Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joseph Falke

Concepts (378)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Chemotaxis
43
2018
129
6.830
Why?
Membrane Proteins
45
2018
1119
5.280
Why?
Bacterial Proteins
40
2015
835
4.370
Why?
Receptors, Amino Acid
23
2009
25
3.750
Why?
Signal Transduction
42
2024
4925
3.580
Why?
ras Proteins
5
2024
144
3.500
Why?
Protein Kinase C-alpha
11
2023
37
3.200
Why?
Protein Kinases
18
2014
318
2.980
Why?
Lipid Bilayers
15
2023
98
2.870
Why?
Cell Membrane
24
2021
732
2.770
Why?
Disulfides
21
2014
97
2.680
Why?
Calcium
26
2018
1213
2.560
Why?
Escherichia coli Proteins
23
2015
178
2.510
Why?
Phosphatidylinositol 3-Kinases
5
2022
359
2.200
Why?
Protein Structure, Tertiary
33
2015
840
1.910
Why?
Salmonella typhimurium
20
2014
175
1.740
Why?
Escherichia coli
33
2015
774
1.740
Why?
Phosphatidylinositol Phosphates
6
2017
39
1.710
Why?
Mutagenesis, Site-Directed
27
2014
361
1.680
Why?
Calcium-Binding Proteins
17
2003
210
1.670
Why?
Models, Molecular
43
2017
1492
1.640
Why?
Cysteine
20
2009
195
1.640
Why?
Aspartic Acid
16
2009
81
1.630
Why?
Protein Conformation
35
2016
859
1.610
Why?
Receptors, Cytoplasmic and Nuclear
8
2013
217
1.540
Why?
Phospholipases A
12
2007
99
1.480
Why?
Methyl-Accepting Chemotaxis Proteins
24
2015
25
1.400
Why?
Phosphatidylinositol 4,5-Diphosphate
7
2016
31
1.250
Why?
Histidine Kinase
19
2015
34
1.200
Why?
Protein Kinase C
6
2018
259
1.150
Why?
Protein Binding
26
2023
2121
1.140
Why?
Monosaccharide Transport Proteins
10
1997
49
1.130
Why?
Periplasmic Binding Proteins
9
1997
13
1.130
Why?
Guanosine Triphosphate
3
2022
92
1.090
Why?
Kinetics
34
2014
1642
1.090
Why?
Binding Sites
29
2013
1252
1.050
Why?
Protein Structure, Secondary
16
2013
341
1.040
Why?
Macrophages
5
2020
1480
0.950
Why?
Guanosine Diphosphate
2
2021
20
0.910
Why?
Electron Spin Resonance Spectroscopy
8
2012
91
0.900
Why?
Multiprotein Complexes
3
2014
155
0.890
Why?
Receptors, Cell Surface
13
2007
380
0.880
Why?
Calcium Signaling
5
2014
250
0.870
Why?
Myristoylated Alanine-Rich C Kinase Substrate
3
2018
6
0.870
Why?
Calmodulin
4
2016
76
0.860
Why?
Protein Interaction Mapping
4
2010
108
0.850
Why?
Intracellular Signaling Peptides and Proteins
2
2016
442
0.840
Why?
Phosphatidylinositols
3
2022
57
0.810
Why?
Chemoreceptor Cells
7
2007
53
0.800
Why?
Guanine Nucleotides
1
2021
15
0.750
Why?
Models, Chemical
10
2013
265
0.750
Why?
Recombinant Proteins
13
2021
1304
0.750
Why?
Cytosol
7
2007
218
0.720
Why?
Protein Engineering
19
2013
105
0.720
Why?
Class III Phosphatidylinositol 3-Kinases
1
2020
2
0.710
Why?
rab5 GTP-Binding Proteins
1
2020
6
0.710
Why?
Pseudopodia
1
2020
25
0.680
Why?
Phosphatidylserines
6
2014
88
0.670
Why?
Endosomes
1
2020
126
0.650
Why?
Spin Labels
5
2008
47
0.640
Why?
Chromatography, High Pressure Liquid
1
2021
582
0.630
Why?
Amino Acid Substitution
11
2014
282
0.590
Why?
Receptors, Platelet-Derived Growth Factor
1
2017
14
0.580
Why?
Proto-Oncogene Proteins c-akt
2
2011
431
0.580
Why?
Conserved Sequence
3
2007
227
0.560
Why?
Cytoplasm
6
2005
263
0.560
Why?
Enzyme Activation
9
2017
811
0.550
Why?
Phosphatidylinositol 3-Kinase
1
2016
26
0.540
Why?
Carrier Proteins
9
1997
743
0.530
Why?
Biochemistry
2
2007
38
0.530
Why?
Adaptor Proteins, Signal Transducing
3
2014
399
0.520
Why?
Dimerization
8
2013
192
0.520
Why?
Protein Interaction Domains and Motifs
3
2014
139
0.510
Why?
Fluorescence Resonance Energy Transfer
4
2013
177
0.510
Why?
Anion Exchange Protein 1, Erythrocyte
8
1986
22
0.500
Why?
Protein Stability
2
2014
162
0.500
Why?
Biophysics
4
2024
68
0.500
Why?
Mutation
11
2021
3717
0.490
Why?
Microscopy, Fluorescence
6
2017
400
0.470
Why?
Magnetic Resonance Spectroscopy
18
1996
539
0.460
Why?
Cystine
1
2014
17
0.460
Why?
Spectrometry, Fluorescence
9
2010
171
0.450
Why?
Eukaryotic Cells
1
2014
33
0.440
Why?
Cell Movement
3
2020
945
0.430
Why?
3-Phosphoinositide-Dependent Protein Kinases
1
2013
1
0.430
Why?
Chlorides
9
1986
139
0.430
Why?
Amino Acid Sequence
12
2016
2058
0.430
Why?
Galactose
8
1997
28
0.400
Why?
Lipid Metabolism
2
2007
497
0.400
Why?
Adaptation, Physiological
4
2020
513
0.390
Why?
Thermotoga maritima
2
2013
11
0.380
Why?
Endosomal Sorting Complexes Required for Transport
1
2012
35
0.380
Why?
Diffusion
3
2023
117
0.380
Why?
Membrane Lipids
2
2010
91
0.380
Why?
Point Mutation
3
2009
225
0.360
Why?
Vesicular Transport Proteins
1
2012
84
0.360
Why?
Amino Acid Motifs
2
2009
213
0.350
Why?
Phosphorylation
7
2021
1713
0.350
Why?
Models, Theoretical
3
2005
546
0.350
Why?
Protein Structure, Quaternary
2
2013
122
0.340
Why?
RAW 264.7 Cells
2
2020
49
0.320
Why?
Bacterial Physiological Phenomena
3
2007
57
0.310
Why?
Peptide Fragments
5
2016
692
0.300
Why?
Animals
19
2024
35360
0.300
Why?
Isoenzymes
3
2008
302
0.300
Why?
Bacteria
3
2014
820
0.300
Why?
Oncogenes
1
2008
113
0.290
Why?
Static Electricity
6
2013
116
0.290
Why?
Tryptophan
5
2014
179
0.280
Why?
Humans
36
2024
129621
0.270
Why?
Membrane Microdomains
2
2003
33
0.260
Why?
Glycine
2
2005
165
0.260
Why?
Protein Domains
2
2017
253
0.250
Why?
Cell Line
5
2018
2781
0.250
Why?
Edetic Acid
2
2003
46
0.230
Why?
Single Molecule Imaging
1
2024
35
0.220
Why?
Cell Polarity
2
2020
140
0.220
Why?
Hot Temperature
4
2021
370
0.210
Why?
Protein Kinase C beta
3
2014
21
0.210
Why?
Cations, Divalent
4
2010
56
0.210
Why?
Spin Trapping
1
2003
3
0.210
Why?
Water
3
2004
448
0.210
Why?
Recombinant Fusion Proteins
4
2010
643
0.210
Why?
Peptides
2
2000
925
0.200
Why?
Surface Properties
5
2004
399
0.200
Why?
Mice
8
2020
16937
0.200
Why?
Plasmids
5
2007
358
0.200
Why?
Electrophoresis, Polyacrylamide Gel
4
2009
330
0.200
Why?
Molecular Dynamics Simulation
4
2014
217
0.200
Why?
Phosphatidylcholines
5
2007
146
0.190
Why?
Cyclophilin A
1
2002
26
0.190
Why?
Phosphotransferases
1
2001
24
0.190
Why?
Receptors, G-Protein-Coupled
1
2004
207
0.190
Why?
Chemotactic Factors
2
2007
54
0.180
Why?
Hydrolysis
1
2021
186
0.180
Why?
Fluorescent Dyes
4
2007
317
0.180
Why?
Spectrophotometry, Ultraviolet
1
2021
84
0.180
Why?
Reproducibility of Results
3
2021
3083
0.180
Why?
Aspartate Kinase
1
2000
1
0.180
Why?
Metals
3
1997
128
0.180
Why?
Molecular Sequence Data
6
2005
2832
0.170
Why?
Intracellular Membranes
1
2020
83
0.170
Why?
Diclofenac
1
2020
15
0.170
Why?
Glutamic Acid
3
2011
237
0.170
Why?
Time-Lapse Imaging
1
2020
20
0.170
Why?
Chelating Agents
2
1997
68
0.170
Why?
Lymphocyte Antigen 96
2
2010
24
0.170
Why?
Ibuprofen
1
2020
81
0.160
Why?
Endocytosis
1
2020
163
0.160
Why?
Alanine
2
2013
142
0.160
Why?
Troponin C
1
1998
5
0.160
Why?
Ultraviolet Rays
1
2021
383
0.150
Why?
Oxidation-Reduction
3
2010
1033
0.150
Why?
Membranes, Artificial
1
1998
70
0.150
Why?
Thermodynamics
6
2002
408
0.150
Why?
Crystallography, X-Ray
3
2013
436
0.150
Why?
Phospholipases A2
5
2006
79
0.150
Why?
Phosphopeptides
1
2017
18
0.140
Why?
Synaptotagmins
2
2012
20
0.140
Why?
Acetaminophen
1
2020
246
0.140
Why?
Solvents
4
1999
108
0.140
Why?
Terbium
2
1996
4
0.140
Why?
Biophysical Phenomena
3
2010
64
0.140
Why?
Sf9 Cells
1
2016
9
0.140
Why?
Aspirin
1
2020
380
0.140
Why?
Spodoptera
1
2016
37
0.130
Why?
Magnesium
3
1998
153
0.130
Why?
Leukocytes
1
2018
304
0.130
Why?
Ligands
5
2010
622
0.130
Why?
Structure-Activity Relationship
6
2013
548
0.130
Why?
Fluorine Radioisotopes
1
1996
11
0.130
Why?
Cloning, Molecular
5
1997
524
0.130
Why?
Cattle
2
2008
976
0.120
Why?
Erythrocyte Membrane
8
1986
49
0.120
Why?
Group IV Phospholipases A2
3
2006
47
0.120
Why?
Fluorine
5
1993
15
0.120
Why?
Macromolecular Substances
3
2010
213
0.120
Why?
Osmolar Concentration
3
2009
166
0.120
Why?
Glutathione Transferase
2
2007
101
0.120
Why?
Substrate Specificity
3
2008
368
0.120
Why?
Protein Transport
2
2007
428
0.120
Why?
Hydrophobic and Hydrophilic Interactions
2
2012
186
0.120
Why?
Protein Isoforms
2
2013
391
0.110
Why?
Microarray Analysis
1
2014
122
0.110
Why?
Bacteriorhodopsins
2
2005
11
0.110
Why?
Phospholipids
2
2013
215
0.110
Why?
Hydrogen-Ion Concentration
4
2009
544
0.110
Why?
Immunity, Innate
1
2020
804
0.110
Why?
Models, Biological
6
2007
1721
0.110
Why?
Neoplasms
1
2008
2470
0.110
Why?
Biological Transport, Active
7
1986
78
0.110
Why?
Protein Folding
3
2002
266
0.110
Why?
Proteolysis
1
2014
166
0.110
Why?
Histidine
2
2007
60
0.110
Why?
Protein Denaturation
3
2002
75
0.110
Why?
Phospholipases A2, Cytosolic
1
2013
6
0.110
Why?
Nuclear Magnetic Resonance, Biomolecular
2
2007
257
0.110
Why?
Protein Multimerization
1
2014
179
0.100
Why?
Myocardium
1
1998
980
0.100
Why?
Fibroblasts
1
2018
948
0.100
Why?
Molecular Docking Simulation
1
2013
109
0.100
Why?
Mutagenesis
1
2013
181
0.100
Why?
Trypsin
1
2012
74
0.100
Why?
Synaptotagmin I
1
2012
13
0.100
Why?
Multienzyme Complexes
1
2012
68
0.100
Why?
Bacterial Outer Membrane Proteins
1
2012
58
0.100
Why?
Computer Simulation
5
2013
943
0.100
Why?
Molecular Structure
4
1996
482
0.100
Why?
Myosin-Light-Chain Kinase
1
2012
20
0.100
Why?
Transfection
2
2011
911
0.100
Why?
NIH 3T3 Cells
1
2011
141
0.090
Why?
Energy Transfer
2
2002
51
0.090
Why?
Fluoresceins
2
2003
48
0.090
Why?
Time Factors
2
2016
6556
0.090
Why?
Carbohydrate Metabolism
1
1991
62
0.090
Why?
In Vitro Techniques
3
2003
1085
0.090
Why?
Facilitated Diffusion
1
2010
3
0.090
Why?
Hydrodynamics
1
2010
40
0.090
Why?
Toll-Like Receptor 4
2
2010
263
0.090
Why?
Niflumic Acid
2
1986
3
0.090
Why?
Sequence Homology, Amino Acid
2
2004
372
0.080
Why?
Heterocyclic Compounds, 3-Ring
1
2010
31
0.080
Why?
Toll-Like Receptors
1
2010
179
0.080
Why?
Crystallization
2
2013
138
0.080
Why?
Single-Cell Analysis
1
2011
277
0.080
Why?
Methyltransferases
1
2009
70
0.080
Why?
Photobleaching
1
2009
23
0.080
Why?
Least-Squares Analysis
1
2009
78
0.080
Why?
3T3 Cells
1
2008
153
0.080
Why?
Cations
2
2002
80
0.080
Why?
Hydrogen Bonding
2
2014
149
0.070
Why?
Blood Proteins
2
2013
242
0.070
Why?
Ethylmaleimide
2
2003
18
0.070
Why?
Receptors, Neurotransmitter
1
1987
17
0.070
Why?
Phosphoproteins
2
2013
332
0.070
Why?
Sensory Receptor Cells
1
1988
103
0.070
Why?
Archaeal Proteins
1
2007
49
0.070
Why?
Cell Survival
2
2008
1086
0.070
Why?
Nicotinic Acids
1
1986
6
0.070
Why?
Oligonucleotide Probes
1
2007
50
0.070
Why?
Benzenesulfonates
1
1986
19
0.070
Why?
Feedback
1
2007
162
0.070
Why?
Oxadiazoles
1
1986
33
0.070
Why?
Taurine
1
1986
43
0.070
Why?
Lysine
1
2008
286
0.060
Why?
Methylation
2
1997
230
0.060
Why?
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
1
1985
12
0.060
Why?
Structural Homology, Protein
1
2005
25
0.060
Why?
Calcium Channel Blockers
1
1986
161
0.060
Why?
Swine
1
2008
760
0.060
Why?
Drug Delivery Systems
1
2008
336
0.060
Why?
Actins
1
2007
411
0.060
Why?
Organometallic Compounds
2
2000
107
0.060
Why?
Motion
2
1996
98
0.060
Why?
Sequence Homology
1
2004
40
0.060
Why?
Phosphatidylethanolamines
2
2002
74
0.060
Why?
Analgesics, Opioid
2
2010
913
0.060
Why?
Mathematics
4
1985
102
0.060
Why?
Dogs
1
2005
381
0.060
Why?
Halobacterium
1
1984
3
0.060
Why?
Periplasm
1
2004
11
0.060
Why?
Membrane Potentials
1
2005
293
0.060
Why?
Rhodopsin
1
2004
10
0.060
Why?
Carotenoids
1
1984
39
0.060
Why?
Liposomes
2
2012
168
0.050
Why?
Lipopolysaccharides
1
2007
875
0.050
Why?
Computer Graphics
2
1996
41
0.050
Why?
Rhodamines
1
2003
18
0.050
Why?
Cyclic N-Oxides
1
2003
30
0.050
Why?
Data Interpretation, Statistical
1
2004
335
0.050
Why?
Fluorescein
1
2003
25
0.050
Why?
Peptide Library
1
2003
84
0.050
Why?
Urea
1
2002
77
0.050
Why?
Glucose
3
1992
1003
0.050
Why?
Peptide Hydrolases
1
2003
107
0.050
Why?
Dansyl Compounds
1
2002
5
0.050
Why?
Sulfhydryl Compounds
2
1998
187
0.050
Why?
Catalysis
1
2002
310
0.040
Why?
Lipids
1
2005
625
0.040
Why?
Proteins
1
2007
942
0.040
Why?
Nitrogen
1
2002
167
0.040
Why?
Chlorine
3
1985
58
0.040
Why?
Stilbenes
3
1985
36
0.040
Why?
Arginine
1
2002
265
0.040
Why?
Nitrilotriacetic Acid
1
2000
1
0.040
Why?
Benzoxazoles
1
1980
20
0.040
Why?
Chromatography, Affinity
1
2000
83
0.040
Why?
Indicators and Reagents
1
2000
109
0.040
Why?
Nickel
1
2000
54
0.040
Why?
Sequence Alignment
2
1998
332
0.040
Why?
Staining and Labeling
1
1980
141
0.040
Why?
Iodides
1
1998
6
0.040
Why?
Pyrimidinones
1
1980
103
0.040
Why?
Naphthalenesulfonates
1
1998
7
0.040
Why?
Fluorescence Polarization
1
1998
38
0.040
Why?
Isotopes
2
1991
32
0.040
Why?
Muscles
1
1980
322
0.040
Why?
Membrane Glycoproteins
1
2001
474
0.040
Why?
Chickens
1
1998
188
0.040
Why?
Pain Measurement
2
2010
506
0.030
Why?
Nerve Tissue Proteins
1
2001
570
0.030
Why?
Sequence Analysis
1
1996
37
0.030
Why?
Solubility
1
1997
235
0.030
Why?
Strontium
2
1998
14
0.030
Why?
Chemistry, Physical
1
1996
37
0.030
Why?
Chemical Phenomena
1
1996
81
0.030
Why?
Models, Structural
1
1995
39
0.030
Why?
Tetrahydrofolate Dehydrogenase
1
1996
23
0.030
Why?
L-Lactate Dehydrogenase
1
1996
119
0.030
Why?
Genetic Engineering
1
1996
88
0.030
Why?
Flagella
1
1995
19
0.030
Why?
Anions
2
1985
31
0.030
Why?
Genes, Bacterial
1
1995
157
0.030
Why?
p-Fluorophenylalanine
1
1994
2
0.030
Why?
Glutamates
1
1994
56
0.030
Why?
Electrons
1
2014
79
0.030
Why?
Cations, Monovalent
1
1993
6
0.030
Why?
Carboxylic Acids
1
1993
32
0.030
Why?
Movement
1
1995
269
0.030
Why?
Cryoelectron Microscopy
1
2014
178
0.030
Why?
Iodoacetamide
1
1992
5
0.030
Why?
Trehalose
1
2012
30
0.020
Why?
Organophosphates
1
1993
120
0.020
Why?
Gadolinium
1
1991
78
0.020
Why?
Molecular Conformation
1
1991
144
0.020
Why?
Rats
2
2010
5499
0.020
Why?
Lac Operon
1
1990
45
0.020
Why?
Infusion Pumps
1
2009
31
0.020
Why?
Toll-Like Receptor 2
1
2010
113
0.020
Why?
Myeloid Differentiation Factor 88
1
2010
96
0.020
Why?
Injections, Spinal
1
2009
109
0.020
Why?
Receptors, Opioid, mu
1
2009
65
0.020
Why?
Morphine
1
2010
137
0.020
Why?
Gene Expression Regulation, Bacterial
1
1991
324
0.020
Why?
Hyperalgesia
1
2009
124
0.020
Why?
Naloxone
1
2009
112
0.020
Why?
Analgesia
1
2009
100
0.020
Why?
Microglia
1
2010
235
0.020
Why?
Reaction Time
1
2009
410
0.020
Why?
Narcotic Antagonists
1
2009
164
0.020
Why?
Allosteric Regulation
1
1987
99
0.020
Why?
Species Specificity
1
1988
575
0.020
Why?
Substance Withdrawal Syndrome
1
2009
176
0.020
Why?
Mice, Inbred BALB C
1
2010
1245
0.020
Why?
Dinitrofluorobenzene
1
1986
6
0.020
Why?
Cyclohexanones
1
1986
9
0.020
Why?
Dipyridamole
1
1986
28
0.020
Why?
Cell Fractionation
1
1986
56
0.020
Why?
Phenylglyoxal
1
1985
1
0.020
Why?
Papain
1
1985
5
0.020
Why?
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid
1
1985
8
0.020
Why?
Interleukin-1
1
2010
958
0.020
Why?
Chymotrypsin
1
1985
19
0.020
Why?
Bromine
1
1985
6
0.020
Why?
Sonication
1
1985
13
0.020
Why?
Bicarbonates
1
1985
42
0.020
Why?
Promoter Regions, Genetic
1
1990
1207
0.020
Why?
Tumor Necrosis Factor-alpha
1
2010
1198
0.010
Why?
Muscle, Skeletal
1
1994
1614
0.010
Why?
Biological Transport
1
1985
401
0.010
Why?
Cytoskeleton
1
1985
183
0.010
Why?
Halorhodopsins
1
1984
1
0.010
Why?
Bromides
1
1984
5
0.010
Why?
Radioisotopes
1
1984
31
0.010
Why?
Cold Temperature
1
1985
155
0.010
Why?
Binding, Competitive
1
1984
206
0.010
Why?
Rats, Sprague-Dawley
1
2009
2406
0.010
Why?
Mice, Knockout
1
2010
2871
0.010
Why?
Cells, Cultured
1
2010
4083
0.010
Why?
Chick Embryo
1
1980
130
0.010
Why?
Cell Membrane Permeability
1
1980
81
0.010
Why?
Barium
1
1998
28
0.010
Why?
CHO Cells
1
1998
153
0.010
Why?
COS Cells
1
1998
185
0.010
Why?
Cricetinae
1
1998
277
0.010
Why?
Blood Glucose
1
1986
2097
0.010
Why?
Male
2
2010
63674
0.010
Why?
Cytochalasin B
1
1986
17
0.000
Why?
Falke's Networks
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