Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

Joseph Falke to Cell Membrane

This is a "connection" page, showing publications Joseph Falke has written about Cell Membrane.

 
Connection Strength
 
 
 
2.999
 
  1. Ziemba BP, Swisher GH, Masson G, Burke JE, Williams RL, Falke JJ. Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module. Biochemistry. 2016 Nov 22; 55(46):6395-6405.
    View in: PubMed
    Score: 0.442
  2. Ziemba BP, Li J, Landgraf KE, Knight JD, Voth GA, Falke JJ. Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-a. Biochemistry. 2014 Mar 18; 53(10):1697-713.
    View in: PubMed
    Score: 0.367
  3. Chen HC, Ziemba BP, Landgraf KE, Corbin JA, Falke JJ. Membrane docking geometry of GRP1 PH domain bound to a target lipid bilayer: an EPR site-directed spin-labeling and relaxation study. PLoS One. 2012; 7(3):e33640.
    View in: PubMed
    Score: 0.321
  4. Knight JD, Falke JJ. Single-molecule fluorescence studies of a PH domain: new insights into the membrane docking reaction. Biophys J. 2009 Jan; 96(2):566-82.
    View in: PubMed
    Score: 0.256
  5. Landgraf KE, Pilling C, Falke JJ. Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain. Biochemistry. 2008 Nov 25; 47(47):12260-9.
    View in: PubMed
    Score: 0.255
  6. Corbin JA, Evans JH, Landgraf KE, Falke JJ. Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity. Biochemistry. 2007 Apr 10; 46(14):4322-36.
    View in: PubMed
    Score: 0.226
  7. Evans JH, Murray D, Leslie CC, Falke JJ. Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain. Mol Biol Cell. 2006 Jan; 17(1):56-66.
    View in: PubMed
    Score: 0.205
  8. Gordon MT, Ziemba BP, Falke JJ. Single-molecule studies reveal regulatory interactions between master kinases PDK1, AKT1, and PKC. Biophys J. 2021 12 21; 120(24):5657-5673.
    View in: PubMed
    Score: 0.156
  9. Ziemba BP, Falke JJ. A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages. PLoS One. 2018; 13(5):e0196678.
    View in: PubMed
    Score: 0.122
  10. Ziemba BP, Burke JE, Masson G, Williams RL, Falke JJ. Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway. Biophys J. 2016 04 26; 110(8):1811-1825.
    View in: PubMed
    Score: 0.106
  11. Chervitz SA, Lin CM, Falke JJ. Transmembrane signaling by the aspartate receptor: engineered disulfides reveal static regions of the subunit interface. Biochemistry. 1995 Aug 01; 34(30):9722-33.
    View in: PubMed
    Score: 0.101
  12. Pilling C, Landgraf KE, Falke JJ. The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3). Biochemistry. 2011 Nov 15; 50(45):9845-56.
    View in: PubMed
    Score: 0.078
  13. Jaud S, Tobias DJ, Falke JJ, White SH. Self-induced docking site of a deeply embedded peripheral membrane protein. Biophys J. 2007 Jan 15; 92(2):517-24.
    View in: PubMed
    Score: 0.055
  14. Malmberg NJ, Falke JJ. Use of EPR power saturation to analyze the membrane-docking geometries of peripheral proteins: applications to C2 domains. Annu Rev Biophys Biomol Struct. 2005; 34:71-90.
    View in: PubMed
    Score: 0.049
  15. Miller AS, Falke JJ. Side chains at the membrane-water interface modulate the signaling state of a transmembrane receptor. Biochemistry. 2004 Feb 24; 43(7):1763-70.
    View in: PubMed
    Score: 0.046
  16. Kohout SC, Corbal?n-Garc?a S, Torrecillas A, Gom?z-Fernand?z JC, Falke JJ. C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state. Biochemistry. 2002 Sep 24; 41(38):11411-24.
    View in: PubMed
    Score: 0.041
  17. Falke JJ, Hazelbauer GL. Transmembrane signaling in bacterial chemoreceptors. Trends Biochem Sci. 2001 Apr; 26(4):257-65.
    View in: PubMed
    Score: 0.037
  18. Nalefski EA, Slazas MM, Falke JJ. Ca2+-signaling cycle of a membrane-docking C2 domain. Biochemistry. 1997 Oct 07; 36(40):12011-8.
    View in: PubMed
    Score: 0.029
  19. Chervitz SA, Falke JJ. Lock on/off disulfides identify the transmembrane signaling helix of the aspartate receptor. J Biol Chem. 1995 Oct 13; 270(41):24043-53.
    View in: PubMed
    Score: 0.026
  20. Danielson MA, Biemann HP, Koshland DE, Falke JJ. Attractant- and disulfide-induced conformational changes in the ligand binding domain of the chemotaxis aspartate receptor: a 19F NMR study. Biochemistry. 1994 May 24; 33(20):6100-9.
    View in: PubMed
    Score: 0.023
  21. Lai CL, Srivastava A, Pilling C, Chase AR, Falke JJ, Voth GA. Molecular mechanism of membrane binding of the GRP1 PH domain. J Mol Biol. 2013 Sep 09; 425(17):3073-90.
    View in: PubMed
    Score: 0.022
  22. Falke JJ, Dernburg AF, Sternberg DA, Zalkin N, Milligan DL, Koshland DE. Structure of a bacterial sensory receptor. A site-directed sulfhydryl study. J Biol Chem. 1988 Oct 15; 263(29):14850-8.
    View in: PubMed
    Score: 0.016
  23. Frazier AA, Wisner MA, Malmberg NJ, Victor KG, Fanucci GE, Nalefski EA, Falke JJ, Cafiso DS. Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling. Biochemistry. 2002 May 21; 41(20):6282-92.
    View in: PubMed
    Score: 0.010
  24. Falke J, Lazarides E. Staining of viable and nonviable myotubes and of myofibrils by the fluorescent dye merocyanine 540. Differentiation. 1980; 17(3):199-204.
    View in: PubMed
    Score: 0.009
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2024 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)