Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Philip Reigan

Concepts (395)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Ribosomal Protein S6 Kinases, 90-kDa
5
2025
14
2.900
Why?
Protein Kinase Inhibitors
10
2025
916
2.510
Why?
Thymidine Phosphorylase
7
2022
14
2.340
Why?
Antineoplastic Agents
17
2025
2129
2.330
Why?
Pyrimidines
6
2021
470
1.670
Why?
Protein-Tyrosine Kinases
6
2019
434
1.540
Why?
AMP-Activated Protein Kinases
2
2025
197
1.410
Why?
Cell Cycle Proteins
5
2018
611
1.360
Why?
Nuclear Proteins
6
2018
710
1.350
Why?
Enzyme Inhibitors
9
2021
838
1.210
Why?
Neoplasms
6
2025
2644
1.200
Why?
Models, Molecular
26
2025
1591
1.090
Why?
STAT3 Transcription Factor
3
2022
205
1.060
Why?
Glioblastoma
3
2022
343
1.030
Why?
Pyrazoles
4
2018
423
0.940
Why?
Pyrroles
2
2021
211
0.870
Why?
Small Molecule Libraries
3
2025
95
0.830
Why?
Prodrugs
4
2007
49
0.780
Why?
Drug Resistance, Neoplasm
5
2025
800
0.750
Why?
NAD(P)H Dehydrogenase (Quinone)
8
2011
32
0.730
Why?
Pyrimidinones
4
2018
113
0.720
Why?
Protein Isoforms
2
2025
400
0.690
Why?
Purines
1
2021
176
0.660
Why?
Pteridines
1
2020
20
0.650
Why?
Cell Survival
8
2022
1117
0.630
Why?
Structure-Activity Relationship
10
2020
573
0.620
Why?
Indolequinones
5
2011
5
0.600
Why?
Aldehydes
8
2014
144
0.560
Why?
HSP90 Heat-Shock Proteins
5
2011
46
0.560
Why?
Protein Binding
12
2021
2223
0.520
Why?
Medulloblastoma
2
2016
196
0.510
Why?
Glutamate-Cysteine Ligase
2
2013
20
0.510
Why?
Brain Neoplasms
3
2020
1241
0.500
Why?
Xanthine Oxidase
2
2007
81
0.490
Why?
Benzoquinones
4
2011
48
0.480
Why?
Cell Line, Tumor
18
2022
3399
0.480
Why?
Uracil
3
2021
31
0.470
Why?
Isoxazoles
5
2023
54
0.450
Why?
Molecular Dynamics Simulation
4
2025
238
0.430
Why?
Hydroquinones
3
2011
29
0.430
Why?
Cisplatin
1
2016
318
0.430
Why?
Lactams, Macrocyclic
3
2011
49
0.420
Why?
Deoxyribose
1
2013
6
0.420
Why?
Drug Screening Assays, Antitumor
5
2020
193
0.400
Why?
Glutathione
2
2011
357
0.390
Why?
Humans
59
2025
136783
0.380
Why?
Molecular Structure
5
2020
495
0.350
Why?
Molecular Docking Simulation
6
2023
112
0.340
Why?
Catalytic Domain
5
2021
226
0.310
Why?
Protein Conformation
4
2021
940
0.310
Why?
Cell Line
5
2022
2836
0.310
Why?
Glucose
2
2013
1019
0.300
Why?
Cell Proliferation
10
2020
2473
0.300
Why?
Aldehyde Dehydrogenase
3
2014
100
0.300
Why?
Imidazoles
3
2021
239
0.300
Why?
Molecular Targeted Therapy
3
2016
413
0.290
Why?
Proto-Oncogene Proteins B-raf
2
2021
226
0.280
Why?
Amides
2
2020
93
0.280
Why?
Growth Inhibitors
1
2007
43
0.270
Why?
Animals
29
2025
36768
0.270
Why?
Signal Transduction
6
2022
5065
0.270
Why?
Proto-Oncogene Proteins c-akt
4
2013
436
0.260
Why?
src Homology Domains
2
2016
41
0.250
Why?
Thyroid Neoplasms
2
2021
337
0.240
Why?
Pancreatic Neoplasms
4
2009
931
0.240
Why?
Binding Sites
6
2018
1308
0.230
Why?
Tumor Suppressor Protein p53
2
2023
530
0.230
Why?
Rotenone
1
2024
11
0.230
Why?
G-Quadruplexes
2
2022
19
0.220
Why?
Pyrrolidines
1
2004
80
0.220
Why?
alpha-Synuclein
1
2024
34
0.220
Why?
Giardia lamblia
1
2024
22
0.210
Why?
Dopaminergic Neurons
1
2024
64
0.210
Why?
Thymidine
2
2022
60
0.210
Why?
Neuroprotective Agents
1
2024
132
0.200
Why?
Rifabutin
3
2008
6
0.200
Why?
Polycomb Repressive Complex 1
1
2023
50
0.200
Why?
Receptors, Glucocorticoid
1
2024
155
0.200
Why?
DNA
3
2016
1458
0.200
Why?
Liver Diseases, Alcoholic
2
2014
93
0.190
Why?
Tumor Microenvironment
2
2025
671
0.190
Why?
Ear Diseases
1
2022
15
0.190
Why?
Amino Acid Transport System ASC
1
2022
12
0.190
Why?
K562 Cells
2
2020
89
0.190
Why?
Virus Internalization
1
2022
47
0.190
Why?
Models, Chemical
1
2023
268
0.190
Why?
Minor Histocompatibility Antigens
1
2022
48
0.190
Why?
Catalysis
3
2013
316
0.180
Why?
Drug Synergism
3
2021
378
0.180
Why?
Quinone Reductases
2
2011
17
0.180
Why?
Fluorouracil
1
2022
210
0.180
Why?
Maneb
1
2020
9
0.170
Why?
Proto-Oncogene Proteins c-myc
1
2022
139
0.170
Why?
Receptors, Androgen
1
2022
149
0.170
Why?
Heterocyclic Compounds
1
2020
20
0.170
Why?
Mice
18
2024
17731
0.170
Why?
Lipoprotein Lipase
1
2020
59
0.170
Why?
Mitogen-Activated Protein Kinase 3
1
2021
152
0.170
Why?
Dose-Response Relationship, Drug
3
2020
2045
0.170
Why?
Fluorescence
1
2020
159
0.170
Why?
Mitogen-Activated Protein Kinase 1
1
2021
185
0.170
Why?
Neovascularization, Pathologic
1
2022
301
0.170
Why?
Polymorphism, Genetic
2
2014
657
0.160
Why?
Amino Acid Sequence
8
2014
2145
0.150
Why?
Adenocarcinoma, Follicular
1
2019
36
0.150
Why?
Mice, Inbred C57BL
5
2024
5744
0.150
Why?
Thyroid Carcinoma, Anaplastic
1
2019
34
0.150
Why?
Protein Carbonylation
3
2013
54
0.150
Why?
Enzyme Assays
1
2018
25
0.150
Why?
CDC2 Protein Kinase
1
2018
31
0.150
Why?
Chromatography, High Pressure Liquid
5
2013
591
0.150
Why?
Pyridazines
1
2018
56
0.140
Why?
Receptors, Metabotropic Glutamate
1
2018
40
0.140
Why?
Phosphorylation
3
2018
1756
0.140
Why?
Escherichia coli
4
2006
812
0.140
Why?
Neoplastic Stem Cells
1
2022
397
0.140
Why?
Proto-Oncogene Proteins p21(ras)
1
2019
267
0.140
Why?
Dihydropyridines
1
2017
15
0.140
Why?
Glucocorticoids
1
2022
596
0.140
Why?
Cyclic S-Oxides
1
2016
1
0.130
Why?
Niclosamide
1
2016
2
0.130
Why?
Glycoproteins
2
2011
344
0.130
Why?
Leukemia, Myeloid, Acute
2
2022
619
0.130
Why?
Fluorescence Polarization
1
2016
37
0.130
Why?
Oncogene Proteins, Fusion
1
2019
214
0.130
Why?
Antigens, Neoplasm
2
2011
320
0.130
Why?
Lysine
2
2023
293
0.130
Why?
G2 Phase Cell Cycle Checkpoints
1
2016
44
0.130
Why?
M Phase Cell Cycle Checkpoints
1
2016
24
0.130
Why?
Antioxidants
2
2011
578
0.130
Why?
MicroRNAs
1
2023
697
0.130
Why?
Molecular Sequence Data
7
2014
2903
0.130
Why?
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
2
2013
144
0.120
Why?
Quantitative Structure-Activity Relationship
1
2015
19
0.120
Why?
Antiviral Agents
1
2022
736
0.120
Why?
Immunity, Innate
1
2022
826
0.120
Why?
Crystallography, X-Ray
5
2017
485
0.120
Why?
Small-Conductance Calcium-Activated Potassium Channels
1
2015
12
0.120
Why?
Drug Design
1
2016
166
0.120
Why?
Cells, Cultured
3
2020
4194
0.120
Why?
Oxidation-Reduction
5
2020
1062
0.120
Why?
Retinaldehyde
1
2014
4
0.120
Why?
Allosteric Regulation
3
2023
97
0.120
Why?
Acetaldehyde
1
2014
17
0.120
Why?
HeLa Cells
1
2016
636
0.120
Why?
Parkinson Disease
1
2020
491
0.110
Why?
Drug Discovery
1
2016
141
0.110
Why?
Sulfhydryl Compounds
2
2020
191
0.110
Why?
Recombinant Proteins
5
2011
1354
0.110
Why?
Mass Spectrometry
4
2012
739
0.110
Why?
Alzheimer Disease
1
2020
557
0.110
Why?
Membrane Proteins
2
2011
1162
0.110
Why?
DNA Repair
1
2016
230
0.110
Why?
Enzyme-Linked Immunosorbent Assay
1
2016
849
0.110
Why?
Computer Simulation
4
2014
973
0.110
Why?
Pituitary Neoplasms
1
2015
190
0.110
Why?
Endoplasmic Reticulum Stress
1
2014
108
0.110
Why?
Fatty Liver, Alcoholic
1
2013
15
0.100
Why?
Heat-Shock Proteins
1
2014
142
0.100
Why?
Protein Folding
2
2014
281
0.100
Why?
Mammary Glands, Animal
2
2011
129
0.100
Why?
Adenosine Triphosphatases
1
2014
165
0.100
Why?
Antimetabolites, Antineoplastic
1
2013
94
0.100
Why?
Hypoxanthine Phosphoribosyltransferase
1
2013
25
0.100
Why?
Lactation
2
2011
181
0.100
Why?
Protein Tyrosine Phosphatases
1
2014
171
0.100
Why?
Electrophoresis, Polyacrylamide Gel
1
2013
345
0.100
Why?
Cell Cycle
2
2014
601
0.100
Why?
Inflammation
2
2022
2834
0.100
Why?
Gout
1
2013
36
0.100
Why?
Gene Expression Regulation
3
2013
2603
0.100
Why?
Electron Transport Complex I
1
2012
41
0.100
Why?
PTEN Phosphohydrolase
1
2013
162
0.090
Why?
Acridines
1
2011
7
0.090
Why?
Fatty Acid-Binding Proteins
1
2012
70
0.090
Why?
Glutathione Reductase
1
2011
25
0.090
Why?
Status Epilepticus
1
2012
50
0.090
Why?
Glutathione Peroxidase
1
2011
43
0.090
Why?
Apoptosis
6
2021
2548
0.090
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2021
1683
0.090
Why?
DNA Topoisomerases, Type II
1
2011
45
0.090
Why?
Glutathione Transferase
1
2011
104
0.090
Why?
Flavoproteins
1
2011
8
0.090
Why?
Receptors, Cytoplasmic and Nuclear
1
2013
219
0.090
Why?
Intracellular Signaling Peptides and Proteins
1
2014
455
0.090
Why?
Glycolipids
1
2011
42
0.090
Why?
Mitochondria, Liver
1
2011
73
0.090
Why?
Transcriptional Activation
1
2013
378
0.090
Why?
Organelles
1
2011
58
0.090
Why?
Myocytes, Cardiac
1
2015
528
0.090
Why?
Hydrogen Peroxide
1
2012
320
0.080
Why?
Xenograft Model Antitumor Assays
4
2021
864
0.080
Why?
Sirtuin 3
1
2011
61
0.080
Why?
Milk
1
2011
124
0.080
Why?
Enzyme Activation
2
2013
813
0.080
Why?
Brain
2
2012
2669
0.080
Why?
Superoxide Dismutase
1
2012
346
0.080
Why?
Histone-Lysine N-Methyltransferase
1
2011
137
0.080
Why?
Protein Processing, Post-Translational
1
2012
467
0.080
Why?
Kinetics
1
2013
1668
0.080
Why?
Indoles
2
2015
410
0.080
Why?
Cell Movement
1
2014
969
0.080
Why?
Phospholipids
1
2011
222
0.080
Why?
Thioredoxin-Disulfide Reductase
1
2009
13
0.080
Why?
Breast Neoplasms
2
2020
2239
0.080
Why?
Oxidative Stress
2
2014
1309
0.080
Why?
Adenosine Triphosphate
1
2011
486
0.080
Why?
Peroxiredoxin VI
1
2008
5
0.080
Why?
Tumor Cells, Cultured
3
2022
953
0.080
Why?
Protein Structure, Tertiary
4
2014
867
0.080
Why?
Carcinoma, Hepatocellular
1
2012
360
0.070
Why?
Down-Regulation
1
2011
657
0.070
Why?
Disease Models, Animal
4
2024
4279
0.070
Why?
Protein Interaction Domains and Motifs
3
2013
151
0.070
Why?
Cross-Linking Reagents
1
2008
212
0.070
Why?
Quinones
1
2007
9
0.070
Why?
Lipid Metabolism
1
2011
512
0.070
Why?
DNA-Binding Proteins
2
2013
1500
0.070
Why?
Spectrophotometry, Infrared
1
2007
54
0.070
Why?
Acrolein
1
2007
23
0.070
Why?
NF-kappa B p50 Subunit
1
2007
26
0.070
Why?
Mutation
4
2021
3953
0.070
Why?
Cell Membrane
1
2011
736
0.070
Why?
Galactosides
1
2006
5
0.070
Why?
beta-Galactosidase
1
2006
77
0.060
Why?
Energy Metabolism
1
2012
918
0.060
Why?
Substrate Specificity
3
2014
384
0.060
Why?
Anti-Bacterial Agents
2
2024
1799
0.060
Why?
Arginine
3
2013
271
0.060
Why?
RNA, Messenger
2
2024
2831
0.060
Why?
Nitroimidazoles
1
2005
9
0.060
Why?
Carcinoma
1
2007
236
0.060
Why?
Spectrometry, Mass, Electrospray Ionization
3
2011
180
0.060
Why?
Biological Availability
1
2005
147
0.060
Why?
Magnetic Resonance Spectroscopy
1
2007
616
0.060
Why?
Phenanthrenes
1
2024
13
0.060
Why?
Emetine
1
2024
6
0.050
Why?
Parkinsonian Disorders
1
2024
35
0.050
Why?
Aldehyde Dehydrogenase, Mitochondrial
2
2014
23
0.050
Why?
Substantia Nigra
1
2024
57
0.050
Why?
Computational Biology
1
2008
645
0.050
Why?
Mice, Nude
2
2021
692
0.050
Why?
Polycomb-Group Proteins
1
2023
28
0.050
Why?
Cryoelectron Microscopy
1
2024
188
0.050
Why?
Benzamides
1
2023
217
0.050
Why?
Insulin Resistance
1
2011
1201
0.050
Why?
Exoribonucleases
1
2023
49
0.050
Why?
Ribosomes
1
2024
185
0.050
Why?
Peptides
2
2023
980
0.050
Why?
Alcohols
1
2022
29
0.050
Why?
Molecular Conformation
2
2015
150
0.050
Why?
Phospholipase C beta
1
2022
29
0.050
Why?
Mesocricetus
1
2022
39
0.050
Why?
Hep G2 Cells
2
2013
65
0.050
Why?
Ear
1
2022
31
0.050
Why?
Stress, Physiological
2
2015
442
0.050
Why?
Ethanol
3
2012
608
0.050
Why?
Peptide Mapping
2
2012
64
0.050
Why?
High-Throughput Screening Assays
1
2023
160
0.050
Why?
Sequence Alignment
2
2012
345
0.040
Why?
Serine Endopeptidases
1
2022
123
0.040
Why?
Oximes
1
2021
24
0.040
Why?
Perilipin-2
2
2011
41
0.040
Why?
Angiogenesis Inhibitors
1
2003
226
0.040
Why?
Neural Crest
1
2022
116
0.040
Why?
Spike Glycoprotein, Coronavirus
1
2022
107
0.040
Why?
Oxidative Phosphorylation
1
2022
193
0.040
Why?
Indazoles
1
2021
69
0.040
Why?
Cell-Free System
2
2011
53
0.040
Why?
Blotting, Western
2
2013
1225
0.040
Why?
Viral Load
1
2022
460
0.040
Why?
HEK293 Cells
2
2013
728
0.040
Why?
Lipoproteins
1
2020
167
0.040
Why?
Antibodies, Monoclonal
1
2006
1428
0.040
Why?
Carbon
1
2020
223
0.040
Why?
MAP Kinase Signaling System
1
2021
321
0.040
Why?
T-Lymphocytes
1
2007
1998
0.040
Why?
Piperazines
1
2021
350
0.040
Why?
Neoplasm Transplantation
1
2019
256
0.040
Why?
Triglycerides
1
2020
524
0.040
Why?
Microglia
1
2020
251
0.040
Why?
Amyloid beta-Peptides
1
2020
221
0.040
Why?
Tandem Mass Spectrometry
2
2013
532
0.040
Why?
Genomics
2
2014
790
0.040
Why?
Male
7
2024
67361
0.030
Why?
Drug Resistance, Multiple
1
2017
25
0.030
Why?
Female
8
2022
72840
0.030
Why?
Dimerization
1
2017
198
0.030
Why?
Child
1
2016
21968
0.030
Why?
Models, Biological
2
2014
1769
0.030
Why?
Nitroglycerin
1
2014
17
0.030
Why?
Rats, Sprague-Dawley
2
2012
2481
0.030
Why?
Circular Dichroism
1
2015
150
0.030
Why?
Spectrophotometry, Ultraviolet
1
2014
86
0.030
Why?
Unfolded Protein Response
1
2014
58
0.030
Why?
Calorimetry
1
2014
69
0.030
Why?
Magnesium
1
2014
158
0.030
Why?
Sequence Homology, Amino Acid
1
2014
387
0.030
Why?
Phenotype
1
2022
3199
0.030
Why?
Adult
1
2016
37616
0.030
Why?
Cell Cycle Checkpoints
1
2013
98
0.030
Why?
Retinoid X Receptors
1
2013
39
0.030
Why?
Lung
2
2022
4065
0.030
Why?
Caco-2 Cells
1
2013
76
0.030
Why?
RNA Splice Sites
1
2013
45
0.030
Why?
Hyperuricemia
1
2013
44
0.030
Why?
Macrophages
1
2020
1541
0.020
Why?
Biotinylation
1
2012
32
0.020
Why?
Kainic Acid
1
2012
35
0.020
Why?
Synaptosomes
1
2012
30
0.020
Why?
Excitatory Amino Acid Agonists
1
2012
39
0.020
Why?
Anilino Naphthalenesulfonates
1
2012
10
0.020
Why?
Anura
1
2012
39
0.020
Why?
Electron Transport Complex IV
1
2012
59
0.020
Why?
Fishes
1
2013
100
0.020
Why?
Methyltransferases
1
2013
78
0.020
Why?
Cysteine Proteinase Inhibitors
1
2012
49
0.020
Why?
Electrophoresis, Gel, Two-Dimensional
1
2012
114
0.020
Why?
ATP-Binding Cassette Transporters
1
2013
137
0.020
Why?
Molecular Weight
1
2012
334
0.020
Why?
Ubiquitination
1
2012
102
0.020
Why?
Immunoprecipitation
1
2012
155
0.020
Why?
Sulfonamides
1
2015
512
0.020
Why?
Gene Knockout Techniques
1
2012
115
0.020
Why?
Rats
2
2012
5628
0.020
Why?
Telomere
1
2015
280
0.020
Why?
Endoplasmic Reticulum
1
2014
264
0.020
Why?
Inhibitory Concentration 50
1
2011
90
0.020
Why?
Amination
1
2011
2
0.020
Why?
Oxidants
1
2012
110
0.020
Why?
Nuclear Magnetic Resonance, Biomolecular
1
2014
340
0.020
Why?
Alkylation
1
2011
26
0.020
Why?
Nucleic Acid Conformation
1
2015
729
0.020
Why?
Genome, Human
1
2014
424
0.020
Why?
Embryo, Mammalian
1
2012
231
0.020
Why?
Protein Subunits
1
2012
239
0.020
Why?
Immunohistochemistry
1
2015
1731
0.020
Why?
Lipid Droplets
1
2011
23
0.020
Why?
Chromatography, Liquid
1
2013
432
0.020
Why?
Binding, Competitive
1
2011
202
0.020
Why?
Histone Deacetylase Inhibitors
1
2013
210
0.020
Why?
DNA Primers
1
2012
513
0.020
Why?
Cloning, Molecular
1
2012
534
0.020
Why?
Metabolic Networks and Pathways
1
2012
182
0.020
Why?
Glycogen Synthase Kinase 3 beta
1
2011
72
0.020
Why?
Glycogen Synthase Kinase 3
1
2011
82
0.020
Why?
Membranes, Artificial
1
2011
72
0.020
Why?
Mammary Glands, Human
1
2011
64
0.020
Why?
Lipid Peroxidation
1
2011
152
0.020
Why?
Ligands
1
2013
664
0.020
Why?
NAD
1
2011
77
0.020
Why?
Mammals
1
2012
283
0.020
Why?
Acetylation
1
2011
248
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2012
973
0.020
Why?
Phosphatidylinositol 3-Kinases
1
2012
365
0.020
Why?
Protein Structure, Secondary
1
2011
376
0.020
Why?
Transfection
1
2012
945
0.020
Why?
In Vitro Techniques
1
2011
1089
0.020
Why?
DNA Breaks, Single-Stranded
1
2009
5
0.020
Why?
Analysis of Variance
1
2012
1318
0.020
Why?
Phylogeny
1
2012
896
0.020
Why?
Animal Feed
1
2008
53
0.020
Why?
NADPH-Ferrihemoprotein Reductase
1
2008
11
0.020
Why?
Evolution, Molecular
1
2012
488
0.020
Why?
Hypoxia
1
2015
1107
0.020
Why?
Microsomes, Liver
1
2008
86
0.020
Why?
Promoter Regions, Genetic
1
2013
1250
0.020
Why?
Caspases
1
2009
247
0.020
Why?
Gene Expression Regulation, Neoplastic
1
2014
1396
0.020
Why?
Oxygen
1
2012
933
0.020
Why?
Tetrazolium Salts
1
2006
17
0.020
Why?
Transcription Factor AP-1
1
2007
92
0.020
Why?
NFATC Transcription Factors
1
2007
95
0.020
Why?
Indicators and Reagents
1
2006
106
0.020
Why?
Deoxyuridine
1
2006
6
0.020
Why?
Cell Respiration
1
2006
102
0.020
Why?
Thiazoles
1
2006
123
0.020
Why?
Smoke
1
2007
144
0.020
Why?
Cysteine
1
2007
205
0.020
Why?
Mitochondria
1
2012
946
0.020
Why?
Liver Neoplasms
1
2012
784
0.020
Why?
Superoxides
1
2006
202
0.020
Why?
Drug Carriers
1
2006
127
0.020
Why?
Proteomics
1
2012
1108
0.010
Why?
Drug Interactions
1
2006
405
0.010
Why?
Colonic Neoplasms
1
2006
256
0.010
Why?
Drug Delivery Systems
1
2006
362
0.010
Why?
Oxygen Consumption
1
2006
696
0.010
Why?
Respiratory Tract Infections
1
2007
396
0.010
Why?
Time Factors
1
2012
6792
0.010
Why?
Liver
1
2008
1938
0.010
Why?
Aged
1
2019
23729
0.010
Why?
Child, Preschool
1
2014
11069
0.010
Why?
Cytokines
1
2007
2088
0.010
Why?
Middle Aged
1
2019
33200
0.010
Why?
Reigan's Networks
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