Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

John Tentler

Concepts (387)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Pyrimidines
8
2020
458
1.500
Why?
Xenograft Model Antitumor Assays
21
2020
808
1.330
Why?
Triple Negative Breast Neoplasms
5
2020
193
1.310
Why?
Protein Kinase Inhibitors
15
2020
886
1.300
Why?
Antineoplastic Agents
18
2019
2044
1.220
Why?
Colorectal Neoplasms
11
2018
748
1.030
Why?
Proto-Oncogene Proteins
10
2018
634
0.960
Why?
Azepines
4
2020
88
0.880
Why?
Piperazines
4
2020
339
0.860
Why?
Quinoxalines
2
2020
64
0.830
Why?
Pyrazoles
4
2018
403
0.810
Why?
Melanoma
10
2018
730
0.790
Why?
Gene Expression Regulation, Neoplastic
9
2020
1327
0.770
Why?
Mice, Nude
16
2020
680
0.690
Why?
Cell Proliferation
21
2020
2378
0.650
Why?
beta Catenin
2
2020
224
0.640
Why?
Enoyl-CoA Hydratase
1
2018
8
0.620
Why?
Lymphocytes, Tumor-Infiltrating
1
2020
204
0.600
Why?
DNA-Binding Proteins
8
2015
1441
0.560
Why?
Cell Line, Tumor
24
2020
3184
0.550
Why?
Tumor Microenvironment
1
2020
627
0.520
Why?
Benzimidazoles
4
2013
162
0.520
Why?
Mutation
11
2018
3705
0.500
Why?
Tumor Suppressor Proteins
2
2015
311
0.480
Why?
Cardiomyopathy, Dilated
1
2018
381
0.480
Why?
Tumor Suppressor Protein p53
4
2016
503
0.470
Why?
ras Proteins
3
2013
143
0.440
Why?
Genomics
1
2018
716
0.430
Why?
Pyrazines
5
2013
87
0.420
Why?
Proto-Oncogene Proteins B-raf
4
2018
210
0.390
Why?
Apoptosis
13
2020
2489
0.380
Why?
Oncogene Proteins, Fusion
3
2018
201
0.370
Why?
Drug Design
1
2012
158
0.360
Why?
Biomarkers, Tumor
3
2017
1161
0.350
Why?
Prolactin
7
2004
97
0.340
Why?
Mice
21
2020
16982
0.340
Why?
Mitogen-Activated Protein Kinase Kinases
1
2010
131
0.340
Why?
Nuclear Proteins
1
2015
660
0.340
Why?
Histone Deacetylase Inhibitors
3
2022
209
0.330
Why?
Drug Resistance, Neoplasm
8
2020
752
0.330
Why?
Aurora Kinase A
4
2020
53
0.320
Why?
Animals
44
2020
35404
0.290
Why?
Cell Transformation, Neoplastic
4
2013
319
0.280
Why?
Neoplasms
4
2022
2454
0.280
Why?
Imidazoles
4
2013
235
0.280
Why?
Pituitary Gland
7
2003
148
0.270
Why?
Hydroxamic Acids
3
2011
88
0.250
Why?
Ethanol
11
1997
591
0.250
Why?
Gene Expression Profiling
6
2018
1686
0.250
Why?
Exome
2
2017
216
0.240
Why?
Ubiquitin-Activating Enzymes
2
2016
16
0.240
Why?
Antineoplastic Combined Chemotherapy Protocols
6
2020
1560
0.230
Why?
Breast Neoplasms
3
2012
2104
0.230
Why?
Transcription Factors
4
2011
1645
0.230
Why?
Pyrimidinones
2
2015
102
0.230
Why?
Pyridones
2
2015
158
0.210
Why?
Receptor, IGF Type 1
3
2013
64
0.210
Why?
Cell Cycle Proteins
3
2018
583
0.200
Why?
Humans
44
2022
129687
0.190
Why?
Hypothalamus
12
1997
148
0.190
Why?
Immunoblotting
5
2015
306
0.190
Why?
Drug Synergism
4
2018
370
0.180
Why?
Tumor Cells, Cultured
3
2020
930
0.180
Why?
c-Mer Tyrosine Kinase
2
2018
44
0.180
Why?
G2 Phase Cell Cycle Checkpoints
3
2018
45
0.170
Why?
Female
27
2020
68751
0.170
Why?
Transcription, Genetic
4
2013
1416
0.170
Why?
Benzoxazoles
1
2020
20
0.170
Why?
Breast
3
2018
140
0.170
Why?
Boronic Acids
2
2011
37
0.170
Why?
Wnt Signaling Pathway
2
2019
170
0.160
Why?
Signal Transduction
10
2018
4935
0.160
Why?
Growth Hormone
3
1997
100
0.160
Why?
eIF-2 Kinase
1
2019
30
0.160
Why?
Sequence Analysis, RNA
2
2018
426
0.160
Why?
Epithelial Cells
4
2011
1063
0.160
Why?
Proto-Oncogene Proteins p21(ras)
4
2016
259
0.150
Why?
Cell Cycle
7
2018
583
0.150
Why?
Breast Neoplasms, Male
1
2018
28
0.150
Why?
Linkage Disequilibrium
1
2018
257
0.150
Why?
MAP Kinase Kinase Kinases
2
2015
70
0.140
Why?
Cytochrome P-450 Enzyme System
1
2018
151
0.140
Why?
Septins
1
2018
43
0.140
Why?
Mice, Inbred BALB C
1
2020
1248
0.140
Why?
Drug Therapy, Combination
1
2020
1042
0.140
Why?
Genetics, Population
1
2018
200
0.140
Why?
Cytoskeleton
1
2018
184
0.140
Why?
Neurofibromin 1
1
2017
25
0.140
Why?
Somatostatin
1
1997
56
0.140
Why?
Gonadotropin-Releasing Hormone
8
1993
204
0.140
Why?
Armadillo Domain Proteins
1
2017
6
0.140
Why?
Testis
2
1997
144
0.130
Why?
Proto-Oncogene Proteins c-kit
1
2017
63
0.130
Why?
RNA Splicing Factors
1
2017
52
0.130
Why?
Proto-Oncogene Proteins c-ret
1
2017
30
0.130
Why?
Sexual Maturation
1
1997
52
0.130
Why?
Inhibitory Concentration 50
2
2016
86
0.130
Why?
Cyclopentanes
1
2016
19
0.130
Why?
Adenine
1
2018
257
0.130
Why?
Gene Regulatory Networks
1
2018
280
0.130
Why?
Cyclic AMP Response Element-Binding Protein
1
1997
141
0.130
Why?
Mucous Membrane
1
2017
125
0.130
Why?
Cyclic AMP-Dependent Protein Kinases
1
1997
133
0.130
Why?
Genes, erbB-1
1
2016
17
0.130
Why?
RNA, Messenger
10
2003
2702
0.130
Why?
Oligonucleotide Array Sequence Analysis
3
2015
756
0.120
Why?
Education, Graduate
1
2015
34
0.120
Why?
Drug Discovery
1
2016
131
0.120
Why?
HT29 Cells
2
2018
36
0.120
Why?
Peptides, Cyclic
1
1997
256
0.120
Why?
Skin Neoplasms
2
2013
829
0.120
Why?
Tumor Protein p73
1
2015
14
0.120
Why?
Proteasome Endopeptidase Complex
2
2013
149
0.120
Why?
Neoplasm Invasiveness
3
2018
483
0.120
Why?
Phosphoproteins
1
2017
333
0.120
Why?
Mitogen-Activated Protein Kinases
2
2014
312
0.110
Why?
Computational Biology
2
2016
594
0.110
Why?
Luteinizing Hormone
8
1993
178
0.110
Why?
Cluster Analysis
2
2012
482
0.110
Why?
Testosterone
2
1997
372
0.110
Why?
Case-Control Studies
2
2018
3381
0.110
Why?
Phosphorylation
5
2019
1716
0.110
Why?
Protein Kinases
1
2015
318
0.110
Why?
Genotype
1
2018
1829
0.110
Why?
Receptor, Insulin
1
2013
99
0.100
Why?
Protein-Tyrosine Kinases
1
2017
431
0.100
Why?
Phenotype
3
2018
3062
0.100
Why?
Cell Survival
4
2019
1086
0.100
Why?
Ubiquitin-Conjugating Enzymes
1
2013
13
0.100
Why?
Tumor Stem Cell Assay
1
2012
32
0.100
Why?
Aurora Kinases
1
2012
27
0.100
Why?
Cyclin-Dependent Kinase Inhibitor p16
1
2013
66
0.100
Why?
BRCA1 Protein
1
2013
65
0.100
Why?
Proto-Oncogene Proteins c-ets
4
2011
53
0.100
Why?
Alcohol Oxidoreductases
1
2013
58
0.100
Why?
Mitochondria
1
2018
875
0.100
Why?
Rats
21
2004
5485
0.100
Why?
Genes, p53
1
2012
70
0.100
Why?
Positron-Emission Tomography
2
2011
282
0.100
Why?
Receptor, ErbB-2
2
2012
325
0.100
Why?
MicroRNAs
1
2018
680
0.100
Why?
Cyclosporine
1
2013
263
0.100
Why?
TOR Serine-Threonine Kinases
1
2014
398
0.090
Why?
Proto-Oncogene Proteins c-met
1
2012
74
0.090
Why?
Ubiquitin-Protein Ligases
1
2013
156
0.090
Why?
Drug Screening Assays, Antitumor
4
2016
191
0.090
Why?
Proteasome Inhibitors
1
2011
42
0.090
Why?
Polymorphism, Single Nucleotide
1
2018
2062
0.090
Why?
Mammary Glands, Human
1
2011
63
0.090
Why?
Cellular Senescence
1
2012
173
0.090
Why?
Receptor Protein-Tyrosine Kinases
1
2013
231
0.090
Why?
Transcriptional Activation
2
2003
366
0.090
Why?
Cytoplasm
1
2011
269
0.090
Why?
Recombinant Fusion Proteins
2
2011
650
0.090
Why?
Cell Movement
3
2011
950
0.080
Why?
Protease Inhibitors
1
2011
107
0.080
Why?
Vascular Endothelial Growth Factor Receptor-3
1
2009
7
0.080
Why?
Ki-67 Antigen
1
2010
108
0.080
Why?
Neoplasm Transplantation
3
2016
253
0.080
Why?
Capillary Permeability
1
2010
141
0.080
Why?
Vascular Endothelial Growth Factor Receptor-1
1
2009
70
0.080
Why?
Adenocarcinoma
1
2016
893
0.080
Why?
Gastrointestinal Neoplasms
1
2009
72
0.080
Why?
Carcinoma, Hepatocellular
1
2011
270
0.080
Why?
Cell Line
4
2012
2779
0.070
Why?
Quinazolines
1
2009
243
0.070
Why?
Promoter Regions, Genetic
3
2004
1213
0.070
Why?
Algorithms
2
2015
1616
0.070
Why?
Peptide Fragments
1
2011
695
0.070
Why?
Drug Delivery Systems
1
2010
337
0.070
Why?
Enzyme Inhibitors
3
2013
827
0.070
Why?
Pituitary Gland, Anterior
4
1992
39
0.070
Why?
Prognosis
2
2017
3772
0.070
Why?
Colonic Neoplasms
1
2009
241
0.060
Why?
Proto-Oncogene Protein c-ets-1
2
2003
19
0.060
Why?
Disease Models, Animal
2
2014
4076
0.060
Why?
Reproducibility of Results
2
2010
3084
0.060
Why?
Growth Hormone-Releasing Hormone
2
1997
24
0.060
Why?
Rats, Inbred Strains
12
1992
368
0.060
Why?
Transplantation, Heterologous
2
2016
191
0.060
Why?
Oncogene Protein p65(gag-jun)
1
2004
2
0.060
Why?
Male
25
2020
63691
0.060
Why?
Proto-Oncogene Proteins c-jun
1
2004
52
0.060
Why?
Gene Expression Regulation
2
2004
2545
0.060
Why?
Transfection
2
2003
918
0.050
Why?
High-Throughput Nucleotide Sequencing
2
2017
486
0.050
Why?
Pancreatic Neoplasms
1
2011
879
0.050
Why?
Transcription Factor Pit-1
1
2003
24
0.050
Why?
Disease Progression
3
2018
2628
0.050
Why?
Suppression, Genetic
1
2003
25
0.050
Why?
Lung Neoplasms
1
2016
2343
0.050
Why?
Mesoderm
1
2004
138
0.050
Why?
Genes, Dominant
1
2003
94
0.050
Why?
Histone Deacetylase 1
1
2022
24
0.050
Why?
DNA Repair
2
2013
210
0.050
Why?
Middle Aged
6
2020
31165
0.050
Why?
Caspase 3
2
2013
244
0.050
Why?
Aged
5
2020
22101
0.050
Why?
Blotting, Northern
3
1997
196
0.050
Why?
DNA Damage
2
2013
383
0.050
Why?
Acetylation
1
2022
244
0.040
Why?
Repressor Proteins
1
2004
404
0.040
Why?
Radioimmunoassay
8
1993
175
0.040
Why?
Histone Deacetylases
1
2022
212
0.040
Why?
Bortezomib
2
2011
45
0.040
Why?
Mechanistic Target of Rapamycin Complex 2
1
2020
62
0.040
Why?
Maximum Tolerated Dose
1
2020
193
0.040
Why?
Mechanistic Target of Rapamycin Complex 1
1
2020
118
0.040
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2019
40
0.040
Why?
Blotting, Western
3
2010
1204
0.040
Why?
Gene Expression
3
1993
1465
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
24
0.040
Why?
Azetidines
1
2018
40
0.040
Why?
Spleen
2
1991
508
0.040
Why?
Lymphocytes
2
1991
377
0.040
Why?
GTP Phosphohydrolases
1
2018
86
0.040
Why?
4-Aminobenzoic Acid
1
2018
7
0.040
Why?
Nausea
1
2018
111
0.040
Why?
HCT116 Cells
1
2018
76
0.040
Why?
Okadaic Acid
1
1997
14
0.030
Why?
Orchiectomy
4
1994
67
0.030
Why?
Enzyme-Linked Immunosorbent Assay
2
2010
836
0.030
Why?
Colforsin
1
1997
50
0.030
Why?
Mutagenesis, Site-Directed
2
2011
363
0.030
Why?
Diarrhea
1
2018
181
0.030
Why?
Dose-Response Relationship, Drug
3
1997
2014
0.030
Why?
Piperidines
1
2018
200
0.030
Why?
Angiogenesis Inhibitors
1
2018
218
0.030
Why?
Tumor Burden
1
2018
286
0.030
Why?
Histones
1
2022
588
0.030
Why?
Cells, Cultured
4
2013
4102
0.030
Why?
Ubiquitination
1
2016
98
0.030
Why?
Cell Differentiation
1
2004
1900
0.030
Why?
Fatigue
1
2018
319
0.030
Why?
Heterografts
1
2016
133
0.030
Why?
Treatment Outcome
1
2010
10221
0.030
Why?
Cetuximab
1
2016
94
0.030
Why?
Administration, Oral
1
2018
787
0.030
Why?
Protein Isoforms
1
2017
393
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
117
0.030
Why?
Camptothecin
1
2016
110
0.030
Why?
Gene Rearrangement
1
2017
148
0.030
Why?
Polymerase Chain Reaction
3
1993
1033
0.030
Why?
Aged, 80 and over
2
2017
7064
0.030
Why?
Models, Educational
1
2015
91
0.030
Why?
Capacity Building
1
2015
59
0.030
Why?
DNA Copy Number Variations
1
2016
167
0.030
Why?
Diphenylamine
1
2014
9
0.030
Why?
DNA Mutational Analysis
1
2016
379
0.030
Why?
Biopsy
1
2018
1087
0.030
Why?
Interdisciplinary Communication
1
2015
186
0.030
Why?
Databases, Genetic
1
2015
228
0.030
Why?
Follicle Stimulating Hormone
2
1993
237
0.030
Why?
Guanine
1
1994
76
0.030
Why?
Research Personnel
1
2015
156
0.030
Why?
Neoplasm Metastasis
1
2016
610
0.030
Why?
Analysis of Variance
1
1997
1290
0.030
Why?
Methyltransferases
1
1994
70
0.030
Why?
Gonadotropins
1
1993
38
0.030
Why?
Adult
4
2018
35607
0.030
Why?
Benzamides
1
2014
203
0.030
Why?
Caspase 7
1
2013
22
0.030
Why?
Mentors
1
2015
177
0.030
Why?
MAP Kinase Kinase 2
1
2013
28
0.030
Why?
Butadienes
1
2013
36
0.030
Why?
Program Development
1
2015
355
0.030
Why?
MAP Kinase Kinase 1
1
2013
75
0.030
Why?
Kinetics
2
2014
1645
0.030
Why?
Cell Cycle Checkpoints
1
2013
95
0.030
Why?
Oncogene Proteins, Viral
1
2013
22
0.030
Why?
Molecular Sequence Data
3
2011
2833
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p27
1
2013
74
0.030
Why?
Cooperative Behavior
1
2015
432
0.030
Why?
Melanocytes
1
2013
65
0.030
Why?
Nitriles
1
2013
169
0.020
Why?
Drug Hypersensitivity
1
1993
81
0.020
Why?
Genes, Synthetic
1
2012
15
0.020
Why?
Phosphatidylinositol 3-Kinases
1
2014
362
0.020
Why?
Genes, Lethal
1
2012
29
0.020
Why?
Proto-Oncogene Proteins c-mdm2
1
2013
63
0.020
Why?
DNA, Neoplasm
1
2013
154
0.020
Why?
Membrane Proteins
1
2018
1119
0.020
Why?
Mice, SCID
1
2013
350
0.020
Why?
Precision Medicine
1
2016
385
0.020
Why?
Ataxia Telangiectasia Mutated Proteins
1
2012
65
0.020
Why?
Nuclear Export Signals
1
2011
4
0.020
Why?
Glycoprotein Hormones, alpha Subunit
1
1991
22
0.020
Why?
Nuclear Localization Signals
1
2011
15
0.020
Why?
Alcoholic Intoxication
1
1992
64
0.020
Why?
Peptide Mapping
1
2011
64
0.020
Why?
Microscopy, Fluorescence
1
2013
399
0.020
Why?
Intercellular Signaling Peptides and Proteins
1
2013
373
0.020
Why?
Calcium Signaling
1
2013
252
0.020
Why?
Amino Acid Motifs
1
2011
215
0.020
Why?
Colony-Forming Units Assay
1
2010
90
0.020
Why?
Amino Acid Substitution
1
2011
284
0.020
Why?
Culture Media, Conditioned
1
2010
110
0.020
Why?
Genes, ras
1
2010
95
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
260
0.020
Why?
Protein Biosynthesis
1
1992
406
0.020
Why?
Protein Transport
1
2011
429
0.020
Why?
Ligands
1
2011
621
0.020
Why?
Gene Dosage
1
2010
143
0.020
Why?
Transcriptome
1
2015
875
0.020
Why?
Drug Combinations
1
2010
331
0.020
Why?
Structure-Activity Relationship
1
2010
547
0.020
Why?
Hypertension
1
2018
1242
0.020
Why?
Gene Knockdown Techniques
1
2010
317
0.020
Why?
Prolactinoma
1
1989
12
0.020
Why?
Curriculum
1
2015
925
0.020
Why?
Serum Albumin
1
1990
149
0.020
Why?
Protein Structure, Tertiary
1
2011
844
0.020
Why?
Magnetic Resonance Spectroscopy
1
2011
541
0.020
Why?
Immunohistochemistry
1
2013
1690
0.020
Why?
Cell Communication
1
2010
301
0.020
Why?
Proto-Oncogene Proteins c-akt
1
2010
434
0.020
Why?
Follow-Up Studies
1
2017
4892
0.020
Why?
Pregnanediones
1
1987
7
0.020
Why?
Rats, Sprague-Dawley
4
1994
2403
0.020
Why?
Amino Acid Sequence
1
2011
2057
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2009
953
0.020
Why?
Sulfonamides
1
2011
497
0.020
Why?
Brain Chemistry
1
1987
118
0.020
Why?
Anesthetics
1
1987
66
0.020
Why?
Pituitary Neoplasms
1
1989
180
0.020
Why?
Calcium
1
2013
1212
0.020
Why?
Feasibility Studies
1
2010
869
0.020
Why?
Estrogens
1
1989
348
0.020
Why?
Liver Neoplasms
1
2011
636
0.020
Why?
Models, Biological
1
2013
1724
0.020
Why?
Metabolomics
1
2011
652
0.020
Why?
Flow Cytometry
1
2009
1160
0.020
Why?
Prostatic Neoplasms
1
2013
999
0.010
Why?
Proto-Oncogene Protein c-ets-2
1
2004
3
0.010
Why?
Contact Inhibition
1
2004
5
0.010
Why?
Oncogene Protein p21(ras)
1
2004
16
0.010
Why?
Epidermal Growth Factor
1
2004
170
0.010
Why?
Antisense Elements (Genetics)
1
2003
4
0.010
Why?
Collagenases
1
2003
24
0.010
Why?
Matrix Metalloproteinase 3
1
2003
26
0.010
Why?
Genetic Vectors
1
2004
312
0.010
Why?
Cell Adhesion
1
2004
454
0.010
Why?
Cytokines
1
2010
2022
0.010
Why?
Cell Division
1
2004
790
0.010
Why?
Trans-Activators
1
2004
392
0.010
Why?
HeLa Cells
1
2003
611
0.010
Why?
Brain
1
1992
2677
0.010
Why?
Potassium
2
1990
144
0.010
Why?
Base Sequence
2
1993
2142
0.010
Why?
Biological Assay
2
1990
119
0.010
Why?
Hypophysectomy
2
1987
15
0.010
Why?
O(6)-Methylguanine-DNA Methyltransferase
1
1994
6
0.010
Why?
Cocarcinogenesis
1
1994
14
0.010
Why?
Injections, Intraperitoneal
1
1994
112
0.010
Why?
Rats, Mutant Strains
1
1993
25
0.010
Why?
Thyrotropin
1
1994
109
0.010
Why?
Stress, Physiological
2
1987
411
0.010
Why?
RNA-Directed DNA Polymerase
1
1993
34
0.010
Why?
Adrenocorticotropic Hormone
1
1994
133
0.010
Why?
Blotting, Southern
1
1992
70
0.010
Why?
Cyclic AMP
1
1992
238
0.010
Why?
Protein Kinase C
1
1992
262
0.010
Why?
Enzyme Activation
1
1992
812
0.010
Why?
RNA Splicing
1
1992
259
0.010
Why?
Cross Reactions
1
1990
133
0.010
Why?
Dinoprostone
1
1990
187
0.000
Why?
Bromocriptine
1
1989
30
0.000
Why?
Norepinephrine
1
1990
209
0.000
Why?
Perfusion
1
1990
197
0.000
Why?
Naloxone
1
1990
112
0.000
Why?
Rats, Inbred F344
1
1989
256
0.000
Why?
Depression, Chemical
1
1987
23
0.000
Why?
Chromatography, High Pressure Liquid
1
1990
581
0.000
Why?
In Vitro Techniques
1
1990
1090
0.000
Why?
Urethane
1
1987
41
0.000
Why?
Pancreas
1
1990
305
0.000
Why?
Molecular Weight
1
1987
330
0.000
Why?
Drug Administration Schedule
1
1989
766
0.000
Why?
Dopamine
1
1990
286
0.000
Why?
Ketamine
1
1987
85
0.000
Why?
Cerebral Cortex
1
1990
439
0.000
Why?
Alcoholism
1
1992
766
0.000
Why?
Restraint, Physical
1
1986
67
0.000
Why?
DNA
1
1991
1406
0.000
Why?
Kidney
1
1990
1383
0.000
Why?
Liver
1
1990
1839
0.000
Why?
Lung
1
1990
3937
0.000
Why?
Tentler's Networks
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