Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joseph Falke

Concepts (378)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Chemotaxis
43
2018
130
6.700
Why?
Membrane Proteins
45
2018
1163
5.100
Why?
Bacterial Proteins
40
2015
872
4.240
Why?
Receptors, Amino Acid
23
2009
25
3.690
Why?
Signal Transduction
42
2024
5077
3.490
Why?
ras Proteins
5
2024
153
3.430
Why?
Protein Kinase C-alpha
11
2023
37
3.150
Why?
Protein Kinases
18
2014
319
2.930
Why?
Lipid Bilayers
15
2023
97
2.830
Why?
Cell Membrane
24
2021
735
2.740
Why?
Disulfides
21
2014
107
2.620
Why?
Calcium
26
2018
1197
2.530
Why?
Escherichia coli Proteins
23
2015
194
2.410
Why?
Phosphatidylinositol 3-Kinases
5
2022
366
2.150
Why?
Protein Structure, Tertiary
33
2015
860
1.870
Why?
Salmonella typhimurium
20
2014
183
1.690
Why?
Escherichia coli
33
2015
807
1.690
Why?
Phosphatidylinositol Phosphates
6
2017
39
1.680
Why?
Mutagenesis, Site-Directed
27
2014
374
1.650
Why?
Calcium-Binding Proteins
17
2003
218
1.640
Why?
Cysteine
20
2009
204
1.600
Why?
Aspartic Acid
16
2009
79
1.600
Why?
Models, Molecular
43
2017
1569
1.590
Why?
Protein Conformation
35
2016
933
1.550
Why?
Receptors, Cytoplasmic and Nuclear
8
2013
219
1.520
Why?
Phospholipases A
12
2007
102
1.460
Why?
Methyl-Accepting Chemotaxis Proteins
24
2015
25
1.370
Why?
Phosphatidylinositol 4,5-Diphosphate
7
2016
32
1.230
Why?
Histidine Kinase
19
2015
34
1.180
Why?
Protein Kinase C
6
2018
261
1.130
Why?
Protein Binding
26
2023
2216
1.110
Why?
Periplasmic Binding Proteins
9
1997
13
1.110
Why?
Monosaccharide Transport Proteins
10
1997
51
1.110
Why?
Guanosine Triphosphate
3
2022
91
1.070
Why?
Kinetics
34
2014
1664
1.070
Why?
Binding Sites
29
2013
1301
1.030
Why?
Protein Structure, Secondary
16
2013
374
1.020
Why?
Macrophages
5
2020
1544
0.920
Why?
Guanosine Diphosphate
2
2021
20
0.890
Why?
Electron Spin Resonance Spectroscopy
8
2012
95
0.880
Why?
Multiprotein Complexes
3
2014
163
0.870
Why?
Receptors, Cell Surface
13
2007
382
0.870
Why?
Calcium Signaling
5
2014
249
0.860
Why?
Myristoylated Alanine-Rich C Kinase Substrate
3
2018
6
0.850
Why?
Calmodulin
4
2016
76
0.850
Why?
Protein Interaction Mapping
4
2010
109
0.840
Why?
Intracellular Signaling Peptides and Proteins
2
2016
455
0.820
Why?
Phosphatidylinositols
3
2022
57
0.790
Why?
Chemoreceptor Cells
7
2007
51
0.780
Why?
Models, Chemical
10
2013
263
0.740
Why?
Guanine Nucleotides
1
2021
14
0.740
Why?
Recombinant Proteins
13
2021
1350
0.730
Why?
Protein Engineering
19
2013
97
0.710
Why?
Cytosol
7
2007
226
0.710
Why?
Class III Phosphatidylinositol 3-Kinases
1
2020
2
0.700
Why?
rab5 GTP-Binding Proteins
1
2020
8
0.700
Why?
Pseudopodia
1
2020
26
0.660
Why?
Phosphatidylserines
6
2014
91
0.650
Why?
Spin Labels
5
2008
48
0.630
Why?
Endosomes
1
2020
136
0.630
Why?
Chromatography, High Pressure Liquid
1
2021
597
0.620
Why?
Amino Acid Substitution
11
2014
306
0.580
Why?
Receptors, Platelet-Derived Growth Factor
1
2017
15
0.570
Why?
Proto-Oncogene Proteins c-akt
2
2011
437
0.560
Why?
Conserved Sequence
3
2007
239
0.550
Why?
Enzyme Activation
9
2017
810
0.550
Why?
Cytoplasm
6
2005
272
0.540
Why?
Phosphatidylinositol 3-Kinase
1
2016
26
0.530
Why?
Biochemistry
2
2007
38
0.520
Why?
Carrier Proteins
9
1997
769
0.510
Why?
Dimerization
8
2013
198
0.510
Why?
Adaptor Proteins, Signal Transducing
3
2014
429
0.500
Why?
Fluorescence Resonance Energy Transfer
4
2013
177
0.500
Why?
Protein Interaction Domains and Motifs
3
2014
150
0.500
Why?
Anion Exchange Protein 1, Erythrocyte
8
1986
22
0.490
Why?
Protein Stability
2
2014
176
0.490
Why?
Biophysics
4
2024
69
0.490
Why?
Mutation
11
2021
3947
0.470
Why?
Microscopy, Fluorescence
6
2017
397
0.460
Why?
Cystine
1
2014
18
0.450
Why?
Spectrometry, Fluorescence
9
2010
168
0.450
Why?
Magnetic Resonance Spectroscopy
18
1996
610
0.440
Why?
Cell Movement
3
2020
968
0.430
Why?
Eukaryotic Cells
1
2014
39
0.430
Why?
3-Phosphoinositide-Dependent Protein Kinases
1
2013
1
0.420
Why?
Chlorides
9
1986
136
0.420
Why?
Amino Acid Sequence
12
2016
2138
0.420
Why?
Galactose
8
1997
33
0.390
Why?
Lipid Metabolism
2
2007
512
0.390
Why?
Thermotoga maritima
2
2013
12
0.380
Why?
Adaptation, Physiological
4
2020
549
0.370
Why?
Endosomal Sorting Complexes Required for Transport
1
2012
38
0.370
Why?
Diffusion
3
2023
116
0.370
Why?
Membrane Lipids
2
2010
90
0.370
Why?
Point Mutation
3
2009
235
0.350
Why?
Vesicular Transport Proteins
1
2012
84
0.350
Why?
Amino Acid Motifs
2
2009
225
0.350
Why?
Phosphorylation
7
2021
1758
0.340
Why?
Models, Theoretical
3
2005
574
0.340
Why?
Protein Structure, Quaternary
2
2013
125
0.330
Why?
RAW 264.7 Cells
2
2020
50
0.310
Why?
Bacterial Physiological Phenomena
3
2007
61
0.310
Why?
Peptide Fragments
5
2016
705
0.300
Why?
Isoenzymes
3
2008
304
0.290
Why?
Animals
19
2024
36836
0.290
Why?
Oncogenes
1
2008
116
0.290
Why?
Bacteria
3
2014
854
0.290
Why?
Static Electricity
6
2013
118
0.280
Why?
Tryptophan
5
2014
183
0.270
Why?
Humans
36
2024
136750
0.260
Why?
Membrane Microdomains
2
2003
31
0.260
Why?
Glycine
2
2005
175
0.250
Why?
Cell Line
5
2018
2838
0.240
Why?
Protein Domains
2
2017
289
0.240
Why?
Edetic Acid
2
2003
50
0.230
Why?
Single Molecule Imaging
1
2024
37
0.220
Why?
Cell Polarity
2
2020
141
0.220
Why?
Protein Kinase C beta
3
2014
21
0.210
Why?
Cations, Divalent
4
2010
52
0.210
Why?
Spin Trapping
1
2003
3
0.210
Why?
Hot Temperature
4
2021
390
0.200
Why?
Water
3
2004
457
0.200
Why?
Recombinant Fusion Proteins
4
2010
664
0.200
Why?
Surface Properties
5
2004
412
0.200
Why?
Plasmids
5
2007
360
0.200
Why?
Molecular Dynamics Simulation
4
2014
211
0.200
Why?
Electrophoresis, Polyacrylamide Gel
4
2009
345
0.200
Why?
Peptides
2
2000
981
0.190
Why?
Mice
8
2020
17758
0.190
Why?
Phosphatidylcholines
5
2007
147
0.190
Why?
Cyclophilin A
1
2002
26
0.190
Why?
Phosphotransferases
1
2001
24
0.190
Why?
Receptors, G-Protein-Coupled
1
2004
220
0.180
Why?
Chemotactic Factors
2
2007
56
0.180
Why?
Hydrolysis
1
2021
176
0.180
Why?
Fluorescent Dyes
4
2007
317
0.180
Why?
Spectrophotometry, Ultraviolet
1
2021
86
0.170
Why?
Aspartate Kinase
1
2000
1
0.170
Why?
Metals
3
1997
136
0.170
Why?
Molecular Sequence Data
6
2005
2894
0.170
Why?
Reproducibility of Results
3
2021
3264
0.170
Why?
Intracellular Membranes
1
2020
84
0.170
Why?
Diclofenac
1
2020
15
0.170
Why?
Time-Lapse Imaging
1
2020
21
0.170
Why?
Glutamic Acid
3
2011
246
0.170
Why?
Lymphocyte Antigen 96
2
2010
24
0.160
Why?
Chelating Agents
2
1997
75
0.160
Why?
Ibuprofen
1
2020
84
0.160
Why?
Endocytosis
1
2020
169
0.160
Why?
Troponin C
1
1998
5
0.150
Why?
Alanine
2
2013
151
0.150
Why?
Ultraviolet Rays
1
2021
390
0.150
Why?
Membranes, Artificial
1
1998
72
0.150
Why?
Oxidation-Reduction
3
2010
1059
0.150
Why?
Thermodynamics
6
2002
401
0.150
Why?
Crystallography, X-Ray
3
2013
476
0.140
Why?
Phospholipases A2
5
2006
80
0.140
Why?
Synaptotagmins
2
2012
21
0.140
Why?
Phosphopeptides
1
2017
20
0.140
Why?
Solvents
4
1999
108
0.140
Why?
Terbium
2
1996
4
0.140
Why?
Acetaminophen
1
2020
266
0.140
Why?
Biophysical Phenomena
3
2010
63
0.130
Why?
Sf9 Cells
1
2016
9
0.130
Why?
Aspirin
1
2020
387
0.130
Why?
Spodoptera
1
2016
40
0.130
Why?
Magnesium
3
1998
156
0.130
Why?
Leukocytes
1
2018
311
0.130
Why?
Structure-Activity Relationship
6
2013
570
0.130
Why?
Ligands
5
2010
661
0.130
Why?
Cloning, Molecular
5
1997
534
0.130
Why?
Fluorine Radioisotopes
1
1996
12
0.120
Why?
Cattle
2
2008
981
0.120
Why?
Erythrocyte Membrane
8
1986
55
0.120
Why?
Group IV Phospholipases A2
3
2006
47
0.120
Why?
Fluorine
5
1993
16
0.120
Why?
Osmolar Concentration
3
2009
171
0.120
Why?
Macromolecular Substances
3
2010
229
0.120
Why?
Glutathione Transferase
2
2007
105
0.110
Why?
Substrate Specificity
3
2008
371
0.110
Why?
Hydrophobic and Hydrophilic Interactions
2
2012
187
0.110
Why?
Protein Isoforms
2
2013
403
0.110
Why?
Protein Transport
2
2007
443
0.110
Why?
Microarray Analysis
1
2014
116
0.110
Why?
Bacteriorhodopsins
2
2005
11
0.110
Why?
Phospholipids
2
2013
222
0.110
Why?
Hydrogen-Ion Concentration
4
2009
560
0.110
Why?
Immunity, Innate
1
2020
825
0.110
Why?
Protein Folding
3
2002
280
0.110
Why?
Biological Transport, Active
7
1986
77
0.110
Why?
Models, Biological
6
2007
1773
0.110
Why?
Histidine
2
2007
64
0.110
Why?
Protein Denaturation
3
2002
74
0.110
Why?
Proteolysis
1
2014
177
0.110
Why?
Neoplasms
1
2008
2643
0.110
Why?
Phospholipases A2, Cytosolic
1
2013
7
0.100
Why?
Protein Multimerization
1
2014
191
0.100
Why?
Myocardium
1
1998
1001
0.100
Why?
Molecular Docking Simulation
1
2013
113
0.100
Why?
Mutagenesis
1
2013
179
0.100
Why?
Fibroblasts
1
2018
993
0.100
Why?
Trypsin
1
2012
77
0.100
Why?
Synaptotagmin I
1
2012
15
0.100
Why?
Multienzyme Complexes
1
2012
67
0.100
Why?
Nuclear Magnetic Resonance, Biomolecular
2
2007
340
0.100
Why?
Bacterial Outer Membrane Proteins
1
2012
58
0.100
Why?
Molecular Structure
4
1996
489
0.100
Why?
Computer Simulation
5
2013
973
0.100
Why?
Myosin-Light-Chain Kinase
1
2012
20
0.100
Why?
Transfection
2
2011
941
0.090
Why?
NIH 3T3 Cells
1
2011
144
0.090
Why?
Energy Transfer
2
2002
46
0.090
Why?
Fluoresceins
2
2003
47
0.090
Why?
Carbohydrate Metabolism
1
1991
59
0.090
Why?
In Vitro Techniques
3
2003
1089
0.090
Why?
Time Factors
2
2016
6808
0.090
Why?
Facilitated Diffusion
1
2010
3
0.090
Why?
Hydrodynamics
1
2010
41
0.090
Why?
Toll-Like Receptor 4
2
2010
273
0.090
Why?
Niflumic Acid
2
1986
3
0.080
Why?
Sequence Homology, Amino Acid
2
2004
385
0.080
Why?
Heterocyclic Compounds, 3-Ring
1
2010
32
0.080
Why?
Toll-Like Receptors
1
2010
185
0.080
Why?
Crystallization
2
2013
141
0.080
Why?
Photobleaching
1
2009
23
0.080
Why?
Methyltransferases
1
2009
78
0.080
Why?
Least-Squares Analysis
1
2009
79
0.080
Why?
Single-Cell Analysis
1
2011
311
0.070
Why?
3T3 Cells
1
2008
163
0.070
Why?
Cations
2
2002
84
0.070
Why?
Hydrogen Bonding
2
2014
163
0.070
Why?
Blood Proteins
2
2013
252
0.070
Why?
Ethylmaleimide
2
2003
18
0.070
Why?
Receptors, Neurotransmitter
1
1987
18
0.070
Why?
Phosphoproteins
2
2013
337
0.070
Why?
Sensory Receptor Cells
1
1988
98
0.070
Why?
Archaeal Proteins
1
2007
50
0.070
Why?
Cell Survival
2
2008
1116
0.070
Why?
Nicotinic Acids
1
1986
5
0.070
Why?
Oligonucleotide Probes
1
2007
51
0.070
Why?
Benzenesulfonates
1
1986
22
0.070
Why?
Feedback
1
2007
172
0.070
Why?
Oxadiazoles
1
1986
33
0.070
Why?
Taurine
1
1986
46
0.060
Why?
Lysine
1
2008
294
0.060
Why?
Methylation
2
1997
230
0.060
Why?
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
1
1985
10
0.060
Why?
Structural Homology, Protein
1
2005
27
0.060
Why?
Swine
1
2008
773
0.060
Why?
Calcium Channel Blockers
1
1986
167
0.060
Why?
Actins
1
2007
416
0.060
Why?
Organometallic Compounds
2
2000
111
0.060
Why?
Motion
2
1996
98
0.060
Why?
Sequence Homology
1
2004
40
0.060
Why?
Drug Delivery Systems
1
2008
362
0.060
Why?
Phosphatidylethanolamines
2
2002
77
0.060
Why?
Analgesics, Opioid
2
2010
991
0.060
Why?
Mathematics
4
1985
103
0.060
Why?
Halobacterium
1
1984
3
0.060
Why?
Dogs
1
2005
411
0.060
Why?
Periplasm
1
2004
12
0.050
Why?
Membrane Potentials
1
2005
283
0.050
Why?
Rhodopsin
1
2004
11
0.050
Why?
Carotenoids
1
1984
43
0.050
Why?
Computer Graphics
2
1996
42
0.050
Why?
Lipopolysaccharides
1
2007
886
0.050
Why?
Liposomes
2
2012
220
0.050
Why?
Rhodamines
1
2003
20
0.050
Why?
Cyclic N-Oxides
1
2003
29
0.050
Why?
Fluorescein
1
2003
25
0.050
Why?
Data Interpretation, Statistical
1
2004
363
0.050
Why?
Peptide Library
1
2003
88
0.050
Why?
Urea
1
2002
81
0.050
Why?
Glucose
3
1992
1019
0.050
Why?
Dansyl Compounds
1
2002
5
0.050
Why?
Sulfhydryl Compounds
2
1998
189
0.050
Why?
Peptide Hydrolases
1
2003
111
0.050
Why?
Catalysis
1
2002
307
0.040
Why?
Nitrogen
1
2002
168
0.040
Why?
Stilbenes
3
1985
35
0.040
Why?
Chlorine
3
1985
61
0.040
Why?
Proteins
1
2007
1009
0.040
Why?
Arginine
1
2002
271
0.040
Why?
Nitrilotriacetic Acid
1
2000
1
0.040
Why?
Lipids
1
2005
665
0.040
Why?
Benzoxazoles
1
1980
19
0.040
Why?
Chromatography, Affinity
1
2000
88
0.040
Why?
Indicators and Reagents
1
2000
106
0.040
Why?
Sequence Alignment
2
1998
342
0.040
Why?
Nickel
1
2000
62
0.040
Why?
Staining and Labeling
1
1980
148
0.040
Why?
Iodides
1
1998
8
0.040
Why?
Pyrimidinones
1
1980
113
0.040
Why?
Naphthalenesulfonates
1
1998
7
0.040
Why?
Fluorescence Polarization
1
1998
37
0.040
Why?
Isotopes
2
1991
33
0.040
Why?
Muscles
1
1980
325
0.040
Why?
Chickens
1
1998
191
0.040
Why?
Membrane Glycoproteins
1
2001
500
0.040
Why?
Pain Measurement
2
2010
521
0.030
Why?
Nerve Tissue Proteins
1
2001
595
0.030
Why?
Sequence Analysis
1
1996
36
0.030
Why?
Solubility
1
1997
245
0.030
Why?
Strontium
2
1998
14
0.030
Why?
Chemistry, Physical
1
1996
37
0.030
Why?
Chemical Phenomena
1
1996
83
0.030
Why?
Models, Structural
1
1995
40
0.030
Why?
Tetrahydrofolate Dehydrogenase
1
1996
23
0.030
Why?
L-Lactate Dehydrogenase
1
1996
121
0.030
Why?
Genetic Engineering
1
1996
91
0.030
Why?
Flagella
1
1995
20
0.030
Why?
Anions
2
1985
31
0.030
Why?
Genes, Bacterial
1
1995
164
0.030
Why?
p-Fluorophenylalanine
1
1994
2
0.030
Why?
Glutamates
1
1994
59
0.030
Why?
Electrons
1
2014
83
0.030
Why?
Cations, Monovalent
1
1993
6
0.030
Why?
Carboxylic Acids
1
1993
34
0.030
Why?
Movement
1
1995
272
0.030
Why?
Cryoelectron Microscopy
1
2014
189
0.030
Why?
Iodoacetamide
1
1992
5
0.020
Why?
Trehalose
1
2012
32
0.020
Why?
Organophosphates
1
1993
134
0.020
Why?
Gadolinium
1
1991
82
0.020
Why?
Molecular Conformation
1
1991
145
0.020
Why?
Rats
2
2010
5639
0.020
Why?
Lac Operon
1
1990
44
0.020
Why?
Infusion Pumps
1
2009
32
0.020
Why?
Myeloid Differentiation Factor 88
1
2010
99
0.020
Why?
Toll-Like Receptor 2
1
2010
115
0.020
Why?
Injections, Spinal
1
2009
105
0.020
Why?
Receptors, Opioid, mu
1
2009
74
0.020
Why?
Morphine
1
2010
158
0.020
Why?
Gene Expression Regulation, Bacterial
1
1991
324
0.020
Why?
Analgesia
1
2009
94
0.020
Why?
Hyperalgesia
1
2009
123
0.020
Why?
Naloxone
1
2009
121
0.020
Why?
Reaction Time
1
2009
412
0.020
Why?
Microglia
1
2010
251
0.020
Why?
Narcotic Antagonists
1
2009
179
0.020
Why?
Allosteric Regulation
1
1987
97
0.020
Why?
Species Specificity
1
1988
586
0.020
Why?
Substance Withdrawal Syndrome
1
2009
178
0.020
Why?
Mice, Inbred BALB C
1
2010
1269
0.020
Why?
Dinitrofluorobenzene
1
1986
6
0.020
Why?
Cyclohexanones
1
1986
9
0.020
Why?
Dipyridamole
1
1986
28
0.020
Why?
Cell Fractionation
1
1986
56
0.020
Why?
Phenylglyoxal
1
1985
1
0.020
Why?
Papain
1
1985
3
0.020
Why?
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid
1
1985
6
0.020
Why?
Interleukin-1
1
2010
964
0.020
Why?
Chymotrypsin
1
1985
22
0.020
Why?
Bromine
1
1985
5
0.020
Why?
Sonication
1
1985
13
0.020
Why?
Bicarbonates
1
1985
44
0.020
Why?
Promoter Regions, Genetic
1
1990
1249
0.010
Why?
Tumor Necrosis Factor-alpha
1
2010
1242
0.010
Why?
Biological Transport
1
1985
416
0.010
Why?
Cytoskeleton
1
1985
188
0.010
Why?
Halorhodopsins
1
1984
1
0.010
Why?
Bromides
1
1984
5
0.010
Why?
Muscle, Skeletal
1
1994
1707
0.010
Why?
Radioisotopes
1
1984
31
0.010
Why?
Binding, Competitive
1
1984
202
0.010
Why?
Cold Temperature
1
1985
178
0.010
Why?
Rats, Sprague-Dawley
1
2009
2486
0.010
Why?
Mice, Knockout
1
2010
3009
0.010
Why?
Cells, Cultured
1
2010
4192
0.010
Why?
Chick Embryo
1
1980
130
0.010
Why?
Cell Membrane Permeability
1
1980
78
0.010
Why?
Barium
1
1998
26
0.010
Why?
CHO Cells
1
1998
161
0.010
Why?
COS Cells
1
1998
188
0.010
Why?
Cricetinae
1
1998
289
0.010
Why?
Blood Glucose
1
1986
2181
0.010
Why?
Male
2
2010
67305
0.010
Why?
Cytochalasin B
1
1986
17
0.000
Why?
Falke's Networks
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