 Connection
Joseph Falke to Protein Structure, Tertiary
This is a "connection" page, showing publications Joseph Falke has written about Protein Structure, Tertiary.
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1.897 |
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Nalefski EA, Wisner MA, Chen JZ, Sprang SR, Fukuda M, Mikoshiba K, Falke JJ. C2 domains from different Ca2+ signaling pathways display functional and mechanistic diversity. Biochemistry. 2001 Mar 13; 40(10):3089-100.
Score: 0.149
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Nalefski EA, Slazas MM, Falke JJ. Ca2+-signaling cycle of a membrane-docking C2 domain. Biochemistry. 1997 Oct 07; 36(40):12011-8.
Score: 0.118
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Parkinson JS, Hazelbauer GL, Falke JJ. Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update. Trends Microbiol. 2015 May; 23(5):257-66.
Score: 0.099
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Ziemba BP, Li J, Landgraf KE, Knight JD, Voth GA, Falke JJ. Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-a. Biochemistry. 2014 Mar 18; 53(10):1697-713.
Score: 0.092
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Ziemba BP, Pilling C, Calleja V, Larijani B, Falke JJ. The PH domain of phosphoinositide-dependent kinase-1 exhibits a novel, phospho-regulated monomer-dimer equilibrium with important implications for kinase domain activation: single-molecule and ensemble studies. Biochemistry. 2013 Jul 16; 52(28):4820-9.
Score: 0.088
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Piasta KN, Ulliman CJ, Slivka PF, Crane BR, Falke JJ. Defining a key receptor-CheA kinase contact and elucidating its function in the membrane-bound bacterial chemosensory array: a disulfide mapping and TAM-IDS Study. Biochemistry. 2013 Jun 04; 52(22):3866-80.
Score: 0.087
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Chen HC, Ziemba BP, Landgraf KE, Corbin JA, Falke JJ. Membrane docking geometry of GRP1 PH domain bound to a target lipid bilayer: an EPR site-directed spin-labeling and relaxation study. PLoS One. 2012; 7(3):e33640.
Score: 0.080
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Ziemba BP, Knight JD, Falke JJ. Assembly of membrane-bound protein complexes: detection and analysis by single molecule diffusion. Biochemistry. 2012 Feb 28; 51(8):1638-47.
Score: 0.080
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Pilling C, Landgraf KE, Falke JJ. The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3). Biochemistry. 2011 Nov 15; 50(45):9845-56.
Score: 0.078
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Landgraf KE, Pilling C, Falke JJ. Molecular mechanism of an oncogenic mutation that alters membrane targeting: Glu17Lys modifies the PIP lipid specificity of the AKT1 PH domain. Biochemistry. 2008 Nov 25; 47(47):12260-9.
Score: 0.064
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Landgraf KE, Malmberg NJ, Falke JJ. Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study. Biochemistry. 2008 Aug 12; 47(32):8301-16.
Score: 0.062
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Corbin JA, Evans JH, Landgraf KE, Falke JJ. Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity. Biochemistry. 2007 Apr 10; 46(14):4322-36.
Score: 0.057
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Bass RB, Miller AS, Gloor SL, Falke JJ. The PICM chemical scanning method for identifying domain-domain and protein-protein interfaces: applications to the core signaling complex of E. coli chemotaxis. Methods Enzymol. 2007; 423:3-24.
Score: 0.056
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Bass RB, Butler SL, Chervitz SA, Gloor SL, Falke JJ. Use of site-directed cysteine and disulfide chemistry to probe protein structure and dynamics: applications to soluble and transmembrane receptors of bacterial chemotaxis. Methods Enzymol. 2007; 423:25-51.
Score: 0.056
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Miller AS, Kohout SC, Gilman KA, Falke JJ. CheA Kinase of bacterial chemotaxis: chemical mapping of four essential docking sites. Biochemistry. 2006 Jul 25; 45(29):8699-711.
Score: 0.054
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Evans JH, Murray D, Leslie CC, Falke JJ. Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain. Mol Biol Cell. 2006 Jan; 17(1):56-66.
Score: 0.051
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Winston SE, Mehan R, Falke JJ. Evidence that the adaptation region of the aspartate receptor is a dynamic four-helix bundle: cysteine and disulfide scanning studies. Biochemistry. 2005 Sep 27; 44(38):12655-66.
Score: 0.051
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Coleman MD, Bass RB, Mehan RS, Falke JJ. Conserved glycine residues in the cytoplasmic domain of the aspartate receptor play essential roles in kinase coupling and on-off switching. Biochemistry. 2005 May 31; 44(21):7687-95.
Score: 0.050
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Starrett DJ, Falke JJ. Adaptation mechanism of the aspartate receptor: electrostatics of the adaptation subdomain play a key role in modulating kinase activity. Biochemistry. 2005 Feb 08; 44(5):1550-60.
Score: 0.049
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Malmberg NJ, Falke JJ. Use of EPR power saturation to analyze the membrane-docking geometries of peripheral proteins: applications to C2 domains. Annu Rev Biophys Biomol Struct. 2005; 34:71-90.
Score: 0.049
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Corbin JA, Dirkx RA, Falke JJ. GRP1 pleckstrin homology domain: activation parameters and novel search mechanism for rare target lipid. Biochemistry. 2004 Dec 28; 43(51):16161-73.
Score: 0.049
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Malmberg NJ, Varma S, Jakobsson E, Falke JJ. Ca2+ activation of the cPLA2 C2 domain: ordered binding of two Ca2+ ions with positive cooperativity. Biochemistry. 2004 Dec 28; 43(51):16320-8.
Score: 0.049
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Malmberg NJ, Van Buskirk DR, Falke JJ. Membrane-docking loops of the cPLA2 C2 domain: detailed structural analysis of the protein-membrane interface via site-directed spin-labeling. Biochemistry. 2003 Nov 18; 42(45):13227-40.
Score: 0.045
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Mehan RS, White NC, Falke JJ. Mapping out regions on the surface of the aspartate receptor that are essential for kinase activation. Biochemistry. 2003 Mar 18; 42(10):2952-9.
Score: 0.043
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Kohout SC, Corbal?n-Garc?a S, G?mez-Fern?ndez JC, Falke JJ. C2 domain of protein kinase C alpha: elucidation of the membrane docking surface by site-directed fluorescence and spin labeling. Biochemistry. 2003 Feb 11; 42(5):1254-65.
Score: 0.043
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Falke JJ. Enzymology. A moving story. Science. 2002 Feb 22; 295(5559):1480-1.
Score: 0.040
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Nalefski EA, Falke JJ. Use of fluorescence resonance energy transfer to monitor Ca(2+)-triggered membrane docking of C2 domains. Methods Mol Biol. 2002; 172:295-303.
Score: 0.039
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Nalefski EA, Falke JJ. Location of the membrane-docking face on the Ca2+-activated C2 domain of cytosolic phospholipase A2. Biochemistry. 1998 Dec 22; 37(51):17642-50.
Score: 0.032
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Lai CL, Srivastava A, Pilling C, Chase AR, Falke JJ, Voth GA. Molecular mechanism of membrane binding of the GRP1 PH domain. J Mol Biol. 2013 Sep 09; 425(17):3073-90.
Score: 0.022
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Li X, Fleetwood AD, Bayas C, Bilwes AM, Ortega DR, Falke JJ, Zhulin IB, Crane BR. The 3.2 ? resolution structure of a receptor: CheA:CheW signaling complex defines overlapping binding sites and key residue interactions within bacterial chemosensory arrays. Biochemistry. 2013 Jun 04; 52(22):3852-65.
Score: 0.022
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Brandt DS, Coffman MD, Falke JJ, Knight JD. Hydrophobic contributions to the membrane docking of synaptotagmin 7 C2A domain: mechanistic contrast between isoforms 1 and 7. Biochemistry. 2012 Oct 02; 51(39):7654-64.
Score: 0.021
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Hazelbauer GL, Falke JJ, Parkinson JS. Bacterial chemoreceptors: high-performance signaling in networked arrays. Trends Biochem Sci. 2008 Jan; 33(1):9-19.
Score: 0.015
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Frazier AA, Wisner MA, Malmberg NJ, Victor KG, Fanucci GE, Nalefski EA, Falke JJ, Cafiso DS. Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling. Biochemistry. 2002 May 21; 41(20):6282-92.
Score: 0.010
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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