Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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John Arcaroli

Concepts (368)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Colorectal Neoplasms
19
2018
792
2.480
Why?
Xenograft Model Antitumor Assays
21
2024
870
1.450
Why?
Antineoplastic Agents
17
2018
2152
1.330
Why?
Drug Resistance, Neoplasm
7
2016
801
1.030
Why?
Benzodioxoles
3
2012
116
0.990
Why?
Quinazolines
4
2012
249
0.990
Why?
Camptothecin
4
2016
122
0.870
Why?
Receptor, Notch1
3
2015
65
0.850
Why?
Aldehyde Dehydrogenase
6
2017
100
0.840
Why?
Mice, Nude
16
2024
688
0.790
Why?
Haplotypes
4
2012
497
0.740
Why?
Phosphatidylinositol 3-Kinases
10
2018
368
0.700
Why?
Gene Dosage
3
2015
141
0.620
Why?
Wnt Signaling Pathway
5
2024
197
0.620
Why?
Neutrophils
13
2007
1274
0.600
Why?
src-Family Kinases
3
2017
93
0.590
Why?
Amyloid Precursor Protein Secretases
3
2014
79
0.580
Why?
Pancreatic Neoplasms
6
2024
859
0.580
Why?
Endotoxemia
9
2004
87
0.570
Why?
Anilides
2
2018
70
0.570
Why?
Enzyme Inhibitors
5
2016
850
0.560
Why?
Protein Kinase Inhibitors
9
2018
907
0.560
Why?
Biomarkers, Tumor
9
2018
1229
0.540
Why?
Mice
41
2024
17828
0.520
Why?
Acute Lung Injury
2
2011
299
0.510
Why?
Pyridines
4
2018
494
0.500
Why?
Receptors, Notch
2
2015
87
0.490
Why?
Tankyrases
1
2016
13
0.490
Why?
Cell Line, Tumor
21
2024
3397
0.490
Why?
Drug Discovery
1
2016
144
0.470
Why?
Polymorphism, Genetic
3
2007
624
0.460
Why?
NF-kappa B
13
2007
678
0.450
Why?
3' Untranslated Regions
2
2012
145
0.450
Why?
DNA Copy Number Variations
1
2015
179
0.440
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2014
85
0.440
Why?
Proto-Oncogene Proteins c-met
1
2014
72
0.420
Why?
Tetrahydronaphthalenes
1
2013
30
0.410
Why?
Valine
1
2013
77
0.400
Why?
Animals
44
2024
37243
0.390
Why?
Mitogen-Activated Protein Kinases
7
2014
316
0.370
Why?
Lipopolysaccharides
9
2007
888
0.350
Why?
Sepsis
3
2007
611
0.350
Why?
Signal Transduction
17
2018
5092
0.350
Why?
Proto-Oncogene Proteins
8
2018
621
0.330
Why?
Superoxide Dismutase
3
2008
352
0.330
Why?
Urokinase-Type Plasminogen Activator
2
2007
29
0.330
Why?
Cell Proliferation
13
2024
2480
0.320
Why?
Interleukins
1
2011
248
0.310
Why?
Neoplasm Metastasis
4
2016
667
0.300
Why?
Hemorrhage
6
2004
747
0.300
Why?
Class I Phosphatidylinositol 3-Kinases
3
2014
97
0.290
Why?
Heterografts
3
2018
135
0.280
Why?
HCT116 Cells
4
2018
80
0.270
Why?
Apoptosis
11
2018
2551
0.270
Why?
SOXB1 Transcription Factors
2
2018
62
0.260
Why?
Carcinoma, Pancreatic Ductal
2
2024
267
0.260
Why?
Azepines
2
2018
97
0.260
Why?
Promoter Regions, Genetic
1
2011
1235
0.250
Why?
Benzimidazoles
3
2013
177
0.250
Why?
Mutation
3
2012
3984
0.250
Why?
Immunoblotting
5
2015
309
0.240
Why?
Receptors, Interleukin-1
1
2006
215
0.230
Why?
Neutrophil Activation
5
2003
85
0.230
Why?
beta Catenin
3
2016
253
0.230
Why?
Humans
46
2024
138972
0.220
Why?
Oligonucleotide Array Sequence Analysis
6
2015
761
0.220
Why?
TOR Serine-Threonine Kinases
4
2018
416
0.220
Why?
Pyrimidines
2
2018
472
0.210
Why?
Intracellular Signaling Peptides and Proteins
2
2006
464
0.200
Why?
Mice, Inbred BALB C
10
2003
1261
0.200
Why?
Adrenergic alpha-Antagonists
2
2002
34
0.200
Why?
Proto-Oncogene Proteins c-akt
8
2018
442
0.200
Why?
Colonic Neoplasms
2
2016
247
0.200
Why?
Proto-Oncogene Proteins c-raf
1
2002
44
0.190
Why?
Adrenergic alpha-Agonists
1
2002
28
0.190
Why?
Genetic Predisposition to Disease
1
2011
2362
0.190
Why?
Female
24
2018
74016
0.190
Why?
Neuroimmunomodulation
1
2002
66
0.190
Why?
ras Proteins
3
2013
148
0.190
Why?
Aged
11
2016
24172
0.190
Why?
Adrenergic beta-Agonists
1
2002
97
0.180
Why?
Adrenergic beta-Antagonists
2
2002
228
0.180
Why?
Middle Aged
12
2016
33782
0.170
Why?
Hemoptysis
1
2000
36
0.170
Why?
Polymorphism, Single Nucleotide
4
2011
2138
0.160
Why?
In Situ Hybridization, Fluorescence
2
2012
310
0.160
Why?
Head and Neck Neoplasms
2
2016
549
0.160
Why?
Carcinoma, Squamous Cell
2
2016
637
0.160
Why?
Cytokines
4
2005
2083
0.160
Why?
Adult
11
2016
38393
0.160
Why?
Male
24
2016
68250
0.150
Why?
Cell Transformation, Neoplastic
2
2018
333
0.150
Why?
DNA Topoisomerases, Type II
2
2016
44
0.150
Why?
Transplantation, Heterologous
2
2016
193
0.150
Why?
CDC2 Protein Kinase
1
2018
32
0.150
Why?
MAP Kinase Kinase Kinases
2
2015
72
0.140
Why?
Oncogene Proteins v-abl
1
2017
5
0.140
Why?
Cyclic AMP Response Element-Binding Protein
4
2003
145
0.140
Why?
Mitogen-Activated Protein Kinase Kinases
3
2010
132
0.140
Why?
p38 Mitogen-Activated Protein Kinases
6
2007
280
0.140
Why?
Dasatinib
1
2017
56
0.130
Why?
Proto-Oncogene Proteins p21(ras)
5
2016
262
0.130
Why?
Immunohistochemistry
5
2017
1730
0.130
Why?
Gene Expression Profiling
4
2018
1746
0.130
Why?
Case-Control Studies
3
2011
3574
0.130
Why?
Angiogenesis Inhibitors
2
2018
230
0.130
Why?
Neovascularization, Pathologic
2
2018
296
0.130
Why?
Intercellular Signaling Peptides and Proteins
2
2015
385
0.130
Why?
Phosphatidylinositol 3-Kinase
1
2016
26
0.130
Why?
Adenocarcinoma
2
2014
882
0.130
Why?
Receptors, Cell Surface
2
2012
394
0.130
Why?
Aurora Kinase A
1
2016
55
0.130
Why?
Axin Protein
1
2016
19
0.130
Why?
Corynebacterium
1
2017
49
0.120
Why?
Antigens, Neoplasm
2
2016
316
0.120
Why?
Corynebacterium Infections
1
2017
42
0.120
Why?
Cell Cycle
5
2018
593
0.120
Why?
Neoplasms, Experimental
1
2017
174
0.120
Why?
Transcription Factor 7-Like 2 Protein
1
2016
26
0.120
Why?
Neoplastic Stem Cells
2
2018
397
0.120
Why?
Autophagy
1
2018
286
0.120
Why?
Genotype
3
2012
1849
0.120
Why?
Serrate-Jagged Proteins
1
2015
27
0.120
Why?
Jagged-1 Protein
1
2015
23
0.120
Why?
RNA, Messenger
5
2016
2815
0.120
Why?
Neoplasms
3
2016
2687
0.120
Why?
RNA, Small Interfering
2
2015
626
0.120
Why?
Aged, 80 and over
5
2014
7685
0.120
Why?
Drug Synergism
2
2014
367
0.120
Why?
Gene Duplication
1
2015
65
0.120
Why?
Retinaldehyde
1
2015
4
0.110
Why?
HMGB1 Protein
2
2007
50
0.110
Why?
Pyrazoles
1
2018
425
0.110
Why?
Acetaldehyde
1
2015
17
0.110
Why?
Chemokines
5
2003
226
0.110
Why?
Pyrimidinones
1
2015
114
0.110
Why?
Acridines
1
2014
7
0.110
Why?
Neoplasm Transplantation
4
2016
249
0.110
Why?
Antineoplastic Combined Chemotherapy Protocols
3
2014
1742
0.110
Why?
Chemokine CXCL2
4
2001
42
0.110
Why?
Topoisomerase II Inhibitors
1
2014
26
0.110
Why?
Benzazepines
1
2014
35
0.110
Why?
Wnt Proteins
1
2015
135
0.110
Why?
Pyridones
1
2015
170
0.110
Why?
Respiration, Artificial
2
2011
670
0.110
Why?
Calcium-Binding Proteins
1
2015
215
0.110
Why?
Cell Cycle Proteins
1
2018
617
0.110
Why?
Gene Expression Regulation
2
2007
2591
0.100
Why?
Cell Growth Processes
1
2013
53
0.100
Why?
Cellular Senescence
1
2015
190
0.100
Why?
Insulin-Like Growth Factor Binding Protein 2
1
2012
8
0.100
Why?
Tumor Suppressor Proteins
1
2015
322
0.100
Why?
Disease Models, Animal
4
2018
4316
0.100
Why?
DNA-Binding Proteins
3
2016
1473
0.100
Why?
Random Allocation
1
2013
362
0.100
Why?
Enzyme Activation
6
2003
819
0.090
Why?
Aldehyde Dehydrogenase, Mitochondrial
3
2017
23
0.090
Why?
Gene Knockdown Techniques
1
2013
329
0.090
Why?
Molecular Targeted Therapy
1
2015
413
0.090
Why?
Chemokine CXCL12
1
2012
83
0.090
Why?
Receptors, CXCR4
1
2012
87
0.090
Why?
Cyclosporine
1
2013
266
0.090
Why?
Linkage Disequilibrium
2
2012
258
0.090
Why?
Immunoprecipitation
1
2012
155
0.090
Why?
Melanoma
1
2018
757
0.090
Why?
Lung Diseases
3
2004
782
0.090
Why?
Hydroxamic Acids
1
2011
90
0.090
Why?
Lung
8
2004
4103
0.090
Why?
Prognosis
3
2015
3995
0.090
Why?
Peroxidase
2
2002
182
0.090
Why?
Genetic Markers
1
2012
344
0.090
Why?
Drug Design
1
2012
165
0.090
Why?
PTEN Phosphohydrolase
1
2012
163
0.080
Why?
Sirolimus
1
2012
277
0.080
Why?
Antibodies, Monoclonal, Humanized
2
2013
814
0.080
Why?
Genetic Association Studies
1
2012
373
0.080
Why?
Histone Deacetylase Inhibitors
1
2011
209
0.080
Why?
Administration, Oral
1
2012
787
0.080
Why?
Phosphorylation
3
2018
1767
0.080
Why?
Cetuximab
3
2016
98
0.080
Why?
Tumor Necrosis Factor-alpha
4
2004
1244
0.080
Why?
Cell Separation
1
2010
317
0.080
Why?
Membrane Proteins
1
2015
1149
0.070
Why?
G2 Phase Cell Cycle Checkpoints
2
2018
44
0.070
Why?
Gene Expression Regulation, Neoplastic
4
2016
1395
0.070
Why?
Antibodies, Monoclonal
1
2015
1437
0.070
Why?
Models, Statistical
1
2012
665
0.070
Why?
Genetic Variation
2
2012
990
0.070
Why?
Cells, Cultured
6
2007
4182
0.060
Why?
HT29 Cells
2
2018
41
0.060
Why?
Gene Expression
2
2003
1487
0.060
Why?
Europe
1
2007
407
0.060
Why?
ErbB Receptors
3
2016
610
0.060
Why?
Clinical Trials as Topic
2
2015
1034
0.060
Why?
Flow Cytometry
1
2010
1192
0.060
Why?
Thymine
1
2006
15
0.060
Why?
Genome, Human
1
2008
418
0.060
Why?
Cytosine
1
2006
48
0.060
Why?
Interleukin-1 Receptor-Associated Kinases
1
2006
30
0.060
Why?
Phentolamine
2
2002
18
0.060
Why?
Tumor Burden
2
2018
307
0.060
Why?
Inflammation Mediators
2
2006
513
0.060
Why?
Homozygote
1
2006
202
0.060
Why?
MicroRNAs
1
2012
676
0.060
Why?
MAP Kinase Kinase 2
2
2002
28
0.060
Why?
Translocation, Genetic
1
2006
109
0.060
Why?
Propranolol
2
2002
45
0.060
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2007
984
0.060
Why?
Survival Analysis
1
2008
1311
0.060
Why?
MAP Kinase Kinase 1
2
2002
75
0.060
Why?
Adolescent
3
2011
21581
0.060
Why?
Spheroids, Cellular
2
2016
75
0.060
Why?
Cell Nucleus
2
2006
608
0.060
Why?
Models, Biological
2
2018
1810
0.060
Why?
Introns
1
2006
254
0.060
Why?
Mitogen-Activated Protein Kinase 3
2
2002
150
0.060
Why?
Heat-Shock Proteins
1
2005
142
0.060
Why?
Exons
1
2006
352
0.060
Why?
Neoplasm Invasiveness
2
2016
501
0.050
Why?
Bone Marrow Cells
2
2003
326
0.050
Why?
Positron-Emission Tomography
2
2018
304
0.050
Why?
Cause of Death
1
2006
433
0.050
Why?
Shock, Septic
1
2006
209
0.050
Why?
Oxidants
1
2003
112
0.050
Why?
Paclitaxel
1
2024
237
0.050
Why?
Deoxycytidine
1
2024
192
0.050
Why?
Ribosomal Protein S6 Kinases
1
2002
25
0.050
Why?
Organoids
1
2024
119
0.050
Why?
Brimonidine Tartrate
1
2002
10
0.050
Why?
Models, Genetic
1
2005
591
0.050
Why?
Phenylephrine
1
2002
75
0.050
Why?
RNA Interference
2
2016
468
0.050
Why?
Quinoxalines
1
2002
67
0.050
Why?
Isoenzymes
1
2003
304
0.050
Why?
Hydrogen Peroxide
1
2003
332
0.050
Why?
Protein-Tyrosine Kinases
2
2002
431
0.050
Why?
Transcription, Genetic
2
2006
1471
0.050
Why?
Cyclic AMP-Dependent Protein Kinases
1
2002
129
0.050
Why?
Lung Neoplasms
1
2015
2533
0.040
Why?
Membrane Glycoproteins
1
2004
501
0.040
Why?
Free Radical Scavengers
1
2001
87
0.040
Why?
Neoplasm Proteins
3
2016
433
0.040
Why?
High Mobility Group Proteins
1
2000
44
0.040
Why?
Imidazoles
1
2001
239
0.040
Why?
MAP Kinase Signaling System
1
2002
322
0.040
Why?
Neutropenia
1
2000
157
0.040
Why?
Interleukin-1
2
2000
966
0.040
Why?
Transcriptome
2
2016
966
0.040
Why?
Protein Processing, Post-Translational
1
2002
462
0.040
Why?
Nuclear Proteins
2
2001
707
0.040
Why?
Adjuvants, Immunologic
1
2000
237
0.040
Why?
Trans-Activators
1
2001
391
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
24
0.040
Why?
Colorado
1
2008
4543
0.040
Why?
4-Aminobenzoic Acid
1
2018
8
0.040
Why?
Up-Regulation
2
2016
852
0.030
Why?
Biomarkers
1
2008
4095
0.030
Why?
Protein Transport
1
2018
443
0.030
Why?
Pneumonia
1
2003
644
0.030
Why?
Retinal Dehydrogenase
1
2016
29
0.030
Why?
Inhibitory Concentration 50
1
2016
89
0.030
Why?
Hyaluronan Receptors
1
2016
102
0.030
Why?
Blotting, Western
2
2013
1232
0.030
Why?
Tissue Array Analysis
1
2016
51
0.030
Why?
Protein Interaction Maps
1
2016
50
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
122
0.030
Why?
Mice, Inbred C57BL
4
2015
5801
0.030
Why?
Drug Screening Assays, Antitumor
1
2016
193
0.030
Why?
Chromatin Immunoprecipitation
1
2016
136
0.030
Why?
Papillomaviridae
1
2016
132
0.030
Why?
Prospective Studies
1
2007
7661
0.030
Why?
S-Phase Kinase-Associated Proteins
1
2015
20
0.030
Why?
Diphenylamine
1
2014
9
0.030
Why?
Iloprost
1
2015
45
0.030
Why?
Cadherins
1
2016
203
0.030
Why?
Acid Phosphatase
1
2014
20
0.030
Why?
Rhodamines
1
2014
20
0.030
Why?
Gene Expression Regulation, Enzymologic
1
2016
276
0.030
Why?
Cell Division
1
2016
794
0.030
Why?
G2 Phase
1
2014
39
0.030
Why?
Tumor Cells, Cultured
1
2016
956
0.030
Why?
Young Adult
1
2011
13371
0.030
Why?
Inflammation
1
2005
2853
0.030
Why?
Epithelial-Mesenchymal Transition
1
2016
210
0.030
Why?
Tretinoin
1
2015
123
0.030
Why?
Sequence Analysis, RNA
1
2016
449
0.030
Why?
Benzamides
1
2014
213
0.030
Why?
Transfection
1
2016
942
0.030
Why?
Antigens, CD
1
2016
537
0.030
Why?
Receptor, Notch2
1
2013
15
0.030
Why?
Gonanes
1
2013
27
0.030
Why?
Retrospective Studies
1
2011
15901
0.030
Why?
Alphapapillomavirus
1
2013
39
0.020
Why?
Receptors, CXCR
1
2012
3
0.020
Why?
Erlotinib Hydrochloride
1
2012
69
0.020
Why?
Myeloid Cell Leukemia Sequence 1 Protein
2
2003
40
0.020
Why?
Cyclin D1
1
2012
68
0.020
Why?
Disease-Free Survival
1
2014
704
0.020
Why?
Protein Binding
1
2018
2233
0.020
Why?
Active Transport, Cell Nucleus
2
2003
121
0.020
Why?
Tumor Suppressor Protein p53
1
2016
527
0.020
Why?
Computers
1
2012
69
0.020
Why?
Mice, Inbred C3H
2
2004
270
0.020
Why?
Maximum Tolerated Dose
1
2012
204
0.020
Why?
Niacinamide
1
2012
82
0.020
Why?
Tissue Distribution
1
2012
330
0.020
Why?
Phenylurea Compounds
1
2012
95
0.020
Why?
Injections, Intraperitoneal
2
2001
114
0.020
Why?
Mice, Knockout
3
2003
3029
0.020
Why?
Calcium Signaling
1
2013
250
0.020
Why?
Proto-Oncogene Proteins c-bcl-2
2
2003
236
0.020
Why?
Proto-Oncogene Proteins c-myc
1
2012
147
0.020
Why?
Xanthine Oxidase
2
2001
81
0.020
Why?
Acute Disease
2
2004
993
0.020
Why?
Cluster Analysis
1
2011
517
0.020
Why?
United States
1
2007
15074
0.020
Why?
Ligands
1
2011
666
0.020
Why?
Vascular Endothelial Growth Factor A
1
2012
550
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
342
0.020
Why?
Survival Rate
1
2014
1934
0.020
Why?
Models, Molecular
1
2014
1597
0.020
Why?
Computational Biology
1
2013
650
0.020
Why?
Tumor Microenvironment
1
2012
668
0.020
Why?
Dose-Response Relationship, Drug
1
2012
2047
0.020
Why?
Adiposity
1
2012
522
0.020
Why?
Cell Movement
1
2011
969
0.020
Why?
Mice, Transgenic
2
2003
2171
0.020
Why?
Calcium
1
2013
1188
0.020
Why?
Oxidative Stress
2
2003
1318
0.020
Why?
Magnetic Resonance Imaging
1
2018
3636
0.020
Why?
Permeability
1
2004
161
0.010
Why?
Neutrophil Infiltration
1
2004
108
0.010
Why?
Transcription Factor AP-1
1
2003
88
0.010
Why?
Phosphotransferases
1
2003
24
0.010
Why?
Class Ib Phosphatidylinositol 3-Kinase
1
2003
3
0.010
Why?
bcl-Associated Death Protein
1
2003
9
0.010
Why?
Aconitate Hydratase
1
2003
17
0.010
Why?
Toll-Like Receptors
1
2004
189
0.010
Why?
JNK Mitogen-Activated Protein Kinases
1
2003
159
0.010
Why?
Algorithms
1
2010
1730
0.010
Why?
Lipid Peroxidation
1
2003
152
0.010
Why?
Reproducibility of Results
1
2010
3313
0.010
Why?
Mice, Mutant Strains
1
2003
309
0.010
Why?
Extracellular Space
1
2003
129
0.010
Why?
Metalloporphyrins
1
2003
105
0.010
Why?
Replication Protein C
1
2001
4
0.010
Why?
Tumor Necrosis Factor alpha-Induced Protein 3
1
2001
11
0.010
Why?
bcl-X Protein
1
2001
43
0.010
Why?
Biological Transport
1
2003
403
0.010
Why?
Toll-Like Receptor 4
1
2004
275
0.010
Why?
Cysteine Endopeptidases
1
2001
74
0.010
Why?
Protein Kinases
1
2003
308
0.010
Why?
CREB-Binding Protein
1
2001
33
0.010
Why?
Transcription Factor RelA
1
2001
85
0.010
Why?
Tungsten
1
2001
30
0.010
Why?
Animal Feed
1
2001
54
0.010
Why?
Immune Sera
1
2000
83
0.010
Why?
Proto-Oncogene Proteins c-fos
1
2001
191
0.010
Why?
Mitogen-Activated Protein Kinase 1
1
2001
183
0.010
Why?
Organ Specificity
1
2000
310
0.010
Why?
Endotoxins
1
2000
220
0.010
Why?
Protein Biosynthesis
1
2001
434
0.010
Why?
Antioxidants
1
2003
593
0.010
Why?
Carrier Proteins
1
2003
737
0.010
Why?
Intubation, Intratracheal
1
2000
279
0.010
Why?
Peptides
1
2001
980
0.010
Why?
Treatment Outcome
1
2010
10921
0.010
Why?
Proteins
1
2001
1009
0.010
Why?
Arcaroli's Networks
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