 Enzyme Assays
"Enzyme Assays" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Methods used to measure the relative activity of a specific enzyme or its concentration in solution. Typically an enzyme substrate is added to a buffer solution containing enzyme and the rate of conversion of substrate to product is measured under controlled conditions. Many classical enzymatic assay methods involve the use of synthetic colorimetric substrates and measuring the reaction rates using a spectrophotometer.
| Descriptor ID |
D057075
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| MeSH Number(s) |
E05.196.427
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| Concept/Terms |
Enzyme Assays- Enzyme Assays
- Assay, Enzyme
- Assays, Enzyme
- Enzyme Assay
- Enzymatic Assays
- Assay, Enzymatic
- Assays, Enzymatic
- Enzymatic Assay
Indirect Enzyme Assays- Indirect Enzyme Assays
- Assay, Indirect Enzyme
- Assays, Indirect Enzyme
- Enzyme Assay, Indirect
- Enzyme Assays, Indirect
- Indirect Enzyme Assay
- Indirect Enzymatic Assays
- Assay, Indirect Enzymatic
- Assays, Indirect Enzymatic
- Enzymatic Assay, Indirect
- Enzymatic Assays, Indirect
- Indirect Enzymatic Assay
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Below are MeSH descriptors whose meaning is more general than "Enzyme Assays".
Below are MeSH descriptors whose meaning is more specific than "Enzyme Assays".
This graph shows the total number of publications written about "Enzyme Assays" by people in this website by year, and whether "Enzyme Assays" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 1 | 2 | | 2018 | 0 | 2 | 2 | | 2020 | 1 | 1 | 2 | | 2021 | 0 | 4 | 4 |
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Below are the most recent publications written about "Enzyme Assays" by people in Profiles.
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Canal B, Fujisawa R, McClure AW, Deegan TD, Wu M, Ulferts R, Weissmann F, Drury LS, Bertolin AP, Zeng J, Beale R, Howell M, Labib K, Diffley JFX. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease. Biochem J. 2021 07 16; 478(13):2465-2479.
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Canal B, McClure AW, Curran JF, Wu M, Ulferts R, Weissmann F, Zeng J, Bertolin AP, Milligan JC, Basu S, Drury LS, Deegan TD, Fujisawa R, Roberts EL, Basier C, Labib K, Beale R, Howell M, Diffley JFX. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease. Biochem J. 2021 07 16; 478(13):2445-2464.
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Basu S, Mak T, Ulferts R, Wu M, Deegan T, Fujisawa R, Tan KW, Lim CT, Basier C, Canal B, Curran JF, Drury LS, McClure AW, Roberts EL, Weissmann F, Zeisner TU, Beale R, Cowling VH, Howell M, Labib K, Diffley JFX. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase. Biochem J. 2021 07 16; 478(13):2481-2497.
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Fohner AE, Dalton R, Skagen K, Jackson K, Claw KG, Hopkins SE, Robinson R, Khan BA, Prasad B, Schuetz EG, Nickerson DA, Thornton TA, Dillard DA, Boyer BB, Thummel KE, Woodahl EL. Characterization of CYP3A pharmacogenetic variation in American Indian and Alaska Native communities, targeting CYP3A4*1G allele function. Clin Transl Sci. 2021 Jul; 14(4):1292-1302.
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Iwasaki RS, Batey RT. SPRINT: a Cas13a-based platform for detection of small molecules. Nucleic Acids Res. 2020 09 25; 48(17):e101.
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Palmer AE, C Hammond M. Editorial overview: Molecular imaging. Curr Opin Chem Biol. 2020 08; 57:A5-A7.
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Wlodarchak N, Teachout N, Beczkiewicz J, Procknow R, Schaenzer AJ, Satyshur K, Pavelka M, Zuercher W, Drewry D, Sauer JD, Striker R. In Silico Screen and Structural Analysis Identifies Bacterial Kinase Inhibitors which Act with ?-Lactams To Inhibit Mycobacterial Growth. Mol Pharm. 2018 11 05; 15(11):5410-5426.
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Van Damme T, Pang X, Guillemyn B, Gulberti S, Syx D, De Rycke R, Kaye O, de Die-Smulders CEM, Pfundt R, Kariminejad A, Nampoothiri S, Pierquin G, Bulk S, Larson AA, Chatfield KC, Simon M, Legrand A, Gerard M, Symoens S, Fournel-Gigleux S, Malfait F. Biallelic B3GALT6 mutations cause spondylodysplastic Ehlers-Danlos syndrome. Hum Mol Genet. 2018 10 15; 27(20):3475-3487.
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Matheson CJ, Casalvieri KA, Backos DS, Reigan P. Development of Potent Pyrazolopyrimidinone-Based WEE1 Inhibitors with Limited Single-Agent Cytotoxicity for Cancer Therapy. ChemMedChem. 2018 08 20; 13(16):1681-1694.
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Shin HK, Grahame G, McCandless SE, Kerr DS, Bedoyan JK. Enzymatic testing sensitivity, variability and practical diagnostic algorithm for pyruvate dehydrogenase complex (PDC) deficiency. Mol Genet Metab. 2017 11; 122(3):61-66.
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