Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Philip Reigan

Concepts (387)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Thymidine Phosphorylase
7
2022
12
2.430
Why?
Antineoplastic Agents
16
2020
1875
2.100
Why?
Ribosomal Protein S6 Kinases, 90-kDa
4
2021
13
2.010
Why?
Protein Kinase Inhibitors
8
2021
784
1.890
Why?
Pyrimidines
6
2021
374
1.820
Why?
Protein-Tyrosine Kinases
6
2019
393
1.610
Why?
Nuclear Proteins
6
2018
591
1.460
Why?
Cell Cycle Proteins
5
2018
549
1.440
Why?
Enzyme Inhibitors
9
2021
743
1.290
Why?
Glioblastoma
3
2022
250
1.160
Why?
STAT3 Transcription Factor
3
2022
172
1.120
Why?
Pyrazoles
4
2018
361
1.010
Why?
Neoplasms
5
2023
2086
1.010
Why?
Models, Molecular
25
2021
1368
1.000
Why?
Pyrroles
2
2021
181
0.910
Why?
Prodrugs
4
2007
42
0.810
Why?
Pyrimidinones
4
2018
88
0.760
Why?
NAD(P)H Dehydrogenase (Quinone)
8
2011
31
0.760
Why?
Purines
1
2021
158
0.690
Why?
Pteridines
1
2020
20
0.680
Why?
Cell Survival
8
2022
1014
0.660
Why?
Drug Resistance, Neoplasm
4
2021
636
0.660
Why?
Structure-Activity Relationship
10
2020
499
0.650
Why?
Small Molecule Libraries
2
2016
79
0.640
Why?
AMP-Activated Protein Kinases
1
2020
170
0.630
Why?
Indolequinones
5
2011
5
0.620
Why?
Aldehydes
8
2014
138
0.580
Why?
Protein Binding
12
2021
1888
0.580
Why?
Brain Neoplasms
3
2020
966
0.580
Why?
HSP90 Heat-Shock Proteins
5
2011
43
0.580
Why?
Medulloblastoma
2
2016
172
0.550
Why?
Cell Line, Tumor
18
2022
2698
0.540
Why?
Glutamate-Cysteine Ligase
2
2013
14
0.530
Why?
Xanthine Oxidase
2
2007
71
0.520
Why?
Protein Isoforms
1
2017
337
0.510
Why?
Benzoquinones
4
2011
44
0.500
Why?
Uracil
3
2021
28
0.490
Why?
Cisplatin
1
2016
262
0.460
Why?
Isoxazoles
5
2023
51
0.460
Why?
Hydroquinones
3
2011
27
0.450
Why?
Lactams, Macrocyclic
3
2011
46
0.440
Why?
Deoxyribose
1
2013
5
0.440
Why?
Drug Screening Assays, Antitumor
5
2020
181
0.420
Why?
Glutathione
2
2011
293
0.420
Why?
Humans
57
2024
114043
0.380
Why?
Molecular Structure
5
2020
434
0.370
Why?
Molecular Docking Simulation
6
2023
101
0.360
Why?
Protein Conformation
4
2021
803
0.330
Why?
Catalytic Domain
5
2021
196
0.330
Why?
Cell Proliferation
10
2020
2173
0.330
Why?
Cell Line
5
2022
2629
0.330
Why?
Glucose
2
2013
899
0.320
Why?
Imidazoles
3
2021
203
0.310
Why?
Molecular Targeted Therapy
3
2016
347
0.310
Why?
Aldehyde Dehydrogenase
3
2014
102
0.310
Why?
Proto-Oncogene Proteins B-raf
2
2021
191
0.300
Why?
Signal Transduction
6
2022
4501
0.290
Why?
Amides
2
2020
87
0.290
Why?
Growth Inhibitors
1
2007
43
0.280
Why?
Pancreatic Neoplasms
4
2009
721
0.280
Why?
Proto-Oncogene Proteins c-akt
4
2013
397
0.270
Why?
Thyroid Neoplasms
2
2021
271
0.270
Why?
src Homology Domains
2
2016
33
0.260
Why?
Tumor Suppressor Protein p53
2
2023
445
0.250
Why?
Binding Sites
6
2018
1166
0.240
Why?
Molecular Dynamics Simulation
3
2023
200
0.240
Why?
Animals
27
2022
31565
0.240
Why?
Pyrrolidines
1
2004
55
0.230
Why?
G-Quadruplexes
2
2022
15
0.230
Why?
Giardia lamblia
1
2024
21
0.220
Why?
Thymidine
2
2022
58
0.210
Why?
DNA
3
2016
1350
0.210
Why?
Rifabutin
3
2008
5
0.210
Why?
Polycomb Repressive Complex 1
1
2023
38
0.210
Why?
Liver Diseases, Alcoholic
2
2014
81
0.200
Why?
Ear Diseases
1
2022
13
0.200
Why?
Amino Acid Transport System ASC
1
2022
10
0.200
Why?
K562 Cells
2
2020
73
0.200
Why?
Virus Internalization
1
2022
40
0.200
Why?
Models, Chemical
1
2023
248
0.190
Why?
Minor Histocompatibility Antigens
1
2022
41
0.190
Why?
Drug Synergism
3
2021
315
0.190
Why?
Catalysis
3
2013
289
0.190
Why?
Quinone Reductases
2
2011
15
0.190
Why?
Fluorouracil
1
2022
152
0.190
Why?
Proto-Oncogene Proteins c-myc
1
2022
116
0.180
Why?
Maneb
1
2020
7
0.180
Why?
Receptors, Androgen
1
2022
131
0.180
Why?
Heterocyclic Compounds
1
2020
18
0.180
Why?
Dose-Response Relationship, Drug
3
2020
1836
0.180
Why?
Mice
17
2022
14841
0.180
Why?
Mitogen-Activated Protein Kinase 3
1
2021
145
0.180
Why?
Lipoprotein Lipase
1
2020
54
0.180
Why?
Polymorphism, Genetic
2
2014
610
0.170
Why?
Mitogen-Activated Protein Kinase 1
1
2021
164
0.170
Why?
Neovascularization, Pathologic
1
2022
280
0.170
Why?
Fluorescence
1
2020
148
0.170
Why?
Amino Acid Sequence
8
2014
1981
0.160
Why?
Chromatography, High Pressure Liquid
5
2013
465
0.160
Why?
Adenocarcinoma, Follicular
1
2019
34
0.160
Why?
Thyroid Carcinoma, Anaplastic
1
2019
34
0.150
Why?
Protein Carbonylation
3
2013
51
0.150
Why?
Enzyme Assays
1
2018
21
0.150
Why?
Neoplastic Stem Cells
1
2022
327
0.150
Why?
CDC2 Protein Kinase
1
2018
25
0.150
Why?
Escherichia coli
4
2006
723
0.150
Why?
Receptors, Metabotropic Glutamate
1
2018
34
0.150
Why?
Pyridazines
1
2018
46
0.150
Why?
Phosphorylation
3
2018
1558
0.150
Why?
Proto-Oncogene Proteins p21(ras)
1
2019
228
0.150
Why?
Antigens, Neoplasm
2
2011
222
0.150
Why?
Glucocorticoids
1
2022
526
0.140
Why?
Leukemia, Myeloid, Acute
2
2022
533
0.140
Why?
Dihydropyridines
1
2017
15
0.140
Why?
Glycoproteins
2
2011
304
0.140
Why?
Oncogene Proteins, Fusion
1
2019
176
0.140
Why?
Cyclic S-Oxides
1
2016
1
0.140
Why?
Niclosamide
1
2016
1
0.140
Why?
Lysine
2
2023
241
0.140
Why?
Fluorescence Polarization
1
2016
35
0.140
Why?
MicroRNAs
1
2023
600
0.140
Why?
Antioxidants
2
2011
529
0.130
Why?
G2 Phase Cell Cycle Checkpoints
1
2016
41
0.130
Why?
M Phase Cell Cycle Checkpoints
1
2016
23
0.130
Why?
Antiviral Agents
1
2022
642
0.130
Why?
Immunity, Innate
1
2022
720
0.130
Why?
Parkinson Disease
1
2020
345
0.130
Why?
Molecular Sequence Data
7
2014
2783
0.130
Why?
Quantitative Structure-Activity Relationship
1
2015
13
0.130
Why?
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
2
2013
134
0.130
Why?
Oxidation-Reduction
5
2020
917
0.130
Why?
Crystallography, X-Ray
5
2017
402
0.130
Why?
Cells, Cultured
3
2020
3861
0.130
Why?
Alzheimer Disease
1
2020
442
0.120
Why?
Small-Conductance Calcium-Activated Potassium Channels
1
2015
8
0.120
Why?
Drug Design
1
2016
147
0.120
Why?
Membrane Proteins
2
2011
1016
0.120
Why?
HeLa Cells
1
2016
563
0.120
Why?
Retinaldehyde
1
2014
5
0.120
Why?
Allosteric Regulation
3
2023
81
0.120
Why?
Acetaldehyde
1
2014
15
0.120
Why?
Drug Discovery
1
2016
123
0.120
Why?
Recombinant Proteins
5
2011
1228
0.120
Why?
Sulfhydryl Compounds
2
2020
176
0.120
Why?
Mass Spectrometry
4
2012
622
0.120
Why?
DNA Repair
1
2016
184
0.120
Why?
Enzyme-Linked Immunosorbent Assay
1
2016
787
0.120
Why?
Pituitary Neoplasms
1
2015
156
0.120
Why?
Computer Simulation
4
2014
873
0.110
Why?
Endoplasmic Reticulum Stress
1
2014
92
0.110
Why?
Heat-Shock Proteins
1
2014
112
0.110
Why?
Mammary Glands, Animal
2
2011
117
0.110
Why?
Inflammation
2
2022
2464
0.110
Why?
Fatty Liver, Alcoholic
1
2013
14
0.110
Why?
Protein Folding
2
2014
239
0.110
Why?
Adenosine Triphosphatases
1
2014
152
0.110
Why?
Lactation
2
2011
149
0.110
Why?
Antimetabolites, Antineoplastic
1
2013
80
0.110
Why?
Protein Tyrosine Phosphatases
1
2014
147
0.110
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2021
1356
0.110
Why?
Cell Cycle
2
2014
541
0.110
Why?
Hypoxanthine Phosphoribosyltransferase
1
2013
24
0.110
Why?
Gene Expression Regulation
3
2013
2321
0.100
Why?
Electrophoresis, Polyacrylamide Gel
1
2013
315
0.100
Why?
Gout
1
2013
36
0.100
Why?
Electron Transport Complex I
1
2012
33
0.100
Why?
PTEN Phosphohydrolase
1
2013
140
0.100
Why?
Status Epilepticus
1
2012
32
0.100
Why?
Apoptosis
6
2021
2349
0.100
Why?
Fatty Acid-Binding Proteins
1
2012
60
0.100
Why?
Glutathione Reductase
1
2011
21
0.100
Why?
Acridines
1
2011
7
0.100
Why?
Glutathione Peroxidase
1
2011
40
0.100
Why?
DNA Topoisomerases, Type II
1
2011
44
0.100
Why?
Glutathione Transferase
1
2011
93
0.090
Why?
Intracellular Signaling Peptides and Proteins
1
2014
388
0.090
Why?
Flavoproteins
1
2011
7
0.090
Why?
Receptors, Cytoplasmic and Nuclear
1
2013
192
0.090
Why?
Xenograft Model Antitumor Assays
4
2021
695
0.090
Why?
Myocytes, Cardiac
1
2015
449
0.090
Why?
Transcriptional Activation
1
2013
337
0.090
Why?
Glycolipids
1
2011
35
0.090
Why?
Mitochondria, Liver
1
2011
67
0.090
Why?
Organelles
1
2011
51
0.090
Why?
Indoles
2
2015
300
0.090
Why?
Brain
2
2012
2355
0.090
Why?
Hydrogen Peroxide
1
2012
288
0.090
Why?
Histone-Lysine N-Methyltransferase
1
2011
96
0.090
Why?
Breast Neoplasms
2
2020
1846
0.090
Why?
Sirtuin 3
1
2011
51
0.090
Why?
Superoxide Dismutase
1
2012
305
0.090
Why?
Carcinoma, Hepatocellular
1
2012
210
0.090
Why?
Enzyme Activation
2
2013
771
0.090
Why?
Milk
1
2011
123
0.090
Why?
Protein Processing, Post-Translational
1
2012
399
0.090
Why?
Oxidative Stress
2
2014
1068
0.080
Why?
Cell Movement
1
2014
863
0.080
Why?
Kinetics
1
2013
1547
0.080
Why?
Phospholipids
1
2011
194
0.080
Why?
Adenosine Triphosphate
1
2011
428
0.080
Why?
Thioredoxin-Disulfide Reductase
1
2009
14
0.080
Why?
Peroxiredoxin VI
1
2008
5
0.080
Why?
Tumor Cells, Cultured
3
2022
845
0.080
Why?
Protein Structure, Tertiary
4
2014
796
0.080
Why?
Down-Regulation
1
2011
594
0.080
Why?
DNA-Binding Proteins
2
2013
1311
0.080
Why?
Mutation
4
2021
3338
0.080
Why?
Lipid Metabolism
1
2011
441
0.080
Why?
Protein Interaction Domains and Motifs
3
2013
129
0.070
Why?
Cross-Linking Reagents
1
2008
179
0.070
Why?
Quinones
1
2007
10
0.070
Why?
Spectrophotometry, Infrared
1
2007
43
0.070
Why?
Cell Membrane
1
2011
670
0.070
Why?
Acrolein
1
2007
23
0.070
Why?
NF-kappa B p50 Subunit
1
2007
25
0.070
Why?
Energy Metabolism
1
2012
727
0.070
Why?
Anti-Bacterial Agents
2
2024
1471
0.070
Why?
Galactosides
1
2006
3
0.070
Why?
beta-Galactosidase
1
2006
62
0.070
Why?
RNA, Messenger
2
2024
2550
0.070
Why?
Substrate Specificity
3
2014
350
0.060
Why?
Arginine
3
2013
236
0.060
Why?
Carcinoma
1
2007
198
0.060
Why?
Magnetic Resonance Spectroscopy
1
2007
474
0.060
Why?
Nitroimidazoles
1
2005
6
0.060
Why?
Computational Biology
1
2008
528
0.060
Why?
Spectrometry, Mass, Electrospray Ionization
3
2011
161
0.060
Why?
Biological Availability
1
2005
119
0.060
Why?
Emetine
1
2024
7
0.060
Why?
Aldehyde Dehydrogenase, Mitochondrial
2
2014
22
0.060
Why?
Mice, Nude
2
2021
628
0.060
Why?
Mice, Inbred C57BL
4
2014
4680
0.050
Why?
Polycomb-Group Proteins
1
2023
29
0.050
Why?
Peptides
2
2023
848
0.050
Why?
Cryoelectron Microscopy
1
2024
142
0.050
Why?
Disease Models, Animal
3
2022
3498
0.050
Why?
Insulin Resistance
1
2011
1072
0.050
Why?
Benzamides
1
2023
168
0.050
Why?
Ribosomes
1
2024
148
0.050
Why?
Exoribonucleases
1
2023
40
0.050
Why?
Stress, Physiological
2
2015
379
0.050
Why?
Molecular Conformation
2
2015
135
0.050
Why?
Ethanol
3
2012
534
0.050
Why?
Alcohols
1
2022
28
0.050
Why?
Phospholipase C beta
1
2022
25
0.050
Why?
Mesocricetus
1
2022
29
0.050
Why?
Hep G2 Cells
2
2013
59
0.050
Why?
Ear
1
2022
31
0.050
Why?
Peptide Mapping
2
2012
60
0.050
Why?
High-Throughput Screening Assays
1
2023
123
0.050
Why?
Serine Endopeptidases
1
2022
101
0.050
Why?
Sequence Alignment
2
2012
323
0.050
Why?
Oximes
1
2021
19
0.050
Why?
Perilipin-2
2
2011
36
0.050
Why?
Oxidative Phosphorylation
1
2022
154
0.050
Why?
Angiogenesis Inhibitors
1
2003
213
0.050
Why?
Spike Glycoprotein, Coronavirus
1
2022
92
0.050
Why?
Neural Crest
1
2022
117
0.050
Why?
Indazoles
1
2021
57
0.040
Why?
Cell-Free System
2
2011
47
0.040
Why?
Antibodies, Monoclonal
1
2006
1257
0.040
Why?
Viral Load
1
2022
405
0.040
Why?
HEK293 Cells
2
2013
590
0.040
Why?
Blotting, Western
2
2013
1143
0.040
Why?
Lipoproteins
1
2020
159
0.040
Why?
Carbon
1
2020
155
0.040
Why?
T-Lymphocytes
1
2007
1735
0.040
Why?
MAP Kinase Signaling System
1
2021
271
0.040
Why?
Female
8
2022
59325
0.040
Why?
Microglia
1
2020
198
0.040
Why?
Tandem Mass Spectrometry
2
2013
410
0.040
Why?
Genomics
2
2014
633
0.040
Why?
Piperazines
1
2021
310
0.040
Why?
Triglycerides
1
2020
467
0.040
Why?
Neoplasm Transplantation
1
2019
227
0.040
Why?
Amyloid beta-Peptides
1
2020
189
0.040
Why?
Child
1
2016
18400
0.040
Why?
Drug Resistance, Multiple
1
2017
19
0.040
Why?
Dimerization
1
2017
176
0.030
Why?
Models, Biological
2
2014
1611
0.030
Why?
Rats, Sprague-Dawley
2
2012
2182
0.030
Why?
Adult
1
2016
30375
0.030
Why?
Nitroglycerin
1
2014
19
0.030
Why?
Male
6
2022
55396
0.030
Why?
Circular Dichroism
1
2015
135
0.030
Why?
Phenotype
1
2022
2784
0.030
Why?
Spectrophotometry, Ultraviolet
1
2014
73
0.030
Why?
Unfolded Protein Response
1
2014
44
0.030
Why?
Calorimetry
1
2014
60
0.030
Why?
Lung
2
2022
3521
0.030
Why?
Macrophages
1
2020
1259
0.030
Why?
Magnesium
1
2014
144
0.030
Why?
Sequence Homology, Amino Acid
1
2014
353
0.030
Why?
Cell Cycle Checkpoints
1
2013
84
0.030
Why?
Retinoid X Receptors
1
2013
39
0.030
Why?
Caco-2 Cells
1
2013
66
0.030
Why?
RNA Splice Sites
1
2013
33
0.030
Why?
Tumor Microenvironment
1
2015
428
0.030
Why?
Telomere
1
2015
202
0.030
Why?
Hyperuricemia
1
2013
43
0.030
Why?
Synaptosomes
1
2012
12
0.030
Why?
Biotinylation
1
2012
26
0.030
Why?
Kainic Acid
1
2012
31
0.030
Why?
Rats
2
2012
4913
0.030
Why?
Fishes
1
2013
80
0.030
Why?
Anilino Naphthalenesulfonates
1
2012
10
0.030
Why?
Excitatory Amino Acid Agonists
1
2012
37
0.030
Why?
Methyltransferases
1
2013
61
0.030
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2014
238
0.030
Why?
Sulfonamides
1
2015
444
0.030
Why?
Electron Transport Complex IV
1
2012
53
0.030
Why?
Anura
1
2012
41
0.030
Why?
Electrophoresis, Gel, Two-Dimensional
1
2012
99
0.020
Why?
ATP-Binding Cassette Transporters
1
2013
122
0.020
Why?
Cysteine Proteinase Inhibitors
1
2012
45
0.020
Why?
Endoplasmic Reticulum
1
2014
234
0.020
Why?
Molecular Weight
1
2012
328
0.020
Why?
Ubiquitination
1
2012
86
0.020
Why?
Gene Knockout Techniques
1
2012
98
0.020
Why?
Genome, Human
1
2014
347
0.020
Why?
Immunoprecipitation
1
2012
151
0.020
Why?
Inhibitory Concentration 50
1
2011
74
0.020
Why?
Amination
1
2011
2
0.020
Why?
Chromatography, Liquid
1
2013
345
0.020
Why?
Nucleic Acid Conformation
1
2015
670
0.020
Why?
Alkylation
1
2011
18
0.020
Why?
Oxidants
1
2012
112
0.020
Why?
Immunohistochemistry
1
2015
1624
0.020
Why?
Embryo, Mammalian
1
2012
213
0.020
Why?
Protein Subunits
1
2012
200
0.020
Why?
Histone Deacetylase Inhibitors
1
2013
197
0.020
Why?
Lipid Droplets
1
2011
21
0.020
Why?
Binding, Competitive
1
2011
192
0.020
Why?
Metabolic Networks and Pathways
1
2012
167
0.020
Why?
Glycogen Synthase Kinase 3 beta
1
2011
60
0.020
Why?
Cloning, Molecular
1
2012
522
0.020
Why?
DNA Primers
1
2012
508
0.020
Why?
Ligands
1
2013
557
0.020
Why?
Mammary Glands, Human
1
2011
60
0.020
Why?
NAD
1
2011
63
0.020
Why?
Glycogen Synthase Kinase 3
1
2011
77
0.020
Why?
Lipid Peroxidation
1
2011
139
0.020
Why?
Membranes, Artificial
1
2011
64
0.020
Why?
Mammals
1
2012
241
0.020
Why?
Acetylation
1
2011
209
0.020
Why?
Phosphatidylinositol 3-Kinases
1
2012
328
0.020
Why?
Transfection
1
2012
863
0.020
Why?
Protein Structure, Secondary
1
2011
325
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2012
924
0.020
Why?
In Vitro Techniques
1
2011
1003
0.020
Why?
Hypoxia
1
2015
956
0.020
Why?
Analysis of Variance
1
2012
1218
0.020
Why?
DNA Breaks, Single-Stranded
1
2009
5
0.020
Why?
Phylogeny
1
2012
787
0.020
Why?
Evolution, Molecular
1
2012
430
0.020
Why?
Gene Expression Regulation, Neoplastic
1
2014
1142
0.020
Why?
Animal Feed
1
2008
49
0.020
Why?
NADPH-Ferrihemoprotein Reductase
1
2008
10
0.020
Why?
Promoter Regions, Genetic
1
2013
1131
0.020
Why?
Microsomes, Liver
1
2008
54
0.020
Why?
Liver Neoplasms
1
2012
504
0.020
Why?
Caspases
1
2009
243
0.020
Why?
Oxygen
1
2012
851
0.020
Why?
Mitochondria
1
2012
744
0.020
Why?
Transcription Factor AP-1
1
2007
81
0.020
Why?
Tetrazolium Salts
1
2006
18
0.020
Why?
NFATC Transcription Factors
1
2007
78
0.020
Why?
Proteomics
1
2012
815
0.020
Why?
Indicators and Reagents
1
2006
99
0.020
Why?
Cell Respiration
1
2006
71
0.020
Why?
Thiazoles
1
2006
110
0.020
Why?
Deoxyuridine
1
2006
6
0.020
Why?
Cysteine
1
2007
171
0.020
Why?
Smoke
1
2007
123
0.020
Why?
Drug Carriers
1
2006
112
0.020
Why?
Superoxides
1
2006
190
0.020
Why?
Drug Interactions
1
2006
337
0.020
Why?
Colonic Neoplasms
1
2006
212
0.010
Why?
Drug Delivery Systems
1
2006
295
0.010
Why?
Oxygen Consumption
1
2006
587
0.010
Why?
Respiratory Tract Infections
1
2007
319
0.010
Why?
Time Factors
1
2012
6077
0.010
Why?
Liver
1
2008
1633
0.010
Why?
Aged
1
2019
18969
0.010
Why?
Child, Preschool
1
2014
9114
0.010
Why?
Cytokines
1
2007
1824
0.010
Why?
Middle Aged
1
2019
26605
0.010
Why?
Reigan's Networks
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