 Pyramidal Cells
"Pyramidal Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Projection neurons in the CEREBRAL CORTEX and the HIPPOCAMPUS. Pyramidal cells have a pyramid-shaped soma with the apex and an apical dendrite pointed toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their cortical region.
| Descriptor ID |
D017966
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| MeSH Number(s) |
A08.675.790 A11.671.790
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| Concept/Terms |
Pyramidal Cells- Pyramidal Cells
- Cell, Pyramidal
- Cells, Pyramidal
- Pyramidal Cell
- Pyramidal Neurons
- Neuron, Pyramidal
- Neurons, Pyramidal
- Pyramidal Neuron
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Below are MeSH descriptors whose meaning is more general than "Pyramidal Cells".
Below are MeSH descriptors whose meaning is more specific than "Pyramidal Cells".
This graph shows the total number of publications written about "Pyramidal Cells" by people in this website by year, and whether "Pyramidal Cells" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1998 | 1 | 1 | 2 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2003 | 1 | 4 | 5 | | 2004 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2007 | 1 | 1 | 2 | | 2008 | 3 | 0 | 3 | | 2009 | 2 | 2 | 4 | | 2010 | 0 | 2 | 2 | | 2011 | 2 | 2 | 4 | | 2012 | 1 | 1 | 2 | | 2013 | 2 | 0 | 2 | | 2014 | 3 | 0 | 3 | | 2015 | 1 | 3 | 4 | | 2016 | 0 | 2 | 2 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 1 | 2 | | 2020 | 3 | 1 | 4 | | 2022 | 0 | 2 | 2 | | 2024 | 0 | 4 | 4 | | 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Pyramidal Cells" by people in Profiles.
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Kushner JK, Hoffman PB, Brzezinski CR, Svalina MN, O'Neill BR, Hankinson TC, Wilkinson CC, Handler MH, Baca SM, Huntsman MM, Alexander AL. Characterizing the Diversity of Layer 2/3 Human Neocortical Neurons in Pediatric Epilepsy. eNeuro. 2025 May; 12(5).
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Abreo TJ, Thompson EC, Madabushi A, Park KL, Soh H, Varghese N, Vanoye CG, Springer K, Johnson J, Sims S, Ji Z, Chavez AG, Jankovic MJ, Habte B, Zuberi AR, Lutz CM, Wang Z, Krishnan V, Dudler L, Einsele-Scholz S, Noebels JL, George AL, Maheshwari A, Tzingounis A, Cooper EC. Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy. Elife. 2025 Jan 06; 13.
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Sim?es de Oliveira L, O'Leary HE, Nawaz S, Loureiro R, Davenport EC, Baxter P, Louros SR, Dando O, Perkins E, Peltier J, Trost M, Osterweil EK, Hardingham GE, Cousin MA, Chattarji S, Booker SA, Benke TA, Wyllie DJA, Kind PC. Enhanced hippocampal LTP but normal NMDA receptor and AMPA receptor function in a rat model of CDKL5 deficiency disorder. Mol Autism. 2024 06 14; 15(1):28.
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Thomas CI, Ryan MA, McNabb MC, Kamasawa N, Scholl B. Astrocyte coverage of excitatory synapses correlates to measures of synapse structure and function in ferret primary visual cortex. Glia. 2024 Oct; 72(10):1785-1800.
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Koek LA, Scholl B. Mirrored might: A vision for inhibition. Neuron. 2024 Mar 20; 112(6):868-869.
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Ogelman R, Gomez Wulschner LE, Hoelscher VM, Hwang IW, Chang VN, Oh WC. Serotonin modulates excitatory synapse maturation in the developing prefrontal cortex. Nat Commun. 2024 Feb 16; 15(1):1368.
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Otor Y, Achvat S, Cermak N, Benisty H, Abboud M, Barak O, Schiller Y, Poleg-Polsky A, Schiller J. Dynamic compartmental computations in tuft dendrites of layer 5 neurons during motor behavior. Science. 2022 04 15; 376(6590):267-275.
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Kim J, Kim S, Kim H, Hwang IW, Bae S, Karki S, Kim D, Ogelman R, Bang G, Kim JY, Kajander T, Um JW, Oh WC, Ko J. MDGA1 negatively regulates amyloid precursor protein-mediated synapse inhibition in the hippocampus. Proc Natl Acad Sci U S A. 2022 01 25; 119(4).
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Scholl B, Thomas CI, Ryan MA, Kamasawa N, Fitzpatrick D. Cortical response selectivity derives from strength in numbers of synapses. Nature. 2021 02; 590(7844):111-114.
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Raol YH, Joksimovic SM, Sampath D, Matter BA, Lam PM, Kompella UB, Todorovic SM, Gonz?lez MI. The role of KCC2 in hyperexcitability of the neonatal brain. Neurosci Lett. 2020 11 01; 738:135324.
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