 Fluoxetine
"Fluoxetine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than traditional antidepressants.
| Descriptor ID |
D005473
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| MeSH Number(s) |
D02.092.831.280
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| Concept/Terms |
Fluoxetine- Fluoxetine
- Fluoxetin
- N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine
|
Below are MeSH descriptors whose meaning is more general than "Fluoxetine".
Below are MeSH descriptors whose meaning is more specific than "Fluoxetine".
This graph shows the total number of publications written about "Fluoxetine" by people in this website by year, and whether "Fluoxetine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 2 | 1 | 3 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 2 | 1 | 3 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2013 | 1 | 1 | 2 | | 2015 | 2 | 1 | 3 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 | | 2021 | 1 | 0 | 1 | | 2023 | 2 | 0 | 2 | | 2024 | 2 | 0 | 2 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fluoxetine" by people in Profiles.
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Payet JM, Baratta MV, Christianson JP, Lowry CA, Hale MW. Modulation of dorsal raphe nucleus connectivity and serotonergic signalling to the insular cortex in the prosocial effects of chronic fluoxetine. Neuropharmacology. 2025 Jul 01; 272:110406.
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Mohamed NMM, Meredith FL, Rennie KJ. Inhibition of Ionic Currents by Fluoxetine in Vestibular Calyces in Different Epithelial Loci. Int J Mol Sci. 2024 Aug 13; 25(16).
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Ogelman R, Gomez Wulschner LE, Hoelscher VM, Hwang IW, Chang VN, Oh WC. Serotonin modulates excitatory synapse maturation in the developing prefrontal cortex. Nat Commun. 2024 Feb 16; 15(1):1368.
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Payet JM, Stevens L, Russo AM, Jaehne EJ, van den Buuse M, Kent S, Lowry CA, Baratta MV, Hale MW. The Role of Dorsal Raphe Nucleus Serotonergic Systems in Emotional Learning and Memory in Male BALB/c Mice. Neuroscience. 2023 Dec 01; 534:1-15.
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Haque TT, Taruselli MT, Kee SA, Dailey JM, Pondicherry N, Gajewski-Kurdziel PA, Zellner MP, Stephenson DJ, MacKnight HP, Straus DB, Kankaria R, Jackson KG, Chumanevich AP, Fukuoka Y, Schwartz LB, Blakely RD, Oskeritzian CA, Chalfant CE, Martin RK, Ryan JJ. Fluoxetine restrains allergic inflammation by targeting an Fc?RI-ATP positive feedback loop in mast cells. Sci Signal. 2023 09 12; 16(802):eabc9089.
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Payet JM, Wilson KE, Russo AM, Angiolino A, Kavanagh-Ryan W, Kent S, Lowry CA, Hale MW. Involvement of dorsal raphe nucleus serotonergic systems in social approach-avoidance behaviour and in the response to fluoxetine treatment in peri-adolescent female BALB/c mice. Behav Brain Res. 2021 06 25; 408:113268.
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Ramsteijn AS, Ja?arevic E, Houwing DJ, Bale TL, Olivier JD. Antidepressant treatment with fluoxetine during pregnancy and lactation modulates the gut microbiome and metabolome in a rat model relevant to depression. Gut Microbes. 2020 07 03; 11(4):735-753.
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Orrico-Sanchez A, Chausset-Boissarie L, Alves de Sousa R, Coutens B, Rezai Amin S, Vialou V, Louis F, Hessani A, Dansette PM, Zornoza T, Gruszczynski C, Giros B, Guiard BP, Acher F, Pietrancosta N, Gautron S. Antidepressant efficacy of a selective organic cation transporter blocker in a mouse model of depression. Mol Psychiatry. 2020 06; 25(6):1245-1259.
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Hinckley JD, Riggs P. Integrated Treatment of Adolescents with Co-occurring Depression and Substance Use Disorder. Child Adolesc Psychiatr Clin N Am. 2019 07; 28(3):461-472.
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Schlansky K, Facer B, Tanguturi YC, Cundiff AW, Fuchs DC. Pediatric Acute-Onset Neuropsychiatric Syndrome and Catatonia: A Case Report. Psychosomatics. 2020 Jan - Feb; 61(1):86-91.
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