Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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John Arcaroli

Concepts (369)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Colorectal Neoplasms
19
2018
866
2.320
Why?
Xenograft Model Antitumor Assays
21
2024
929
1.380
Why?
Antineoplastic Agents
17
2018
2207
1.280
Why?
Drug Resistance, Neoplasm
7
2016
881
0.960
Why?
Quinazolines
4
2012
266
0.950
Why?
Benzodioxoles
3
2012
161
0.910
Why?
Camptothecin
4
2016
138
0.840
Why?
Receptor, Notch1
3
2015
63
0.820
Why?
Aldehyde Dehydrogenase
6
2017
99
0.810
Why?
Mice, Nude
16
2024
678
0.770
Why?
Haplotypes
4
2012
498
0.710
Why?
Phosphatidylinositol 3-Kinases
10
2018
380
0.670
Why?
Gene Dosage
3
2015
148
0.600
Why?
Wnt Signaling Pathway
5
2024
210
0.600
Why?
Neutrophils
13
2007
1124
0.580
Why?
src-Family Kinases
3
2017
92
0.560
Why?
Amyloid Precursor Protein Secretases
3
2014
78
0.560
Why?
Endotoxemia
9
2004
86
0.550
Why?
Pancreatic Neoplasms
6
2024
928
0.550
Why?
Anilides
2
2018
84
0.550
Why?
Enzyme Inhibitors
5
2016
821
0.540
Why?
Protein Kinase Inhibitors
9
2018
980
0.520
Why?
Biomarkers, Tumor
9
2018
1321
0.510
Why?
Mice
41
2024
18338
0.490
Why?
Acute Lung Injury
2
2011
301
0.490
Why?
Receptors, Notch
2
2015
91
0.480
Why?
Tankyrases
1
2016
13
0.480
Why?
Cell Line, Tumor
21
2024
3537
0.460
Why?
Pyridines
4
2018
607
0.460
Why?
Drug Discovery
1
2016
154
0.450
Why?
Polymorphism, Genetic
3
2007
616
0.450
Why?
NF-kappa B
13
2007
660
0.440
Why?
3' Untranslated Regions
2
2012
150
0.430
Why?
DNA Copy Number Variations
1
2015
184
0.420
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2014
86
0.420
Why?
Proto-Oncogene Proteins c-met
1
2014
76
0.410
Why?
Tetrahydronaphthalenes
1
2013
31
0.390
Why?
Valine
1
2013
82
0.380
Why?
Mitogen-Activated Protein Kinases
7
2014
287
0.370
Why?
Animals
44
2024
38141
0.370
Why?
Lipopolysaccharides
9
2007
855
0.340
Why?
Signal Transduction
17
2018
5202
0.330
Why?
Sepsis
3
2007
661
0.330
Why?
Superoxide Dismutase
3
2008
303
0.320
Why?
Proto-Oncogene Proteins
8
2018
620
0.320
Why?
Urokinase-Type Plasminogen Activator
2
2007
25
0.320
Why?
Cell Proliferation
13
2024
2499
0.310
Why?
Interleukins
1
2011
249
0.300
Why?
Neoplasm Metastasis
4
2016
691
0.290
Why?
Hemorrhage
6
2004
826
0.280
Why?
Class I Phosphatidylinositol 3-Kinases
3
2014
108
0.280
Why?
Heterografts
3
2018
143
0.270
Why?
Apoptosis
11
2018
2411
0.270
Why?
HCT116 Cells
4
2018
78
0.270
Why?
SOXB1 Transcription Factors
2
2018
67
0.250
Why?
Carcinoma, Pancreatic Ductal
2
2024
294
0.250
Why?
Azepines
2
2018
106
0.240
Why?
Promoter Regions, Genetic
1
2011
1247
0.240
Why?
Benzimidazoles
3
2013
187
0.240
Why?
Mutation
3
2012
4093
0.240
Why?
Immunoblotting
5
2015
294
0.240
Why?
Receptors, Interleukin-1
1
2006
211
0.220
Why?
Neutrophil Activation
5
2003
84
0.220
Why?
beta Catenin
3
2016
253
0.220
Why?
Oligonucleotide Array Sequence Analysis
6
2015
751
0.210
Why?
Humans
46
2024
145491
0.210
Why?
TOR Serine-Threonine Kinases
4
2018
452
0.210
Why?
Pyrimidines
2
2018
520
0.200
Why?
Intracellular Signaling Peptides and Proteins
2
2006
456
0.200
Why?
Mice, Inbred BALB C
10
2003
1261
0.200
Why?
Adrenergic alpha-Antagonists
2
2002
34
0.200
Why?
Proto-Oncogene Proteins c-akt
8
2018
436
0.200
Why?
Colonic Neoplasms
2
2016
257
0.190
Why?
Adrenergic alpha-Agonists
1
2002
28
0.190
Why?
Proto-Oncogene Proteins c-raf
1
2002
45
0.190
Why?
Genetic Predisposition to Disease
1
2011
2355
0.180
Why?
Neuroimmunomodulation
1
2002
68
0.180
Why?
Adrenergic beta-Agonists
1
2002
93
0.180
Why?
ras Proteins
3
2013
151
0.180
Why?
Female
24
2018
78763
0.180
Why?
Adrenergic beta-Antagonists
2
2002
252
0.170
Why?
Aged
11
2016
26125
0.170
Why?
Middle Aged
12
2016
36176
0.160
Why?
Hemoptysis
1
2000
35
0.160
Why?
Polymorphism, Single Nucleotide
4
2011
2146
0.160
Why?
In Situ Hybridization, Fluorescence
2
2012
324
0.160
Why?
Cytokines
4
2005
2054
0.150
Why?
Carcinoma, Squamous Cell
2
2016
644
0.150
Why?
Head and Neck Neoplasms
2
2016
562
0.150
Why?
Cell Transformation, Neoplastic
2
2018
337
0.150
Why?
Adult
11
2016
40707
0.140
Why?
DNA Topoisomerases, Type II
2
2016
47
0.140
Why?
Transplantation, Heterologous
2
2016
169
0.140
Why?
CDC2 Protein Kinase
1
2018
27
0.140
Why?
Male
24
2016
72817
0.140
Why?
MAP Kinase Kinase Kinases
2
2015
70
0.140
Why?
Cyclic AMP Response Element-Binding Protein
4
2003
145
0.130
Why?
Oncogene Proteins v-abl
1
2017
5
0.130
Why?
Mitogen-Activated Protein Kinase Kinases
3
2010
126
0.130
Why?
Immunohistochemistry
5
2017
1710
0.130
Why?
p38 Mitogen-Activated Protein Kinases
6
2007
265
0.130
Why?
Proto-Oncogene Proteins p21(ras)
5
2016
254
0.130
Why?
Dasatinib
1
2017
57
0.130
Why?
Gene Expression Profiling
4
2018
1769
0.130
Why?
Case-Control Studies
3
2011
3619
0.130
Why?
Antigens, Neoplasm
2
2016
272
0.130
Why?
Neovascularization, Pathologic
2
2018
284
0.120
Why?
Intercellular Signaling Peptides and Proteins
2
2015
376
0.120
Why?
Angiogenesis Inhibitors
2
2018
238
0.120
Why?
Phosphatidylinositol 3-Kinase
1
2016
24
0.120
Why?
Receptors, Cell Surface
2
2012
372
0.120
Why?
Axin Protein
1
2016
18
0.120
Why?
Adenocarcinoma
2
2014
923
0.120
Why?
Corynebacterium
1
2017
49
0.120
Why?
Aurora Kinase A
1
2016
61
0.120
Why?
Corynebacterium Infections
1
2017
42
0.120
Why?
Neoplasms, Experimental
1
2017
168
0.120
Why?
Transcription Factor 7-Like 2 Protein
1
2016
26
0.120
Why?
Cell Cycle
5
2018
595
0.120
Why?
Neoplastic Stem Cells
2
2018
409
0.120
Why?
Autophagy
1
2018
288
0.120
Why?
Serrate-Jagged Proteins
1
2015
27
0.110
Why?
Genotype
3
2012
1853
0.110
Why?
Jagged-1 Protein
1
2015
22
0.110
Why?
RNA, Small Interfering
2
2015
632
0.110
Why?
Drug Synergism
2
2014
353
0.110
Why?
Gene Duplication
1
2015
69
0.110
Why?
Retinaldehyde
1
2015
4
0.110
Why?
RNA, Messenger
5
2016
2820
0.110
Why?
HMGB1 Protein
2
2007
51
0.110
Why?
Acetaldehyde
1
2015
17
0.110
Why?
Chemokines
5
2003
218
0.110
Why?
Neoplasms
3
2016
2897
0.110
Why?
Aged, 80 and over
5
2014
8326
0.110
Why?
Pyrimidinones
1
2015
125
0.110
Why?
Acridines
1
2014
9
0.110
Why?
Neoplasm Transplantation
4
2016
246
0.110
Why?
Chemokine CXCL2
4
2001
41
0.110
Why?
Topoisomerase II Inhibitors
1
2014
26
0.110
Why?
Pyrazoles
1
2018
517
0.110
Why?
Antineoplastic Combined Chemotherapy Protocols
3
2014
1965
0.100
Why?
Wnt Proteins
1
2015
133
0.100
Why?
Benzazepines
1
2014
35
0.100
Why?
Calcium-Binding Proteins
1
2015
222
0.100
Why?
Gene Expression Regulation
2
2007
2594
0.100
Why?
Cell Cycle Proteins
1
2018
631
0.100
Why?
Pyridones
1
2015
208
0.100
Why?
Respiration, Artificial
2
2011
712
0.100
Why?
Cell Growth Processes
1
2013
47
0.100
Why?
Insulin-Like Growth Factor Binding Protein 2
1
2012
8
0.090
Why?
Enzyme Activation
6
2003
762
0.090
Why?
Tumor Suppressor Proteins
1
2015
320
0.090
Why?
Cellular Senescence
1
2015
225
0.090
Why?
Random Allocation
1
2013
366
0.090
Why?
DNA-Binding Proteins
3
2016
1487
0.090
Why?
Gene Knockdown Techniques
1
2013
335
0.090
Why?
Disease Models, Animal
4
2018
4559
0.090
Why?
Aldehyde Dehydrogenase, Mitochondrial
3
2017
23
0.090
Why?
Molecular Targeted Therapy
1
2015
439
0.090
Why?
Chemokine CXCL12
1
2012
86
0.090
Why?
Cyclosporine
1
2013
256
0.090
Why?
Receptors, CXCR4
1
2012
91
0.090
Why?
Linkage Disequilibrium
2
2012
249
0.090
Why?
Immunoprecipitation
1
2012
147
0.090
Why?
Melanoma
1
2018
759
0.090
Why?
Hydroxamic Acids
1
2011
94
0.090
Why?
Lung Diseases
3
2004
783
0.090
Why?
Lung
8
2004
4103
0.080
Why?
Genetic Markers
1
2012
334
0.080
Why?
Peroxidase
2
2002
168
0.080
Why?
Prognosis
3
2015
4323
0.080
Why?
Drug Design
1
2012
176
0.080
Why?
PTEN Phosphohydrolase
1
2012
164
0.080
Why?
Sirolimus
1
2012
280
0.080
Why?
Genetic Association Studies
1
2012
369
0.080
Why?
Histone Deacetylase Inhibitors
1
2011
218
0.080
Why?
Antibodies, Monoclonal, Humanized
2
2013
994
0.080
Why?
Phosphorylation
3
2018
1707
0.080
Why?
Tumor Necrosis Factor-alpha
4
2004
1212
0.080
Why?
Administration, Oral
1
2012
863
0.080
Why?
Cetuximab
3
2016
111
0.070
Why?
Cell Separation
1
2010
304
0.070
Why?
Membrane Proteins
1
2015
1164
0.070
Why?
G2 Phase Cell Cycle Checkpoints
2
2018
44
0.070
Why?
Gene Expression Regulation, Neoplastic
4
2016
1439
0.070
Why?
Antibodies, Monoclonal
1
2015
1511
0.070
Why?
Models, Statistical
1
2012
679
0.070
Why?
Genetic Variation
2
2012
988
0.060
Why?
Cells, Cultured
6
2007
4127
0.060
Why?
Gene Expression
2
2003
1478
0.060
Why?
HT29 Cells
2
2018
37
0.060
Why?
Europe
1
2007
421
0.060
Why?
ErbB Receptors
3
2016
635
0.060
Why?
Flow Cytometry
1
2010
1156
0.060
Why?
Thymine
1
2006
16
0.060
Why?
Genome, Human
1
2008
420
0.060
Why?
Clinical Trials as Topic
2
2015
1058
0.060
Why?
Cytosine
1
2006
49
0.060
Why?
Interleukin-1 Receptor-Associated Kinases
1
2006
40
0.060
Why?
Phentolamine
2
2002
19
0.060
Why?
Inflammation Mediators
2
2006
505
0.060
Why?
MicroRNAs
1
2012
689
0.060
Why?
Homozygote
1
2006
200
0.060
Why?
MAP Kinase Kinase 2
2
2002
28
0.060
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2007
975
0.060
Why?
Tumor Burden
2
2018
324
0.060
Why?
Translocation, Genetic
1
2006
119
0.060
Why?
Propranolol
2
2002
44
0.060
Why?
MAP Kinase Kinase 1
2
2002
70
0.060
Why?
Survival Analysis
1
2008
1374
0.060
Why?
Spheroids, Cellular
2
2016
74
0.060
Why?
Cell Nucleus
2
2006
593
0.060
Why?
Mitogen-Activated Protein Kinase 3
2
2002
135
0.050
Why?
Introns
1
2006
256
0.050
Why?
Adolescent
3
2011
22485
0.050
Why?
Heat-Shock Proteins
1
2005
134
0.050
Why?
Models, Biological
2
2018
1815
0.050
Why?
Exons
1
2006
363
0.050
Why?
Neoplasm Invasiveness
2
2016
505
0.050
Why?
Bone Marrow Cells
2
2003
321
0.050
Why?
Shock, Septic
1
2006
226
0.050
Why?
Cause of Death
1
2006
469
0.050
Why?
Positron-Emission Tomography
2
2018
343
0.050
Why?
Oxidants
1
2003
103
0.050
Why?
Models, Genetic
1
2005
531
0.050
Why?
Paclitaxel
1
2024
256
0.050
Why?
Ribosomal Protein S6 Kinases
1
2002
26
0.050
Why?
Brimonidine Tartrate
1
2002
10
0.050
Why?
Deoxycytidine
1
2024
222
0.050
Why?
Phenylephrine
1
2002
74
0.050
Why?
RNA Interference
2
2016
473
0.050
Why?
Protein-Tyrosine Kinases
2
2002
431
0.040
Why?
Isoenzymes
1
2003
297
0.040
Why?
Quinoxalines
1
2002
64
0.040
Why?
Organoids
1
2024
144
0.040
Why?
Hydrogen Peroxide
1
2003
338
0.040
Why?
Transcription, Genetic
2
2006
1468
0.040
Why?
Cyclic AMP-Dependent Protein Kinases
1
2002
125
0.040
Why?
Lung Neoplasms
1
2015
2664
0.040
Why?
Free Radical Scavengers
1
2001
82
0.040
Why?
Membrane Glycoproteins
1
2004
496
0.040
Why?
Neoplasm Proteins
3
2016
441
0.040
Why?
MAP Kinase Signaling System
1
2002
306
0.040
Why?
High Mobility Group Proteins
1
2000
45
0.040
Why?
Imidazoles
1
2001
246
0.040
Why?
Interleukin-1
2
2000
961
0.040
Why?
Neutropenia
1
2000
155
0.040
Why?
Protein Processing, Post-Translational
1
2002
468
0.040
Why?
Nuclear Proteins
2
2001
743
0.040
Why?
Transcriptome
2
2016
1038
0.040
Why?
Adjuvants, Immunologic
1
2000
246
0.040
Why?
Trans-Activators
1
2001
397
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
23
0.040
Why?
Colorado
1
2008
4572
0.030
Why?
4-Aminobenzoic Acid
1
2018
8
0.030
Why?
Up-Regulation
2
2016
848
0.030
Why?
Biomarkers
1
2008
4283
0.030
Why?
Protein Transport
1
2018
438
0.030
Why?
Pneumonia
1
2003
632
0.030
Why?
Retinal Dehydrogenase
1
2016
29
0.030
Why?
Inhibitory Concentration 50
1
2016
90
0.030
Why?
Blotting, Western
2
2013
1162
0.030
Why?
Hyaluronan Receptors
1
2016
105
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
106
0.030
Why?
Tissue Array Analysis
1
2016
49
0.030
Why?
Protein Interaction Maps
1
2016
53
0.030
Why?
Papillomaviridae
1
2016
116
0.030
Why?
Drug Screening Assays, Antitumor
1
2016
191
0.030
Why?
Chromatin Immunoprecipitation
1
2016
139
0.030
Why?
Mice, Inbred C57BL
4
2015
5989
0.030
Why?
S-Phase Kinase-Associated Proteins
1
2015
20
0.030
Why?
Diphenylamine
1
2014
8
0.030
Why?
Prospective Studies
1
2007
8039
0.030
Why?
Cadherins
1
2016
200
0.030
Why?
Iloprost
1
2015
45
0.030
Why?
Acid Phosphatase
1
2014
14
0.030
Why?
Cell Division
1
2016
753
0.030
Why?
Tumor Cells, Cultured
1
2016
883
0.030
Why?
Gene Expression Regulation, Enzymologic
1
2016
268
0.030
Why?
Rhodamines
1
2014
21
0.030
Why?
G2 Phase
1
2014
39
0.030
Why?
Epithelial-Mesenchymal Transition
1
2016
211
0.030
Why?
Young Adult
1
2011
14192
0.030
Why?
Sequence Analysis, RNA
1
2016
443
0.030
Why?
Inflammation
1
2005
2883
0.030
Why?
Tretinoin
1
2015
125
0.030
Why?
Benzamides
1
2014
224
0.020
Why?
Transfection
1
2016
925
0.020
Why?
Receptor, Notch2
1
2013
15
0.020
Why?
Gonanes
1
2013
23
0.020
Why?
Antigens, CD
1
2016
557
0.020
Why?
Alphapapillomavirus
1
2013
35
0.020
Why?
Retrospective Studies
1
2011
17269
0.020
Why?
Receptors, CXCR
1
2012
5
0.020
Why?
Fluorocarbons
1
2014
119
0.020
Why?
Myeloid Cell Leukemia Sequence 1 Protein
2
2003
39
0.020
Why?
Erlotinib Hydrochloride
1
2012
72
0.020
Why?
Cyclin D1
1
2012
63
0.020
Why?
Tumor Suppressor Protein p53
1
2016
536
0.020
Why?
Active Transport, Cell Nucleus
2
2003
120
0.020
Why?
Protein Binding
1
2018
2250
0.020
Why?
Mice, Inbred C3H
2
2004
254
0.020
Why?
Computers
1
2012
67
0.020
Why?
Disease-Free Survival
1
2014
771
0.020
Why?
Maximum Tolerated Dose
1
2012
211
0.020
Why?
Niacinamide
1
2012
87
0.020
Why?
Tissue Distribution
1
2012
335
0.020
Why?
Phenylurea Compounds
1
2012
119
0.020
Why?
Injections, Intraperitoneal
2
2001
115
0.020
Why?
Calcium Signaling
1
2013
244
0.020
Why?
Mice, Knockout
3
2003
3125
0.020
Why?
Proto-Oncogene Proteins c-bcl-2
2
2003
238
0.020
Why?
Xanthine Oxidase
2
2001
79
0.020
Why?
Proto-Oncogene Proteins c-myc
1
2012
167
0.020
Why?
Acute Disease
2
2004
1040
0.020
Why?
Cluster Analysis
1
2011
517
0.020
Why?
United States
1
2007
16115
0.020
Why?
Ligands
1
2011
667
0.020
Why?
Vascular Endothelial Growth Factor A
1
2012
550
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
346
0.020
Why?
Models, Molecular
1
2014
1614
0.020
Why?
Survival Rate
1
2014
2093
0.020
Why?
Computational Biology
1
2013
687
0.020
Why?
Tumor Microenvironment
1
2012
737
0.020
Why?
Dose-Response Relationship, Drug
1
2012
2030
0.020
Why?
Adiposity
1
2012
529
0.020
Why?
Mice, Transgenic
2
2003
2189
0.020
Why?
Cell Movement
1
2011
961
0.020
Why?
Calcium
1
2013
1190
0.020
Why?
Oxidative Stress
2
2003
1350
0.020
Why?
Magnetic Resonance Imaging
1
2018
3897
0.010
Why?
Neutrophil Infiltration
1
2004
104
0.010
Why?
Permeability
1
2004
169
0.010
Why?
Transcription Factor AP-1
1
2003
79
0.010
Why?
Phosphotransferases
1
2003
27
0.010
Why?
bcl-Associated Death Protein
1
2003
9
0.010
Why?
Class Ib Phosphatidylinositol 3-Kinase
1
2003
5
0.010
Why?
Aconitate Hydratase
1
2003
14
0.010
Why?
Toll-Like Receptors
1
2004
193
0.010
Why?
JNK Mitogen-Activated Protein Kinases
1
2003
153
0.010
Why?
Metalloporphyrins
1
2003
63
0.010
Why?
Mice, Mutant Strains
1
2003
302
0.010
Why?
Algorithms
1
2010
1855
0.010
Why?
Lipid Peroxidation
1
2003
163
0.010
Why?
Extracellular Space
1
2003
119
0.010
Why?
Reproducibility of Results
1
2010
3424
0.010
Why?
Replication Protein C
1
2001
4
0.010
Why?
Tumor Necrosis Factor alpha-Induced Protein 3
1
2001
12
0.010
Why?
bcl-X Protein
1
2001
45
0.010
Why?
Toll-Like Receptor 4
1
2004
278
0.010
Why?
Biological Transport
1
2003
422
0.010
Why?
Protein Kinases
1
2003
314
0.010
Why?
Cysteine Endopeptidases
1
2001
74
0.010
Why?
CREB-Binding Protein
1
2001
34
0.010
Why?
Transcription Factor RelA
1
2001
85
0.010
Why?
Tungsten
1
2001
30
0.010
Why?
Animal Feed
1
2001
55
0.010
Why?
Immune Sera
1
2000
77
0.010
Why?
Proto-Oncogene Proteins c-fos
1
2001
196
0.010
Why?
Mitogen-Activated Protein Kinase 1
1
2001
171
0.010
Why?
Organ Specificity
1
2000
312
0.010
Why?
Endotoxins
1
2000
218
0.010
Why?
Antioxidants
1
2003
549
0.010
Why?
Protein Biosynthesis
1
2001
455
0.010
Why?
Carrier Proteins
1
2003
733
0.010
Why?
Intubation, Intratracheal
1
2000
326
0.010
Why?
Peptides
1
2001
993
0.010
Why?
Proteins
1
2001
1020
0.010
Why?
Treatment Outcome
1
2010
11831
0.010
Why?
Arcaroli's Networks
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