Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joseph Falke

Concepts (378)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Chemotaxis
43
2018
129
6.800
Why?
Membrane Proteins
45
2018
1117
5.270
Why?
Bacterial Proteins
40
2015
833
4.360
Why?
Receptors, Amino Acid
23
2009
25
3.740
Why?
Signal Transduction
42
2024
4926
3.570
Why?
ras Proteins
5
2024
144
3.490
Why?
Protein Kinase C-alpha
11
2023
37
3.190
Why?
Protein Kinases
18
2014
318
2.970
Why?
Lipid Bilayers
15
2023
97
2.860
Why?
Cell Membrane
24
2021
732
2.760
Why?
Disulfides
21
2014
97
2.670
Why?
Calcium
26
2018
1212
2.550
Why?
Escherichia coli Proteins
23
2015
178
2.500
Why?
Phosphatidylinositol 3-Kinases
5
2022
360
2.190
Why?
Protein Structure, Tertiary
33
2015
841
1.900
Why?
Escherichia coli
33
2015
766
1.740
Why?
Salmonella typhimurium
20
2014
174
1.740
Why?
Phosphatidylinositol Phosphates
6
2017
39
1.700
Why?
Mutagenesis, Site-Directed
27
2014
361
1.670
Why?
Calcium-Binding Proteins
17
2003
211
1.670
Why?
Models, Molecular
43
2017
1486
1.640
Why?
Cysteine
20
2009
195
1.630
Why?
Aspartic Acid
16
2009
80
1.620
Why?
Protein Conformation
35
2016
861
1.600
Why?
Receptors, Cytoplasmic and Nuclear
8
2013
217
1.540
Why?
Phospholipases A
12
2007
99
1.480
Why?
Methyl-Accepting Chemotaxis Proteins
24
2015
25
1.390
Why?
Phosphatidylinositol 4,5-Diphosphate
7
2016
31
1.240
Why?
Histidine Kinase
19
2015
34
1.200
Why?
Protein Kinase C
6
2018
260
1.140
Why?
Protein Binding
26
2023
2120
1.140
Why?
Monosaccharide Transport Proteins
10
1997
49
1.130
Why?
Periplasmic Binding Proteins
9
1997
13
1.130
Why?
Guanosine Triphosphate
3
2022
92
1.090
Why?
Kinetics
34
2014
1644
1.080
Why?
Binding Sites
29
2013
1249
1.050
Why?
Protein Structure, Secondary
16
2013
340
1.040
Why?
Macrophages
5
2020
1484
0.950
Why?
Guanosine Diphosphate
2
2021
20
0.910
Why?
Electron Spin Resonance Spectroscopy
8
2012
91
0.890
Why?
Multiprotein Complexes
3
2014
155
0.890
Why?
Receptors, Cell Surface
13
2007
380
0.880
Why?
Calcium Signaling
5
2014
250
0.870
Why?
Myristoylated Alanine-Rich C Kinase Substrate
3
2018
6
0.860
Why?
Calmodulin
4
2016
76
0.860
Why?
Protein Interaction Mapping
4
2010
108
0.850
Why?
Intracellular Signaling Peptides and Proteins
2
2016
442
0.840
Why?
Phosphatidylinositols
3
2022
57
0.810
Why?
Chemoreceptor Cells
7
2007
53
0.790
Why?
Models, Chemical
10
2013
262
0.750
Why?
Guanine Nucleotides
1
2021
15
0.750
Why?
Recombinant Proteins
13
2021
1304
0.750
Why?
Cytosol
7
2007
219
0.720
Why?
Protein Engineering
19
2013
106
0.720
Why?
Class III Phosphatidylinositol 3-Kinases
1
2020
2
0.710
Why?
rab5 GTP-Binding Proteins
1
2020
6
0.710
Why?
Pseudopodia
1
2020
25
0.670
Why?
Phosphatidylserines
6
2014
88
0.660
Why?
Endosomes
1
2020
126
0.640
Why?
Spin Labels
5
2008
46
0.640
Why?
Chromatography, High Pressure Liquid
1
2021
580
0.630
Why?
Amino Acid Substitution
11
2014
282
0.590
Why?
Receptors, Platelet-Derived Growth Factor
1
2017
14
0.580
Why?
Proto-Oncogene Proteins c-akt
2
2011
431
0.570
Why?
Conserved Sequence
3
2007
227
0.560
Why?
Cytoplasm
6
2005
265
0.550
Why?
Enzyme Activation
9
2017
812
0.550
Why?
Phosphatidylinositol 3-Kinase
1
2016
26
0.530
Why?
Carrier Proteins
9
1997
742
0.530
Why?
Biochemistry
2
2007
38
0.520
Why?
Adaptor Proteins, Signal Transducing
3
2014
399
0.520
Why?
Dimerization
8
2013
191
0.510
Why?
Protein Interaction Domains and Motifs
3
2014
138
0.510
Why?
Fluorescence Resonance Energy Transfer
4
2013
175
0.510
Why?
Anion Exchange Protein 1, Erythrocyte
8
1986
22
0.500
Why?
Protein Stability
2
2014
162
0.500
Why?
Biophysics
4
2024
68
0.490
Why?
Mutation
11
2021
3710
0.490
Why?
Microscopy, Fluorescence
6
2017
398
0.470
Why?
Magnetic Resonance Spectroscopy
18
1996
537
0.460
Why?
Cystine
1
2014
17
0.460
Why?
Spectrometry, Fluorescence
9
2010
163
0.450
Why?
Eukaryotic Cells
1
2014
33
0.430
Why?
Cell Movement
3
2020
944
0.430
Why?
3-Phosphoinositide-Dependent Protein Kinases
1
2013
1
0.430
Why?
Chlorides
9
1986
139
0.430
Why?
Amino Acid Sequence
12
2016
2056
0.420
Why?
Galactose
8
1997
26
0.400
Why?
Lipid Metabolism
2
2007
497
0.400
Why?
Adaptation, Physiological
4
2020
513
0.390
Why?
Thermotoga maritima
2
2013
11
0.380
Why?
Endosomal Sorting Complexes Required for Transport
1
2012
35
0.380
Why?
Diffusion
3
2023
116
0.380
Why?
Membrane Lipids
2
2010
91
0.380
Why?
Point Mutation
3
2009
224
0.360
Why?
Vesicular Transport Proteins
1
2012
84
0.360
Why?
Amino Acid Motifs
2
2009
213
0.350
Why?
Phosphorylation
7
2021
1710
0.350
Why?
Models, Theoretical
3
2005
546
0.350
Why?
Protein Structure, Quaternary
2
2013
122
0.340
Why?
RAW 264.7 Cells
2
2020
49
0.320
Why?
Bacterial Physiological Phenomena
3
2007
57
0.310
Why?
Animals
19
2024
35307
0.300
Why?
Peptide Fragments
5
2016
692
0.300
Why?
Isoenzymes
3
2008
302
0.300
Why?
Bacteria
3
2014
812
0.300
Why?
Oncogenes
1
2008
112
0.290
Why?
Static Electricity
6
2013
116
0.290
Why?
Tryptophan
5
2014
178
0.280
Why?
Humans
36
2024
129248
0.270
Why?
Membrane Microdomains
2
2003
33
0.260
Why?
Glycine
2
2005
165
0.260
Why?
Protein Domains
2
2017
253
0.250
Why?
Cell Line
5
2018
2779
0.250
Why?
Edetic Acid
2
2003
46
0.230
Why?
Single Molecule Imaging
1
2024
35
0.220
Why?
Cell Polarity
2
2020
139
0.220
Why?
Hot Temperature
4
2021
369
0.210
Why?
Protein Kinase C beta
3
2014
21
0.210
Why?
Cations, Divalent
4
2010
54
0.210
Why?
Spin Trapping
1
2003
3
0.210
Why?
Water
3
2004
440
0.210
Why?
Recombinant Fusion Proteins
4
2010
648
0.200
Why?
Peptides
2
2000
923
0.200
Why?
Surface Properties
5
2004
397
0.200
Why?
Mice
8
2020
16915
0.200
Why?
Plasmids
5
2007
358
0.200
Why?
Electrophoresis, Polyacrylamide Gel
4
2009
327
0.200
Why?
Molecular Dynamics Simulation
4
2014
217
0.200
Why?
Phosphatidylcholines
5
2007
145
0.190
Why?
Cyclophilin A
1
2002
26
0.190
Why?
Phosphotransferases
1
2001
24
0.190
Why?
Receptors, G-Protein-Coupled
1
2004
207
0.190
Why?
Chemotactic Factors
2
2007
54
0.180
Why?
Fluorescent Dyes
4
2007
312
0.180
Why?
Hydrolysis
1
2021
186
0.180
Why?
Spectrophotometry, Ultraviolet
1
2021
84
0.180
Why?
Reproducibility of Results
3
2021
3079
0.180
Why?
Metals
3
1997
123
0.180
Why?
Aspartate Kinase
1
2000
1
0.180
Why?
Molecular Sequence Data
6
2005
2835
0.170
Why?
Intracellular Membranes
1
2020
83
0.170
Why?
Glutamic Acid
3
2011
235
0.170
Why?
Diclofenac
1
2020
15
0.170
Why?
Time-Lapse Imaging
1
2020
20
0.170
Why?
Chelating Agents
2
1997
68
0.170
Why?
Lymphocyte Antigen 96
2
2010
24
0.160
Why?
Ibuprofen
1
2020
81
0.160
Why?
Endocytosis
1
2020
163
0.160
Why?
Alanine
2
2013
142
0.160
Why?
Troponin C
1
1998
5
0.160
Why?
Ultraviolet Rays
1
2021
382
0.150
Why?
Oxidation-Reduction
3
2010
1028
0.150
Why?
Membranes, Artificial
1
1998
70
0.150
Why?
Thermodynamics
6
2002
406
0.150
Why?
Crystallography, X-Ray
3
2013
435
0.150
Why?
Phospholipases A2
5
2006
79
0.150
Why?
Phosphopeptides
1
2017
18
0.140
Why?
Synaptotagmins
2
2012
20
0.140
Why?
Acetaminophen
1
2020
246
0.140
Why?
Solvents
4
1999
108
0.140
Why?
Terbium
2
1996
4
0.140
Why?
Biophysical Phenomena
3
2010
64
0.140
Why?
Sf9 Cells
1
2016
9
0.140
Why?
Aspirin
1
2020
380
0.130
Why?
Spodoptera
1
2016
37
0.130
Why?
Magnesium
3
1998
153
0.130
Why?
Leukocytes
1
2018
306
0.130
Why?
Structure-Activity Relationship
6
2013
543
0.130
Why?
Ligands
5
2010
621
0.130
Why?
Fluorine Radioisotopes
1
1996
11
0.130
Why?
Cloning, Molecular
5
1997
525
0.130
Why?
Cattle
2
2008
977
0.120
Why?
Erythrocyte Membrane
8
1986
49
0.120
Why?
Group IV Phospholipases A2
3
2006
47
0.120
Why?
Fluorine
5
1993
15
0.120
Why?
Macromolecular Substances
3
2010
216
0.120
Why?
Osmolar Concentration
3
2009
166
0.120
Why?
Glutathione Transferase
2
2007
102
0.120
Why?
Substrate Specificity
3
2008
368
0.120
Why?
Protein Transport
2
2007
428
0.110
Why?
Hydrophobic and Hydrophilic Interactions
2
2012
184
0.110
Why?
Protein Isoforms
2
2013
389
0.110
Why?
Microarray Analysis
1
2014
117
0.110
Why?
Bacteriorhodopsins
2
2005
11
0.110
Why?
Phospholipids
2
2013
215
0.110
Why?
Hydrogen-Ion Concentration
4
2009
541
0.110
Why?
Immunity, Innate
1
2020
803
0.110
Why?
Neoplasms
1
2008
2449
0.110
Why?
Models, Biological
6
2007
1722
0.110
Why?
Protein Folding
3
2002
264
0.110
Why?
Biological Transport, Active
7
1986
78
0.110
Why?
Proteolysis
1
2014
167
0.110
Why?
Histidine
2
2007
60
0.110
Why?
Protein Denaturation
3
2002
74
0.110
Why?
Phospholipases A2, Cytosolic
1
2013
7
0.110
Why?
Nuclear Magnetic Resonance, Biomolecular
2
2007
257
0.110
Why?
Protein Multimerization
1
2014
178
0.100
Why?
Myocardium
1
1998
978
0.100
Why?
Fibroblasts
1
2018
947
0.100
Why?
Molecular Docking Simulation
1
2013
108
0.100
Why?
Mutagenesis
1
2013
181
0.100
Why?
Trypsin
1
2012
74
0.100
Why?
Synaptotagmin I
1
2012
13
0.100
Why?
Multienzyme Complexes
1
2012
68
0.100
Why?
Bacterial Outer Membrane Proteins
1
2012
58
0.100
Why?
Computer Simulation
5
2013
939
0.100
Why?
Molecular Structure
4
1996
478
0.100
Why?
Myosin-Light-Chain Kinase
1
2012
20
0.100
Why?
Transfection
2
2011
915
0.100
Why?
NIH 3T3 Cells
1
2011
140
0.090
Why?
Energy Transfer
2
2002
50
0.090
Why?
Time Factors
2
2016
6543
0.090
Why?
Fluoresceins
2
2003
47
0.090
Why?
Carbohydrate Metabolism
1
1991
62
0.090
Why?
In Vitro Techniques
3
2003
1085
0.090
Why?
Facilitated Diffusion
1
2010
3
0.090
Why?
Toll-Like Receptor 4
2
2010
263
0.090
Why?
Hydrodynamics
1
2010
40
0.090
Why?
Niflumic Acid
2
1986
3
0.080
Why?
Sequence Homology, Amino Acid
2
2004
372
0.080
Why?
Heterocyclic Compounds, 3-Ring
1
2010
31
0.080
Why?
Toll-Like Receptors
1
2010
179
0.080
Why?
Crystallization
2
2013
138
0.080
Why?
Single-Cell Analysis
1
2011
275
0.080
Why?
Methyltransferases
1
2009
70
0.080
Why?
Photobleaching
1
2009
23
0.080
Why?
Least-Squares Analysis
1
2009
78
0.080
Why?
3T3 Cells
1
2008
153
0.080
Why?
Cations
2
2002
79
0.080
Why?
Hydrogen Bonding
2
2014
149
0.070
Why?
Blood Proteins
2
2013
244
0.070
Why?
Ethylmaleimide
2
2003
18
0.070
Why?
Receptors, Neurotransmitter
1
1987
17
0.070
Why?
Phosphoproteins
2
2013
332
0.070
Why?
Sensory Receptor Cells
1
1988
103
0.070
Why?
Archaeal Proteins
1
2007
49
0.070
Why?
Cell Survival
2
2008
1074
0.070
Why?
Nicotinic Acids
1
1986
6
0.070
Why?
Oligonucleotide Probes
1
2007
50
0.070
Why?
Benzenesulfonates
1
1986
19
0.070
Why?
Feedback
1
2007
162
0.070
Why?
Oxadiazoles
1
1986
33
0.070
Why?
Taurine
1
1986
43
0.070
Why?
Lysine
1
2008
286
0.060
Why?
Methylation
2
1997
230
0.060
Why?
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
1
1985
12
0.060
Why?
Structural Homology, Protein
1
2005
25
0.060
Why?
Calcium Channel Blockers
1
1986
161
0.060
Why?
Swine
1
2008
760
0.060
Why?
Drug Delivery Systems
1
2008
333
0.060
Why?
Actins
1
2007
411
0.060
Why?
Organometallic Compounds
2
2000
106
0.060
Why?
Motion
2
1996
98
0.060
Why?
Sequence Homology
1
2004
40
0.060
Why?
Phosphatidylethanolamines
2
2002
74
0.060
Why?
Analgesics, Opioid
2
2010
909
0.060
Why?
Mathematics
4
1985
102
0.060
Why?
Dogs
1
2005
382
0.060
Why?
Halobacterium
1
1984
3
0.060
Why?
Periplasm
1
2004
11
0.060
Why?
Membrane Potentials
1
2005
293
0.060
Why?
Rhodopsin
1
2004
11
0.060
Why?
Carotenoids
1
1984
41
0.050
Why?
Liposomes
2
2012
171
0.050
Why?
Lipopolysaccharides
1
2007
877
0.050
Why?
Computer Graphics
2
1996
41
0.050
Why?
Rhodamines
1
2003
18
0.050
Why?
Cyclic N-Oxides
1
2003
29
0.050
Why?
Data Interpretation, Statistical
1
2004
336
0.050
Why?
Fluorescein
1
2003
24
0.050
Why?
Peptide Library
1
2003
84
0.050
Why?
Urea
1
2002
76
0.050
Why?
Glucose
3
1992
1001
0.050
Why?
Peptide Hydrolases
1
2003
107
0.050
Why?
Dansyl Compounds
1
2002
5
0.050
Why?
Sulfhydryl Compounds
2
1998
187
0.050
Why?
Catalysis
1
2002
307
0.040
Why?
Lipids
1
2005
625
0.040
Why?
Proteins
1
2007
941
0.040
Why?
Nitrogen
1
2002
162
0.040
Why?
Chlorine
3
1985
58
0.040
Why?
Stilbenes
3
1985
36
0.040
Why?
Arginine
1
2002
265
0.040
Why?
Nitrilotriacetic Acid
1
2000
1
0.040
Why?
Benzoxazoles
1
1980
20
0.040
Why?
Chromatography, Affinity
1
2000
83
0.040
Why?
Indicators and Reagents
1
2000
109
0.040
Why?
Nickel
1
2000
54
0.040
Why?
Sequence Alignment
2
1998
332
0.040
Why?
Staining and Labeling
1
1980
141
0.040
Why?
Iodides
1
1998
6
0.040
Why?
Pyrimidinones
1
1980
103
0.040
Why?
Naphthalenesulfonates
1
1998
7
0.040
Why?
Fluorescence Polarization
1
1998
38
0.040
Why?
Isotopes
2
1991
32
0.040
Why?
Muscles
1
1980
321
0.040
Why?
Membrane Glycoproteins
1
2001
476
0.040
Why?
Chickens
1
1998
189
0.040
Why?
Pain Measurement
2
2010
506
0.030
Why?
Nerve Tissue Proteins
1
2001
569
0.030
Why?
Sequence Analysis
1
1996
37
0.030
Why?
Solubility
1
1997
232
0.030
Why?
Strontium
2
1998
14
0.030
Why?
Chemistry, Physical
1
1996
37
0.030
Why?
Chemical Phenomena
1
1996
82
0.030
Why?
Models, Structural
1
1995
39
0.030
Why?
Tetrahydrofolate Dehydrogenase
1
1996
23
0.030
Why?
L-Lactate Dehydrogenase
1
1996
119
0.030
Why?
Genetic Engineering
1
1996
86
0.030
Why?
Flagella
1
1995
19
0.030
Why?
Anions
2
1985
31
0.030
Why?
Genes, Bacterial
1
1995
157
0.030
Why?
p-Fluorophenylalanine
1
1994
2
0.030
Why?
Glutamates
1
1994
57
0.030
Why?
Electrons
1
2014
77
0.030
Why?
Cations, Monovalent
1
1993
6
0.030
Why?
Carboxylic Acids
1
1993
32
0.030
Why?
Movement
1
1995
269
0.030
Why?
Cryoelectron Microscopy
1
2014
177
0.030
Why?
Iodoacetamide
1
1992
5
0.030
Why?
Trehalose
1
2012
30
0.020
Why?
Organophosphates
1
1993
120
0.020
Why?
Rats
2
2010
5482
0.020
Why?
Gadolinium
1
1991
78
0.020
Why?
Molecular Conformation
1
1991
141
0.020
Why?
Lac Operon
1
1990
45
0.020
Why?
Infusion Pumps
1
2009
31
0.020
Why?
Toll-Like Receptor 2
1
2010
113
0.020
Why?
Myeloid Differentiation Factor 88
1
2010
96
0.020
Why?
Injections, Spinal
1
2009
104
0.020
Why?
Receptors, Opioid, mu
1
2009
65
0.020
Why?
Morphine
1
2010
137
0.020
Why?
Gene Expression Regulation, Bacterial
1
1991
323
0.020
Why?
Hyperalgesia
1
2009
123
0.020
Why?
Naloxone
1
2009
112
0.020
Why?
Analgesia
1
2009
100
0.020
Why?
Microglia
1
2010
232
0.020
Why?
Reaction Time
1
2009
410
0.020
Why?
Narcotic Antagonists
1
2009
164
0.020
Why?
Allosteric Regulation
1
1987
99
0.020
Why?
Species Specificity
1
1988
574
0.020
Why?
Substance Withdrawal Syndrome
1
2009
176
0.020
Why?
Mice, Inbred BALB C
1
2010
1247
0.020
Why?
Dinitrofluorobenzene
1
1986
6
0.020
Why?
Cyclohexanones
1
1986
9
0.020
Why?
Dipyridamole
1
1986
28
0.020
Why?
Cell Fractionation
1
1986
56
0.020
Why?
Phenylglyoxal
1
1985
1
0.020
Why?
Papain
1
1985
5
0.020
Why?
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid
1
1985
8
0.020
Why?
Interleukin-1
1
2010
959
0.020
Why?
Chymotrypsin
1
1985
19
0.020
Why?
Bromine
1
1985
5
0.020
Why?
Sonication
1
1985
13
0.020
Why?
Bicarbonates
1
1985
42
0.020
Why?
Promoter Regions, Genetic
1
1990
1204
0.020
Why?
Tumor Necrosis Factor-alpha
1
2010
1202
0.010
Why?
Muscle, Skeletal
1
1994
1613
0.010
Why?
Biological Transport
1
1985
403
0.010
Why?
Cytoskeleton
1
1985
183
0.010
Why?
Halorhodopsins
1
1984
1
0.010
Why?
Bromides
1
1984
5
0.010
Why?
Cold Temperature
1
1985
154
0.010
Why?
Radioisotopes
1
1984
31
0.010
Why?
Binding, Competitive
1
1984
206
0.010
Why?
Rats, Sprague-Dawley
1
2009
2396
0.010
Why?
Mice, Knockout
1
2010
2871
0.010
Why?
Cells, Cultured
1
2010
4076
0.010
Why?
Chick Embryo
1
1980
130
0.010
Why?
Cell Membrane Permeability
1
1980
82
0.010
Why?
Barium
1
1998
28
0.010
Why?
CHO Cells
1
1998
154
0.010
Why?
COS Cells
1
1998
186
0.010
Why?
Cricetinae
1
1998
278
0.010
Why?
Blood Glucose
1
1986
2097
0.010
Why?
Male
2
2010
63501
0.010
Why?
Cytochalasin B
1
1986
17
0.000
Why?
Falke's Networks
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