 Chymotrypsin
"Chymotrypsin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.
| Descriptor ID |
D002918
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| MeSH Number(s) |
D08.811.277.656.300.760.176 D08.811.277.656.959.350.176
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chymotrypsin".
Below are MeSH descriptors whose meaning is more specific than "Chymotrypsin".
This graph shows the total number of publications written about "Chymotrypsin" by people in this website by year, and whether "Chymotrypsin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 0 | 2 | 2 | | 2003 | 1 | 1 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 2 | 0 | 2 | | 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Chymotrypsin" by people in Profiles.
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Borovsky D, Roug? P. Heliothis virescens chymotrypsin is translationally controlled by AeaTMOF binding ABC putative receptor. Arch Insect Biochem Physiol. 2023 Oct; 114(2):1-24.
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Borovsky D, Roug? P. Cloning and characterization of Aedes aegypti blood downregulated chymotrypsin II. Arch Insect Biochem Physiol. 2023 Jul; 113(3):e22018.
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Munasinghe A, Baker SL, Lin P, Russell AJ, Colina CM. Structure-function-dynamics of a-chymotrypsin based conjugates as a function of polymer charge. Soft Matter. 2020 Jan 02; 16(2):456-465.
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Baker SL, Munasinghe A, Murata H, Lin P, Matyjaszewski K, Colina CM, Russell AJ. Intramolecular Interactions of Conjugated Polymers Mimic Molecular Chaperones to Stabilize Protein-Polymer Conjugates. Biomacromolecules. 2018 09 10; 19(9):3798-3813.
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Carmali S, Murata H, Cummings C, Matyjaszewski K, Russell AJ. Polymer-Based Protein Engineering: Synthesis and Characterization of Armored, High Graft Density Polymer-Protein Conjugates. Methods Enzymol. 2017; 590:347-380.
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Cummings CS, Campbell AS, Baker SL, Carmali S, Murata H, Russell AJ. Design of Stomach Acid-Stable and Mucin-Binding Enzyme Polymer Conjugates. Biomacromolecules. 2017 02 13; 18(2):576-586.
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Murata H, Cummings CS, Koepsel RR, Russell AJ. Rational tailoring of substrate and inhibitor affinity via ATRP polymer-based protein engineering. Biomacromolecules. 2014 Jul 14; 15(7):2817-23.
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Cummings C, Murata H, Koepsel R, Russell AJ. Dramatically increased pH and temperature stability of chymotrypsin using dual block polymer-based protein engineering. Biomacromolecules. 2014 Mar 10; 15(3):763-71.
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Nordwald EM, Kaar JL. Mediating electrostatic binding of 1-butyl-3-methylimidazolium chloride to enzyme surfaces improves conformational stability. J Phys Chem B. 2013 Aug 01; 117(30):8977-86.
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Cummings C, Murata H, Koepsel R, Russell AJ. Tailoring enzyme activity and stability using polymer-based protein engineering. Biomaterials. 2013 Oct; 34(30):7437-43.
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