Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joseph Falke

Concepts (376)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Chemotaxis
43
2018
132
7.130
Why?
Membrane Proteins
45
2018
1024
5.660
Why?
Bacterial Proteins
40
2015
739
4.730
Why?
Receptors, Amino Acid
23
2009
25
3.930
Why?
Signal Transduction
41
2023
4541
3.520
Why?
Protein Kinase C-alpha
11
2023
41
3.340
Why?
Protein Kinases
18
2014
306
3.130
Why?
Lipid Bilayers
15
2023
101
2.980
Why?
Cell Membrane
24
2021
683
2.900
Why?
Disulfides
21
2014
91
2.810
Why?
ras Proteins
4
2022
138
2.800
Why?
Escherichia coli Proteins
23
2015
164
2.650
Why?
Calcium
25
2018
1103
2.630
Why?
Phosphatidylinositol 3-Kinases
5
2022
332
2.320
Why?
Protein Structure, Tertiary
32
2015
804
1.960
Why?
Escherichia coli
33
2015
730
1.860
Why?
Salmonella typhimurium
20
2014
161
1.820
Why?
Phosphatidylinositol Phosphates
6
2017
38
1.790
Why?
Mutagenesis, Site-Directed
27
2014
346
1.760
Why?
Cysteine
20
2009
173
1.740
Why?
Models, Molecular
43
2017
1390
1.740
Why?
Aspartic Acid
16
2009
79
1.700
Why?
Protein Conformation
35
2016
822
1.680
Why?
Receptors, Cytoplasmic and Nuclear
8
2013
195
1.640
Why?
Calcium-Binding Proteins
16
2003
203
1.560
Why?
Phospholipases A
11
2007
101
1.500
Why?
Methyl-Accepting Chemotaxis Proteins
24
2015
25
1.460
Why?
Phosphatidylinositol 4,5-Diphosphate
7
2016
24
1.320
Why?
Histidine Kinase
19
2015
33
1.260
Why?
Protein Binding
26
2023
1917
1.260
Why?
Monosaccharide Transport Proteins
10
1997
45
1.190
Why?
Protein Kinase C
6
2018
274
1.190
Why?
Periplasmic Binding Proteins
9
1997
14
1.190
Why?
Kinetics
34
2014
1569
1.150
Why?
Guanosine Triphosphate
3
2022
85
1.150
Why?
Protein Structure, Secondary
16
2013
327
1.090
Why?
Binding Sites
28
2013
1177
1.070
Why?
Macrophages
5
2020
1284
1.050
Why?
Guanosine Diphosphate
2
2021
19
0.950
Why?
Multiprotein Complexes
3
2014
145
0.940
Why?
Electron Spin Resonance Spectroscopy
8
2012
87
0.940
Why?
Receptors, Cell Surface
13
2007
356
0.930
Why?
Intracellular Signaling Peptides and Proteins
2
2016
388
0.910
Why?
Calmodulin
4
2016
72
0.910
Why?
Myristoylated Alanine-Rich C Kinase Substrate
3
2018
5
0.910
Why?
Protein Interaction Mapping
4
2010
102
0.890
Why?
Calcium Signaling
4
2014
211
0.890
Why?
Phosphatidylinositols
3
2022
53
0.850
Why?
Chemoreceptor Cells
7
2007
54
0.840
Why?
Guanine Nucleotides
1
2021
16
0.790
Why?
Recombinant Proteins
13
2021
1243
0.790
Why?
Models, Chemical
10
2013
257
0.790
Why?
Cytosol
7
2007
209
0.760
Why?
Protein Engineering
19
2013
104
0.750
Why?
Class III Phosphatidylinositol 3-Kinases
1
2020
1
0.750
Why?
rab5 GTP-Binding Proteins
1
2020
6
0.750
Why?
Pseudopodia
1
2020
20
0.710
Why?
Phosphatidylserines
6
2014
87
0.700
Why?
Chromatography, High Pressure Liquid
1
2021
477
0.680
Why?
Endosomes
1
2020
125
0.680
Why?
Spin Labels
5
2008
48
0.670
Why?
Amino Acid Substitution
11
2014
267
0.620
Why?
Proto-Oncogene Proteins c-akt
2
2011
400
0.610
Why?
Receptors, Platelet-Derived Growth Factor
1
2017
13
0.610
Why?
Conserved Sequence
3
2007
219
0.590
Why?
Cytoplasm
6
2005
255
0.580
Why?
Enzyme Activation
9
2017
793
0.580
Why?
Phosphatidylinositol 3-Kinase
1
2016
26
0.560
Why?
Carrier Proteins
9
1997
701
0.560
Why?
Biochemistry
2
2007
40
0.550
Why?
Adaptor Proteins, Signal Transducing
3
2014
374
0.550
Why?
Dimerization
8
2013
177
0.540
Why?
Fluorescence Resonance Energy Transfer
4
2013
176
0.530
Why?
Protein Interaction Domains and Motifs
3
2014
135
0.530
Why?
Mutation
11
2021
3364
0.530
Why?
Anion Exchange Protein 1, Erythrocyte
8
1986
22
0.520
Why?
Protein Stability
2
2014
162
0.520
Why?
Magnetic Resonance Spectroscopy
18
1996
482
0.490
Why?
Microscopy, Fluorescence
6
2017
402
0.490
Why?
Cystine
1
2014
14
0.490
Why?
Cell Movement
3
2020
867
0.470
Why?
Eukaryotic Cells
1
2014
33
0.460
Why?
Chlorides
9
1986
130
0.450
Why?
3-Phosphoinositide-Dependent Protein Kinases
1
2013
1
0.450
Why?
Amino Acid Sequence
12
2016
2000
0.450
Why?
Spectrometry, Fluorescence
8
2010
158
0.430
Why?
Lipid Metabolism
2
2007
449
0.430
Why?
Galactose
8
1997
20
0.430
Why?
Adaptation, Physiological
4
2020
476
0.410
Why?
Thermotoga maritima
2
2013
10
0.400
Why?
Endosomal Sorting Complexes Required for Transport
1
2012
36
0.400
Why?
Diffusion
3
2023
120
0.400
Why?
Membrane Lipids
2
2010
87
0.400
Why?
Point Mutation
3
2009
217
0.380
Why?
Vesicular Transport Proteins
1
2012
83
0.380
Why?
Phosphorylation
7
2021
1571
0.380
Why?
Amino Acid Motifs
2
2009
198
0.370
Why?
Models, Theoretical
3
2005
519
0.360
Why?
Protein Structure, Quaternary
2
2013
115
0.350
Why?
RAW 264.7 Cells
2
2020
41
0.330
Why?
Bacterial Physiological Phenomena
3
2007
57
0.330
Why?
Bacteria
3
2014
729
0.320
Why?
Peptide Fragments
5
2016
675
0.320
Why?
Isoenzymes
3
2008
285
0.310
Why?
Oncogenes
1
2008
104
0.310
Why?
Tryptophan
5
2014
136
0.300
Why?
Static Electricity
6
2013
117
0.300
Why?
Biophysics
3
2005
70
0.290
Why?
Humans
35
2021
115587
0.280
Why?
Membrane Microdomains
2
2003
32
0.270
Why?
Glycine
2
2005
156
0.270
Why?
Animals
17
2020
32102
0.270
Why?
Protein Domains
2
2017
209
0.270
Why?
Cell Line
5
2018
2651
0.260
Why?
Edetic Acid
2
2003
44
0.240
Why?
Cell Polarity
2
2020
131
0.240
Why?
Hot Temperature
4
2021
303
0.240
Why?
Mice
8
2020
15052
0.230
Why?
Protein Kinase C beta
3
2014
24
0.220
Why?
Water
3
2004
412
0.220
Why?
Cations, Divalent
4
2010
50
0.220
Why?
Spin Trapping
1
2003
3
0.220
Why?
Peptides
2
2000
864
0.220
Why?
Recombinant Fusion Proteins
4
2010
616
0.220
Why?
Surface Properties
5
2004
397
0.210
Why?
Plasmids
5
2007
345
0.210
Why?
Molecular Dynamics Simulation
4
2014
209
0.210
Why?
Electrophoresis, Polyacrylamide Gel
4
2009
312
0.210
Why?
Phosphatidylcholines
5
2007
134
0.210
Why?
Cyclophilin A
1
2002
24
0.200
Why?
Receptors, G-Protein-Coupled
1
2004
192
0.200
Why?
Phosphotransferases
1
2001
25
0.200
Why?
Chemotactic Factors
2
2007
47
0.190
Why?
Reproducibility of Results
3
2021
2800
0.190
Why?
Hydrolysis
1
2021
179
0.190
Why?
Spectrophotometry, Ultraviolet
1
2021
75
0.190
Why?
Metals
3
1997
109
0.190
Why?
Aspartate Kinase
1
2000
1
0.180
Why?
Glutamic Acid
3
2011
213
0.180
Why?
Intracellular Membranes
1
2020
73
0.180
Why?
Molecular Sequence Data
6
2005
2790
0.180
Why?
Diclofenac
1
2020
14
0.180
Why?
Time-Lapse Imaging
1
2020
19
0.180
Why?
Chelating Agents
2
1997
71
0.170
Why?
Lymphocyte Antigen 96
2
2010
24
0.170
Why?
Ibuprofen
1
2020
73
0.170
Why?
Endocytosis
1
2020
152
0.170
Why?
Alanine
2
2013
103
0.170
Why?
Oxidation-Reduction
3
2010
924
0.170
Why?
Troponin C
1
1998
5
0.160
Why?
Ultraviolet Rays
1
2021
372
0.160
Why?
Membranes, Artificial
1
1998
67
0.160
Why?
Crystallography, X-Ray
3
2013
408
0.160
Why?
Thermodynamics
6
2002
388
0.160
Why?
Phospholipases A2
5
2006
76
0.150
Why?
Phosphopeptides
1
2017
15
0.150
Why?
Synaptotagmins
2
2012
20
0.150
Why?
Aspirin
1
2020
326
0.150
Why?
Solvents
4
1999
108
0.150
Why?
Terbium
2
1996
4
0.150
Why?
Acetaminophen
1
2020
237
0.150
Why?
Fluorescent Dyes
3
2007
304
0.140
Why?
Sf9 Cells
1
2016
9
0.140
Why?
Biophysical Phenomena
3
2010
63
0.140
Why?
Spodoptera
1
2016
37
0.140
Why?
Magnesium
3
1998
145
0.140
Why?
Leukocytes
1
2018
281
0.140
Why?
Ligands
5
2010
569
0.140
Why?
Structure-Activity Relationship
6
2013
511
0.140
Why?
Fluorine Radioisotopes
1
1996
11
0.130
Why?
Cloning, Molecular
5
1997
523
0.130
Why?
Cattle
2
2008
935
0.130
Why?
Erythrocyte Membrane
8
1986
50
0.130
Why?
Group IV Phospholipases A2
3
2006
45
0.130
Why?
Fluorine
5
1993
15
0.130
Why?
Macromolecular Substances
3
2010
200
0.130
Why?
Osmolar Concentration
3
2009
178
0.130
Why?
Protein Isoforms
2
2013
339
0.120
Why?
Neoplasms
1
2008
2118
0.120
Why?
Glutathione Transferase
2
2007
95
0.120
Why?
Protein Transport
2
2007
400
0.120
Why?
Substrate Specificity
3
2008
357
0.120
Why?
Hydrophobic and Hydrophilic Interactions
2
2012
177
0.120
Why?
Immunity, Innate
1
2020
731
0.120
Why?
Microarray Analysis
1
2014
119
0.120
Why?
Bacteriorhodopsins
2
2005
10
0.120
Why?
Hydrogen-Ion Concentration
4
2009
515
0.120
Why?
Phospholipids
2
2013
202
0.120
Why?
Models, Biological
6
2007
1646
0.120
Why?
Protein Folding
3
2002
243
0.120
Why?
Biological Transport, Active
7
1986
71
0.120
Why?
Proteolysis
1
2014
145
0.110
Why?
Histidine
2
2007
57
0.110
Why?
Protein Denaturation
3
2002
72
0.110
Why?
Phospholipases A2, Cytosolic
1
2013
6
0.110
Why?
Fibroblasts
1
2018
839
0.110
Why?
Nuclear Magnetic Resonance, Biomolecular
2
2007
238
0.110
Why?
Protein Multimerization
1
2014
160
0.110
Why?
Myocardium
1
1998
926
0.110
Why?
Mutagenesis
1
2013
170
0.110
Why?
Molecular Docking Simulation
1
2013
102
0.110
Why?
Trypsin
1
2012
67
0.110
Why?
Synaptotagmin I
1
2012
13
0.110
Why?
Multienzyme Complexes
1
2012
64
0.110
Why?
Computer Simulation
5
2013
881
0.100
Why?
Bacterial Outer Membrane Proteins
1
2012
58
0.100
Why?
Molecular Structure
4
1996
447
0.100
Why?
Myosin-Light-Chain Kinase
1
2012
19
0.100
Why?
Transfection
2
2011
866
0.100
Why?
Time Factors
2
2016
6165
0.100
Why?
NIH 3T3 Cells
1
2011
137
0.100
Why?
Fluoresceins
2
2003
46
0.100
Why?
Carbohydrate Metabolism
1
1991
50
0.090
Why?
Facilitated Diffusion
1
2010
3
0.090
Why?
Hydrodynamics
1
2010
34
0.090
Why?
Niflumic Acid
2
1986
3
0.090
Why?
Toll-Like Receptor 4
2
2010
285
0.090
Why?
Sequence Homology, Amino Acid
2
2004
352
0.090
Why?
Heterocyclic Compounds, 3-Ring
1
2010
29
0.090
Why?
Single-Cell Analysis
1
2011
187
0.090
Why?
Toll-Like Receptors
1
2010
166
0.080
Why?
Methyltransferases
1
2009
61
0.080
Why?
Crystallization
2
2013
138
0.080
Why?
Photobleaching
1
2009
21
0.080
Why?
Least-Squares Analysis
1
2009
73
0.080
Why?
3T3 Cells
1
2008
137
0.080
Why?
Cations
2
2002
79
0.080
Why?
Hydrogen Bonding
2
2014
145
0.080
Why?
Blood Proteins
2
2013
238
0.080
Why?
Phosphoproteins
2
2013
304
0.080
Why?
Sensory Receptor Cells
1
1988
78
0.080
Why?
Ethylmaleimide
2
2003
18
0.080
Why?
Receptors, Neurotransmitter
1
1987
15
0.070
Why?
Archaeal Proteins
1
2007
45
0.070
Why?
Cell Survival
2
2008
1024
0.070
Why?
Nicotinic Acids
1
1986
6
0.070
Why?
Oligonucleotide Probes
1
2007
54
0.070
Why?
Benzenesulfonates
1
1986
21
0.070
Why?
Feedback
1
2007
148
0.070
Why?
Oxadiazoles
1
1986
32
0.070
Why?
Lysine
1
2008
245
0.070
Why?
Taurine
1
1986
41
0.070
Why?
Calcium Channel Blockers
1
1986
115
0.070
Why?
Methylation
2
1997
206
0.070
Why?
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
1
1985
12
0.070
Why?
Structural Homology, Protein
1
2005
23
0.070
Why?
Swine
1
2008
704
0.070
Why?
Drug Delivery Systems
1
2008
301
0.060
Why?
Analgesics, Opioid
2
2010
783
0.060
Why?
Actins
1
2007
383
0.060
Why?
Organometallic Compounds
2
2000
102
0.060
Why?
Motion
2
1996
94
0.060
Why?
Sequence Homology
1
2004
40
0.060
Why?
Mathematics
4
1985
100
0.060
Why?
Dogs
1
2005
341
0.060
Why?
Membrane Potentials
1
2005
251
0.060
Why?
Halobacterium
1
1984
3
0.060
Why?
Periplasm
1
2004
10
0.060
Why?
Rhodopsin
1
2004
9
0.060
Why?
Liposomes
2
2012
149
0.060
Why?
Lipopolysaccharides
1
2007
826
0.060
Why?
Carotenoids
1
1984
35
0.060
Why?
Computer Graphics
2
1996
43
0.060
Why?
Rhodamines
1
2003
17
0.050
Why?
Cyclic N-Oxides
1
2003
30
0.050
Why?
Fluorescein
1
2003
27
0.050
Why?
Data Interpretation, Statistical
1
2004
324
0.050
Why?
Peptide Library
1
2003
81
0.050
Why?
Glucose
3
1992
904
0.050
Why?
Urea
1
2002
69
0.050
Why?
Sulfhydryl Compounds
2
1998
178
0.050
Why?
Peptide Hydrolases
1
2003
109
0.050
Why?
In Vitro Techniques
2
2003
1044
0.050
Why?
Lipids
1
2005
588
0.050
Why?
Catalysis
1
2002
299
0.050
Why?
Nitrogen
1
2002
148
0.050
Why?
Energy Transfer
1
2001
47
0.050
Why?
Proteins
1
2007
920
0.050
Why?
Arginine
1
2002
241
0.050
Why?
Stilbenes
3
1985
36
0.050
Why?
Chlorine
3
1985
62
0.050
Why?
Nitrilotriacetic Acid
1
2000
1
0.040
Why?
Benzoxazoles
1
1980
16
0.040
Why?
Chromatography, Affinity
1
2000
83
0.040
Why?
Indicators and Reagents
1
2000
100
0.040
Why?
Nickel
1
2000
52
0.040
Why?
Sequence Alignment
2
1998
327
0.040
Why?
Staining and Labeling
1
1980
139
0.040
Why?
Pyrimidinones
1
1980
88
0.040
Why?
Iodides
1
1998
6
0.040
Why?
Fluorescence Polarization
1
1998
35
0.040
Why?
Naphthalenesulfonates
1
1998
7
0.040
Why?
Isotopes
2
1991
26
0.040
Why?
Membrane Glycoproteins
1
2001
431
0.040
Why?
Muscles
1
1980
326
0.040
Why?
Chickens
1
1998
183
0.040
Why?
Pain Measurement
2
2010
449
0.040
Why?
Nerve Tissue Proteins
1
2001
535
0.040
Why?
Sequence Analysis
1
1996
35
0.040
Why?
Solubility
1
1997
226
0.030
Why?
Strontium
2
1998
14
0.030
Why?
Tetrahydrofolate Dehydrogenase
1
1996
14
0.030
Why?
Chemistry, Physical
1
1996
38
0.030
Why?
Chemical Phenomena
1
1996
81
0.030
Why?
Models, Structural
1
1995
37
0.030
Why?
L-Lactate Dehydrogenase
1
1996
107
0.030
Why?
Genetic Engineering
1
1996
81
0.030
Why?
Flagella
1
1995
18
0.030
Why?
Anions
2
1985
31
0.030
Why?
Genes, Bacterial
1
1995
156
0.030
Why?
p-Fluorophenylalanine
1
1994
2
0.030
Why?
Glutamates
1
1994
59
0.030
Why?
Electrons
1
2014
72
0.030
Why?
Cations, Monovalent
1
1993
5
0.030
Why?
Cryoelectron Microscopy
1
2014
144
0.030
Why?
Carboxylic Acids
1
1993
26
0.030
Why?
Movement
1
1995
246
0.030
Why?
Iodoacetamide
1
1992
5
0.030
Why?
Trehalose
1
2012
29
0.030
Why?
Organophosphates
1
1993
90
0.030
Why?
Rats
2
2010
5034
0.020
Why?
Molecular Conformation
1
1991
139
0.020
Why?
Gadolinium
1
1991
78
0.020
Why?
Lac Operon
1
1990
46
0.020
Why?
Infusion Pumps
1
2009
32
0.020
Why?
Myeloid Differentiation Factor 88
1
2010
90
0.020
Why?
Toll-Like Receptor 2
1
2010
112
0.020
Why?
Injections, Spinal
1
2009
102
0.020
Why?
Receptors, Opioid, mu
1
2009
52
0.020
Why?
Morphine
1
2010
124
0.020
Why?
Gene Expression Regulation, Bacterial
1
1991
284
0.020
Why?
Naloxone
1
2009
99
0.020
Why?
Hyperalgesia
1
2009
107
0.020
Why?
Analgesia
1
2009
82
0.020
Why?
Microglia
1
2010
203
0.020
Why?
Reaction Time
1
2009
373
0.020
Why?
Narcotic Antagonists
1
2009
139
0.020
Why?
Allosteric Regulation
1
1987
84
0.020
Why?
Mice, Inbred BALB C
1
2010
1168
0.020
Why?
Species Specificity
1
1988
552
0.020
Why?
Dinitrofluorobenzene
1
1986
7
0.020
Why?
Substance Withdrawal Syndrome
1
2009
160
0.020
Why?
Cyclohexanones
1
1986
8
0.020
Why?
Dipyridamole
1
1986
26
0.020
Why?
Cell Fractionation
1
1986
53
0.020
Why?
Phenylglyoxal
1
1985
1
0.020
Why?
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid
1
1985
8
0.020
Why?
Papain
1
1985
4
0.020
Why?
Bromine
1
1985
5
0.020
Why?
Sonication
1
1985
10
0.020
Why?
Chymotrypsin
1
1985
20
0.020
Why?
Promoter Regions, Genetic
1
1990
1122
0.020
Why?
Bicarbonates
1
1985
42
0.020
Why?
Interleukin-1
1
2010
971
0.020
Why?
Muscle, Skeletal
1
1994
1447
0.020
Why?
Tumor Necrosis Factor-alpha
1
2010
1137
0.020
Why?
Cold Temperature
1
1985
128
0.020
Why?
Biological Transport
1
1985
375
0.010
Why?
Cytoskeleton
1
1985
177
0.010
Why?
Halorhodopsins
1
1984
1
0.010
Why?
Bromides
1
1984
5
0.010
Why?
Rats, Sprague-Dawley
1
2009
2262
0.010
Why?
Radioisotopes
1
1984
34
0.010
Why?
Binding, Competitive
1
1984
200
0.010
Why?
Mice, Knockout
1
2010
2604
0.010
Why?
Cells, Cultured
1
2010
3914
0.010
Why?
Phosphatidylethanolamines
1
2002
66
0.010
Why?
Chick Embryo
1
1980
122
0.010
Why?
Cell Membrane Permeability
1
1980
83
0.010
Why?
Barium
1
1998
25
0.010
Why?
CHO Cells
1
1998
140
0.010
Why?
COS Cells
1
1998
175
0.010
Why?
Cricetinae
1
1998
260
0.010
Why?
Blood Glucose
1
1986
1824
0.010
Why?
Male
2
2010
55949
0.010
Why?
Cytochalasin B
1
1986
17
0.000
Why?
Falke's Networks
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