Synaptosomes
"Synaptosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Pinched-off nerve endings and their contents of vesicles and cytoplasm together with the attached subsynaptic area of the membrane of the post-synaptic cell. They are largely artificial structures produced by fractionation after selective centrifugation of nervous tissue homogenates.
Descriptor ID |
D013574
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MeSH Number(s) |
A11.284.835.859
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synaptosomes".
Below are MeSH descriptors whose meaning is more specific than "Synaptosomes".
This graph shows the total number of publications written about "Synaptosomes" by people in this website by year, and whether "Synaptosomes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 | 2002 | 1 | 0 | 1 | 2003 | 0 | 1 | 1 | 2004 | 0 | 2 | 2 | 2005 | 0 | 1 | 1 | 2009 | 2 | 2 | 4 | 2010 | 0 | 2 | 2 | 2011 | 0 | 1 | 1 | 2012 | 1 | 3 | 4 | 2013 | 0 | 1 | 1 | 2014 | 1 | 1 | 2 |
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Below are the most recent publications written about "Synaptosomes" by people in Profiles.
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Caffino L, Piva A, Mottarlini F, Di Chio M, Giannotti G, Chiamulera C, Fumagalli F. Ketamine Self-Administration Elevates aCaMKII Autophosphorylation in Mood and Reward-Related Brain Regions in Rats. Mol Neurobiol. 2018 Jul; 55(7):5453-5461.
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Vendramin Pasquetti M, Meier L, Loureiro S, Ganzella M, Junges B, Barbieri Caus L, Umpierrez Amaral A, Koeller DM, Goodman S, Woontner M, Gomes de Souza DO, Wajner M, Calcagnotto ME. Impairment of GABAergic system contributes to epileptogenesis in glutaric acidemia type I. Epilepsia. 2017 10; 58(10):1771-1781.
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McClure-Begley TD, Grady SR, Marks MJ, Collins AC, Stitzel JA. Presynaptic GABAB autoreceptor regulation of nicotinic acetylcholine receptor mediated [(3)H]-GABA release from mouse synaptosomes. Biochem Pharmacol. 2014 Sep 01; 91(1):87-96.
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Marks MJ, Grady SR, Salminen O, Paley MA, Wageman CR, McIntosh JM, Whiteaker P. a6?2*-subtype nicotinic acetylcholine receptors are more sensitive than a4?2*-subtype receptors to regulation by chronic nicotine administration. J Neurochem. 2014 Jul; 130(2):185-98.
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Soll LG, Grady SR, Salminen O, Marks MJ, Tapper AR. A role for a4(non-a6)* nicotinic acetylcholine receptors in motor behavior. Neuropharmacology. 2013 Oct; 73:19-30.
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O'Neill HC, Laverty DC, Patzlaff NE, Cohen BN, Fonck C, McKinney S, McIntosh JM, Lindstrom JM, Lester HA, Grady SR, Marks MJ. Mice expressing the ADNFLE valine 287 leucine mutation of the ?2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function. Pharmacol Biochem Behav. 2013 Jan; 103(3):603-21.
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Ryan K, Backos DS, Reigan P, Patel M. Post-translational oxidative modification and inactivation of mitochondrial complex I in epileptogenesis. J Neurosci. 2012 Aug 15; 32(33):11250-8.
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McClure-Begley TD, Wageman CR, Grady SR, Marks MJ, McIntosh JM, Collins AC, Whiteaker P. A novel a-conotoxin MII-sensitive nicotinic acetylcholine receptor modulates [(3) H]-GABA release in the superficial layers of the mouse superior colliculus. J Neurochem. 2012 Jul; 122(1):48-57.
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Grady SR, Wageman CR, Patzlaff NE, Marks MJ. Low concentrations of nicotine differentially desensitize nicotinic acetylcholine receptors that include a5 or a6 subunits and that mediate synaptosomal neurotransmitter release. Neuropharmacology. 2012 Apr; 62(5-6):1935-43.
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McGranahan TM, Patzlaff NE, Grady SR, Heinemann SF, Booker TK. a4?2 nicotinic acetylcholine receptors on dopaminergic neurons mediate nicotine reward and anxiety relief. J Neurosci. 2011 Jul 27; 31(30):10891-902.
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