Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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John Tentler

Concepts (387)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Pyrimidines
8
2020
376
1.650
Why?
Xenograft Model Antitumor Assays
21
2020
704
1.440
Why?
Triple Negative Breast Neoplasms
5
2020
157
1.430
Why?
Protein Kinase Inhibitors
15
2020
790
1.400
Why?
Antineoplastic Agents
18
2019
1893
1.310
Why?
Colorectal Neoplasms
11
2018
617
1.140
Why?
Proto-Oncogene Proteins
10
2018
609
1.020
Why?
Azepines
4
2020
74
0.940
Why?
Piperazines
4
2020
314
0.920
Why?
Quinoxalines
2
2020
61
0.870
Why?
Pyrazoles
4
2018
362
0.870
Why?
Melanoma
10
2018
651
0.860
Why?
Gene Expression Regulation, Neoplastic
9
2020
1147
0.850
Why?
Mice, Nude
16
2020
639
0.740
Why?
Cell Proliferation
21
2020
2194
0.700
Why?
Lymphocytes, Tumor-Infiltrating
1
2020
111
0.690
Why?
beta Catenin
2
2020
220
0.680
Why?
Enoyl-CoA Hydratase
1
2018
9
0.650
Why?
DNA-Binding Proteins
8
2015
1316
0.610
Why?
Cell Line, Tumor
24
2020
2751
0.600
Why?
Tumor Microenvironment
1
2020
431
0.600
Why?
Benzimidazoles
4
2013
137
0.560
Why?
Mutation
11
2018
3364
0.540
Why?
Cardiomyopathy, Dilated
1
2018
352
0.520
Why?
Tumor Suppressor Proteins
2
2015
286
0.510
Why?
Tumor Suppressor Protein p53
4
2016
449
0.510
Why?
ras Proteins
3
2013
138
0.460
Why?
Genomics
1
2018
646
0.460
Why?
Pyrazines
5
2013
70
0.450
Why?
Proto-Oncogene Proteins B-raf
4
2018
192
0.420
Why?
Apoptosis
13
2020
2377
0.400
Why?
Oncogene Proteins, Fusion
3
2018
178
0.390
Why?
Biomarkers, Tumor
3
2017
1048
0.380
Why?
Mice
21
2020
15052
0.380
Why?
Drug Design
1
2012
156
0.380
Why?
Nuclear Proteins
1
2015
594
0.360
Why?
Prolactin
7
2004
95
0.360
Why?
Drug Resistance, Neoplasm
8
2020
638
0.360
Why?
Mitogen-Activated Protein Kinase Kinases
1
2010
114
0.350
Why?
Histone Deacetylase Inhibitors
3
2022
199
0.350
Why?
Aurora Kinase A
4
2020
51
0.340
Why?
Animals
44
2020
32102
0.320
Why?
Neoplasms
4
2022
2118
0.310
Why?
Cell Transformation, Neoplastic
4
2013
314
0.300
Why?
Imidazoles
4
2013
217
0.290
Why?
Pituitary Gland
7
2003
152
0.290
Why?
Ethanol
11
1997
549
0.270
Why?
Gene Expression Profiling
6
2018
1536
0.270
Why?
Hydroxamic Acids
3
2011
80
0.270
Why?
Antineoplastic Combined Chemotherapy Protocols
6
2020
1361
0.260
Why?
Exome
2
2017
202
0.260
Why?
Breast Neoplasms
3
2012
1872
0.250
Why?
Ubiquitin-Activating Enzymes
2
2016
13
0.250
Why?
Transcription Factors
4
2011
1528
0.240
Why?
Pyrimidinones
2
2015
88
0.240
Why?
Pyridones
2
2015
125
0.230
Why?
Receptor, IGF Type 1
3
2013
58
0.220
Why?
Humans
44
2022
115611
0.220
Why?
Cell Cycle Proteins
3
2018
553
0.210
Why?
Hypothalamus
12
1997
150
0.200
Why?
Immunoblotting
5
2015
281
0.200
Why?
Drug Synergism
4
2018
317
0.200
Why?
Female
27
2020
59931
0.190
Why?
Tumor Cells, Cultured
3
2020
850
0.190
Why?
c-Mer Tyrosine Kinase
2
2018
43
0.190
Why?
Transcription, Genetic
4
2013
1310
0.190
Why?
G2 Phase Cell Cycle Checkpoints
3
2018
41
0.180
Why?
Signal Transduction
10
2018
4541
0.180
Why?
Benzoxazoles
1
2020
16
0.180
Why?
Breast
3
2018
138
0.180
Why?
Wnt Signaling Pathway
2
2019
148
0.180
Why?
Boronic Acids
2
2011
33
0.170
Why?
Growth Hormone
3
1997
99
0.170
Why?
Epithelial Cells
4
2011
961
0.170
Why?
Sequence Analysis, RNA
2
2018
390
0.170
Why?
eIF-2 Kinase
1
2019
24
0.170
Why?
Proto-Oncogene Proteins p21(ras)
4
2016
228
0.160
Why?
Cell Cycle
7
2018
546
0.160
Why?
Breast Neoplasms, Male
1
2018
28
0.160
Why?
Cytochrome P-450 Enzyme System
1
2018
108
0.160
Why?
Linkage Disequilibrium
1
2018
247
0.150
Why?
MAP Kinase Kinase Kinases
2
2015
68
0.150
Why?
Septins
1
2018
40
0.150
Why?
Mice, Inbred BALB C
1
2020
1168
0.150
Why?
Drug Therapy, Combination
1
2020
962
0.150
Why?
Cytoskeleton
1
2018
177
0.150
Why?
Genetics, Population
1
2018
192
0.150
Why?
Gonadotropin-Releasing Hormone
8
1993
193
0.150
Why?
Neurofibromin 1
1
2017
22
0.140
Why?
Somatostatin
1
1997
53
0.140
Why?
Armadillo Domain Proteins
1
2017
5
0.140
Why?
Gene Regulatory Networks
1
2018
231
0.140
Why?
Proto-Oncogene Proteins c-kit
1
2017
63
0.140
Why?
Adenine
1
2018
221
0.140
Why?
Testis
2
1997
134
0.140
Why?
Proto-Oncogene Proteins c-ret
1
2017
24
0.140
Why?
RNA Splicing Factors
1
2017
50
0.140
Why?
Cyclopentanes
1
2016
15
0.140
Why?
Sexual Maturation
1
1997
47
0.140
Why?
Inhibitory Concentration 50
2
2016
77
0.140
Why?
Mucous Membrane
1
2017
109
0.140
Why?
Cyclic AMP Response Element-Binding Protein
1
1997
128
0.140
Why?
Cyclic AMP-Dependent Protein Kinases
1
1997
131
0.140
Why?
Genes, erbB-1
1
2016
18
0.130
Why?
RNA, Messenger
10
2003
2574
0.130
Why?
Education, Graduate
1
2015
32
0.130
Why?
Skin Neoplasms
2
2013
761
0.130
Why?
Oligonucleotide Array Sequence Analysis
3
2015
746
0.130
Why?
Drug Discovery
1
2016
124
0.130
Why?
HT29 Cells
2
2018
36
0.130
Why?
Peptides, Cyclic
1
1997
262
0.130
Why?
Tumor Protein p73
1
2015
15
0.130
Why?
Proteasome Endopeptidase Complex
2
2013
136
0.130
Why?
Neoplasm Invasiveness
3
2018
445
0.130
Why?
Computational Biology
2
2016
537
0.120
Why?
Phosphoproteins
1
2017
304
0.120
Why?
Mitogen-Activated Protein Kinases
2
2014
277
0.120
Why?
Case-Control Studies
2
2018
3023
0.120
Why?
Testosterone
2
1997
337
0.120
Why?
Luteinizing Hormone
8
1993
169
0.120
Why?
Cluster Analysis
2
2012
465
0.120
Why?
Phosphorylation
5
2019
1571
0.110
Why?
Phenotype
3
2018
2831
0.110
Why?
Genotype
1
2018
1787
0.110
Why?
Protein Kinases
1
2015
306
0.110
Why?
Protein-Tyrosine Kinases
1
2017
396
0.110
Why?
Receptor, Insulin
1
2013
93
0.110
Why?
Mitochondria
1
2018
750
0.110
Why?
Ubiquitin-Conjugating Enzymes
1
2013
9
0.110
Why?
Cell Survival
4
2019
1024
0.110
Why?
Tumor Stem Cell Assay
1
2012
33
0.110
Why?
Aurora Kinases
1
2012
28
0.110
Why?
Cyclin-Dependent Kinase Inhibitor p16
1
2013
58
0.110
Why?
Alcohol Oxidoreductases
1
2013
38
0.110
Why?
Rats
21
2004
5034
0.110
Why?
BRCA1 Protein
1
2013
57
0.100
Why?
Cyclosporine
1
2013
169
0.100
Why?
Proto-Oncogene Proteins c-ets
4
2011
51
0.100
Why?
MicroRNAs
1
2018
607
0.100
Why?
Receptor, ErbB-2
2
2012
302
0.100
Why?
Genes, p53
1
2012
62
0.100
Why?
Positron-Emission Tomography
2
2011
284
0.100
Why?
TOR Serine-Threonine Kinases
1
2014
362
0.100
Why?
Proto-Oncogene Proteins c-met
1
2012
67
0.100
Why?
Ubiquitin-Protein Ligases
1
2013
139
0.100
Why?
Cellular Senescence
1
2012
153
0.100
Why?
Drug Screening Assays, Antitumor
4
2016
180
0.090
Why?
Polymorphism, Single Nucleotide
1
2018
1918
0.090
Why?
Proteasome Inhibitors
1
2011
40
0.090
Why?
Mammary Glands, Human
1
2011
60
0.090
Why?
Receptor Protein-Tyrosine Kinases
1
2013
225
0.090
Why?
Transcriptional Activation
2
2003
340
0.090
Why?
Cytoplasm
1
2011
255
0.090
Why?
Cell Movement
3
2011
867
0.090
Why?
Recombinant Fusion Proteins
2
2011
616
0.090
Why?
Protease Inhibitors
1
2011
101
0.090
Why?
Vascular Endothelial Growth Factor Receptor-3
1
2009
6
0.090
Why?
Neoplasm Transplantation
3
2016
235
0.090
Why?
Ki-67 Antigen
1
2010
104
0.090
Why?
Capillary Permeability
1
2010
138
0.090
Why?
Adenocarcinoma
1
2016
799
0.080
Why?
Vascular Endothelial Growth Factor Receptor-1
1
2009
68
0.080
Why?
Carcinoma, Hepatocellular
1
2011
224
0.080
Why?
Gastrointestinal Neoplasms
1
2009
59
0.080
Why?
Cell Line
4
2012
2651
0.080
Why?
Promoter Regions, Genetic
3
2004
1122
0.080
Why?
Quinazolines
1
2009
241
0.080
Why?
Algorithms
2
2015
1490
0.070
Why?
Prognosis
2
2017
3339
0.070
Why?
Drug Delivery Systems
1
2010
301
0.070
Why?
Peptide Fragments
1
2011
675
0.070
Why?
Enzyme Inhibitors
3
2013
757
0.070
Why?
Pituitary Gland, Anterior
4
1992
41
0.070
Why?
Disease Models, Animal
2
2014
3580
0.070
Why?
Colonic Neoplasms
1
2009
222
0.070
Why?
Proto-Oncogene Protein c-ets-1
2
2003
18
0.070
Why?
Reproducibility of Results
2
2010
2800
0.070
Why?
Male
25
2020
55967
0.060
Why?
Growth Hormone-Releasing Hormone
2
1997
27
0.060
Why?
Rats, Inbred Strains
12
1992
376
0.060
Why?
Transplantation, Heterologous
2
2016
187
0.060
Why?
Oncogene Protein p65(gag-jun)
1
2004
2
0.060
Why?
Gene Expression Regulation
2
2004
2353
0.060
Why?
Proto-Oncogene Proteins c-jun
1
2004
47
0.060
Why?
Pancreatic Neoplasms
1
2011
722
0.060
Why?
High-Throughput Nucleotide Sequencing
2
2017
443
0.060
Why?
Transfection
2
2003
866
0.060
Why?
Disease Progression
3
2018
2418
0.060
Why?
Lung Neoplasms
1
2016
2207
0.050
Why?
Transcription Factor Pit-1
1
2003
24
0.050
Why?
Suppression, Genetic
1
2003
23
0.050
Why?
Middle Aged
6
2020
27014
0.050
Why?
Mesoderm
1
2004
138
0.050
Why?
Genes, Dominant
1
2003
93
0.050
Why?
Aged
5
2020
19255
0.050
Why?
Histone Deacetylase 1
1
2022
16
0.050
Why?
DNA Repair
2
2013
190
0.050
Why?
Caspase 3
2
2013
237
0.050
Why?
Acetylation
1
2022
212
0.050
Why?
DNA Damage
2
2013
357
0.050
Why?
Blotting, Northern
3
1997
194
0.050
Why?
Repressor Proteins
1
2004
369
0.050
Why?
Radioimmunoassay
8
1993
163
0.040
Why?
Histone Deacetylases
1
2022
196
0.040
Why?
Bortezomib
2
2011
41
0.040
Why?
Mechanistic Target of Rapamycin Complex 2
1
2020
57
0.040
Why?
Maximum Tolerated Dose
1
2020
182
0.040
Why?
Mechanistic Target of Rapamycin Complex 1
1
2020
99
0.040
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2019
22
0.040
Why?
Blotting, Western
3
2010
1153
0.040
Why?
Spleen
2
1991
492
0.040
Why?
Gene Expression
3
1993
1436
0.040
Why?
Lymphocytes
2
1991
344
0.040
Why?
Azetidines
1
2018
31
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
23
0.040
Why?
GTP Phosphohydrolases
1
2018
66
0.040
Why?
4-Aminobenzoic Acid
1
2018
6
0.040
Why?
Nausea
1
2018
103
0.040
Why?
HCT116 Cells
1
2018
69
0.040
Why?
Enzyme-Linked Immunosorbent Assay
2
2010
795
0.040
Why?
Orchiectomy
4
1994
57
0.040
Why?
Okadaic Acid
1
1997
11
0.040
Why?
Colforsin
1
1997
46
0.040
Why?
Piperidines
1
2018
163
0.040
Why?
Diarrhea
1
2018
173
0.040
Why?
Dose-Response Relationship, Drug
3
1997
1870
0.040
Why?
Mutagenesis, Site-Directed
2
2011
346
0.040
Why?
Histones
1
2022
540
0.040
Why?
Tumor Burden
1
2018
261
0.040
Why?
Cell Differentiation
1
2004
1700
0.030
Why?
Angiogenesis Inhibitors
1
2018
216
0.030
Why?
Treatment Outcome
1
2010
9159
0.030
Why?
Cells, Cultured
4
2013
3914
0.030
Why?
Fatigue
1
2018
296
0.030
Why?
Ubiquitination
1
2016
86
0.030
Why?
Protein Isoforms
1
2017
339
0.030
Why?
Heterografts
1
2016
119
0.030
Why?
Administration, Oral
1
2018
734
0.030
Why?
Gene Rearrangement
1
2017
135
0.030
Why?
Cetuximab
1
2016
90
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
107
0.030
Why?
Camptothecin
1
2016
97
0.030
Why?
Aged, 80 and over
2
2017
6419
0.030
Why?
Polymerase Chain Reaction
3
1993
1001
0.030
Why?
Capacity Building
1
2015
51
0.030
Why?
Models, Educational
1
2015
86
0.030
Why?
DNA Copy Number Variations
1
2016
156
0.030
Why?
Adult
4
2018
30726
0.030
Why?
Diphenylamine
1
2014
6
0.030
Why?
DNA Mutational Analysis
1
2016
372
0.030
Why?
Follicle Stimulating Hormone
2
1993
214
0.030
Why?
Biopsy
1
2018
1056
0.030
Why?
Databases, Genetic
1
2015
208
0.030
Why?
Interdisciplinary Communication
1
2015
185
0.030
Why?
Neoplasm Metastasis
1
2016
526
0.030
Why?
Guanine
1
1994
76
0.030
Why?
Methyltransferases
1
1994
61
0.030
Why?
Benzamides
1
2014
168
0.030
Why?
Research Personnel
1
2015
153
0.030
Why?
Analysis of Variance
1
1997
1227
0.030
Why?
Mentors
1
2015
162
0.030
Why?
Gonadotropins
1
1993
37
0.030
Why?
Caspase 7
1
2013
22
0.030
Why?
MAP Kinase Kinase 2
1
2013
27
0.030
Why?
Butadienes
1
2013
31
0.030
Why?
Program Development
1
2015
350
0.030
Why?
Kinetics
2
2014
1569
0.030
Why?
MAP Kinase Kinase 1
1
2013
66
0.030
Why?
Cell Cycle Checkpoints
1
2013
84
0.030
Why?
Cooperative Behavior
1
2015
390
0.030
Why?
Oncogene Proteins, Viral
1
2013
20
0.030
Why?
Melanocytes
1
2013
55
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p27
1
2013
69
0.030
Why?
Nitriles
1
2013
152
0.030
Why?
Molecular Sequence Data
3
2011
2790
0.030
Why?
Phosphatidylinositol 3-Kinases
1
2014
332
0.030
Why?
Membrane Proteins
1
2018
1024
0.030
Why?
Proto-Oncogene Proteins c-mdm2
1
2013
57
0.030
Why?
Genes, Synthetic
1
2012
14
0.030
Why?
Genes, Lethal
1
2012
25
0.030
Why?
Drug Hypersensitivity
1
1993
86
0.030
Why?
Precision Medicine
1
2016
344
0.030
Why?
DNA, Neoplasm
1
2013
157
0.030
Why?
Mice, SCID
1
2013
321
0.030
Why?
Ataxia Telangiectasia Mutated Proteins
1
2012
63
0.030
Why?
Nuclear Export Signals
1
2011
3
0.020
Why?
Glycoprotein Hormones, alpha Subunit
1
1991
22
0.020
Why?
Nuclear Localization Signals
1
2011
14
0.020
Why?
Alcoholic Intoxication
1
1992
63
0.020
Why?
Peptide Mapping
1
2011
59
0.020
Why?
Calcium Signaling
1
2013
211
0.020
Why?
Microscopy, Fluorescence
1
2013
402
0.020
Why?
Intercellular Signaling Peptides and Proteins
1
2013
350
0.020
Why?
Amino Acid Motifs
1
2011
198
0.020
Why?
Amino Acid Substitution
1
2011
267
0.020
Why?
Colony-Forming Units Assay
1
2010
90
0.020
Why?
Protein Biosynthesis
1
1992
390
0.020
Why?
Hypertension
1
2018
1064
0.020
Why?
Culture Media, Conditioned
1
2010
105
0.020
Why?
Transcriptome
1
2015
736
0.020
Why?
Genes, ras
1
2010
91
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
238
0.020
Why?
Protein Transport
1
2011
400
0.020
Why?
Ligands
1
2011
569
0.020
Why?
Gene Dosage
1
2010
129
0.020
Why?
Drug Combinations
1
2010
289
0.020
Why?
Curriculum
1
2015
853
0.020
Why?
Structure-Activity Relationship
1
2010
511
0.020
Why?
Gene Knockdown Techniques
1
2010
302
0.020
Why?
Prolactinoma
1
1989
11
0.020
Why?
Serum Albumin
1
1990
135
0.020
Why?
Protein Structure, Tertiary
1
2011
804
0.020
Why?
Magnetic Resonance Spectroscopy
1
2011
482
0.020
Why?
Immunohistochemistry
1
2013
1642
0.020
Why?
Cell Communication
1
2010
282
0.020
Why?
Follow-Up Studies
1
2017
4440
0.020
Why?
Proto-Oncogene Proteins c-akt
1
2010
400
0.020
Why?
Rats, Sprague-Dawley
4
1994
2262
0.020
Why?
Pregnanediones
1
1987
1
0.020
Why?
Sulfonamides
1
2011
447
0.020
Why?
Pituitary Neoplasms
1
1989
157
0.020
Why?
Anesthetics
1
1987
57
0.020
Why?
Calcium
1
2013
1103
0.020
Why?
Amino Acid Sequence
1
2011
2000
0.020
Why?
Feasibility Studies
1
2010
741
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2009
930
0.020
Why?
Brain Chemistry
1
1987
116
0.020
Why?
Liver Neoplasms
1
2011
521
0.020
Why?
Metabolomics
1
2011
538
0.020
Why?
Estrogens
1
1989
315
0.020
Why?
Models, Biological
1
2013
1646
0.020
Why?
Flow Cytometry
1
2009
1083
0.020
Why?
Prostatic Neoplasms
1
2013
927
0.020
Why?
Proto-Oncogene Protein c-ets-2
1
2004
3
0.010
Why?
Contact Inhibition
1
2004
3
0.010
Why?
Oncogene Protein p21(ras)
1
2004
16
0.010
Why?
Epidermal Growth Factor
1
2004
161
0.010
Why?
Antisense Elements (Genetics)
1
2003
5
0.010
Why?
Collagenases
1
2003
22
0.010
Why?
Genetic Vectors
1
2004
290
0.010
Why?
Matrix Metalloproteinase 3
1
2003
23
0.010
Why?
Cytokines
1
2010
1853
0.010
Why?
Cell Adhesion
1
2004
433
0.010
Why?
Cell Division
1
2004
759
0.010
Why?
Trans-Activators
1
2004
370
0.010
Why?
HeLa Cells
1
2003
567
0.010
Why?
Brain
1
1992
2373
0.010
Why?
Potassium
2
1990
128
0.010
Why?
Base Sequence
2
1993
2114
0.010
Why?
Biological Assay
2
1990
114
0.010
Why?
Hypophysectomy
2
1987
15
0.010
Why?
O(6)-Methylguanine-DNA Methyltransferase
1
1994
5
0.010
Why?
Cocarcinogenesis
1
1994
14
0.010
Why?
Injections, Intraperitoneal
1
1994
104
0.010
Why?
Rats, Mutant Strains
1
1993
25
0.010
Why?
Thyrotropin
1
1994
100
0.010
Why?
Stress, Physiological
2
1987
399
0.010
Why?
RNA-Directed DNA Polymerase
1
1993
34
0.010
Why?
Adrenocorticotropic Hormone
1
1994
148
0.010
Why?
Blotting, Southern
1
1992
66
0.010
Why?
Cyclic AMP
1
1992
227
0.010
Why?
Protein Kinase C
1
1992
274
0.010
Why?
Enzyme Activation
1
1992
793
0.010
Why?
RNA Splicing
1
1992
244
0.010
Why?
Cross Reactions
1
1990
117
0.010
Why?
Perfusion
1
1990
150
0.010
Why?
Dinoprostone
1
1990
186
0.010
Why?
Bromocriptine
1
1989
27
0.010
Why?
Naloxone
1
1990
99
0.010
Why?
Norepinephrine
1
1990
207
0.010
Why?
Chromatography, High Pressure Liquid
1
1990
477
0.000
Why?
Rats, Inbred F344
1
1989
245
0.000
Why?
Depression, Chemical
1
1987
23
0.000
Why?
In Vitro Techniques
1
1990
1044
0.000
Why?
Urethane
1
1987
41
0.000
Why?
Pancreas
1
1990
280
0.000
Why?
Dopamine
1
1990
237
0.000
Why?
Molecular Weight
1
1987
329
0.000
Why?
Drug Administration Schedule
1
1989
724
0.000
Why?
Cerebral Cortex
1
1990
386
0.000
Why?
Ketamine
1
1987
92
0.000
Why?
Alcoholism
1
1992
717
0.000
Why?
Restraint, Physical
1
1986
92
0.000
Why?
DNA
1
1991
1356
0.000
Why?
Kidney
1
1990
1207
0.000
Why?
Liver
1
1990
1690
0.000
Why?
Lung
1
1990
3673
0.000
Why?
Tentler's Networks
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