Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Connection

Joseph Falke to Humans

This is a "connection" page, showing publications Joseph Falke has written about Humans.

 
Connection Strength
 
 
 
0.278
 
  1. Swisher GH, Hannan JP, Cordaro NJ, Erbse AH, Falke JJ. Ras-guanine nucleotide complexes: A UV spectral deconvolution method to analyze protein concentration, nucleotide stoichiometry, and purity. Anal Biochem. 2021 04 01; 618:114066.
    View in: PubMed
    Score: 0.021
  2. Buckles TC, Ohashi Y, Tremel S, McLaughlin SH, Pardon E, Steyaert J, Gordon MT, Williams RL, Falke JJ. The G-Protein Rab5A Activates VPS34 Complex II, a Class III PI3K, by a Dual Regulatory Mechanism. Biophys J. 2020 12 01; 119(11):2205-2218.
    View in: PubMed
    Score: 0.020
  3. Buckles TC, Ziemba BP, Djukovic D, Falke JJ. Rapid exposure of macrophages to drugs resolves four classes of effects on the leading edge sensory pseudopod: Non-perturbing, adaptive, disruptive, and activating. PLoS One. 2020; 15(5):e0233012.
    View in: PubMed
    Score: 0.020
  4. Ziemba BP, Swisher GH, Masson G, Burke JE, Williams RL, Falke JJ. Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module. Biochemistry. 2016 Nov 22; 55(46):6395-6405.
    View in: PubMed
    Score: 0.015
  5. Ziemba BP, Burke JE, Masson G, Williams RL, Falke JJ. Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway. Biophys J. 2016 04 26; 110(8):1811-1825.
    View in: PubMed
    Score: 0.015
  6. Ziemba BP, Li J, Landgraf KE, Knight JD, Voth GA, Falke JJ. Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-a. Biochemistry. 2014 Mar 18; 53(10):1697-713.
    View in: PubMed
    Score: 0.013
  7. Falke JJ, Ziemba BP. Interplay between phosphoinositide lipids and calcium signals at the leading edge of chemotaxing ameboid cells. Chem Phys Lipids. 2014 Sep; 182:73-9.
    View in: PubMed
    Score: 0.013
  8. Ziemba BP, Pilling C, Calleja V, Larijani B, Falke JJ. The PH domain of phosphoinositide-dependent kinase-1 exhibits a novel, phospho-regulated monomer-dimer equilibrium with important implications for kinase domain activation: single-molecule and ensemble studies. Biochemistry. 2013 Jul 16; 52(28):4820-9.
    View in: PubMed
    Score: 0.012
  9. Ziemba BP, Falke JJ. Lateral diffusion of peripheral membrane proteins on supported lipid bilayers is controlled by the additive frictional drags of (1) bound lipids and (2) protein domains penetrating into the bilayer hydrocarbon core. Chem Phys Lipids. 2013 Jul-Aug; 172-173:67-77.
    View in: PubMed
    Score: 0.012
  10. Chen HC, Ziemba BP, Landgraf KE, Corbin JA, Falke JJ. Membrane docking geometry of GRP1 PH domain bound to a target lipid bilayer: an EPR site-directed spin-labeling and relaxation study. PLoS One. 2012; 7(3):e33640.
    View in: PubMed
    Score: 0.011
  11. Ziemba BP, Knight JD, Falke JJ. Assembly of membrane-bound protein complexes: detection and analysis by single molecule diffusion. Biochemistry. 2012 Feb 28; 51(8):1638-47.
    View in: PubMed
    Score: 0.011
  12. Falke JJ. Lipid targeting domain with dual-membrane specificity that expands the diversity of intracellular targeting reactions. Proc Natl Acad Sci U S A. 2012 Feb 07; 109(6):1816-7.
    View in: PubMed
    Score: 0.011
  13. Pilling C, Landgraf KE, Falke JJ. The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3). Biochemistry. 2011 Nov 15; 50(45):9845-56.
    View in: PubMed
    Score: 0.011
  14. Knight JD, Falke JJ. Single-molecule fluorescence studies of a PH domain: new insights into the membrane docking reaction. Biophys J. 2009 Jan; 96(2):566-82.
    View in: PubMed
    Score: 0.009
  15. Landgraf KE, Pilling C, Falke JJ. Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain. Biochemistry. 2008 Nov 25; 47(47):12260-9.
    View in: PubMed
    Score: 0.009
  16. Landgraf KE, Malmberg NJ, Falke JJ. Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study. Biochemistry. 2008 Aug 12; 47(32):8301-16.
    View in: PubMed
    Score: 0.009
  17. Evans JH, Murray D, Leslie CC, Falke JJ. Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain. Mol Biol Cell. 2006 Jan; 17(1):56-66.
    View in: PubMed
    Score: 0.007
  18. Malmberg NJ, Falke JJ. Use of EPR power saturation to analyze the membrane-docking geometries of peripheral proteins: applications to C2 domains. Annu Rev Biophys Biomol Struct. 2005; 34:71-90.
    View in: PubMed
    Score: 0.007
  19. Corbin JA, Dirkx RA, Falke JJ. GRP1 pleckstrin homology domain: activation parameters and novel search mechanism for rare target lipid. Biochemistry. 2004 Dec 28; 43(51):16161-73.
    View in: PubMed
    Score: 0.007
  20. Malmberg NJ, Varma S, Jakobsson E, Falke JJ. Ca2+ activation of the cPLA2 C2 domain: ordered binding of two Ca2+ ions with positive cooperativity. Biochemistry. 2004 Dec 28; 43(51):16320-8.
    View in: PubMed
    Score: 0.007
  21. Miller AF, Falke JJ. Chemotaxis receptors and signaling. Adv Protein Chem. 2004; 68:393-444.
    View in: PubMed
    Score: 0.006
  22. Malmberg NJ, Van Buskirk DR, Falke JJ. Membrane-docking loops of the cPLA2 C2 domain: detailed structural analysis of the protein-membrane interface via site-directed spin-labeling. Biochemistry. 2003 Nov 18; 42(45):13227-40.
    View in: PubMed
    Score: 0.006
  23. Nalefski EA, Slazas MM, Falke JJ. Ca2+-signaling cycle of a membrane-docking C2 domain. Biochemistry. 1997 Oct 07; 36(40):12011-8.
    View in: PubMed
    Score: 0.004
  24. Li J, Ziemba BP, Falke JJ, Voth GA. Interactions of protein kinase C-a C1A and C1B domains with membranes: a combined computational and experimental study. J Am Chem Soc. 2014 Aug 20; 136(33):11757-66.
    View in: PubMed
    Score: 0.003
  25. Brandt DS, Coffman MD, Falke JJ, Knight JD. Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: mechanistic contrast between isoforms 1 and 7. Biochemistry. 2012 Oct 02; 51(39):7654-64.
    View in: PubMed
    Score: 0.003
  26. Hutchinson MR, Loram LC, Zhang Y, Shridhar M, Rezvani N, Berkelhammer D, Phipps S, Foster PS, Landgraf K, Falke JJ, Rice KC, Maier SF, Yin H, Watkins LR. Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity. Neuroscience. 2010 Jun 30; 168(2):551-63.
    View in: PubMed
    Score: 0.002
  27. Falke JJ, Chan SI. Molecular mechanisms of band 3 inhibitors. 1. Transport site inhibitors. Biochemistry. 1986 Dec 02; 25(24):7888-94.
    View in: PubMed
    Score: 0.002
  28. Falke JJ, Chan SI. Molecular mechanisms of band 3 inhibitors. 2. Channel blockers. Biochemistry. 1986 Dec 02; 25(24):7895-8.
    View in: PubMed
    Score: 0.002
  29. Falke JJ, Chan SI. Molecular mechanisms of band 3 inhibitors. 3. Translocation inhibitors. Biochemistry. 1986 Dec 02; 25(24):7899-906.
    View in: PubMed
    Score: 0.002
  30. Falke JJ, Kanes KJ, Chan SI. The minimal structure containing the band 3 anion transport site. A 35Cl NMR study. J Biol Chem. 1985 Oct 25; 260(24):13294-303.
    View in: PubMed
    Score: 0.002
  31. Falke JJ, Chan SI. Evidence that anion transport by band 3 proceeds via a ping-pong mechanism involving a single transport site. A 35 Cl NMR study. J Biol Chem. 1985 Aug 15; 260(17):9537-44.
    View in: PubMed
    Score: 0.002
  32. Falke JJ, Kanes KJ, Chan SI. The kinetic equation for the chloride transport cycle of band 3. A 35Cl and 37Cl NMR study. J Biol Chem. 1985 Aug 15; 260(17):9545-51.
    View in: PubMed
    Score: 0.002
  33. Falke JJ, Pace RJ, Chan SI. Chloride binding to the anion transport binding sites of band 3. A 35Cl NMR study. J Biol Chem. 1984 May 25; 259(10):6472-80.
    View in: PubMed
    Score: 0.002
  34. Falke JJ, Pace RJ, Chan SI. Direct observation of the transmembrane recruitment of band 3 transport sites by competitive inhibitors. A 35Cl NMR study. J Biol Chem. 1984 May 25; 259(10):6481-91.
    View in: PubMed
    Score: 0.002
  35. Wang JF, Falke JJ, Chan SI. A proton NMR study of the mechanism of the erythrocyte glucose transporter. Proc Natl Acad Sci U S A. 1986 May; 83(10):3277-81.
    View in: PubMed
    Score: 0.000
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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