Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joseph Falke

Concepts (378)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Chemotaxis
43
2018
130
6.760
Why?
Membrane Proteins
45
2018
1118
5.240
Why?
Bacterial Proteins
40
2015
837
4.330
Why?
Receptors, Amino Acid
23
2009
25
3.710
Why?
Signal Transduction
42
2024
4916
3.560
Why?
ras Proteins
5
2024
143
3.470
Why?
Protein Kinase C-alpha
11
2023
37
3.170
Why?
Protein Kinases
18
2014
314
2.960
Why?
Lipid Bilayers
15
2023
97
2.850
Why?
Cell Membrane
24
2021
733
2.750
Why?
Disulfides
21
2014
97
2.650
Why?
Calcium
26
2018
1208
2.540
Why?
Escherichia coli Proteins
23
2015
179
2.480
Why?
Phosphatidylinositol 3-Kinases
5
2022
353
2.180
Why?
Protein Structure, Tertiary
33
2015
842
1.890
Why?
Escherichia coli
33
2015
766
1.730
Why?
Salmonella typhimurium
20
2014
174
1.720
Why?
Phosphatidylinositol Phosphates
6
2017
39
1.690
Why?
Mutagenesis, Site-Directed
27
2014
363
1.660
Why?
Calcium-Binding Proteins
17
2003
212
1.650
Why?
Models, Molecular
43
2017
1487
1.630
Why?
Cysteine
20
2009
195
1.620
Why?
Aspartic Acid
16
2009
80
1.610
Why?
Protein Conformation
35
2016
861
1.600
Why?
Receptors, Cytoplasmic and Nuclear
8
2013
216
1.530
Why?
Phospholipases A
12
2007
98
1.470
Why?
Methyl-Accepting Chemotaxis Proteins
24
2015
25
1.380
Why?
Phosphatidylinositol 4,5-Diphosphate
7
2016
31
1.230
Why?
Histidine Kinase
19
2015
34
1.190
Why?
Protein Kinase C
6
2018
261
1.140
Why?
Protein Binding
26
2023
2121
1.140
Why?
Monosaccharide Transport Proteins
10
1997
49
1.120
Why?
Periplasmic Binding Proteins
9
1997
13
1.120
Why?
Guanosine Triphosphate
3
2022
91
1.080
Why?
Kinetics
34
2014
1641
1.080
Why?
Binding Sites
29
2013
1250
1.040
Why?
Protein Structure, Secondary
16
2013
342
1.030
Why?
Macrophages
5
2020
1486
0.940
Why?
Guanosine Diphosphate
2
2021
20
0.900
Why?
Electron Spin Resonance Spectroscopy
8
2012
91
0.890
Why?
Multiprotein Complexes
3
2014
154
0.880
Why?
Receptors, Cell Surface
13
2007
381
0.870
Why?
Calcium Signaling
5
2014
251
0.860
Why?
Myristoylated Alanine-Rich C Kinase Substrate
3
2018
6
0.860
Why?
Calmodulin
4
2016
76
0.850
Why?
Protein Interaction Mapping
4
2010
107
0.840
Why?
Intracellular Signaling Peptides and Proteins
2
2016
443
0.830
Why?
Phosphatidylinositols
3
2022
57
0.800
Why?
Chemoreceptor Cells
7
2007
54
0.790
Why?
Models, Chemical
10
2013
264
0.750
Why?
Guanine Nucleotides
1
2021
15
0.740
Why?
Recombinant Proteins
13
2021
1311
0.740
Why?
Cytosol
7
2007
219
0.720
Why?
Protein Engineering
19
2013
106
0.710
Why?
Class III Phosphatidylinositol 3-Kinases
1
2020
2
0.710
Why?
rab5 GTP-Binding Proteins
1
2020
6
0.700
Why?
Pseudopodia
1
2020
25
0.670
Why?
Phosphatidylserines
6
2014
88
0.660
Why?
Endosomes
1
2020
126
0.640
Why?
Spin Labels
5
2008
46
0.630
Why?
Chromatography, High Pressure Liquid
1
2021
584
0.620
Why?
Amino Acid Substitution
11
2014
284
0.580
Why?
Receptors, Platelet-Derived Growth Factor
1
2017
14
0.570
Why?
Proto-Oncogene Proteins c-akt
2
2011
427
0.570
Why?
Conserved Sequence
3
2007
227
0.560
Why?
Enzyme Activation
9
2017
806
0.550
Why?
Cytoplasm
6
2005
268
0.550
Why?
Phosphatidylinositol 3-Kinase
1
2016
26
0.530
Why?
Carrier Proteins
9
1997
740
0.530
Why?
Biochemistry
2
2007
38
0.520
Why?
Adaptor Proteins, Signal Transducing
3
2014
398
0.520
Why?
Dimerization
8
2013
193
0.510
Why?
Fluorescence Resonance Energy Transfer
4
2013
175
0.500
Why?
Protein Interaction Domains and Motifs
3
2014
139
0.500
Why?
Anion Exchange Protein 1, Erythrocyte
8
1986
22
0.490
Why?
Protein Stability
2
2014
162
0.490
Why?
Biophysics
4
2024
66
0.490
Why?
Mutation
11
2021
3702
0.480
Why?
Microscopy, Fluorescence
6
2017
397
0.460
Why?
Magnetic Resonance Spectroscopy
18
1996
541
0.460
Why?
Cystine
1
2014
17
0.460
Why?
Spectrometry, Fluorescence
9
2010
164
0.450
Why?
Eukaryotic Cells
1
2014
30
0.430
Why?
Cell Movement
3
2020
942
0.430
Why?
3-Phosphoinositide-Dependent Protein Kinases
1
2013
1
0.430
Why?
Chlorides
9
1986
139
0.420
Why?
Amino Acid Sequence
12
2016
2055
0.420
Why?
Galactose
8
1997
27
0.400
Why?
Lipid Metabolism
2
2007
500
0.390
Why?
Adaptation, Physiological
4
2020
520
0.380
Why?
Thermotoga maritima
2
2013
11
0.380
Why?
Endosomal Sorting Complexes Required for Transport
1
2012
35
0.380
Why?
Diffusion
3
2023
117
0.370
Why?
Membrane Lipids
2
2010
91
0.370
Why?
Point Mutation
3
2009
224
0.360
Why?
Vesicular Transport Proteins
1
2012
84
0.360
Why?
Amino Acid Motifs
2
2009
215
0.350
Why?
Phosphorylation
7
2021
1714
0.350
Why?
Models, Theoretical
3
2005
548
0.350
Why?
Protein Structure, Quaternary
2
2013
121
0.330
Why?
RAW 264.7 Cells
2
2020
49
0.310
Why?
Bacterial Physiological Phenomena
3
2007
58
0.310
Why?
Animals
19
2024
35334
0.300
Why?
Peptide Fragments
5
2016
695
0.300
Why?
Isoenzymes
3
2008
300
0.300
Why?
Bacteria
3
2014
812
0.290
Why?
Oncogenes
1
2008
110
0.290
Why?
Static Electricity
6
2013
117
0.280
Why?
Tryptophan
5
2014
177
0.280
Why?
Humans
36
2024
129527
0.270
Why?
Membrane Microdomains
2
2003
33
0.260
Why?
Glycine
2
2005
166
0.250
Why?
Protein Domains
2
2017
254
0.250
Why?
Cell Line
5
2018
2774
0.240
Why?
Edetic Acid
2
2003
49
0.230
Why?
Single Molecule Imaging
1
2024
36
0.220
Why?
Cell Polarity
2
2020
137
0.220
Why?
Hot Temperature
4
2021
369
0.210
Why?
Protein Kinase C beta
3
2014
21
0.210
Why?
Cations, Divalent
4
2010
53
0.210
Why?
Spin Trapping
1
2003
3
0.210
Why?
Water
3
2004
442
0.210
Why?
Recombinant Fusion Proteins
4
2010
650
0.200
Why?
Peptides
2
2000
925
0.200
Why?
Surface Properties
5
2004
400
0.200
Why?
Mice
8
2020
16973
0.200
Why?
Plasmids
5
2007
354
0.200
Why?
Electrophoresis, Polyacrylamide Gel
4
2009
338
0.200
Why?
Molecular Dynamics Simulation
4
2014
217
0.200
Why?
Phosphatidylcholines
5
2007
145
0.190
Why?
Cyclophilin A
1
2002
26
0.190
Why?
Phosphotransferases
1
2001
24
0.190
Why?
Receptors, G-Protein-Coupled
1
2004
206
0.190
Why?
Chemotactic Factors
2
2007
55
0.180
Why?
Fluorescent Dyes
4
2007
312
0.180
Why?
Hydrolysis
1
2021
186
0.180
Why?
Spectrophotometry, Ultraviolet
1
2021
84
0.180
Why?
Reproducibility of Results
3
2021
3081
0.180
Why?
Metals
3
1997
123
0.170
Why?
Aspartate Kinase
1
2000
1
0.170
Why?
Molecular Sequence Data
6
2005
2827
0.170
Why?
Intracellular Membranes
1
2020
83
0.170
Why?
Glutamic Acid
3
2011
235
0.170
Why?
Diclofenac
1
2020
15
0.170
Why?
Time-Lapse Imaging
1
2020
20
0.170
Why?
Chelating Agents
2
1997
69
0.160
Why?
Lymphocyte Antigen 96
2
2010
24
0.160
Why?
Ibuprofen
1
2020
81
0.160
Why?
Endocytosis
1
2020
162
0.160
Why?
Alanine
2
2013
143
0.150
Why?
Troponin C
1
1998
5
0.150
Why?
Ultraviolet Rays
1
2021
383
0.150
Why?
Oxidation-Reduction
3
2010
1029
0.150
Why?
Membranes, Artificial
1
1998
71
0.150
Why?
Thermodynamics
6
2002
407
0.150
Why?
Crystallography, X-Ray
3
2013
438
0.150
Why?
Phospholipases A2
5
2006
78
0.140
Why?
Phosphopeptides
1
2017
18
0.140
Why?
Synaptotagmins
2
2012
20
0.140
Why?
Acetaminophen
1
2020
248
0.140
Why?
Solvents
4
1999
107
0.140
Why?
Terbium
2
1996
4
0.140
Why?
Biophysical Phenomena
3
2010
64
0.130
Why?
Sf9 Cells
1
2016
9
0.130
Why?
Aspirin
1
2020
378
0.130
Why?
Spodoptera
1
2016
37
0.130
Why?
Magnesium
3
1998
154
0.130
Why?
Leukocytes
1
2018
304
0.130
Why?
Ligands
5
2010
619
0.130
Why?
Structure-Activity Relationship
6
2013
548
0.130
Why?
Cloning, Molecular
5
1997
524
0.130
Why?
Fluorine Radioisotopes
1
1996
12
0.130
Why?
Cattle
2
2008
959
0.120
Why?
Erythrocyte Membrane
8
1986
53
0.120
Why?
Group IV Phospholipases A2
3
2006
47
0.120
Why?
Fluorine
5
1993
14
0.120
Why?
Macromolecular Substances
3
2010
216
0.120
Why?
Osmolar Concentration
3
2009
167
0.120
Why?
Glutathione Transferase
2
2007
102
0.120
Why?
Substrate Specificity
3
2008
371
0.110
Why?
Protein Transport
2
2007
428
0.110
Why?
Protein Isoforms
2
2013
392
0.110
Why?
Hydrophobic and Hydrophilic Interactions
2
2012
185
0.110
Why?
Microarray Analysis
1
2014
113
0.110
Why?
Bacteriorhodopsins
2
2005
11
0.110
Why?
Phospholipids
2
2013
215
0.110
Why?
Hydrogen-Ion Concentration
4
2009
539
0.110
Why?
Immunity, Innate
1
2020
804
0.110
Why?
Models, Biological
6
2007
1717
0.110
Why?
Neoplasms
1
2008
2450
0.110
Why?
Protein Folding
3
2002
265
0.110
Why?
Biological Transport, Active
7
1986
78
0.110
Why?
Proteolysis
1
2014
167
0.110
Why?
Histidine
2
2007
60
0.110
Why?
Protein Denaturation
3
2002
74
0.110
Why?
Phospholipases A2, Cytosolic
1
2013
7
0.100
Why?
Nuclear Magnetic Resonance, Biomolecular
2
2007
260
0.100
Why?
Myocardium
1
1998
981
0.100
Why?
Protein Multimerization
1
2014
179
0.100
Why?
Fibroblasts
1
2018
943
0.100
Why?
Molecular Docking Simulation
1
2013
109
0.100
Why?
Mutagenesis
1
2013
178
0.100
Why?
Trypsin
1
2012
74
0.100
Why?
Synaptotagmin I
1
2012
13
0.100
Why?
Multienzyme Complexes
1
2012
68
0.100
Why?
Computer Simulation
5
2013
937
0.100
Why?
Bacterial Outer Membrane Proteins
1
2012
59
0.100
Why?
Molecular Structure
4
1996
482
0.100
Why?
Myosin-Light-Chain Kinase
1
2012
20
0.100
Why?
Transfection
2
2011
916
0.100
Why?
NIH 3T3 Cells
1
2011
140
0.090
Why?
Energy Transfer
2
2002
46
0.090
Why?
Time Factors
2
2016
6530
0.090
Why?
Fluoresceins
2
2003
46
0.090
Why?
Carbohydrate Metabolism
1
1991
61
0.090
Why?
In Vitro Techniques
3
2003
1091
0.090
Why?
Facilitated Diffusion
1
2010
3
0.090
Why?
Toll-Like Receptor 4
2
2010
264
0.090
Why?
Hydrodynamics
1
2010
40
0.090
Why?
Niflumic Acid
2
1986
3
0.080
Why?
Sequence Homology, Amino Acid
2
2004
371
0.080
Why?
Heterocyclic Compounds, 3-Ring
1
2010
31
0.080
Why?
Toll-Like Receptors
1
2010
179
0.080
Why?
Crystallization
2
2013
137
0.080
Why?
Single-Cell Analysis
1
2011
274
0.080
Why?
Methyltransferases
1
2009
70
0.080
Why?
Photobleaching
1
2009
23
0.080
Why?
Least-Squares Analysis
1
2009
78
0.080
Why?
3T3 Cells
1
2008
159
0.080
Why?
Cations
2
2002
80
0.070
Why?
Hydrogen Bonding
2
2014
149
0.070
Why?
Blood Proteins
2
2013
244
0.070
Why?
Ethylmaleimide
2
2003
18
0.070
Why?
Receptors, Neurotransmitter
1
1987
17
0.070
Why?
Phosphoproteins
2
2013
333
0.070
Why?
Sensory Receptor Cells
1
1988
103
0.070
Why?
Archaeal Proteins
1
2007
48
0.070
Why?
Cell Survival
2
2008
1084
0.070
Why?
Nicotinic Acids
1
1986
5
0.070
Why?
Oligonucleotide Probes
1
2007
49
0.070
Why?
Benzenesulfonates
1
1986
20
0.070
Why?
Feedback
1
2007
162
0.070
Why?
Oxadiazoles
1
1986
32
0.070
Why?
Taurine
1
1986
43
0.060
Why?
Lysine
1
2008
286
0.060
Why?
Methylation
2
1997
228
0.060
Why?
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
1
1985
12
0.060
Why?
Structural Homology, Protein
1
2005
24
0.060
Why?
Calcium Channel Blockers
1
1986
160
0.060
Why?
Swine
1
2008
760
0.060
Why?
Actins
1
2007
406
0.060
Why?
Drug Delivery Systems
1
2008
337
0.060
Why?
Organometallic Compounds
2
2000
106
0.060
Why?
Motion
2
1996
98
0.060
Why?
Sequence Homology
1
2004
39
0.060
Why?
Phosphatidylethanolamines
2
2002
74
0.060
Why?
Analgesics, Opioid
2
2010
919
0.060
Why?
Mathematics
4
1985
103
0.060
Why?
Dogs
1
2005
385
0.060
Why?
Halobacterium
1
1984
3
0.060
Why?
Periplasm
1
2004
11
0.060
Why?
Membrane Potentials
1
2005
292
0.050
Why?
Rhodopsin
1
2004
11
0.050
Why?
Carotenoids
1
1984
41
0.050
Why?
Liposomes
2
2012
171
0.050
Why?
Lipopolysaccharides
1
2007
872
0.050
Why?
Computer Graphics
2
1996
41
0.050
Why?
Rhodamines
1
2003
18
0.050
Why?
Cyclic N-Oxides
1
2003
29
0.050
Why?
Data Interpretation, Statistical
1
2004
337
0.050
Why?
Fluorescein
1
2003
25
0.050
Why?
Peptide Library
1
2003
84
0.050
Why?
Urea
1
2002
76
0.050
Why?
Glucose
3
1992
996
0.050
Why?
Sulfhydryl Compounds
2
1998
187
0.050
Why?
Peptide Hydrolases
1
2003
108
0.050
Why?
Dansyl Compounds
1
2002
5
0.050
Why?
Lipids
1
2005
614
0.040
Why?
Catalysis
1
2002
311
0.040
Why?
Proteins
1
2007
944
0.040
Why?
Nitrogen
1
2002
162
0.040
Why?
Chlorine
3
1985
59
0.040
Why?
Stilbenes
3
1985
36
0.040
Why?
Arginine
1
2002
262
0.040
Why?
Nitrilotriacetic Acid
1
2000
1
0.040
Why?
Benzoxazoles
1
1980
20
0.040
Why?
Chromatography, Affinity
1
2000
83
0.040
Why?
Indicators and Reagents
1
2000
108
0.040
Why?
Nickel
1
2000
54
0.040
Why?
Sequence Alignment
2
1998
330
0.040
Why?
Staining and Labeling
1
1980
143
0.040
Why?
Iodides
1
1998
6
0.040
Why?
Pyrimidinones
1
1980
102
0.040
Why?
Naphthalenesulfonates
1
1998
7
0.040
Why?
Fluorescence Polarization
1
1998
38
0.040
Why?
Isotopes
2
1991
32
0.040
Why?
Muscles
1
1980
320
0.040
Why?
Membrane Glycoproteins
1
2001
477
0.040
Why?
Chickens
1
1998
187
0.040
Why?
Pain Measurement
2
2010
507
0.030
Why?
Nerve Tissue Proteins
1
2001
569
0.030
Why?
Sequence Analysis
1
1996
36
0.030
Why?
Solubility
1
1997
232
0.030
Why?
Strontium
2
1998
14
0.030
Why?
Chemistry, Physical
1
1996
37
0.030
Why?
Chemical Phenomena
1
1996
82
0.030
Why?
Models, Structural
1
1995
39
0.030
Why?
Tetrahydrofolate Dehydrogenase
1
1996
23
0.030
Why?
L-Lactate Dehydrogenase
1
1996
119
0.030
Why?
Genetic Engineering
1
1996
87
0.030
Why?
Flagella
1
1995
19
0.030
Why?
Anions
2
1985
31
0.030
Why?
Genes, Bacterial
1
1995
159
0.030
Why?
p-Fluorophenylalanine
1
1994
2
0.030
Why?
Glutamates
1
1994
57
0.030
Why?
Electrons
1
2014
77
0.030
Why?
Cations, Monovalent
1
1993
6
0.030
Why?
Movement
1
1995
266
0.030
Why?
Carboxylic Acids
1
1993
33
0.030
Why?
Cryoelectron Microscopy
1
2014
178
0.030
Why?
Iodoacetamide
1
1992
5
0.030
Why?
Trehalose
1
2012
31
0.020
Why?
Organophosphates
1
1993
122
0.020
Why?
Rats
2
2010
5470
0.020
Why?
Gadolinium
1
1991
78
0.020
Why?
Molecular Conformation
1
1991
141
0.020
Why?
Lac Operon
1
1990
46
0.020
Why?
Infusion Pumps
1
2009
32
0.020
Why?
Toll-Like Receptor 2
1
2010
113
0.020
Why?
Myeloid Differentiation Factor 88
1
2010
97
0.020
Why?
Injections, Spinal
1
2009
105
0.020
Why?
Receptors, Opioid, mu
1
2009
66
0.020
Why?
Morphine
1
2010
138
0.020
Why?
Gene Expression Regulation, Bacterial
1
1991
324
0.020
Why?
Hyperalgesia
1
2009
121
0.020
Why?
Naloxone
1
2009
112
0.020
Why?
Analgesia
1
2009
104
0.020
Why?
Microglia
1
2010
234
0.020
Why?
Reaction Time
1
2009
411
0.020
Why?
Narcotic Antagonists
1
2009
164
0.020
Why?
Allosteric Regulation
1
1987
94
0.020
Why?
Species Specificity
1
1988
568
0.020
Why?
Substance Withdrawal Syndrome
1
2009
175
0.020
Why?
Mice, Inbred BALB C
1
2010
1248
0.020
Why?
Dinitrofluorobenzene
1
1986
6
0.020
Why?
Cyclohexanones
1
1986
9
0.020
Why?
Dipyridamole
1
1986
28
0.020
Why?
Cell Fractionation
1
1986
56
0.020
Why?
Phenylglyoxal
1
1985
1
0.020
Why?
Papain
1
1985
5
0.020
Why?
Interleukin-1
1
2010
954
0.020
Why?
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid
1
1985
8
0.020
Why?
Chymotrypsin
1
1985
19
0.020
Why?
Bromine
1
1985
5
0.020
Why?
Sonication
1
1985
13
0.020
Why?
Bicarbonates
1
1985
42
0.020
Why?
Promoter Regions, Genetic
1
1990
1211
0.020
Why?
Tumor Necrosis Factor-alpha
1
2010
1203
0.010
Why?
Muscle, Skeletal
1
1994
1636
0.010
Why?
Biological Transport
1
1985
405
0.010
Why?
Cytoskeleton
1
1985
181
0.010
Why?
Halorhodopsins
1
1984
1
0.010
Why?
Bromides
1
1984
5
0.010
Why?
Cold Temperature
1
1985
155
0.010
Why?
Radioisotopes
1
1984
30
0.010
Why?
Binding, Competitive
1
1984
206
0.010
Why?
Rats, Sprague-Dawley
1
2009
2393
0.010
Why?
Mice, Knockout
1
2010
2887
0.010
Why?
Cells, Cultured
1
2010
4087
0.010
Why?
Chick Embryo
1
1980
130
0.010
Why?
Cell Membrane Permeability
1
1980
82
0.010
Why?
Barium
1
1998
28
0.010
Why?
CHO Cells
1
1998
155
0.010
Why?
COS Cells
1
1998
185
0.010
Why?
Cricetinae
1
1998
280
0.010
Why?
Blood Glucose
1
1986
2071
0.010
Why?
Male
2
2010
63586
0.010
Why?
Cytochalasin B
1
1986
17
0.000
Why?
Falke's Networks
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