Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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John Arcaroli

Concepts (369)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Colorectal Neoplasms
19
2018
876
2.290
Why?
Xenograft Model Antitumor Assays
21
2024
939
1.370
Why?
Antineoplastic Agents
17
2018
2231
1.270
Why?
Drug Resistance, Neoplasm
7
2016
889
0.950
Why?
Quinazolines
4
2012
266
0.950
Why?
Benzodioxoles
3
2012
162
0.910
Why?
Camptothecin
4
2016
138
0.840
Why?
Receptor, Notch1
3
2015
63
0.810
Why?
Aldehyde Dehydrogenase
6
2017
99
0.810
Why?
Mice, Nude
16
2024
680
0.760
Why?
Haplotypes
4
2012
509
0.700
Why?
Phosphatidylinositol 3-Kinases
10
2018
383
0.670
Why?
Gene Dosage
3
2015
145
0.600
Why?
Wnt Signaling Pathway
5
2024
212
0.590
Why?
Neutrophils
13
2007
1135
0.580
Why?
src-Family Kinases
3
2017
93
0.560
Why?
Amyloid Precursor Protein Secretases
3
2014
78
0.560
Why?
Endotoxemia
9
2004
86
0.550
Why?
Anilides
2
2018
84
0.540
Why?
Pancreatic Neoplasms
6
2024
947
0.540
Why?
Enzyme Inhibitors
5
2016
822
0.540
Why?
Protein Kinase Inhibitors
9
2018
984
0.520
Why?
Biomarkers, Tumor
9
2018
1339
0.500
Why?
Mice
41
2024
18491
0.490
Why?
Acute Lung Injury
2
2011
312
0.480
Why?
Receptors, Notch
2
2015
91
0.470
Why?
Tankyrases
1
2016
13
0.470
Why?
Cell Line, Tumor
21
2024
3565
0.460
Why?
Pyridines
4
2018
610
0.460
Why?
Polymorphism, Genetic
3
2007
615
0.450
Why?
Drug Discovery
1
2016
153
0.450
Why?
NF-kappa B
13
2007
676
0.430
Why?
3' Untranslated Regions
2
2012
149
0.430
Why?
DNA Copy Number Variations
1
2015
190
0.420
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2014
87
0.420
Why?
Proto-Oncogene Proteins c-met
1
2014
76
0.400
Why?
Tetrahydronaphthalenes
1
2013
34
0.390
Why?
Valine
1
2013
83
0.380
Why?
Mitogen-Activated Protein Kinases
7
2014
288
0.360
Why?
Animals
44
2024
38410
0.360
Why?
Lipopolysaccharides
9
2007
863
0.340
Why?
Signal Transduction
17
2018
5272
0.330
Why?
Sepsis
3
2007
671
0.330
Why?
Superoxide Dismutase
3
2008
308
0.320
Why?
Proto-Oncogene Proteins
8
2018
627
0.320
Why?
Urokinase-Type Plasminogen Activator
2
2007
25
0.310
Why?
Cell Proliferation
13
2024
2529
0.300
Why?
Interleukins
1
2011
248
0.300
Why?
Neoplasm Metastasis
4
2016
695
0.290
Why?
Class I Phosphatidylinositol 3-Kinases
3
2014
108
0.270
Why?
Hemorrhage
6
2004
832
0.270
Why?
Heterografts
3
2018
143
0.270
Why?
Apoptosis
11
2018
2454
0.260
Why?
HCT116 Cells
4
2018
76
0.260
Why?
SOXB1 Transcription Factors
2
2018
67
0.250
Why?
Carcinoma, Pancreatic Ductal
2
2024
299
0.240
Why?
Azepines
2
2018
105
0.240
Why?
Promoter Regions, Genetic
1
2011
1253
0.240
Why?
Benzimidazoles
3
2013
190
0.240
Why?
Mutation
3
2012
4130
0.240
Why?
Immunoblotting
5
2015
296
0.240
Why?
Receptors, Interleukin-1
1
2006
211
0.220
Why?
Neutrophil Activation
5
2003
84
0.220
Why?
beta Catenin
3
2016
254
0.220
Why?
Oligonucleotide Array Sequence Analysis
6
2015
751
0.210
Why?
Humans
46
2024
147293
0.210
Why?
TOR Serine-Threonine Kinases
4
2018
456
0.210
Why?
Pyrimidines
2
2018
532
0.200
Why?
Intracellular Signaling Peptides and Proteins
2
2006
459
0.200
Why?
Mice, Inbred BALB C
10
2003
1266
0.200
Why?
Adrenergic alpha-Antagonists
2
2002
34
0.190
Why?
Proto-Oncogene Proteins c-akt
8
2018
440
0.190
Why?
Colonic Neoplasms
2
2016
258
0.190
Why?
Adrenergic alpha-Agonists
1
2002
28
0.190
Why?
Proto-Oncogene Proteins c-raf
1
2002
46
0.190
Why?
Neuroimmunomodulation
1
2002
67
0.180
Why?
Genetic Predisposition to Disease
1
2011
2458
0.180
Why?
Adrenergic beta-Agonists
1
2002
92
0.180
Why?
ras Proteins
3
2013
153
0.180
Why?
Female
24
2018
80076
0.170
Why?
Adrenergic beta-Antagonists
2
2002
252
0.170
Why?
Aged
11
2016
26514
0.170
Why?
Hemoptysis
1
2000
35
0.160
Why?
Middle Aged
12
2016
36821
0.160
Why?
Polymorphism, Single Nucleotide
4
2011
2223
0.160
Why?
In Situ Hybridization, Fluorescence
2
2012
330
0.150
Why?
Cytokines
4
2005
2086
0.150
Why?
Carcinoma, Squamous Cell
2
2016
648
0.150
Why?
Head and Neck Neoplasms
2
2016
569
0.150
Why?
Cell Transformation, Neoplastic
2
2018
340
0.140
Why?
DNA Topoisomerases, Type II
2
2016
42
0.140
Why?
Adult
11
2016
41405
0.140
Why?
Transplantation, Heterologous
2
2016
170
0.140
Why?
CDC2 Protein Kinase
1
2018
27
0.140
Why?
Male
24
2016
73950
0.140
Why?
MAP Kinase Kinase Kinases
2
2015
70
0.130
Why?
Cyclic AMP Response Element-Binding Protein
4
2003
146
0.130
Why?
Oncogene Proteins v-abl
1
2017
5
0.130
Why?
Mitogen-Activated Protein Kinase Kinases
3
2010
126
0.130
Why?
p38 Mitogen-Activated Protein Kinases
6
2007
264
0.130
Why?
Proto-Oncogene Proteins p21(ras)
5
2016
256
0.130
Why?
Immunohistochemistry
5
2017
1730
0.130
Why?
Dasatinib
1
2017
58
0.130
Why?
Gene Expression Profiling
4
2018
1794
0.130
Why?
Case-Control Studies
3
2011
3660
0.130
Why?
Antigens, Neoplasm
2
2016
273
0.130
Why?
Neovascularization, Pathologic
2
2018
287
0.120
Why?
Intercellular Signaling Peptides and Proteins
2
2015
376
0.120
Why?
Angiogenesis Inhibitors
2
2018
239
0.120
Why?
Phosphatidylinositol 3-Kinase
1
2016
25
0.120
Why?
Receptors, Cell Surface
2
2012
373
0.120
Why?
Axin Protein
1
2016
18
0.120
Why?
Corynebacterium
1
2017
50
0.120
Why?
Adenocarcinoma
2
2014
928
0.120
Why?
Aurora Kinase A
1
2016
61
0.120
Why?
Corynebacterium Infections
1
2017
43
0.120
Why?
Neoplasms, Experimental
1
2017
167
0.120
Why?
Transcription Factor 7-Like 2 Protein
1
2016
26
0.120
Why?
Neoplastic Stem Cells
2
2018
409
0.120
Why?
Cell Cycle
5
2018
600
0.120
Why?
Autophagy
1
2018
291
0.110
Why?
Serrate-Jagged Proteins
1
2015
27
0.110
Why?
Jagged-1 Protein
1
2015
22
0.110
Why?
Genotype
3
2012
1875
0.110
Why?
Drug Synergism
2
2014
355
0.110
Why?
RNA, Small Interfering
2
2015
643
0.110
Why?
Gene Duplication
1
2015
67
0.110
Why?
RNA, Messenger
5
2016
2812
0.110
Why?
Retinaldehyde
1
2015
4
0.110
Why?
HMGB1 Protein
2
2007
51
0.110
Why?
Acetaldehyde
1
2015
17
0.110
Why?
Chemokines
5
2003
217
0.110
Why?
Pyrimidinones
1
2015
125
0.110
Why?
Neoplasms
3
2016
2946
0.110
Why?
Aged, 80 and over
5
2014
8430
0.110
Why?
Acridines
1
2014
9
0.110
Why?
Neoplasm Transplantation
4
2016
246
0.110
Why?
Chemokine CXCL2
4
2001
41
0.110
Why?
Topoisomerase II Inhibitors
1
2014
24
0.110
Why?
Pyrazoles
1
2018
518
0.100
Why?
Wnt Proteins
1
2015
133
0.100
Why?
Benzazepines
1
2014
35
0.100
Why?
Calcium-Binding Proteins
1
2015
222
0.100
Why?
Antineoplastic Combined Chemotherapy Protocols
3
2014
2001
0.100
Why?
Gene Expression Regulation
2
2007
2625
0.100
Why?
Cell Cycle Proteins
1
2018
633
0.100
Why?
Pyridones
1
2015
210
0.100
Why?
Respiration, Artificial
2
2011
717
0.100
Why?
Cell Growth Processes
1
2013
48
0.100
Why?
Insulin-Like Growth Factor Binding Protein 2
1
2012
8
0.090
Why?
Enzyme Activation
6
2003
762
0.090
Why?
Tumor Suppressor Proteins
1
2015
323
0.090
Why?
Random Allocation
1
2013
366
0.090
Why?
DNA-Binding Proteins
3
2016
1488
0.090
Why?
Cellular Senescence
1
2015
229
0.090
Why?
Gene Knockdown Techniques
1
2013
334
0.090
Why?
Aldehyde Dehydrogenase, Mitochondrial
3
2017
23
0.090
Why?
Molecular Targeted Therapy
1
2015
444
0.090
Why?
Disease Models, Animal
4
2018
4604
0.090
Why?
Chemokine CXCL12
1
2012
86
0.090
Why?
Cyclosporine
1
2013
257
0.090
Why?
Receptors, CXCR4
1
2012
91
0.090
Why?
Linkage Disequilibrium
2
2012
259
0.090
Why?
Immunoprecipitation
1
2012
149
0.090
Why?
Melanoma
1
2018
774
0.090
Why?
Hydroxamic Acids
1
2011
95
0.090
Why?
Lung Diseases
3
2004
787
0.080
Why?
Lung
8
2004
4141
0.080
Why?
Peroxidase
2
2002
168
0.080
Why?
Genetic Markers
1
2012
338
0.080
Why?
Drug Design
1
2012
177
0.080
Why?
Prognosis
3
2015
4383
0.080
Why?
PTEN Phosphohydrolase
1
2012
165
0.080
Why?
Sirolimus
1
2012
283
0.080
Why?
Genetic Association Studies
1
2012
374
0.080
Why?
Histone Deacetylase Inhibitors
1
2011
219
0.080
Why?
Phosphorylation
3
2018
1721
0.080
Why?
Antibodies, Monoclonal, Humanized
2
2013
1005
0.080
Why?
Tumor Necrosis Factor-alpha
4
2004
1224
0.080
Why?
Administration, Oral
1
2012
874
0.080
Why?
Cetuximab
3
2016
111
0.070
Why?
Cell Separation
1
2010
306
0.070
Why?
Membrane Proteins
1
2015
1171
0.070
Why?
G2 Phase Cell Cycle Checkpoints
2
2018
44
0.070
Why?
Gene Expression Regulation, Neoplastic
4
2016
1457
0.070
Why?
Antibodies, Monoclonal
1
2015
1514
0.070
Why?
Models, Statistical
1
2012
677
0.070
Why?
Genetic Variation
2
2012
995
0.060
Why?
Gene Expression
2
2003
1481
0.060
Why?
Cells, Cultured
6
2007
4169
0.060
Why?
HT29 Cells
2
2018
37
0.060
Why?
Europe
1
2007
426
0.060
Why?
ErbB Receptors
3
2016
638
0.060
Why?
Flow Cytometry
1
2010
1172
0.060
Why?
Thymine
1
2006
16
0.060
Why?
Genome, Human
1
2008
426
0.060
Why?
Clinical Trials as Topic
2
2015
1072
0.060
Why?
Cytosine
1
2006
49
0.060
Why?
Interleukin-1 Receptor-Associated Kinases
1
2006
41
0.060
Why?
Phentolamine
2
2002
19
0.060
Why?
Inflammation Mediators
2
2006
507
0.060
Why?
MicroRNAs
1
2012
694
0.060
Why?
Homozygote
1
2006
199
0.060
Why?
MAP Kinase Kinase 2
2
2002
28
0.060
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2007
980
0.060
Why?
Tumor Burden
2
2018
327
0.060
Why?
Propranolol
2
2002
44
0.060
Why?
Translocation, Genetic
1
2006
126
0.060
Why?
MAP Kinase Kinase 1
2
2002
70
0.060
Why?
Survival Analysis
1
2008
1386
0.050
Why?
Cell Nucleus
2
2006
589
0.050
Why?
Models, Biological
2
2018
1772
0.050
Why?
Mitogen-Activated Protein Kinase 3
2
2002
136
0.050
Why?
Introns
1
2006
260
0.050
Why?
Spheroids, Cellular
2
2016
82
0.050
Why?
Heat-Shock Proteins
1
2005
140
0.050
Why?
Adolescent
3
2011
22825
0.050
Why?
Exons
1
2006
365
0.050
Why?
Bone Marrow Cells
2
2003
325
0.050
Why?
Neoplasm Invasiveness
2
2016
512
0.050
Why?
Positron-Emission Tomography
2
2018
344
0.050
Why?
Cause of Death
1
2006
475
0.050
Why?
Shock, Septic
1
2006
230
0.050
Why?
Oxidants
1
2003
99
0.050
Why?
Models, Genetic
1
2005
536
0.050
Why?
Paclitaxel
1
2024
261
0.050
Why?
Ribosomal Protein S6 Kinases
1
2002
26
0.050
Why?
Deoxycytidine
1
2024
220
0.050
Why?
Brimonidine Tartrate
1
2002
10
0.050
Why?
Phenylephrine
1
2002
74
0.050
Why?
RNA Interference
2
2016
477
0.050
Why?
Protein-Tyrosine Kinases
2
2002
432
0.040
Why?
Isoenzymes
1
2003
296
0.040
Why?
Quinoxalines
1
2002
65
0.040
Why?
Organoids
1
2024
146
0.040
Why?
Hydrogen Peroxide
1
2003
338
0.040
Why?
Transcription, Genetic
2
2006
1456
0.040
Why?
Cyclic AMP-Dependent Protein Kinases
1
2002
125
0.040
Why?
Lung Neoplasms
1
2015
2679
0.040
Why?
Free Radical Scavengers
1
2001
82
0.040
Why?
Membrane Glycoproteins
1
2004
499
0.040
Why?
Neoplasm Proteins
3
2016
445
0.040
Why?
High Mobility Group Proteins
1
2000
45
0.040
Why?
MAP Kinase Signaling System
1
2002
308
0.040
Why?
Imidazoles
1
2001
247
0.040
Why?
Interleukin-1
2
2000
961
0.040
Why?
Neutropenia
1
2000
154
0.040
Why?
Protein Processing, Post-Translational
1
2002
480
0.040
Why?
Nuclear Proteins
2
2001
745
0.040
Why?
Transcriptome
2
2016
1059
0.040
Why?
Adjuvants, Immunologic
1
2000
245
0.040
Why?
Trans-Activators
1
2001
398
0.040
Why?
M Phase Cell Cycle Checkpoints
1
2018
23
0.040
Why?
4-Aminobenzoic Acid
1
2018
8
0.030
Why?
Colorado
1
2008
4591
0.030
Why?
Up-Regulation
2
2016
848
0.030
Why?
Biomarkers
1
2008
4351
0.030
Why?
Protein Transport
1
2018
442
0.030
Why?
Pneumonia
1
2003
636
0.030
Why?
Retinal Dehydrogenase
1
2016
29
0.030
Why?
Inhibitory Concentration 50
1
2016
91
0.030
Why?
Blotting, Western
2
2013
1186
0.030
Why?
Hyaluronan Receptors
1
2016
105
0.030
Why?
Cyclin-Dependent Kinase Inhibitor p21
1
2016
106
0.030
Why?
Tissue Array Analysis
1
2016
49
0.030
Why?
Protein Interaction Maps
1
2016
52
0.030
Why?
Papillomaviridae
1
2016
116
0.030
Why?
Drug Screening Assays, Antitumor
1
2016
194
0.030
Why?
Chromatin Immunoprecipitation
1
2016
139
0.030
Why?
Mice, Inbred C57BL
4
2015
6041
0.030
Why?
S-Phase Kinase-Associated Proteins
1
2015
19
0.030
Why?
Diphenylamine
1
2014
7
0.030
Why?
Prospective Studies
1
2007
8164
0.030
Why?
Iloprost
1
2015
45
0.030
Why?
Cadherins
1
2016
204
0.030
Why?
Acid Phosphatase
1
2014
15
0.030
Why?
Cell Division
1
2016
758
0.030
Why?
Tumor Cells, Cultured
1
2016
891
0.030
Why?
Gene Expression Regulation, Enzymologic
1
2016
269
0.030
Why?
Rhodamines
1
2014
20
0.030
Why?
G2 Phase
1
2014
39
0.030
Why?
Young Adult
1
2011
14437
0.030
Why?
Epithelial-Mesenchymal Transition
1
2016
222
0.030
Why?
Sequence Analysis, RNA
1
2016
443
0.030
Why?
Tretinoin
1
2015
125
0.030
Why?
Inflammation
1
2005
2920
0.030
Why?
Benzamides
1
2014
227
0.020
Why?
Transfection
1
2016
930
0.020
Why?
Receptor, Notch2
1
2013
15
0.020
Why?
Gonanes
1
2013
23
0.020
Why?
Antigens, CD
1
2016
562
0.020
Why?
Alphapapillomavirus
1
2013
35
0.020
Why?
Receptors, CXCR
1
2012
5
0.020
Why?
Retrospective Studies
1
2011
17560
0.020
Why?
Fluorocarbons
1
2014
122
0.020
Why?
Myeloid Cell Leukemia Sequence 1 Protein
2
2003
39
0.020
Why?
Erlotinib Hydrochloride
1
2012
72
0.020
Why?
Cyclin D1
1
2012
64
0.020
Why?
Tumor Suppressor Protein p53
1
2016
536
0.020
Why?
Protein Binding
1
2018
2249
0.020
Why?
Active Transport, Cell Nucleus
2
2003
117
0.020
Why?
Mice, Inbred C3H
2
2004
254
0.020
Why?
Computers
1
2012
66
0.020
Why?
Disease-Free Survival
1
2014
779
0.020
Why?
Maximum Tolerated Dose
1
2012
217
0.020
Why?
Tissue Distribution
1
2012
335
0.020
Why?
Phenylurea Compounds
1
2012
122
0.020
Why?
Injections, Intraperitoneal
2
2001
116
0.020
Why?
Niacinamide
1
2012
104
0.020
Why?
Calcium Signaling
1
2013
246
0.020
Why?
Mice, Knockout
3
2003
3153
0.020
Why?
Proto-Oncogene Proteins c-bcl-2
2
2003
241
0.020
Why?
Xanthine Oxidase
2
2001
79
0.020
Why?
Proto-Oncogene Proteins c-myc
1
2012
169
0.020
Why?
Acute Disease
2
2004
1049
0.020
Why?
Cluster Analysis
1
2011
502
0.020
Why?
United States
1
2007
16313
0.020
Why?
Vascular Endothelial Growth Factor A
1
2012
552
0.020
Why?
Ligands
1
2011
675
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2011
348
0.020
Why?
Models, Molecular
1
2014
1606
0.020
Why?
Survival Rate
1
2014
2110
0.020
Why?
Computational Biology
1
2013
677
0.020
Why?
Dose-Response Relationship, Drug
1
2012
2030
0.020
Why?
Tumor Microenvironment
1
2012
748
0.020
Why?
Adiposity
1
2012
533
0.020
Why?
Mice, Transgenic
2
2003
2197
0.020
Why?
Cell Movement
1
2011
966
0.020
Why?
Calcium
1
2013
1197
0.020
Why?
Oxidative Stress
2
2003
1368
0.010
Why?
Magnetic Resonance Imaging
1
2018
3980
0.010
Why?
Neutrophil Infiltration
1
2004
107
0.010
Why?
Permeability
1
2004
170
0.010
Why?
Transcription Factor AP-1
1
2003
79
0.010
Why?
Phosphotransferases
1
2003
26
0.010
Why?
bcl-Associated Death Protein
1
2003
10
0.010
Why?
Class Ib Phosphatidylinositol 3-Kinase
1
2003
5
0.010
Why?
Aconitate Hydratase
1
2003
14
0.010
Why?
JNK Mitogen-Activated Protein Kinases
1
2003
153
0.010
Why?
Toll-Like Receptors
1
2004
193
0.010
Why?
Metalloporphyrins
1
2003
63
0.010
Why?
Mice, Mutant Strains
1
2003
303
0.010
Why?
Extracellular Space
1
2003
117
0.010
Why?
Algorithms
1
2010
1868
0.010
Why?
Lipid Peroxidation
1
2003
169
0.010
Why?
Reproducibility of Results
1
2010
3448
0.010
Why?
Replication Protein C
1
2001
4
0.010
Why?
Tumor Necrosis Factor alpha-Induced Protein 3
1
2001
12
0.010
Why?
Toll-Like Receptor 4
1
2004
277
0.010
Why?
bcl-X Protein
1
2001
45
0.010
Why?
Biological Transport
1
2003
425
0.010
Why?
Protein Kinases
1
2003
312
0.010
Why?
Cysteine Endopeptidases
1
2001
80
0.010
Why?
CREB-Binding Protein
1
2001
34
0.010
Why?
Tungsten
1
2001
30
0.010
Why?
Transcription Factor RelA
1
2001
93
0.010
Why?
Animal Feed
1
2001
50
0.010
Why?
Immune Sera
1
2000
77
0.010
Why?
Proto-Oncogene Proteins c-fos
1
2001
196
0.010
Why?
Mitogen-Activated Protein Kinase 1
1
2001
172
0.010
Why?
Organ Specificity
1
2000
310
0.010
Why?
Endotoxins
1
2000
217
0.010
Why?
Antioxidants
1
2003
550
0.010
Why?
Protein Biosynthesis
1
2001
452
0.010
Why?
Carrier Proteins
1
2003
731
0.010
Why?
Intubation, Intratracheal
1
2000
329
0.010
Why?
Peptides
1
2001
1003
0.010
Why?
Proteins
1
2001
1024
0.010
Why?
Treatment Outcome
1
2010
11947
0.010
Why?
Arcaroli's Networks
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