 Protein Multimerization
"Protein Multimerization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The assembly of the QUATERNARY PROTEIN STRUCTURE of multimeric proteins (MULTIPROTEIN COMPLEXES) from their composite PROTEIN SUBUNITS.
| Descriptor ID |
D055503
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| MeSH Number(s) |
G02.111.694
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| Concept/Terms |
Protein Multimerization- Protein Multimerization
- Multimerization, Protein
- Protein Multimer Assembly
- Assembly, Protein Multimer
- Multimer Assembly, Protein
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Below are MeSH descriptors whose meaning is more general than "Protein Multimerization".
Below are MeSH descriptors whose meaning is more specific than "Protein Multimerization".
This graph shows the total number of publications written about "Protein Multimerization" by people in this website by year, and whether "Protein Multimerization" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 4 | 5 | | 2010 | 1 | 9 | 10 | | 2011 | 3 | 8 | 11 | | 2012 | 3 | 9 | 12 | | 2013 | 2 | 13 | 15 | | 2014 | 5 | 14 | 19 | | 2015 | 3 | 9 | 12 | | 2016 | 5 | 5 | 10 | | 2017 | 2 | 10 | 12 | | 2018 | 2 | 7 | 9 | | 2019 | 2 | 6 | 8 | | 2020 | 1 | 7 | 8 | | 2021 | 2 | 2 | 4 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 | | 2024 | 0 | 4 | 4 | | 2025 | 3 | 6 | 9 | | 2026 | 0 | 2 | 2 |
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Below are the most recent publications written about "Protein Multimerization" by people in Profiles.
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Gaurav N, Qin W, Selvam K, Zhou Z, Liu J, Yin Y, Singh RK, O'Hara RA, Tavaf Z, Kumar A, Kono H, Narlikar GJ, Banaszynski LA, Leonhardt H, Kutateladze TG. HP1? self-assembles and cooperates with KAP1 in repression of long noncoding RNA AI662270 in ESCs. Cell Rep. 2026 Feb 24; 45(2):116874.
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Lee E, Redzic JS, Gordon B, Saviola AJ, Tran N, Maroney SP, Ashby NL, Shaw S, Fulte S, McCarty A, Holyoak T, Meyer N, Hansen KC, Clark SE, Eisenmesser E. Streptococcus pneumoniae HtrA is a dynamic and monomeric virulence factor capable of forming larger oligomeric complexes. Protein Sci. 2026 Jan; 35(1):e70411.
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Jing T, Shan Z, Dinh T, Biswas A, Jang S, Greenwood J, Li M, Zhang Z, Gray G, Shin HJ, Zhou B, Passos D, Strutzenberg TS, Aiyer S, Andrade L, Zhang Y, Li Z, Craigie R, Engelman AN, Kvaratskhelia M, Lyumkis D. Oligomeric HIV-1 integrase structures reveal functional plasticity for intasome assembly and RNA binding. Nat Commun. 2025 Oct 24; 16(1):9430.
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Wu J, Wan C, Tian Y, Ouyang Y, Puscher H, Li S, Yin Q, Shen J. Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanism. Sci Adv. 2025 Sep 12; 11(37):eadw9158.
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Zorc SA, Munoz-Tello P, O'Leary T, Yu X, Karadi Giridhar MN, Hondros AD, Hansel-Harris A, Forli S, Griffin PR, Kojetin DJ, Roy RN, Janiszewska M. Structural insights into IMP2 dimerization and RNA binding. J Struct Biol. 2025 Dec; 217(4):108247.
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Kumar A, Sakuraba S, Gaurav N, Selvam K, Kutateladze TG, Kono H. Mechanistic Insights into HP1a CSD Oligomerization and the Role of PxVxL Motif-Containing Proteins. J Chem Inf Model. 2025 Aug 25; 65(16):8768-8780.
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Parks KR, Moodie Z, Allen MA, Yen C, Furch BD, MacPhee KJ, Ozorowski G, Heptinstall J, Hahn WO, Zheng Z, Lu H, Grant S, Domin E, Duff MO, Seese A, Marini-Macouzet C, Ballweber-Fleming L, Lee WH, Cottrell CA, Liguori A, Georgeson E, Alavi N, Kubitz M, Phelps N, Seaton KE, Cohen KW, Anderson MA, Mondal K, Laufer DS, Kublin JG, Ward AB, Hyrien O, De Rosa SC, Himansu S, Leav B, Reuter C, Tomaras GD, Montefiori D, Walsh SR, Frank I, Sobieszczyk ME, Goepfert PA, Stephenson KE, Baden LR, Van Tieu H, Keefer MC, Clark J, Riddler SA, Schief WR, McElrath MJ. Vaccination with mRNA-encoded membrane-anchored HIV envelope trimers elicited tier 2 neutralizing antibodies in a phase 1 clinical trial. Sci Transl Med. 2025 Jul 30; 17(809):eady6831.
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Campaña MB, Perkins MR, McCabe MC, Neumann A, Larson ED, Fantauzzo KA. PDGFRa/ß heterodimer activation negatively affects downstream ERK1/2 signaling and cellular proliferation. Nat Commun. 2025 May 22; 16(1):4754.
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Sun X, Yegambaram M, Lu Q, Garcia Flores AE, Pokharel MD, Soto J, Aggarwal S, Wang T, Fineman JR, Black SM. Mitochondrial fission produces a Warburg effect via the oxidative inhibition of prolyl hydroxylase domain-2. Redox Biol. 2025 04; 81:103529.
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Singh A, Jangid K, Nehul S, Dhaka P, Rani R, Pareek A, Sharma GK, Kumar P, Tomar S. Structural and Mechanistic Insights into the Main Protease (Mpro) Dimer Interface Destabilization Inhibitor: Unveiling New Therapeutic Avenues against SARS-CoV-2. Biochemistry. 2025 04 01; 64(7):1589-1605.
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