Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Charles Hoeffer

Concepts (325)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Muscle Proteins
5
2026
240
2.550
Why?
Intracellular Signaling Peptides and Proteins
6
2026
454
2.200
Why?
Long-Term Potentiation
10
2017
199
1.800
Why?
Proto-Oncogene Proteins c-akt
4
2025
435
1.780
Why?
Down Syndrome
5
2026
522
1.590
Why?
Neuronal Plasticity
12
2017
306
1.200
Why?
Brain
6
2026
2934
1.150
Why?
Protein Biosynthesis
5
2021
455
1.110
Why?
Astrocytes
3
2025
228
1.070
Why?
Sleep
3
2026
890
1.010
Why?
Hippocampus
11
2017
966
0.960
Why?
Tauopathies
4
2026
17
0.950
Why?
Behavior, Animal
9
2023
521
0.950
Why?
Neurons
11
2026
1639
0.940
Why?
Memory
6
2021
296
0.940
Why?
Nicotinic Agonists
2
2025
138
0.920
Why?
Nicotine
2
2025
334
0.840
Why?
Calcium-Binding Proteins
3
2022
222
0.830
Why?
Alzheimer Disease
4
2022
622
0.820
Why?
Epistasis, Genetic
2
2023
65
0.770
Why?
tau Proteins
5
2026
115
0.730
Why?
Mice
36
2026
18261
0.730
Why?
Chronobiology Disorders
1
2022
16
0.720
Why?
Amyotrophic Lateral Sclerosis
1
2023
99
0.720
Why?
Sleep Wake Disorders
1
2026
308
0.710
Why?
DNA-Binding Proteins
5
2023
1484
0.690
Why?
Animals
46
2026
37948
0.660
Why?
Mice, Knockout
17
2025
3109
0.660
Why?
Spatial Memory
1
2020
28
0.650
Why?
Dendritic Spines
2
2021
69
0.630
Why?
Anxiety
6
2026
1122
0.630
Why?
Mice, Transgenic
11
2026
2184
0.610
Why?
Extinction, Psychological
1
2020
91
0.600
Why?
Mice, Inbred C57BL
14
2026
5967
0.600
Why?
Interleukin-17
2
2017
118
0.590
Why?
Synapses
9
2017
437
0.590
Why?
Signal Transduction
11
2016
5185
0.570
Why?
Aging
2
2022
1938
0.550
Why?
TOR Serine-Threonine Kinases
6
2014
452
0.550
Why?
Disease Models, Animal
14
2026
4539
0.520
Why?
Basolateral Nuclear Complex
1
2017
11
0.510
Why?
Eukaryotic Initiation Factor-4E
2
2021
32
0.500
Why?
Memory, Long-Term
2
2020
12
0.500
Why?
Memory Consolidation
1
2017
14
0.500
Why?
Transcriptome
1
2023
1036
0.490
Why?
Fragile X Syndrome
3
2012
119
0.470
Why?
Nerve Degeneration
1
2015
48
0.460
Why?
Genome-Wide Association Study
4
2023
1374
0.450
Why?
Autism Spectrum Disorder
2
2017
410
0.430
Why?
Up-Regulation
2
2021
848
0.420
Why?
Gene Expression Regulation
6
2017
2591
0.420
Why?
Protein Synthesis Inhibitors
2
2012
48
0.420
Why?
Interneurons
2
2026
125
0.420
Why?
Sensory Gating
2
2013
44
0.400
Why?
Fluoxetine
1
2013
54
0.390
Why?
Eukaryotic Initiation Factor-4F
1
2012
3
0.380
Why?
GABAergic Neurons
1
2013
37
0.380
Why?
Gene Expression
1
2017
1476
0.370
Why?
Protein Phosphatase 1
2
2013
32
0.370
Why?
Receptors, Nicotinic
3
2025
328
0.350
Why?
Mental Disorders
1
2020
1154
0.340
Why?
Eukaryotic Initiation Factor-4G
1
2011
6
0.340
Why?
Mitochondria
2
2015
984
0.340
Why?
Corticosterone
1
2012
242
0.330
Why?
Phosphorylation
10
2026
1704
0.310
Why?
eIF-2 Kinase
2
2024
29
0.310
Why?
Wakefulness
2
2024
170
0.310
Why?
Adaptor Proteins, Signal Transducing
2
2012
426
0.300
Why?
Tacrolimus Binding Protein 1A
1
2008
10
0.290
Why?
Raptors
1
2008
5
0.290
Why?
Male
23
2026
72431
0.290
Why?
Motor Activity
3
2022
723
0.290
Why?
Feces
1
2012
513
0.280
Why?
Maze Learning
5
2014
105
0.270
Why?
Protein Isoforms
2
2020
396
0.260
Why?
Receptors, Metabotropic Glutamate
4
2014
37
0.260
Why?
Protein Kinases
2
2008
314
0.260
Why?
Circadian Rhythm
1
2012
510
0.260
Why?
Receptors, AMPA
3
2026
148
0.250
Why?
Memory Disorders
3
2015
196
0.250
Why?
Fear
3
2008
366
0.250
Why?
Nervous System Diseases
1
2009
285
0.240
Why?
Polymorphism, Single Nucleotide
4
2023
2137
0.240
Why?
RNA, Messenger
4
2017
2815
0.240
Why?
Analysis of Variance
4
2017
1301
0.240
Why?
KCNQ2 Potassium Channel
1
2025
15
0.230
Why?
4-Aminopyridine
1
2025
30
0.230
Why?
Potassium Channel Blockers
1
2025
47
0.230
Why?
Electroencephalography
2
2026
555
0.230
Why?
Protein Aggregation, Pathological
1
2025
21
0.230
Why?
Phenotype
5
2023
3147
0.220
Why?
Neocortex
1
2025
49
0.220
Why?
Hydrazones
2
2017
26
0.220
Why?
Glial Fibrillary Acidic Protein
1
2025
125
0.220
Why?
Anti-Anxiety Agents
2
2023
47
0.210
Why?
In Vitro Techniques
7
2014
1046
0.210
Why?
Nucleus Accumbens
1
2026
135
0.210
Why?
Drosophila melanogaster
2
2003
237
0.210
Why?
Thiazoles
2
2017
139
0.210
Why?
Cyclic GMP-Dependent Protein Kinase Type II
2
2014
2
0.200
Why?
Coculture Techniques
1
2024
245
0.200
Why?
Mutation
3
2016
4081
0.200
Why?
Diazepam
1
2023
33
0.200
Why?
Cyclic AMP Response Element-Binding Protein
3
2013
145
0.200
Why?
Gliosis
1
2023
29
0.190
Why?
Cells, Cultured
4
2025
4110
0.190
Why?
RNA, Double-Stranded
1
2023
56
0.190
Why?
Vesicular Transport Proteins
1
2003
85
0.190
Why?
Nerve Net
1
2025
284
0.180
Why?
Rats, Sprague-Dawley
4
2021
2521
0.180
Why?
Long-Term Synaptic Depression
3
2014
49
0.180
Why?
Suprachiasmatic Nucleus
1
2022
19
0.180
Why?
Sleep Deprivation
1
2024
206
0.180
Why?
Pyramidal Cells
2
2025
80
0.180
Why?
Neural Inhibition
2
2017
178
0.170
Why?
Multifactorial Inheritance
1
2023
190
0.170
Why?
Prefrontal Cortex
2
2017
331
0.170
Why?
Nerve Tissue Proteins
3
2024
590
0.170
Why?
Induced Pluripotent Stem Cells
1
2024
269
0.170
Why?
Cerebral Cortex
2
2016
470
0.170
Why?
Epilepsy
1
2025
386
0.160
Why?
Spatial Behavior
1
2020
24
0.160
Why?
Motor Neurons
1
2023
235
0.160
Why?
Gene Regulatory Networks
1
2023
319
0.160
Why?
Neurodegenerative Diseases
1
2022
150
0.160
Why?
Calcineurin
2
2013
105
0.160
Why?
Spinal Cord
1
2023
384
0.160
Why?
Female
12
2026
78304
0.160
Why?
Cell Nucleus
1
2003
592
0.150
Why?
Anxiety Disorders
1
2023
370
0.150
Why?
Calcium
1
2026
1182
0.150
Why?
Synaptic Transmission
2
2014
292
0.150
Why?
Rats
4
2021
5570
0.150
Why?
Behavior, Addictive
1
2020
87
0.150
Why?
Genetic Markers
1
2020
332
0.150
Why?
Amygdala
2
2011
198
0.150
Why?
Memory, Short-Term
2
2014
271
0.140
Why?
Electrocorticography
1
2018
20
0.130
Why?
Conditioning, Classical
2
2017
119
0.130
Why?
Artificial Intelligence
1
2022
381
0.130
Why?
Brain Waves
1
2018
45
0.130
Why?
Polyribosomes
1
2017
22
0.130
Why?
Models, Biological
3
2009
1811
0.120
Why?
Models, Animal
2
2017
393
0.120
Why?
Neurofibrillary Tangles
1
2016
13
0.120
Why?
Microscopy, Electron, Transmission
1
2017
154
0.120
Why?
Association Learning
1
2017
71
0.120
Why?
Cell Differentiation
1
2024
2037
0.120
Why?
CA1 Region, Hippocampal
2
2014
49
0.120
Why?
Humans
20
2026
144667
0.120
Why?
Transcription Factors
2
2022
1726
0.120
Why?
Dynamins
1
2015
36
0.120
Why?
Sex Characteristics
1
2020
776
0.110
Why?
Haloperidol
2
2014
33
0.110
Why?
Antipsychotic Agents
2
2014
214
0.110
Why?
Th17 Cells
1
2016
100
0.110
Why?
Maternal-Fetal Exchange
1
2016
169
0.110
Why?
Alcoholism
1
2021
813
0.110
Why?
Electric Stimulation
3
2014
277
0.110
Why?
Neuroimaging
1
2017
293
0.100
Why?
Social Behavior
1
2017
287
0.100
Why?
Cell Count
2
2013
320
0.100
Why?
Antibodies
1
2016
396
0.100
Why?
Pyridines
3
2013
603
0.100
Why?
GABA-A Receptor Agonists
1
2013
17
0.100
Why?
Excitatory Postsynaptic Potentials
2
2011
119
0.100
Why?
Smoking
1
2020
1467
0.100
Why?
Sterols
1
2012
20
0.090
Why?
Nitro Compounds
1
2012
8
0.090
Why?
gamma-Aminobutyric Acid
1
2014
194
0.090
Why?
Brain-Derived Neurotrophic Factor
1
2013
151
0.090
Why?
Multiprotein Complexes
1
2014
171
0.090
Why?
Image Processing, Computer-Assisted
1
2017
779
0.090
Why?
Gene Deletion
1
2013
392
0.090
Why?
Photoperiod
1
2012
55
0.090
Why?
Ribosomal Protein S6
1
2011
18
0.090
Why?
Dopamine
1
2014
291
0.090
Why?
Reaction Time
1
2013
438
0.090
Why?
Dopamine and cAMP-Regulated Phosphoprotein 32
1
2011
9
0.090
Why?
Amyloid beta-Peptides
2
2011
243
0.090
Why?
Motor Skills
1
2012
104
0.090
Why?
Sirolimus
2
2011
280
0.090
Why?
Primary Cell Culture
1
2012
172
0.090
Why?
Ribosomal Protein S6 Kinases, 70-kDa
2
2008
36
0.080
Why?
Oxidants
1
2011
103
0.080
Why?
Cyclic AMP-Dependent Protein Kinases
1
2011
125
0.080
Why?
Calcium-Calmodulin-Dependent Protein Kinase Type 2
2
2014
196
0.080
Why?
Genotype
2
2014
1847
0.080
Why?
Gene Expression Profiling
1
2017
1766
0.080
Why?
Superoxides
1
2011
199
0.080
Why?
Prenatal Exposure Delayed Effects
1
2016
641
0.070
Why?
Enzyme Inhibitors
2
2011
820
0.070
Why?
Oxidative Stress
1
2015
1338
0.070
Why?
Exploratory Behavior
1
2008
85
0.070
Why?
Peptide Elongation Factor 1
1
2008
10
0.070
Why?
Ribosomal Protein S6 Kinases
1
2008
26
0.070
Why?
Membrane Proteins
1
2014
1159
0.070
Why?
Dose-Response Relationship, Radiation
1
2007
140
0.070
Why?
Activating Transcription Factor 4
1
2007
22
0.060
Why?
In Situ Hybridization
1
2007
318
0.060
Why?
Eukaryotic Initiation Factor-2
1
2007
33
0.060
Why?
Space Perception
1
2008
82
0.060
Why?
Pregnancy
2
2017
7122
0.060
Why?
Eukaryotic Initiation Factors
2
2021
12
0.060
Why?
Granulomatous Disease, Chronic
1
2006
48
0.060
Why?
Neuromuscular Junction
2
2003
65
0.060
Why?
Sex Factors
1
2012
2104
0.060
Why?
Pair Bond
1
2026
20
0.060
Why?
Larva
2
2003
245
0.060
Why?
Infant, Newborn
1
2017
6399
0.060
Why?
Purkinje Cells
1
2026
65
0.060
Why?
Mitogen-Activated Protein Kinases
2
2003
287
0.050
Why?
Cohort Studies
1
2015
5957
0.050
Why?
Protein Binding
1
2011
2243
0.050
Why?
Sleep, REM
1
2024
44
0.050
Why?
Drosophila
1
2025
167
0.050
Why?
Electrodes
1
2024
112
0.050
Why?
Protein Domains
1
2026
313
0.050
Why?
Time Factors
2
2012
7140
0.050
Why?
Carrier Proteins
2
2010
733
0.050
Why?
N-Ethylmaleimide-Sensitive Proteins
1
2003
5
0.050
Why?
Calcium-Transporting ATPases
1
2003
33
0.050
Why?
Sarcoplasmic Reticulum Calcium-Transporting ATPases
1
2003
32
0.050
Why?
CCAAT-Enhancer-Binding Proteins
1
2003
37
0.050
Why?
Learning
1
2008
448
0.050
Why?
Body Temperature
1
2024
226
0.050
Why?
Cell Adhesion Molecules, Neuronal
1
2003
42
0.050
Why?
Active Transport, Cell Nucleus
1
2003
120
0.050
Why?
Mitogen-Activated Protein Kinase Kinases
1
2003
126
0.050
Why?
Blood-Brain Barrier
1
2024
155
0.050
Why?
Mice, Inbred Strains
1
2023
396
0.050
Why?
Paralysis
1
2003
68
0.050
Why?
Methoxyhydroxyphenylglycol
2
2014
13
0.050
Why?
Action Potentials
1
2025
502
0.050
Why?
Species Specificity
1
2023
573
0.050
Why?
Transcription Factor AP-1
1
2002
79
0.040
Why?
Drosophila Proteins
1
2003
213
0.040
Why?
Psychopathology
1
2021
55
0.040
Why?
Adult
2
2017
40489
0.040
Why?
Central Nervous System
1
2003
279
0.040
Why?
Lipopolysaccharides
1
2024
854
0.040
Why?
Bombyx
1
2000
7
0.040
Why?
Temperature
1
2003
680
0.040
Why?
Apolipoproteins
1
2000
38
0.040
Why?
Ultrasonography
1
2003
776
0.040
Why?
NADPH Oxidase 2
2
2011
32
0.040
Why?
Seizures
1
2003
477
0.040
Why?
Child
2
2025
22600
0.040
Why?
Age of Onset
1
2020
551
0.030
Why?
NADPH Oxidases
2
2011
120
0.030
Why?
Prepulse Inhibition
1
2017
12
0.030
Why?
Gene Expression Regulation, Developmental
1
2002
906
0.030
Why?
Receptors, Adrenergic, beta-2
1
2017
36
0.030
Why?
Phosphatidylinositol 3-Kinases
2
2010
380
0.030
Why?
Child, Preschool
1
2012
11790
0.030
Why?
alpha7 Nicotinic Acetylcholine Receptor
1
2017
94
0.030
Why?
Reflex, Startle
1
2017
75
0.030
Why?
Nuclear Receptor Subfamily 1, Group F, Member 3
1
2016
14
0.030
Why?
Membrane Glycoproteins
2
2011
496
0.030
Why?
Antibodies, Blocking
1
2016
37
0.030
Why?
Fluorescent Antibody Technique
1
2017
364
0.030
Why?
Receptors, Retinoic Acid
1
2016
42
0.030
Why?
Behavioral Symptoms
1
2016
41
0.030
Why?
CRISPR-Cas Systems
1
2017
167
0.030
Why?
Young Adult
1
2012
14122
0.030
Why?
Tobacco Use Disorder
1
2017
218
0.030
Why?
Electrical Synapses
1
2014
6
0.030
Why?
Alcohol Drinking
1
2021
827
0.030
Why?
Biophysical Phenomena
1
2014
68
0.030
Why?
Mechanistic Target of Rapamycin Complex 1
1
2014
138
0.020
Why?
Rotarod Performance Test
1
2012
15
0.020
Why?
Microtubule-Associated Proteins
1
2014
195
0.020
Why?
Post-Synaptic Density
1
2012
12
0.020
Why?
Schizophrenia
1
2017
443
0.020
Why?
Cyclic GMP
1
2012
90
0.020
Why?
Adolescent
1
2012
22409
0.020
Why?
Aged
1
2012
25955
0.020
Why?
Gene Knock-In Techniques
1
2011
60
0.020
Why?
Emetine
1
2011
7
0.020
Why?
Onium Compounds
1
2011
8
0.020
Why?
Bicuculline
1
2011
18
0.020
Why?
GABA-A Receptor Antagonists
1
2011
19
0.020
Why?
rap GTP-Binding Proteins
1
2011
9
0.020
Why?
Ubiquinone
1
2011
35
0.020
Why?
Electrophysiological Phenomena
1
2011
59
0.020
Why?
Excitatory Amino Acid Antagonists
1
2011
107
0.020
Why?
Biphenyl Compounds
1
2011
66
0.020
Why?
Isoproterenol
1
2011
96
0.020
Why?
Adrenergic beta-Agonists
1
2011
92
0.020
Why?
Biophysics
1
2011
76
0.020
Why?
Flavonoids
1
2011
86
0.020
Why?
Organophosphorus Compounds
1
2011
84
0.020
Why?
Eukaryotic Initiation Factor-4A
1
2010
6
0.020
Why?
Patch-Clamp Techniques
1
2011
289
0.020
Why?
Oncogene Protein v-akt
1
2010
22
0.020
Why?
Colorado
1
2020
4558
0.020
Why?
Enzyme Activation
1
2011
762
0.020
Why?
Immunoprecipitation
1
2010
147
0.020
Why?
Middle Aged
1
2012
35971
0.020
Why?
Serine
1
2010
142
0.020
Why?
Superoxide Dismutase
1
2011
303
0.020
Why?
RNA 5' Terminal Oligopyrimidine Sequence
1
2008
1
0.020
Why?
Reactive Oxygen Species
1
2011
601
0.020
Why?
Phosphoproteins
1
2010
339
0.020
Why?
Autistic Disorder
1
2010
211
0.020
Why?
Antioxidants
1
2011
546
0.020
Why?
Extracellular Signal-Regulated MAP Kinases
1
2008
174
0.020
Why?
Dose-Response Relationship, Drug
1
2011
2019
0.020
Why?
Peptide Fragments
1
2010
691
0.020
Why?
Immunosuppressive Agents
1
2011
834
0.010
Why?
Conditioning, Operant
1
2006
98
0.010
Why?
Cell Cycle Proteins
1
2010
628
0.010
Why?
Cognition Disorders
1
2010
539
0.010
Why?
Taste
1
2008
240
0.010
Why?
Receptors, N-Methyl-D-Aspartate
1
2006
229
0.010
Why?
Proto-Oncogene Proteins c-jun
1
2002
54
0.010
Why?
Dimerization
1
2002
190
0.010
Why?
JNK Mitogen-Activated Protein Kinases
1
2002
153
0.010
Why?
Electrophysiology
1
2002
218
0.010
Why?
Cyclic AMP
1
2002
205
0.010
Why?
Proto-Oncogene Proteins c-fos
1
2002
194
0.010
Why?
DNA, Complementary
1
2000
273
0.010
Why?
Promoter Regions, Genetic
1
2002
1246
0.010
Why?
Amino Acid Sequence
1
2000
2136
0.010
Why?
Molecular Sequence Data
1
2000
2909
0.010
Why?
Hoeffer's Networks
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Physical Neighbors Expand Description
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