 Gene Knockout Techniques
"Gene Knockout Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Techniques to alter a gene sequence that result in an inactivated gene, or one in which the expression can be inactivated at a chosen time during development to study the loss of function of a gene.
| Descriptor ID |
D055786
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| MeSH Number(s) |
E05.393.335.750
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| Concept/Terms |
Gene Knockout Techniques- Gene Knockout Techniques
- Gene Knockout Technique
- Knockout Technique, Gene
- Knockout Techniques, Gene
- Technique, Gene Knockout
- Techniques, Gene Knockout
- Gene Knockout
- Gene Knockouts
- Knockout, Gene
- Knockouts, Gene
- Gene Knock-Out Techniques
- Gene Knock-Out Technique
- Knock-Out Technique, Gene
- Knock-Out Techniques, Gene
- Technique, Gene Knock-Out
- Techniques, Gene Knock-Out
- Gene Knock Out
- Gene Knock Outs
- Knock Out, Gene
- Knock Outs, Gene
- Out, Gene Knock
- Outs, Gene Knock
- Gene Knock Out Techniques
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Below are MeSH descriptors whose meaning is more general than "Gene Knockout Techniques".
Below are MeSH descriptors whose meaning is more specific than "Gene Knockout Techniques".
This graph shows the total number of publications written about "Gene Knockout Techniques" by people in this website by year, and whether "Gene Knockout Techniques" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 | | 2009 | 0 | 2 | 2 | | 2010 | 0 | 5 | 5 | | 2011 | 0 | 6 | 6 | | 2012 | 0 | 6 | 6 | | 2013 | 0 | 8 | 8 | | 2014 | 1 | 6 | 7 | | 2015 | 1 | 8 | 9 | | 2016 | 0 | 6 | 6 | | 2017 | 0 | 5 | 5 | | 2018 | 2 | 6 | 8 | | 2019 | 1 | 3 | 4 | | 2020 | 2 | 8 | 10 | | 2021 | 0 | 4 | 4 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 2 | 2 | | 2024 | 0 | 2 | 2 | | 2025 | 2 | 2 | 4 |
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Below are the most recent publications written about "Gene Knockout Techniques" by people in Profiles.
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Liu H, Yu L, Majerciak V, Meyer TJ, Yi M, Johnson PF, Cam M, Lowy DR, Zheng ZM. The long noncoding RNA lnc-FANCI-2 intrinsically restricts RAS signaling in human papillomavirus type 16-infected cervical cancer cells. Elife. 2025 Aug 29; 13.
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Feist WN, Luna SE, Ben-Efraim K, Filsinger Interrante MV, Amorin A, Johnston NM, Bruun TUJ, Utz A, Ghanim HY, Lesch BJ, McLaughlin TM, Dudek AM, Porteus MH. Multilayered HIV-1 resistance in HSPCs through CCR5 Knockout and B cell secretion of HIV-inhibiting antibodies. Nat Commun. 2025 Apr 01; 16(1):3103.
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Cortázar MA, Jagannathan S. SelectRepair Knockout: Efficient PTC-Free Gene Knockout Through Selectable Homology-Directed DNA Repair. Methods Mol Biol. 2025; 2863:397-417.
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Kumar TR. Cre Deleter Mouse Lines for Conditional Knockout of Genes in Testis Cell Types. Methods Mol Biol. 2025; 2954:287-294.
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Donaka R, Zheng H, Ackert-Bicknell CL, Karasik D. Early life lipid overload in Native American Myopathy is phenocopied by stac3 knockout in zebrafish. Gene. 2025 Feb 05; 936:149123.
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Saunders SH, Ahmed AM. ORBIT for E. coli: kilobase-scale oligonucleotide recombineering at high throughput and high efficiency. Nucleic Acids Res. 2024 May 08; 52(8):e43.
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Mangalhara KC, Varanasi SK, Johnson MA, Burns MJ, Rojas GR, Esparza Moltó PB, Sainz AG, Tadepalle N, Abbott KL, Mendiratta G, Chen D, Farsakoglu Y, Kunchok T, Hoffmann FA, Parisi B, Rincon M, Vander Heiden MG, Bosenberg M, Hargreaves DC, Kaech SM, Shadel GS. Manipulating mitochondrial electron flow enhances tumor immunogenicity. Science. 2023 09 22; 381(6664):1316-1323.
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Simpson DM, Chuong EB. Genetic Knockout of TE Insertions by CRISPR-Cas9. Methods Mol Biol. 2023; 2607:369-379.
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Lane BM, Chryst-Stangl M, Wu G, Shalaby M, El Desoky S, Middleton CC, Huggins K, Sood A, Ochoa A, Malone AF, Vancini R, Miller SE, Hall G, Kim SY, Howell DN, Kari JA, Gbadegesin R. Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis. JCI Insight. 2022 01 25; 7(2).
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Theodoridi A, Dinarello A, Badenetti L, Pavlidis M, Dalla Valle L, Tsalafouta A. Knockout of the hsd11b2 Gene Extends the Cortisol Stress Response in Both Zebrafish Larvae and Adults. Int J Mol Sci. 2021 Nov 20; 22(22).
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