 Ribosomal Protein S6
"Ribosomal Protein S6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ribosomal protein that may play a role in controlling cell growth and proliferation. It is a major substrate of RIBOSOMAL PROTEIN S6 KINASES and plays a role in regulating the translation (TRANSLATION, GENETIC) of RNAs that contain an RNA 5' TERMINAL OLIGOPYRIMIDINE SEQUENCE.
| Descriptor ID |
D038601
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| MeSH Number(s) |
D12.776.835.931
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ribosomal Protein S6".
Below are MeSH descriptors whose meaning is more specific than "Ribosomal Protein S6".
This graph shows the total number of publications written about "Ribosomal Protein S6" by people in this website by year, and whether "Ribosomal Protein S6" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 | | 2010 | 0 | 2 | 2 | | 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ribosomal Protein S6" by people in Profiles.
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Valjent E, Bertran-Gonzalez J, Bowling H, Lopez S, Santini E, Matamales M, Bonito-Oliva A, Herv? D, Hoeffer C, Klann E, Girault JA, Fisone G. Haloperidol regulates the state of phosphorylation of ribosomal protein S6 via activation of PKA and phosphorylation of DARPP-32. Neuropsychopharmacology. 2011 Nov; 36(12):2561-70.
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Lyubchenko T, Woodward H, Veo KD, Burns N, Nijmeh H, Liubchenko GA, Stenmark KR, Gerasimovskaya EV. P2Y1 and P2Y13 purinergic receptors mediate Ca2+ signaling and proliferative responses in pulmonary artery vasa vasorum endothelial cells. Am J Physiol Cell Physiol. 2011 Feb; 300(2):C266-75.
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Belibi F, Ravichandran K, Zafar I, He Z, Edelstein CL. mTORC1/2 and rapamycin in female Han:SPRD rats with polycystic kidney disease. Am J Physiol Renal Physiol. 2011 Jan; 300(1):F236-44.
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Cloughesy TF, Yoshimoto K, Nghiemphu P, Brown K, Dang J, Zhu S, Hsueh T, Chen Y, Wang W, Youngkin D, Liau L, Martin N, Becker D, Bergsneider M, Lai A, Green R, Oglesby T, Koleto M, Trent J, Horvath S, Mischel PS, Mellinghoff IK, Sawyers CL. Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma. PLoS Med. 2008 Jan 22; 5(1):e8.
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Mourani PM, Garl PJ, Wenzlau JM, Carpenter TC, Stenmark KR, Weiser-Evans MC. Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN. Circulation. 2004 Mar 16; 109(10):1299-306.
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Krebs EG, Ahn NG, Campbell JS, Graves LM, Seger R, Weiel JE. Regulation of protein serine/threonine kinases by tyrosine kinases. Adv Second Messenger Phosphoprotein Res. 1993; 28:227-36.
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Weiel JE, Ahn NG, Seger R, Krebs EG. Communication between protein tyrosine and protein serine/threonine phosphorylation. Adv Second Messenger Phosphoprotein Res. 1990; 24:182-95.
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Nemenoff RA, Price DJ, Mendelsohn MJ, Carter EA, Avruch J. An S6 kinase activated during liver regeneration is related to the insulin-stimulated S6 kinase in H4 hepatoma cells. J Biol Chem. 1988 Dec 25; 263(36):19455-60.
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Blackshear PJ, Stumpo DJ, Huang JK, Nemenoff RA, Spach DH. Protein kinase C-dependent and -independent pathways of proto-oncogene induction in human astrocytoma cells. J Biol Chem. 1987 Jun 05; 262(16):7774-81.
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Blackshear PJ, Nemenoff RA, Hovis JG, Halsey DL, Stumpo DJ, Huang JK. Insulin action in normal and protein kinase C-deficient rat hepatoma cells. Effects on protein phosphorylation, protein kinase activities, and ornithine decarboxylase activities and messenger ribonucleic acid levels. Mol Endocrinol. 1987 Jan; 1(1):44-52.
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