Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution
Menu

Contact Us
If you have any questions or feedback please contact us.

Shaodong Dai

TitleProfessor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOP-Administration
Phone303/724-3276

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Shang G, Yang M, Li M, Ma L, Liu Y, Ma J, Chen Y, Wang X, Fan S, Xie M, Wu W, Dai S, Chen Z. Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A. Int J Mol Sci. 2024 Jan 05; 25(2). PMID: 38255759.
      View in: PubMed
    2. Liu Y, Ma L, Li M, Tian Z, Yang M, Wu X, Wang X, Shang G, Xie M, Chen Y, Liu X, Jiang L, Wu W, Xu C, Xia L, Li G, Dai S, Chen Z. Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation. Nucleic Acids Res. 2023 02 22; 51(3):1443-1457. PMID: 36651297.
      View in: PubMed
    3. Li W, Li R, Wang Y, Zhang Y, Tomar MS, Dai S. Calcitonin gene-related peptide is a potential autoantigen for CD4 T cells in type 1 diabetes. Front Immunol. 2022; 13:951281. PMID: 36189304.
      View in: PubMed
    4. Li W, Zhang Y, Li R, Wang Y, Chen L, Dai S. A Novel Tolerogenic Antibody Targeting Disulfide-Modified Autoantigen Effectively Prevents Type 1 Diabetes in NOD Mice. Front Immunol. 2022; 13:877022. PMID: 36032077.
      View in: PubMed
    5. Wang Y, Tsitsiklis A, Devoe S, Gao W, Chu HH, Zhang Y, Li W, Wong WK, Deane CM, Neau D, Slansky JE, Thomas PG, Robey EA, Dai S. Peptide Centric V? Specific Germline Contacts Shape a Specialist T Cell Response. Front Immunol. 2022; 13:847092. PMID: 35967379.
      View in: PubMed
    6. Zuo D, Chen Y, Cai JP, Yuan HY, Wu JQ, Yin Y, Xie JW, Lin JM, Luo J, Feng Y, Ge LJ, Zhou J, Quinn RJ, Zhao SJ, Tong X, Jin DY, Yuan S, Dai SX, Xu M. A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicron in vivo. Protein Cell. 2023 01; 14(1):37-50. PMID: 36726760.
      View in: PubMed
    7. Gaikwad H, Li Y, Wang G, Li R, Dai S, Rester C, Kedl R, Saba L, Banda NK, Scheinman RI, Patrick C, Mallela KMG, Moghimi SM, Simberg D. Antibody-Dependent Complement Responses toward SARS-CoV-2 Receptor-Binding Domain Immobilized on "Pseudovirus-like" Nanoparticles. ACS Nano. 2022 May 04. PMID: 35507641.
      View in: PubMed
    8. Li WX, Tong X, Yang PP, Zheng Y, Liang JH, Li GH, Liu D, Guan DG, Dai SX. Screening of antibacterial compounds with novel structure from the FDA approved drugs using machine learning methods. Aging (Albany NY). 2022 02 12; 14(3):1448-1472. PMID: 35150482.
      View in: PubMed
    9. Ma L, Lu H, Tian Z, Yang M, Ma J, Shang G, Liu Y, Xie M, Wang G, Wu W, Zhang Z, Dai S, Chen Z. Structural insights into the interactions and epigenetic functions of human nucleic acid repair protein ALKBH6. J Biol Chem. 2022 03; 298(3):101671. PMID: 35120926.
      View in: PubMed
    10. Tong L, Dai SX, Kong DJ, Yang PP, Tong X, Tong XR, Bi XX, Su Y, Zhao YQ, Liu ZC. The genome of medicinal leech (Whitmania pigra) and comparative genomic study for exploration of bioactive ingredients. BMC Genomics. 2022 Jan 24; 23(1):76. PMID: 35073842.
      View in: PubMed
    11. Wang X, Hu C, Ye W, Wang J, Dong X, Xu J, Li X, Zhang M, Lu H, Zhang F, Wu W, Dai S, Wang HW, Chen Z. Structure of Rift Valley Fever Virus RNA-Dependent RNA Polymerase. J Virol. 2022 02 09; 96(3):e0171321. PMID: 34787453.
      View in: PubMed
    12. Greaves SA, Ravindran A, Santos RG, Chen L, Falta MT, Wang Y, Mitchell AM, Atif SM, Mack DG, Tinega AN, Maier LA, Dai S, Pinilla C, Grunewald J, Fontenot AP. CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope. J Exp Med. 2021 10 04; 218(10). PMID: 34410304.
      View in: PubMed
    13. Wei P, Jordan KR, Buhrman JD, Lei J, Deng H, Marrack P, Dai S, Kappler JW, Slansky JE, Yin L. Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer. Proc Natl Acad Sci U S A. 2021 06 08; 118(23). PMID: 34074778.
      View in: PubMed
    14. Chen L, Zhang Y, Pacheco K, Dai S. The T Cell Repertoires from Nickel Sensitized Joint Implant Failure Patients. Int J Mol Sci. 2021 Feb 28; 22(5). PMID: 33670995.
      View in: PubMed
    15. Kamran M, Liang J, Liu B, Li Y, Gao J, Keating A, Mohamed F, Dai S, Reinhardt R, Jiong Y, Wu Z, Huang H. The Clusters of Transcription Factors NFATC2, STAT5, GATA2, AP1, RUNX1 and EGR2 Binding Sites at the Induced Il13 Enhancers Mediate Il13 Gene Transcription in Response to Antigenic Stimulation. J Immunol. 2020 12 15; 205(12):3311-3318. PMID: 33188077.
      View in: PubMed
    16. Zhang Y, Anderson KM, Freed BM, Dai S, Pacheco KA. HLA-DR53 (DRB4*01) associates with nickel sensitization. Ann Allergy Asthma Immunol. 2020 11; 125(5):614-616. PMID: 32693207.
      View in: PubMed
    17. Tsitsiklis A, Bangs DJ, Lutes LK, Chan SW, Geiger KM, Modzelewski AJ, Labarta-Bajo L, Wang Y, Zuniga EI, Dai S, Robey EA. An Unusual MHC Molecule Generates Protective CD8+ T Cell Responses to Chronic Infection. Front Immunol. 2020; 11:1464. PMID: 32733483.
      View in: PubMed
    18. Tian Z, Li X, Li M, Wu W, Zhang M, Tang C, Li Z, Liu Y, Chen Z, Yang M, Ma L, Caba C, Tong Y, Lam HM, Dai S, Chen Z. Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms. Cell Discov. 2020; 6:17. PMID: 32257379.
      View in: PubMed
    19. Li BX, Zhang H, Liu Y, Li Y, Zheng JJ, Li WX, Feng K, Sun M, Dai SX. Novel pathways of HIV latency reactivation revealed by integrated analysis of transcriptome and target profile of bryostatin. Sci Rep. 2020 02 26; 10(1):3511. PMID: 32103135.
      View in: PubMed
    20. Cepeda JR, Sekhar NS, Han J, Xiong W, Zhang N, Yu L, Dai S, Davidson HW, Kappler JW, An Z, Zhang L. A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice. MAbs. 2020 Jan-Dec; 12(1):1836714. PMID: 33151102.
      View in: PubMed
    21. Wang Y, Sosinowski T, Novikov A, Crawford F, White J, Jin N, Liu Z, Zou J, Neau D, Davidson HW, Nakayama M, Kwok WW, Gapin L, Marrack P, Kappler JW, Dai S. How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes. Sci Immunol. 2019 04 05; 4(34). PMID: 30952805.
      View in: PubMed
    22. Kim JS, Liu L, Fitzsimmons LF, Wang Y, Crawford MA, Mastrogiovanni M, Trujillo M, Till JKA, Radi R, Dai S, V?zquez-Torres A. DksA-DnaJ redox interactions provide a signal for the activation of bacterial RNA polymerase. Proc Natl Acad Sci U S A. 2018 12 11; 115(50):E11780-E11789. PMID: 30429329.
      View in: PubMed
    23. Lee S, Wang C, Liu H, Xiong J, Jiji R, Hong X, Yan X, Chen Z, Hammel M, Wang Y, Dai S, Wang J, Jiang C, Zhang G. Hydrogen bonds are a primary driving force for de novo protein folding. Corrigendum. Acta Crystallogr D Struct Biol. 2018 04 01; 74(Pt 4):380. PMID: 29652265.
      View in: PubMed
    24. Liu H, Wang C, Lee S, Ning F, Wang Y, Zhang Q, Chen Z, Zang J, Nix J, Dai S, Marrack P, Hagman J, Kappler J, Zhang G. Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. Sci Rep. 2018 02 19; 8(1):3275. PMID: 29459673.
      View in: PubMed
    25. Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):162-167. PMID: 29255035.
      View in: PubMed
    26. Lee S, Wang C, Liu H, Xiong J, Jiji R, Hong X, Yan X, Chen Z, Hammel M, Wang Y, Dai S, Wang J, Jiang C, Zhang G. Hydrogen bonds are a primary driving force for de novo protein folding. Acta Crystallogr D Struct Biol. 2017 Dec 01; 73(Pt 12):955-969. PMID: 29199976.
      View in: PubMed
    27. Salinas G, Gao W, Wang Y, Bonilla M, Yu L, Novikov A, Virginio VG, Ferreira HB, Vieites M, Gladyshev VN, Gambino D, Dai S. The Enzymatic and Structural Basis for Inhibition of Echinococcus granulosus Thioredoxin Glutathione Reductase by Gold(I). Antioxid Redox Signal. 2017 Dec 20; 27(18):1491-1504. PMID: 28463568.
      View in: PubMed
    28. Zhang Y, Wang Y, Anderson K, Novikov A, Liu Z, Pacheco K, Dai S. Using DR52c/Ni2+ mimotope tetramers to detect Ni2+ reactive CD4+ T cells in patients with joint replacement failure. Toxicol Appl Pharmacol. 2017 09 15; 331:69-75. PMID: 28554661.
      View in: PubMed
    29. Fontenot AP, Falta MT, Kappler JW, Dai S, McKee AS. Beryllium-Induced Hypersensitivity: Genetic Susceptibility and Neoantigen Generation. J Immunol. 2016 Jan 01; 196(1):22-7. PMID: 26685315.
      View in: PubMed
    30. Jin N, Wang Y, Crawford F, White J, Marrack P, Dai S, Kappler JW. N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proc Natl Acad Sci U S A. 2015 Oct 27; 112(43):13318-23. PMID: 26453556.
      View in: PubMed
    31. Ning F, Wang C, Berry KZ, Kandasamy P, Liu H, Murphy RC, Voelker DR, Nho CW, Pan CH, Dai S, Niu L, Chu HW, Zhang G. Structural characterization of the pulmonary innate immune protein SPLUNC1 and identification of lipid ligands. FASEB J. 2014 Dec; 28(12):5349-60. PMID: 25223608.
      View in: PubMed
    32. Clayton GM, Wang Y, Crawford F, Novikov A, Wimberly BT, Kieft JS, Falta MT, Bowerman NA, Marrack P, Fontenot AP, Dai S, Kappler JW. Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell. 2014 Jul 03; 158(1):132-42. PMID: 24995984.
      View in: PubMed
    33. Dai S, Falta MT, Bowerman NA, McKee AS, Fontenot AP. T cell recognition of beryllium. Curr Opin Immunol. 2013 Dec; 25(6):775-80. PMID: 23978481.
      View in: PubMed
    34. Wang Y, Dai S. Structural basis of metal hypersensitivity. Immunol Res. 2013 Mar; 55(1-3):83-90. PMID: 22983897.
      View in: PubMed
    35. Yin L, Dai S, Clayton G, Gao W, Wang Y, Kappler J, Marrack P. Recognition of self and altered self by T cells in autoimmunity and allergy. Protein Cell. 2013 Jan; 4(1):8-16. PMID: 23307779.
      View in: PubMed
    36. Yin L, Crawford F, Marrack P, Kappler JW, Dai S. T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc Natl Acad Sci U S A. 2012 Nov 06; 109(45):18517-22. PMID: 23091041.
      View in: PubMed
    37. Dai SX, Zhang AD, Huang JF. Evolution, expansion and expression of the Kunitz/BPTI gene family associated with long-term blood feeding in Ixodes Scapularis. BMC Evol Biol. 2012 Jan 14; 12:4. PMID: 22244187.
      View in: PubMed
    38. Yin L, Huseby E, Scott-Browne J, Rubtsova K, Pinilla C, Crawford F, Marrack P, Dai S, Kappler JW. A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers. Immunity. 2011 Jul 22; 35(1):23-33. PMID: 21683626.
      View in: PubMed
    39. Hong X, Zang J, White J, Wang C, Pan CH, Zhao R, Murphy RC, Dai S, Henson P, Kappler JW, Hagman J, Zhang G. Interaction of JMJD6 with single-stranded RNA. Proc Natl Acad Sci U S A. 2010 Aug 17; 107(33):14568-72. PMID: 20679243.
      View in: PubMed
    40. Bui MR, Hodson V, King T, Leopold D, Dai S, Fiolkoski V, Oakes S, Duke R, Apelian D, Franzusoff A, DeGregori J. Mutation-specific control of BCR-ABL T315I positive leukemia with a recombinant yeast-based therapeutic vaccine in a murine model. Vaccine. 2010 Aug 23; 28(37):6028-35. PMID: 20619375.
      View in: PubMed
    41. Falta MT, Bowerman NA, Dai S, Kappler JW, Fontenot AP. Linking genetic susceptibility and T cell activation in beryllium-induced disease. Proc Am Thorac Soc. 2010 May; 7(2):126-9. PMID: 20427584.
      View in: PubMed
    42. Dai S, Murphy GA, Crawford F, Mack DG, Falta MT, Marrack P, Kappler JW, Fontenot AP. Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7425-30. PMID: 20356827.
      View in: PubMed
    43. Rubtsova K, Scott-Browne JP, Crawford F, Dai S, Marrack P, Kappler JW. Many different Vbeta CDR3s can reveal the inherent MHC reactivity of germline-encoded TCR V regions. Proc Natl Acad Sci U S A. 2009 May 12; 106(19):7951-6. PMID: 19416894.
      View in: PubMed
    44. Dai S, Crawford F, Marrack P, Kappler JW. The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles. Proc Natl Acad Sci U S A. 2008 Aug 19; 105(33):11893-7. PMID: 18697946.
      View in: PubMed
    45. Dai S, Huseby ES, Rubtsova K, Scott-Browne J, Crawford F, Macdonald WA, Marrack P, Kappler JW. Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules. Immunity. 2008 Mar; 28(3):324-34. PMID: 18308592.
      View in: PubMed
    46. Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu Rev Immunol. 2008; 26:171-203. PMID: 18304006.
      View in: PubMed
    47. Dai S, Friemann R, Glauser DA, Bourquin F, Manieri W, Sch?rmann P, Eklund H. Structural snapshots along the reaction pathway of ferredoxin-thioredoxin reductase. Nature. 2007 Jul 05; 448(7149):92-6. PMID: 17611542.
      View in: PubMed
    48. Chen Z, Zang J, Kappler J, Hong X, Crawford F, Wang Q, Lan F, Jiang C, Whetstine J, Dai S, Hansen K, Shi Y, Zhang G. Structural basis of the recognition of a methylated histone tail by JMJD2A. Proc Natl Acad Sci U S A. 2007 Jun 26; 104(26):10818-23. PMID: 17567753.
      View in: PubMed
    49. Liu X, Zhu Y, Dai S, White J, Peyerl F, Kappler JW, Marrack P. Bcl-xl does not have to bind Bax to protect T cells from death. J Exp Med. 2006 Dec 25; 203(13):2953-61. PMID: 17158961.
      View in: PubMed
    50. Horsman GP, Ke J, Dai S, Seah SY, Bolin JT, Eltis LD. Kinetic and structural insight into the mechanism of BphD, a C-C bond hydrolase from the biphenyl degradation pathway. Biochemistry. 2006 Sep 19; 45(37):11071-86. PMID: 16964968.
      View in: PubMed
    51. Chen Z, Zang J, Whetstine J, Hong X, Davrazou F, Kutateladze TG, Simpson M, Mao Q, Pan CH, Dai S, Hagman J, Hansen K, Shi Y, Zhang G. Structural insights into histone demethylation by JMJD2 family members. Cell. 2006 May 19; 125(4):691-702. PMID: 16677698.
      View in: PubMed
    52. Dai S, Johansson K, Miginiac-Maslow M, Sch?rmann P, Eklund H. Structural Basis of Redox Signaling in Photosynthesis: Structure and Function of Ferredoxin:thioredoxin Reductase and Target Enzymes. Photosynth Res. 2004; 79(3):233-48. PMID: 16328790.
      View in: PubMed
    53. Liu X, Dai S, Zhu Y, Marrack P, Kappler JW. The structure of a Bcl-xL/Bim fragment complex: implications for Bim function. Immunity. 2003 Sep; 19(3):341-52. PMID: 14499110.
      View in: PubMed
    54. Li R, Manna AC, Dai S, Cheung AL, Zhang G. Crystal structure of the SarS protein from Staphylococcus aureus. J Bacteriol. 2003 Jul; 185(14):4219-25. PMID: 12837797.
      View in: PubMed
    55. Liu Y, Hong X, Kappler J, Jiang L, Zhang R, Xu L, Pan CH, Martin WE, Murphy RC, Shu HB, Dai S, Zhang G. Ligand-receptor binding revealed by the TNF family member TALL-1. Nature. 2003 May 01; 423(6935):49-56. PMID: 12721620.
      View in: PubMed
    56. Dai S, Vaillancourt FH, Maaroufi H, Drouin NM, Neau DB, Snieckus V, Bolin JT, Eltis LD. Identification and analysis of a bottleneck in PCB biodegradation. Nat Struct Biol. 2002 Dec; 9(12):934-9. PMID: 12415290.
      View in: PubMed
    57. Liu X, Dai S, Crawford F, Fruge R, Marrack P, Kappler J. Alternate interactions define the binding of peptides to the MHC molecule IA(b). Proc Natl Acad Sci U S A. 2002 Jun 25; 99(13):8820-5. PMID: 12084926.
      View in: PubMed
    58. Fremont DH, Dai S, Chiang H, Crawford F, Marrack P, Kappler J. Structural basis of cytochrome c presentation by IE(k). J Exp Med. 2002 Apr 15; 195(8):1043-52. PMID: 11956295.
      View in: PubMed
    Dai's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (312) concept(s)
    _
    Co-Authors Expand Description
    See all (32) people
    _
    Similar People Expand Description
    See all (60) people
    _
    Same Department Expand Description
    Search Department

    Copyright © 2024 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)