 Drug Carriers
"Drug Carriers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.
| Descriptor ID |
D004337
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| MeSH Number(s) |
D26.255.260 E02.319.300.380
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Drug Carriers".
Below are MeSH descriptors whose meaning is more specific than "Drug Carriers".
This graph shows the total number of publications written about "Drug Carriers" by people in this website by year, and whether "Drug Carriers" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 | | 1998 | 1 | 2 | 3 | | 1999 | 0 | 4 | 4 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 1 | 2 | | 2004 | 3 | 2 | 5 | | 2005 | 1 | 2 | 3 | | 2006 | 0 | 5 | 5 | | 2007 | 1 | 1 | 2 | | 2008 | 3 | 4 | 7 | | 2009 | 3 | 2 | 5 | | 2010 | 0 | 2 | 2 | | 2011 | 3 | 0 | 3 | | 2012 | 2 | 1 | 3 | | 2013 | 5 | 3 | 8 | | 2014 | 5 | 2 | 7 | | 2015 | 6 | 2 | 8 | | 2016 | 1 | 1 | 2 | | 2017 | 4 | 3 | 7 | | 2018 | 2 | 2 | 4 | | 2019 | 4 | 1 | 5 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 2 | 3 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Drug Carriers" by people in Profiles.
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Haroon HB, Dhillon E, Farhangrazi ZS, Trohopoulos PN, Simberg D, Moghimi SM. Activation of the complement system by nanoparticles and strategies for complement inhibition. Eur J Pharm Biopharm. 2023 Dec; 193:227-240.
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Tang W, Panja S, Jogdeo CM, Tang S, Ding L, Yu A, Foster KW, Dsouza DL, Chhonker YS, Jensen-Smith H, Jang HS, Boesen EI, Murry DJ, Padanilam B, Oupick? D. Modified chitosan for effective renal delivery of siRNA to treat acute kidney injury. Biomaterials. 2022 06; 285:121562.
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Talkington AM, Wessler T, Lai SK, Cao Y, Forest MG. Experimental Data and PBPK Modeling Quantify Antibody Interference in PEGylated Drug Carrier Delivery. Bull Math Biol. 2021 11 09; 83(12):123.
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Wu LP, Ficker M, Christensen JB, Simberg D, Trohopoulos PN, Moghimi SM. Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking. Nat Commun. 2021 08 11; 12(1):4858.
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Gautam D, Pedler MG, Nair DP, Petrash JM. Nanogel-Facilitated In-Situ Delivery of a Cataract Inhibitor. Biomolecules. 2021 08 04; 11(8).
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Sun F, Wang G, Pradhan A, Xu K, Gomez-Arroyo J, Zhang Y, Kalin GT, Deng Z, Vagnozzi RJ, He H, Dunn AW, Wang Y, York AJ, Hegde RS, Woods JC, Kalin TV, Molkentin JD, Kalinichenko VV. Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia. Circulation. 2021 08 17; 144(7):539-555.
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Das D, Koirala N, Li X, Khan N, Dong F, Zhang W, Mulay P, Shrikhande G, Puskas J, Drazba J, McLennan G. Screening of Polymer-Based Drug Delivery Vehicles Targeting Folate Receptors in Triple-Negative Breast Cancer. J Vasc Interv Radiol. 2020 11; 31(11):1866-1873.e2.
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Perni S, Prokopovich P. Optimisation and feature selection of poly-beta-amino-ester as a drug delivery system for cartilage. J Mater Chem B. 2020 06 17; 8(23):5096-5108.
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Moghimi SM, Simberg D, Papini E, Farhangrazi ZS. Complement activation by drug carriers and particulate pharmaceuticals: Principles, challenges and opportunities. Adv Drug Deliv Rev. 2020; 157:83-95.
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Goel E, Erwin M, Cawthon CV, Schaff C, Fedor N, Rayl T, Wilson O, Christians U, Register TC, Geary RL, Saul J, Yazdani SK. Pre-Clinical Investigation of Keratose as an Excipient of Drug Coated Balloons. Molecules. 2020 Mar 31; 25(7).
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