NF-kappa B p50 Subunit
"NF-kappa B p50 Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A component of NF-kappa B transcription factor. It is proteolytically processed from NF-kappa B p105 precursor protein and is capable of forming dimeric complexes with itself or with TRANSCRIPTION FACTOR RELA. It regulates expression of GENES involved in immune and inflammatory responses.
Descriptor ID |
D052002
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MeSH Number(s) |
D12.776.260.600.124 D12.776.660.600.124 D12.776.930.600.124
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Concept/Terms |
NF-kappa B p50 Subunit- NF-kappa B p50 Subunit
- NF kappa B p50 Subunit
- NFKB1 Transcription Factor
- Transcription Factor, NFKB1
- NF-kappa B p50
- NF kappa B p50
- p50, NF-kappa B
- NF-kappaB 50-kDa
- NF kappaB 50 kDa
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Below are MeSH descriptors whose meaning is more general than "NF-kappa B p50 Subunit".
Below are MeSH descriptors whose meaning is more specific than "NF-kappa B p50 Subunit".
This graph shows the total number of publications written about "NF-kappa B p50 Subunit" by people in this website by year, and whether "NF-kappa B p50 Subunit" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 0 | 2 | 2 | 2006 | 0 | 1 | 1 | 2007 | 1 | 1 | 2 | 2011 | 0 | 1 | 1 | 2013 | 1 | 0 | 1 | 2014 | 1 | 0 | 1 | 2018 | 2 | 0 | 2 | 2019 | 0 | 1 | 1 | 2020 | 0 | 2 | 2 | 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "NF-kappa B p50 Subunit" by people in Profiles.
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Verma M, Verma D, Sripada AS, Sirohi K, Varma R, Sahu A, Alam R. NF?B1 inhibits memory formation and supports effector function of ILC2s in memory-driven asthma. Front Immunol. 2023; 14:1217776.
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McCarthy WC, Sherlock LG, Grayck MR, Zheng L, Lacayo OA, Solar M, Orlicky DJ, Dobrinskikh E, Wright CJ. Innate Immune Zonation in the Liver: NF-?B (p50) Activation and C-Reactive Protein Expression in Response to Endotoxemia Are Zone Specific. J Immunol. 2023 05 01; 210(9):1372-1385.
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Zarate MA, Nguyen LM, De Dios RK, Zheng L, Wright CJ. Maturation of the Acute Hepatic TLR4/NF-?B Mediated Innate Immune Response Is p65 Dependent in Mice. Front Immunol. 2020; 11:1892.
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Wright CJ, Cari EL, Sandoval J, Bales E, Sam PK, Zarate MA, Polotsky AJ, Kallen AN, Johnson J. Control of Murine Primordial Follicle Growth Activation by I?B/NF?B Signaling. Reprod Sci. 2020 11; 27(11):2063-2074.
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Pollyea DA, Harris C, Rabe JL, Hedin BR, De Arras L, Katz S, Wheeler E, Bejar R, Walter MJ, Jordan CT, Pietras EM, Alper S. Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling. Haematologica. 2019 09; 104(9):e388-e392.
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McKenna S, Burey T, Sandoval J, Nguyen L, Castro O, Gudipati S, Gonzalez J, El Kasmi KC, Wright CJ. Immunotolerant p50/NF?B Signaling and Attenuated Hepatic IFN? Expression Increases Neonatal Sensitivity to Endotoxemia. Front Immunol. 2018; 9:2210.
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Dodson RB, Powers KN, Gien J, Rozance PJ, Seedorf G, Astling D, Jones K, Crombleholme TM, Abman SH, Alvira CM. Intrauterine growth restriction decreases NF-?B signaling in fetal pulmonary artery endothelial cells of fetal sheep. Am J Physiol Lung Cell Mol Physiol. 2018 09 01; 315(3):L348-L359.
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Brown JD, Lin CY, Duan Q, Griffin G, Federation A, Paranal RM, Bair S, Newton G, Lichtman A, Kung A, Yang T, Wang H, Luscinskas FW, Croce K, Bradner JE, Plutzky J. NF-?B directs dynamic super enhancer formation in inflammation and atherogenesis. Mol Cell. 2014 Oct 23; 56(2):219-231.
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Chen W, Roncal-Jimenez C, Lanaspa M, Gerard S, Chonchol M, Johnson RJ, Jalal D. Uric acid suppresses 1 alpha hydroxylase in vitro and in vivo. Metabolism. 2014 Jan; 63(1):150-60.
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Zhou X, Shapiro L, Fellingham G, Willardson BM, Burton GF. HIV replication in CD4+ T lymphocytes in the presence and absence of follicular dendritic cells: inhibition of replication mediated by a-1-antitrypsin through altered I?Ba ubiquitination. J Immunol. 2011 Mar 01; 186(5):3148-55.
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