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Connection

Joseph Falke to Binding Sites

This is a "connection" page, showing publications Joseph Falke has written about Binding Sites.

 
Connection Strength
 
 
 
1.103
 
  1. Miller AS, Kohout SC, Gilman KA, Falke JJ. CheA Kinase of bacterial chemotaxis: chemical mapping of four essential docking sites. Biochemistry. 2006 Jul 25; 45(29):8699-711.
    View in: PubMed
    Score: 0.224
  2. Ziemba BP, Knight JD, Falke JJ. Assembly of membrane-bound protein complexes: detection and analysis by single molecule diffusion. Biochemistry. 2012 Feb 28; 51(8):1638-47.
    View in: PubMed
    Score: 0.082
  3. Pilling C, Landgraf KE, Falke JJ. The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3). Biochemistry. 2011 Nov 15; 50(45):9845-56.
    View in: PubMed
    Score: 0.081
  4. Bass RB, Miller AS, Gloor SL, Falke JJ. The PICM chemical scanning method for identifying domain-domain and protein-protein interfaces: applications to the core signaling complex of E. coli chemotaxis. Methods Enzymol. 2007; 423:3-24.
    View in: PubMed
    Score: 0.058
  5. Malmberg NJ, Varma S, Jakobsson E, Falke JJ. Ca2+ activation of the cPLA2 C2 domain: ordered binding of two Ca2+ ions with positive cooperativity. Biochemistry. 2004 Dec 28; 43(51):16320-8.
    View in: PubMed
    Score: 0.050
  6. Bornhorst JA, Falke JJ. Quantitative analysis of aspartate receptor signaling complex reveals that the homogeneous two-state model is inadequate: development of a heterogeneous two-state model. J Mol Biol. 2003 Mar 07; 326(5):1597-614.
    View in: PubMed
    Score: 0.044
  7. Kohout SC, Corbal?n-Garc?a S, Torrecillas A, Gom?z-Fernand?z JC, Falke JJ. C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state. Biochemistry. 2002 Sep 24; 41(38):11411-24.
    View in: PubMed
    Score: 0.043
  8. Falke JJ. Enzymology. A moving story. Science. 2002 Feb 22; 295(5559):1480-1.
    View in: PubMed
    Score: 0.041
  9. Bornhorst JA, Falke JJ. Evidence that both ligand binding and covalent adaptation drive a two-state equilibrium in the aspartate receptor signaling complex. J Gen Physiol. 2001 Dec; 118(6):693-710.
    View in: PubMed
    Score: 0.041
  10. Nalefski EA, Wisner MA, Chen JZ, Sprang SR, Fukuda M, Mikoshiba K, Falke JJ. C2 domains from different Ca2+ signaling pathways display functional and mechanistic diversity. Biochemistry. 2001 Mar 13; 40(10):3089-100.
    View in: PubMed
    Score: 0.039
  11. Trammell MA, Falke JJ. Identification of a site critical for kinase regulation on the central processing unit (CPU) helix of the aspartate receptor. Biochemistry. 1999 Jan 05; 38(1):329-36.
    View in: PubMed
    Score: 0.033
  12. Nalefski EA, Falke JJ. Location of the membrane-docking face on the Ca2+-activated C2 domain of cytosolic phospholipase A2. Biochemistry. 1998 Dec 22; 37(51):17642-50.
    View in: PubMed
    Score: 0.033
  13. Hazard AL, Kohout SC, Stricker NL, Putkey JA, Falke JJ. The kinetic cycle of cardiac troponin C: calcium binding and dissociation at site II trigger slow conformational rearrangements. Protein Sci. 1998 Nov; 7(11):2451-9.
    View in: PubMed
    Score: 0.033
  14. Nalefski EA, Slazas MM, Falke JJ. Ca2+-signaling cycle of a membrane-docking C2 domain. Biochemistry. 1997 Oct 07; 36(40):12011-8.
    View in: PubMed
    Score: 0.030
  15. Drake SK, Lee KL, Falke JJ. Tuning the equilibrium ion affinity and selectivity of the EF-hand calcium binding motif: substitutions at the gateway position. Biochemistry. 1996 May 28; 35(21):6697-705.
    View in: PubMed
    Score: 0.028
  16. Drake SK, Falke JJ. Kinetic tuning of the EF-hand calcium binding motif: the gateway residue independently adjusts (i) barrier height and (ii) equilibrium. Biochemistry. 1996 Feb 13; 35(6):1753-60.
    View in: PubMed
    Score: 0.027
  17. Careaga CL, Sutherland J, Sabeti J, Falke JJ. Large amplitude twisting motions of an interdomain hinge: a disulfide trapping study of the galactose-glucose binding protein. Biochemistry. 1995 Mar 07; 34(9):3048-55.
    View in: PubMed
    Score: 0.025
  18. Danielson MA, Biemann HP, Koshland DE, Falke JJ. Attractant- and disulfide-induced conformational changes in the ligand binding domain of the chemotaxis aspartate receptor: a 19F NMR study. Biochemistry. 1994 May 24; 33(20):6100-9.
    View in: PubMed
    Score: 0.024
  19. Drake SK, Bourret RB, Luck LA, Simon MI, Falke JJ. Activation of the phosphosignaling protein CheY. I. Analysis of the phosphorylated conformation by 19F NMR and protein engineering. J Biol Chem. 1993 Jun 25; 268(18):13081-8.
    View in: PubMed
    Score: 0.023
  20. Li X, Fleetwood AD, Bayas C, Bilwes AM, Ortega DR, Falke JJ, Zhulin IB, Crane BR. The 3.2 ? resolution structure of a receptor: CheA:CheW signaling complex defines overlapping binding sites and key residue interactions within bacterial chemosensory arrays. Biochemistry. 2013 Jun 04; 52(22):3852-65.
    View in: PubMed
    Score: 0.022
  21. Needham JV, Chen TY, Falke JJ. Novel ion specificity of a carboxylate cluster Mg(II) binding site: strong charge selectivity and weak size selectivity. Biochemistry. 1993 Apr 06; 32(13):3363-7.
    View in: PubMed
    Score: 0.022
  22. Falke JJ, Snyder EE, Thatcher KC, Voertler CS. Quantitating and engineering the ion specificity of an EF-hand-like Ca2+ binding. Biochemistry. 1991 Sep 03; 30(35):8690-7.
    View in: PubMed
    Score: 0.020
  23. Luck LA, Falke JJ. Open conformation of a substrate-binding cleft: 19F NMR studies of cleft angle in the D-galactose chemosensory receptor. Biochemistry. 1991 Jul 02; 30(26):6484-90.
    View in: PubMed
    Score: 0.020
  24. Jaud S, Tobias DJ, Falke JJ, White SH. Self-induced docking site of a deeply embedded peripheral membrane protein. Biophys J. 2007 Jan 15; 92(2):517-24.
    View in: PubMed
    Score: 0.014
  25. Falke JJ, Kanes KJ, Chan SI. The minimal structure containing the band 3 anion transport site. A 35Cl NMR study. J Biol Chem. 1985 Oct 25; 260(24):13294-303.
    View in: PubMed
    Score: 0.013
  26. Falke JJ, Pace RJ, Chan SI. Chloride binding to the anion transport binding sites of band 3. A 35Cl NMR study. J Biol Chem. 1984 May 25; 259(10):6472-80.
    View in: PubMed
    Score: 0.012
  27. Falke JJ, Chan SI, Steiner M, Oesterhelt D, Towner P, Lanyi JK. Halide binding by the purified halorhodopsin chromoprotein. II. New chloride-binding sites revealed by 35Cl NMR. J Biol Chem. 1984 Feb 25; 259(4):2185-9.
    View in: PubMed
    Score: 0.012
  28. Nalefski EA, McDonagh T, Somers W, Seehra J, Falke JJ, Clark JD. Independent folding and ligand specificity of the C2 calcium-dependent lipid binding domain of cytosolic phospholipase A2. J Biol Chem. 1998 Jan 16; 273(3):1365-72.
    View in: PubMed
    Score: 0.008
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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