, Faucon AB, Singh K, Medland S, Colodro-Conde L, Krebs K, Hoffmann P, Herms S, Gehlen J, Ripke S, Awasthi S, Palviainen T, Tasanko EM, Peterson RE, Adkins DE, Shabalin AA, Adams MJ, Iveson MH, Campbell A, Thomas LF, Winsvold BS, Drange OK, Børte S, Ter Kuile AR, Naamanka J, Nguyen TH, Meier SM, Corfield EC, Hannigan L, Levey DF, Czamara D, Weber H, Choi KW, Pistis G, Couvy-Duchesne B, Van der Auwera S, Teumer A, Karlsson R, Garcia-Argibay M, Lee D, Wang R, Bjerkeset O, Stordal E, Bäckman J, Salum GA, Zai CC, Kennedy JL, Zai G, Tiwari AK, Heilmann-Heimbach S, Schmidt B, Kaprio J, Kennedy MM, Boden J, Havdahl A, Middeldorp CM, Lopes FL, Akula N, McMahon FJ, Binder EB, Fehm L, Ströhle A, Castelao E, Tiemeier H, Stein DJ, Whiteman D, Olsen C, Fuller Z, Wang X, Wray NR, Byrne EM, Lewis G, Timpson NJ, Davis LK, Hickie IB, Gillespie NA, Milani L, Schumacher J, Woldbye DP, Forstner AJ, Nöthen MM, Hovatta I, Horwood J, Copeland WE, Maes HH, McIntosh AM, Andreassen OA, Zwart JA, Mors O, Børglum AD, Mortensen PB, Ask H, Reichborn-Kjennerud T, Najman JM, Stein MB, Gelernter J, Milaneschi Y, Penninx BW, Boomsma DI, Maron E, Erhardt-Lehmann A, Rück C, Kircher TT, Melzig CA, Alpers GW, Arolt V, Domschke K, Smoller JW, Preisig M, Martin NG, Lupton MK, Luik AI, Reif A, Grabe HJ, Larsson H, Magnusson PK, Oldehinkel AJ, Hartman CA, Breen G, Docherty AR, Coon H, Conrad R, Lehto K, Deckert J, Eley TC, Mattheisen M, Hettema JM. Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling. Nat Genet. 2026 Feb; 58(2):275-288.
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Jaime J, DeFazio RA, Moenter SM. Response of gonadotropin-releasing hormone neurons from female mice to dynamic-clamp-simulated GABAergic conductances across development and after prenatal androgenization. J Neuroendocrinol. 2026 Feb; 38(2):e70144.
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Lee HY, Lee JM, Lee HL, Park J, An H, Park EK, Hwang SY, Yoon SL, Hwang GY, Kim KN, Nam MH, Lee SE, Kang H, Won J, Jang BK, Lee EH, Choi S, Park MG, Kim SW, Park KD, Lee S, Lee CJ, Ha Y. Astrocytic monoamine oxidase B (MAOB)-gamma-aminobutyric acid (GABA) axis as a molecular brake on repair following spinal cord injury. Signal Transduct Target Ther. 2025 09 11; 10(1):295.
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Savchuk S, Gentry KM, Wang W, Carleton E, Biagi-Junior CAO, Luthria K, Yalçin B, Ni L, Farnsworth HC, Davis RA, Drexler R, Melms JC, Liu Y, Acosta-Alvarez L, Hartmann GG, Pavarino EC, LaBelle J, Woo PJ, Toland AM, Qu F, Kim YS, Filbin MG, Krasnow MA, Ligon KL, Izar B, Sage J, Sabatini BL, Monje M, Venkatesh HS. Neuronal activity-dependent mechanisms of small cell lung cancer pathogenesis. Nature. 2025 10; 646(8087):1232-1242.
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Coutens B, Bouchet CA, Patti LC, McPherson KB, Boston BS, Jewett DC, Ingram SL. Corticosterone stimulates synthesis of 2-arachidonoylglycerol via putative membrane-bound glucocorticoid receptors and inhibits GABA release via CB1 cannabinoid receptors in the ventrolateral periaqueductal gray. Mol Pharmacol. 2025 08; 107(8):100058.
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Ly A, Karnosky R, Prévost ED, Hotchkiss H, Pelletier JM, Spencer RL, Ford CP, Root DH. VGluT3 BNST neurons transmit GABA and restrict sucrose consumption. Mol Metab. 2025 08; 98:102178.
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Wang K, Smolker HR, Brown MS, Snyder HR, Cheng Y, Hankin BL, Banich MT. Intrinsic Functional Connectivity Associated with ?-Aminobutyric Acid and Glutamate/Glutamine in the Lateral Prefrontal Cortex and Internalizing Psychopathology in Adolescents. Neurosci Bull. 2025 Sep; 41(9):1553-1569.
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Hughes LE, Adams NE, Rouse MA, Naessens M, Shaw A, Murley AG, Cope TE, Holland N, Nesbitt D, Street D, Whiteside DJ, Rowe JB. GABAergic modulation of beta power enhances motor adaptation in frontotemporal lobar degeneration. Alzheimers Dement. 2025 05; 21(5):e14531.
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Welle TM, Smith KR. Release your inhibitions: The cell biology of GABAergic postsynaptic plasticity. Curr Opin Neurobiol. 2025 Feb; 90:102952.
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Prévost ED, Phillips A, Lauridsen K, Enserro G, Rubinstein B, Alas D, McGovern DJ, Ly A, Hotchkiss H, Banks M, McNulty C, Kim YS, Fenno LE, Ramakrishnan C, Deisseroth K, Root DH. Monosynaptic Inputs to Ventral Tegmental Area Glutamate and GABA Co-transmitting Neurons. J Neurosci. 2024 11 13; 44(46).
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