 Synaptosomes
"Synaptosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Pinched-off nerve endings and their contents of vesicles and cytoplasm together with the attached subsynaptic area of the membrane of the post-synaptic cell. They are largely artificial structures produced by fractionation after selective centrifugation of nervous tissue homogenates.
| Descriptor ID |
D013574
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| MeSH Number(s) |
A11.284.835.859
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synaptosomes".
Below are MeSH descriptors whose meaning is more specific than "Synaptosomes".
This graph shows the total number of publications written about "Synaptosomes" by people in this website by year, and whether "Synaptosomes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2009 | 2 | 0 | 2 | | 2012 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Synaptosomes" by people in Profiles.
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Caffino L, Piva A, Mottarlini F, Di Chio M, Giannotti G, Chiamulera C, Fumagalli F. Ketamine Self-Administration Elevates aCaMKII Autophosphorylation in Mood and Reward-Related Brain Regions in Rats. Mol Neurobiol. 2018 Jul; 55(7):5453-5461.
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Vendramin Pasquetti M, Meier L, Loureiro S, Ganzella M, Junges B, Barbieri Caus L, Umpierrez Amaral A, Koeller DM, Goodman S, Woontner M, Gomes de Souza DO, Wajner M, Calcagnotto ME. Impairment of GABAergic system contributes to epileptogenesis in glutaric acidemia type I. Epilepsia. 2017 10; 58(10):1771-1781.
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McClure-Begley TD, Grady SR, Marks MJ, Collins AC, Stitzel JA. Presynaptic GABAB autoreceptor regulation of nicotinic acetylcholine receptor mediated [(3)H]-GABA release from mouse synaptosomes. Biochem Pharmacol. 2014 Sep 01; 91(1):87-96.
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O'Neill HC, Laverty DC, Patzlaff NE, Cohen BN, Fonck C, McKinney S, McIntosh JM, Lindstrom JM, Lester HA, Grady SR, Marks MJ. Mice expressing the ADNFLE valine 287 leucine mutation of the ?2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function. Pharmacol Biochem Behav. 2013 Jan; 103(3):603-21.
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Ryan K, Backos DS, Reigan P, Patel M. Post-translational oxidative modification and inactivation of mitochondrial complex I in epileptogenesis. J Neurosci. 2012 Aug 15; 32(33):11250-8.
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Cortese GP, Barrientos RM, Maier SF, Patterson SL. Aging and a peripheral immune challenge interact to reduce mature brain-derived neurotrophic factor and activation of TrkB, PLCgamma1, and ERK in hippocampal synaptoneurosomes. J Neurosci. 2011 Mar 16; 31(11):4274-9.
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Marks MJ, Meinerz NM, Brown RW, Collins AC. 86Rb+ efflux mediated by alpha4beta2*-nicotinic acetylcholine receptors with high and low-sensitivity to stimulation by acetylcholine display similar agonist-induced desensitization. Biochem Pharmacol. 2010 Oct 15; 80(8):1238-51.
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Gerencser AA, Neilson A, Choi SW, Edman U, Yadava N, Oh RJ, Ferrick DA, Nicholls DG, Brand MD. Quantitative microplate-based respirometry with correction for oxygen diffusion. Anal Chem. 2009 Aug 15; 81(16):6868-78.
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Singh OV, Yaster M, Xu JT, Guan Y, Guan X, Dharmarajan AM, Raja SN, Zeitlin PL, Tao YX. Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury. Proteomics. 2009 Mar; 9(5):1241-53.
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McClure-Begley TD, King NM, Collins AC, Stitzel JA, Wehner JM, Butt CM. Acetylcholine-stimulated [3H]GABA release from mouse brain synaptosomes is modulated by alpha4beta2 and alpha4alpha5beta2 nicotinic receptor subtypes. Mol Pharmacol. 2009 Apr; 75(4):918-26.
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