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																		 Cell-Free System
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"Cell-Free System" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				A fractionated cell extract that maintains a biological function. A subcellular fraction isolated by ultracentrifugation or other separation techniques must first be isolated so that a process can be studied free from all of the complex side reactions that occur in a cell. The cell-free system is therefore widely used in cell biology. (From Alberts et al., Molecular Biology of the Cell, 2d ed, p166)
    
			 
				
				
					
						| Descriptor ID | D002474 |  
						| MeSH Number(s) | A11.284.835.168 |  
						| Concept/Terms | Cell-Free SystemCell-Free SystemCell Free SystemCell-Free SystemsSystem, Cell-FreeSystems, Cell-FreeCellfree SystemCellfree SystemsSystem, CellfreeSystems, Cellfree
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				Below are MeSH descriptors whose meaning is more general than "Cell-Free System". 
				Below are MeSH descriptors whose meaning is more specific than "Cell-Free System". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "Cell-Free System" by people in this website by year, and whether "Cell-Free System" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 1995 | 0 | 1 | 1 |  | 1996 | 0 | 1 | 1 |  | 1997 | 0 | 1 | 1 |  | 1999 | 0 | 2 | 2 |  | 2001 | 0 | 2 | 2 |  | 2003 | 0 | 2 | 2 |  | 2006 | 1 | 2 | 3 |  | 2007 | 0 | 1 | 1 |  | 2008 | 0 | 2 | 2 |  | 2009 | 0 | 1 | 1 |  | 2010 | 0 | 2 | 2 |  | 2011 | 0 | 4 | 4 |  | 2012 | 0 | 3 | 3 |  | 2014 | 2 | 2 | 4 |  | 2015 | 1 | 0 | 1 |  | 2016 | 0 | 1 | 1 |  | 2019 | 0 | 1 | 1 |  | 2021 | 0 | 1 | 1 | 
 
                    To return to the timeline, click here. 
				Below are the most recent publications written about "Cell-Free System" by people in Profiles. 		
					
								
								Keogh RA, Zapf RL, Frey A, Marino EC, Null GG, Wiemels RE, Holzschu DL, Shaw LN, Carroll RK. Staphylococcus aureus Trigger Factor Is Involved in Biofilm Formation and Cooperates with the Chaperone PpiB. J Bacteriol. 2021 03 08; 203(7).
								Kushnir VM, Mullady DK, Das K, Lang G, Hollander TG, Murad FM, Jackson SA, Toney NA, Finkelstein SD, Edmundowicz SA. The Diagnostic Yield of Malignancy Comparing Cytology, FISH, and Molecular Analysis of Cell Free Cytology Brush Supernatant in Patients With Biliary Strictures Undergoing Endoscopic Retrograde Cholangiography (ERC): A Prospective Study. J Clin Gastroenterol. 2019 10; 53(9):686-692.
								Gross L, Vicens Q, Einhorn E, Noireterre A, Schaeffer L, Kuhn L, Imler JL, Eriani G, Meignin C, Martin F. The IRES5'UTR of the dicistrovirus cricket paralysis virus is a type III IRES containing an essential pseudoknot structure. Nucleic Acids Res. 2017 Sep 06; 45(15):8993-9004.
								Movassat M, Shenasa H, Hertel KJ. Preparation of Splicing Competent Nuclear Extract from Mammalian Cells and In Vitro Pre-mRNA Splicing Assay. Methods Mol Biol. 2017; 1648:11-26.
								Currier NV, Ackerman SE, Kintzing JR, Chen R, Filsinger Interrante M, Steiner A, Sato AK, Cochran JR. Targeted Drug Delivery with an Integrin-Binding Knottin-Fc-MMAF Conjugate Produced by Cell-Free Protein Synthesis. Mol Cancer Ther. 2016 06; 15(6):1291-300.
								Aceti DJ, Bingman CA, Wrobel RL, Frederick RO, Makino S, Nichols KW, Sahu SC, Bergeman LF, Blommel PG, Cornilescu CC, Gromek KA, Seder KD, Hwang S, Primm JG, Sabat G, Vojtik FC, Volkman BF, Zolnai Z, Phillips GN, Markley JL, Fox BG. Expression platforms for producing eukaryotic proteins: a comparison of E. coli cell-based and wheat germ cell-free synthesis, affinity and solubility tags, and cloning strategies. J Struct Funct Genomics. 2015 Jun; 16(2):67-80.
								Boerneke MA, Dibrov SM, Gu J, Wyles DL, Hermann T. Functional conservation despite structural divergence in ligand-responsive RNA switches. Proc Natl Acad Sci U S A. 2014 Nov 11; 111(45):15952-7.
								Allyse M, Sayres LC, Goodspeed TA, Cho MK. Attitudes towards non-invasive prenatal testing for aneuploidy among US adults of reproductive age. J Perinatol. 2014 Jun; 34(6):429-34.
								Makino S, Beebe ET, Markley JL, Fox BG. Cell-free protein synthesis for functional and structural studies. Methods Mol Biol. 2014; 1091:161-78.
								Beebe ET, Makino S, Markley JL, Fox BG. Automated cell-free protein production methods for structural studies. Methods Mol Biol. 2014; 1140:117-35. | 
																	
																		
																			
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