 Endoplasmic Reticulum Stress
"Endoplasmic Reticulum Stress" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Various physiological or molecular disturbances that impair ENDOPLASMIC RETICULUM function. It triggers many responses, including UNFOLDED PROTEIN RESPONSE, which may lead to APOPTOSIS; and AUTOPHAGY.
| Descriptor ID |
D059865
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| MeSH Number(s) |
G04.434
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| Concept/Terms |
Endoplasmic Reticulum Stress- Endoplasmic Reticulum Stress
- Endoplasmic Reticulum Stresses
- Reticulum Stress, Endoplasmic
- Reticulum Stresses, Endoplasmic
- Stresses, Endoplasmic Reticulum
- Stress, Endoplasmic Reticulum
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Below are MeSH descriptors whose meaning is more general than "Endoplasmic Reticulum Stress".
Below are MeSH descriptors whose meaning is more specific than "Endoplasmic Reticulum Stress".
This graph shows the total number of publications written about "Endoplasmic Reticulum Stress" by people in this website by year, and whether "Endoplasmic Reticulum Stress" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 | | 2012 | 2 | 2 | 4 | | 2013 | 2 | 3 | 5 | | 2014 | 4 | 2 | 6 | | 2015 | 3 | 3 | 6 | | 2016 | 4 | 1 | 5 | | 2017 | 2 | 6 | 8 | | 2018 | 2 | 2 | 4 | | 2019 | 4 | 2 | 6 | | 2020 | 3 | 3 | 6 | | 2021 | 1 | 4 | 5 | | 2023 | 0 | 2 | 2 | | 2024 | 1 | 1 | 2 | | 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Endoplasmic Reticulum Stress" by people in Profiles.
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Hansen MS, Pokharel P, Piganelli J, Sussel L. The Chicken or the Egg Dilemma: Understanding the Interplay between the Immune System and the ? Cell in Type 1 Diabetes. Cold Spring Harb Perspect Med. 2025 Apr 01; 15(4).
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Schiavon A, Saba L, Evaristo C, Petiti J, Pignochino Y, Ferrero G, Giordano G, Tucciarello C, Puglisi S, Reimondo G, Terzolo M, Lo Iacono M. Mitotane activates ATF4/ATF3 axis triggering endoplasmic reticulum stress in adrenocortical carcinoma cells. Biomed Pharmacother. 2025 Mar; 184:117917.
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Oguh AU, Haemmerle MW, Sen S, Rozo AV, Shrestha S, Cartailler JP, Fazelinia H, Ding H, Preza S, Yang J, Yang X, Sussel L, Alvarez-Dominguez JR, Doliba N, Spruce LA, Arrojo E Drigo R, Stoffers DA. E3 ligase substrate adaptor SPOP fine-tunes the UPR of pancreatic ? cells. Genes Dev. 2025 Feb 03; 39(3-4):261-279.
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Murthy A, Rodriguez LR, Dimopoulos T, Bui S, Iyer S, Chavez K, Tomer Y, Abraham V, Cooper C, Renner DM, Katzen JB, Bentley ID, Ghadiali SN, Englert JA, Weiss SR, Beers MF. Activation of alveolar epithelial ER stress by ?-coronavirus infection disrupts surfactant homeostasis in mice: implications for COVID-19 respiratory failure. Am J Physiol Lung Cell Mol Physiol. 2024 Aug 01; 327(2):L232-L249.
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Cooley JC, Redente EF. Getting the Timing Right: Controlling BCL-2 Inhibition as an Antifibrotic Therapy. Am J Respir Cell Mol Biol. 2024 Apr; 70(4):231-232.
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Iyer S, Adams DJ. Bone and the Unfolded Protein Response: In Sickness and in Health. Calcif Tissue Int. 2023 07; 113(1):96-109.
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Subramanian K, Paul S, Libby A, Patterson J, Arterbery A, Knight J, Castaldi C, Wang G, Avitzur Y, Martinez M, Lobritto S, Deng Y, Geliang G, Kroemer A, Fishbein T, Mason A, Dominguez-Villar M, Mariappan M, Ekong UD. HERV1-env Induces Unfolded Protein Response Activation in Autoimmune Liver Disease: A Potential Mechanism for Regulatory T Cell Dysfunction. J Immunol. 2023 03 15; 210(6):732-744.
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Dobrinskikh E, Hennessy CE, Kurche JS, Kim E, Estrella AM, Cardwell J, Yang IV, Schwartz DA. Epithelial Endoplasmic Reticulum Stress Enhances the Risk of Muc5b-associated Lung Fibrosis. Am J Respir Cell Mol Biol. 2023 01; 68(1):62-74.
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Sweet LA, Kuss-Duerkop SK, Keestra-Gounder AM. IRE1a-Driven Inflammation Promotes Clearance of Citrobacter rodentium Infection. Infect Immun. 2022 01 25; 90(1):e0048121.
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Shiozaki Y, Miyazaki-Anzai S, Keenan AL, Miyazaki M. MEF2D-NR4A1-FAM134B2-mediated reticulophagy contributes to amino acid homeostasis. Autophagy. 2022 05; 18(5):1049-1061.
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