Binding, Competitive
"Binding, Competitive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The interaction of two or more substrates or ligands with the same binding site. The displacement of one by the other is used in quantitative and selective affinity measurements.
Descriptor ID |
D001667
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MeSH Number(s) |
E05.196.080 G02.111.084 G02.111.570.120.309
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Binding, Competitive".
Below are MeSH descriptors whose meaning is more specific than "Binding, Competitive".
This graph shows the total number of publications written about "Binding, Competitive" by people in this website by year, and whether "Binding, Competitive" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 3 | 3 | 1995 | 0 | 8 | 8 | 1996 | 0 | 14 | 14 | 1997 | 0 | 5 | 5 | 1998 | 0 | 2 | 2 | 1999 | 0 | 2 | 2 | 2000 | 0 | 4 | 4 | 2001 | 0 | 11 | 11 | 2002 | 0 | 5 | 5 | 2003 | 1 | 2 | 3 | 2004 | 0 | 4 | 4 | 2005 | 0 | 3 | 3 | 2006 | 0 | 2 | 2 | 2008 | 0 | 5 | 5 | 2009 | 0 | 3 | 3 | 2010 | 0 | 2 | 2 | 2011 | 0 | 2 | 2 | 2012 | 0 | 4 | 4 | 2013 | 0 | 2 | 2 | 2014 | 1 | 2 | 3 | 2015 | 0 | 4 | 4 | 2018 | 0 | 2 | 2 | 2019 | 0 | 4 | 4 | 2020 | 0 | 3 | 3 |
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Below are the most recent publications written about "Binding, Competitive" by people in Profiles.
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Youmans DT, Gooding AR, Dowell RD, Cech TR. Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells. Mol Cell. 2021 02 04; 81(3):488-501.e9.
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Link KG, Stobb MT, Monroe DM, Fogelson AL, Neeves KB, Sindi SS, Leiderman K. Computationally Driven Discovery in Coagulation. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):79-86.
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Holmes ZE, Hamilton DJ, Hwang T, Parsonnet NV, Rinn JL, Wuttke DS, Batey RT. The Sox2 transcription factor binds RNA. Nat Commun. 2020 04 14; 11(1):1805.
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Abraham AD, Esquer H, Zhou Q, Tomlinson N, Hamill BD, Abbott JM, Li L, Pike LA, Rinaldetti S, Ramirez DA, Lunghofer PJ, Gomez JD, Schaack J, Nemkov T, D'Alessandro A, Hansen KC, Gustafson DL, Messersmith WA, LaBarbera DV. Drug Design Targeting T-Cell Factor-Driven Epithelial-Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer. J Med Chem. 2019 11 27; 62(22):10182-10203.
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Duan T, Tradtrantip L, Phuan PW, Bennett JL, Verkman AS. Affinity-matured 'aquaporumab' anti-aquaporin-4 antibody for therapy of seropositive neuromyelitis optica spectrum disorders. Neuropharmacology. 2020 01 01; 162:107827.
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Parsonnet NV, Lammer NC, Holmes ZE, Batey RT, Wuttke DS. The glucocorticoid receptor DNA-binding domain recognizes RNA hairpin structures with high affinity. Nucleic Acids Res. 2019 09 05; 47(15):8180-8192.
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Zhang Y, Ahn J, Green KJ, Vann KR, Black J, Brooke CB, Kutateladze TG. MORC3 Is a Target of the Influenza A Viral Protein NS1. Structure. 2019 06 04; 27(6):1029-1033.e3.
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Kuzmak A, Carmali S, von Lieres E, Russell AJ, Kondrat S. Can enzyme proximity accelerate cascade reactions? Sci Rep. 2019 01 24; 9(1):455.
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Yang J, Xu J, Gonzalez R, Lindner T, Kratochwil C, Miao Y. 68Ga-DOTA-GGNle-CycMSHhex targets the melanocortin-1 receptor for melanoma imaging. Sci Transl Med. 2018 11 07; 10(466).
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Plautz WE, Sekhar Pilli VS, Cooley BC, Chattopadhyay R, Westmark PR, Getz T, Paul D, Bergmeier W, Sheehan JP, Majumder R. Anticoagulant Protein S Targets the Factor IXa Heparin-Binding Exosite to Prevent Thrombosis. Arterioscler Thromb Vasc Biol. 2018 04; 38(4):816-828.
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