 Connection
Joseph Falke to Calcium
This is a "connection" page, showing publications Joseph Falke has written about Calcium.
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Connection Strength |
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2.632 |
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Ziemba BP, Falke JJ. A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages. PLoS One. 2018; 13(5):e0196678.
Score: 0.409
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Corbin JA, Evans JH, Landgraf KE, Falke JJ. Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity. Biochemistry. 2007 Apr 10; 46(14):4322-36.
Score: 0.189
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Evans JH, Murray D, Leslie CC, Falke JJ. Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain. Mol Biol Cell. 2006 Jan; 17(1):56-66.
Score: 0.172
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Malmberg NJ, Falke JJ. Use of EPR power saturation to analyze the membrane-docking geometries of peripheral proteins: applications to C2 domains. Annu Rev Biophys Biomol Struct. 2005; 34:71-90.
Score: 0.162
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Malmberg NJ, Varma S, Jakobsson E, Falke JJ. Ca2+ activation of the cPLA2 C2 domain: ordered binding of two Ca2+ ions with positive cooperativity. Biochemistry. 2004 Dec 28; 43(51):16320-8.
Score: 0.162
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Kohout SC, Corbal?n-Garc?a S, Torrecillas A, Gom?z-Fernand?z JC, Falke JJ. C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state. Biochemistry. 2002 Sep 24; 41(38):11411-24.
Score: 0.139
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Nalefski EA, Falke JJ. Location of the membrane-docking face on the Ca2+-activated C2 domain of cytosolic phospholipase A2. Biochemistry. 1998 Dec 22; 37(51):17642-50.
Score: 0.107
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Hazard AL, Kohout SC, Stricker NL, Putkey JA, Falke JJ. The kinetic cycle of cardiac troponin C: calcium binding and dissociation at site II trigger slow conformational rearrangements. Protein Sci. 1998 Nov; 7(11):2451-9.
Score: 0.106
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Nalefski EA, Slazas MM, Falke JJ. Ca2+-signaling cycle of a membrane-docking C2 domain. Biochemistry. 1997 Oct 07; 36(40):12011-8.
Score: 0.098
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Drake SK, Zimmer MA, Miller CL, Falke JJ. Optimizing the metal binding parameters of an EF-hand-like calcium chelation loop: coordinating side chains play a more important tuning role than chelation loop flexibility. Biochemistry. 1997 Aug 12; 36(32):9917-26.
Score: 0.097
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Peersen OB, Madsen TS, Falke JJ. Intermolecular tuning of calmodulin by target peptides and proteins: differential effects on Ca2+ binding and implications for kinase activation. Protein Sci. 1997 Apr; 6(4):794-807.
Score: 0.095
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Ziemba BP, Swisher GH, Masson G, Burke JE, Williams RL, Falke JJ. Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module. Biochemistry. 2016 Nov 22; 55(46):6395-6405.
Score: 0.092
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Drake SK, Lee KL, Falke JJ. Tuning the equilibrium ion affinity and selectivity of the EF-hand calcium binding motif: substitutions at the gateway position. Biochemistry. 1996 May 28; 35(21):6697-705.
Score: 0.089
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Ziemba BP, Burke JE, Masson G, Williams RL, Falke JJ. Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway. Biophys J. 2016 04 26; 110(8):1811-1825.
Score: 0.089
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Falke JJ, Drake SK, Hazard AL, Peersen OB. Molecular tuning of ion binding to calcium signaling proteins. Q Rev Biophys. 1994 Aug; 27(3):219-90.
Score: 0.079
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Renner M, Danielson MA, Falke JJ. Kinetic control of Ca(II) signaling: tuning the ion dissociation rates of EF-hand Ca(II) binding sites. Proc Natl Acad Sci U S A. 1993 Jul 15; 90(14):6493-7.
Score: 0.073
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Brandt DS, Coffman MD, Falke JJ, Knight JD. Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: mechanistic contrast between isoforms 1 and 7. Biochemistry. 2012 Oct 02; 51(39):7654-64.
Score: 0.069
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Ziemba BP, Knight JD, Falke JJ. Assembly of membrane-bound protein complexes: detection and analysis by single molecule diffusion. Biochemistry. 2012 Feb 28; 51(8):1638-47.
Score: 0.066
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Falke JJ, Snyder EE, Thatcher KC, Voertler CS. Quantitating and engineering the ion specificity of an EF-hand-like Ca2+ binding. Biochemistry. 1991 Sep 03; 30(35):8690-7.
Score: 0.064
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Luck LA, Falke JJ. 19F NMR studies of the D-galactose chemosensory receptor. 2. Ca(II) binding yields a local structural change. Biochemistry. 1991 Apr 30; 30(17):4257-61.
Score: 0.063
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Lai CL, Landgraf KE, Voth GA, Falke JJ. Membrane docking geometry and target lipid stoichiometry of membrane-bound PKCa C2 domain: a combined molecular dynamics and experimental study. J Mol Biol. 2010 Sep 17; 402(2):301-10.
Score: 0.060
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Snyder EE, Buoscio BW, Falke JJ. Calcium(II) site specificity: effect of size and charge on metal ion binding to an EF-hand-like site. Biochemistry. 1990 Apr 24; 29(16):3937-43.
Score: 0.059
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Kohout SC, Corbal?n-Garc?a S, G?mez-Fern?ndez JC, Falke JJ. C2 domain of protein kinase C alpha: elucidation of the membrane docking surface by site-directed fluorescence and spin labeling. Biochemistry. 2003 Feb 11; 42(5):1254-65.
Score: 0.036
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Nalefski EA, Wisner MA, Chen JZ, Sprang SR, Fukuda M, Mikoshiba K, Falke JJ. C2 domains from different Ca2+ signaling pathways display functional and mechanistic diversity. Biochemistry. 2001 Mar 13; 40(10):3089-100.
Score: 0.031
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Nalefski EA, McDonagh T, Somers W, Seehra J, Falke JJ, Clark JD. Independent folding and ligand specificity of the C2 calcium-dependent lipid binding domain of cytosolic phospholipase A2. J Biol Chem. 1998 Jan 16; 273(3):1365-72.
Score: 0.025
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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