 Hydrazones
"Hydrazones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds of the general formula R:N.NR2, as resulting from the action of hydrazines with aldehydes or ketones. (Grant & Hackh's Chemical Dictionary, 5th ed)
| Descriptor ID |
D006835
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| MeSH Number(s) |
D02.442.288
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hydrazones".
Below are MeSH descriptors whose meaning is more specific than "Hydrazones".
This graph shows the total number of publications written about "Hydrazones" by people in this website by year, and whether "Hydrazones" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2012 | 0 | 2 | 2 | | 2013 | 0 | 2 | 2 | | 2014 | 3 | 0 | 3 | | 2015 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 | | 2019 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Hydrazones" by people in Profiles.
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Borelli AN, Young MW, Kirkpatrick BE, Jaeschke MW, Mellett S, Porter S, Blatchley MR, Rao VV, Sridhar BV, Anseth KS. Stress Relaxation and Composition of Hydrazone-Crosslinked Hybrid Biopolymer-Synthetic Hydrogels Determine Spreading and Secretory Properties of MSCs. Adv Healthc Mater. 2022 07; 11(14):e2200393.
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Muir VG, Qazi TH, Weintraub S, Torres Maldonado BO, Arratia PE, Burdick JA. Sticking Together: Injectable Granular Hydrogels with Increased Functionality via Dynamic Covalent Inter-Particle Crosslinking. Small. 2022 09; 18(36):e2201115.
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Richardson BM, Walker CJ, Maples MM, Randolph MA, Bryant SJ, Anseth KS. Mechanobiological Interactions between Dynamic Compressive Loading and Viscoelasticity on Chondrocytes in Hydrazone Covalent Adaptable Networks for Cartilage Tissue Engineering. Adv Healthc Mater. 2021 05; 10(9):e2002030.
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Richardson BM, Walker CJ, Macdougall LJ, Hoye JW, Randolph MA, Bryant SJ, Anseth KS. Viscoelasticity of hydrazone crosslinked poly(ethylene glycol) hydrogels directs chondrocyte morphology during mechanical deformation. Biomater Sci. 2020 Jul 21; 8(14):3804-3811.
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Zhang C, Wang R, Liu Z, Bunker E, Lee S, Giuntini M, Chapnick D, Liu X. The plant triterpenoid celastrol blocks PINK1-dependent mitophagy by disrupting PINK1's association with the mitochondrial protein TOM20. J Biol Chem. 2019 05 03; 294(18):7472-7487.
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Richardson BM, Wilcox DG, Randolph MA, Anseth KS. Hydrazone covalent adaptable networks modulate extracellular matrix deposition for cartilage tissue engineering. Acta Biomater. 2019 01 01; 83:71-82.
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Boudoures AL, Saben J, Drury A, Scheaffer S, Modi Z, Zhang W, Moley KH. Obesity-exposed oocytes accumulate and transmit damaged mitochondria due to an inability to activate mitophagy. Dev Biol. 2017 06 01; 426(1):126-138.
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Ostroff LE, Botsford B, Gindina S, Cowansage KK, LeDoux JE, Klann E, Hoeffer C. Accumulation of Polyribosomes in Dendritic Spine Heads, But Not Bases and Necks, during Memory Consolidation Depends on Cap-Dependent Translation Initiation. J Neurosci. 2017 02 15; 37(7):1862-1872.
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Van Rechem C, Black JC, Boukhali M, Aryee MJ, Gr?slund S, Haas W, Benes CH, Whetstine JR. Lysine demethylase KDM4A associates with translation machinery and regulates protein synthesis. Cancer Discov. 2015 Mar; 5(3):255-63.
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McKinnon DD, Domaille DW, Brown TE, Kyburz KA, Kiyotake E, Cha JN, Anseth KS. Measuring cellular forces using bis-aliphatic hydrazone crosslinked stress-relaxing hydrogels. Soft Matter. 2014 Dec 14; 10(46):9230-6.
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