 Connection
Philip Reigan to Thymidine Phosphorylase
This is a "connection" page, showing publications Philip Reigan has written about Thymidine Phosphorylase.
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Connection Strength |
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2.455 |
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Warfield BM, Reigan P. Multifunctional role of thymidine phosphorylase in cancer. Trends Cancer. 2022 06; 8(6):482-493.
Score: 0.794
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Warfield BM, Matheson CJ, McArthur DG, Backos DS, Reigan P. Evaluation of Thymidine Phosphorylase Inhibitors in Glioblastoma and Their Capacity for Temozolomide Potentiation. ACS Chem Neurosci. 2021 09 15; 12(18):3477-3486.
Score: 0.769
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Reigan P, Gbaj A, Stratford IJ, Bryce RA, Freeman S. Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors. Eur J Med Chem. 2008 Jun; 43(6):1248-60.
Score: 0.290
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Reigan P, Edwards PN, Gbaj A, Cole C, Barry ST, Page KM, Ashton SE, Luke RW, Douglas KT, Stratford IJ, Jaffar M, Bryce RA, Freeman S. Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs. J Med Chem. 2005 Jan 27; 48(2):392-402.
Score: 0.243
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Reigan P, Gbaj A, Chinje E, Stratford IJ, Douglas KT, Freeman S. Synthesis and enzymatic evaluation of xanthine oxidase-activated prodrugs based on inhibitors of thymidine phosphorylase. Bioorg Med Chem Lett. 2004 Nov 01; 14(21):5247-50.
Score: 0.239
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Gbaj A, Edwards PN, Reigan P, Freeman S, Jaffar M, Douglas KT. Thymidine phosphorylase from Escherichia coli: tight-binding inhibitors as enzyme active-site titrants. J Enzyme Inhib Med Chem. 2006 Feb; 21(1):69-73.
Score: 0.065
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Cole C, Reigan P, Gbaj A, Edwards PN, Douglas KT, Stratford IJ, Freeman S, Jaffar M. Potential tumor-selective nitroimidazolylmethyluracil prodrug derivatives: inhibitors of the angiogenic enzyme thymidine phosphorylase. J Med Chem. 2003 Jan 16; 46(2):207-9.
Score: 0.053
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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