 Connection
Joseph Falke to Chemotaxis
This is a "connection" page, showing publications Joseph Falke has written about Chemotaxis.
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Connection Strength |
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6.852 |
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Parkinson JS, Hazelbauer GL, Falke JJ. Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update. Trends Microbiol. 2015 May; 23(5):257-66.
Score: 0.457
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Falke JJ, Piasta KN. Architecture and signal transduction mechanism of the bacterial chemosensory array: progress, controversies, and challenges. Curr Opin Struct Biol. 2014 Dec; 29:85-94.
Score: 0.443
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Piasta KN, Falke JJ. Increasing and decreasing the ultrastability of bacterial chemotaxis core signaling complexes by modifying protein-protein contacts. Biochemistry. 2014 Sep 09; 53(35):5592-600.
Score: 0.438
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Falke JJ, Ziemba BP. Interplay between phosphoinositide lipids and calcium signals at the leading edge of chemotaxing ameboid cells. Chem Phys Lipids. 2014 Sep; 182:73-9.
Score: 0.421
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Piasta KN, Ulliman CJ, Slivka PF, Crane BR, Falke JJ. Defining a key receptor-CheA kinase contact and elucidating its function in the membrane-bound bacterial chemosensory array: a disulfide mapping and TAM-IDS Study. Biochemistry. 2013 Jun 04; 52(22):3866-80.
Score: 0.402
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Swain KE, Gonzalez MA, Falke JJ. Engineered socket study of signaling through a four-helix bundle: evidence for a yin-yang mechanism in the kinase control module of the aspartate receptor. Biochemistry. 2009 Oct 06; 48(39):9266-77.
Score: 0.312
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Erbse AH, Falke JJ. The core signaling proteins of bacterial chemotaxis assemble to form an ultrastable complex. Biochemistry. 2009 Jul 28; 48(29):6975-87.
Score: 0.308
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Miller AS, Kohout SC, Gilman KA, Falke JJ. CheA Kinase of bacterial chemotaxis: chemical mapping of four essential docking sites. Biochemistry. 2006 Jul 25; 45(29):8699-711.
Score: 0.250
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Coleman MD, Bass RB, Mehan RS, Falke JJ. Conserved glycine residues in the cytoplasmic domain of the aspartate receptor play essential roles in kinase coupling and on-off switching. Biochemistry. 2005 May 31; 44(21):7687-95.
Score: 0.231
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Starrett DJ, Falke JJ. Adaptation mechanism of the aspartate receptor: electrostatics of the adaptation subdomain play a key role in modulating kinase activity. Biochemistry. 2005 Feb 08; 44(5):1550-60.
Score: 0.226
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Miller AS, Falke JJ. Side chains at the membrane-water interface modulate the signaling state of a transmembrane receptor. Biochemistry. 2004 Feb 24; 43(7):1763-70.
Score: 0.212
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Miller AF, Falke JJ. Chemotaxis receptors and signaling. Adv Protein Chem. 2004; 68:393-444.
Score: 0.210
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Mehan RS, White NC, Falke JJ. Mapping out regions on the surface of the aspartate receptor that are essential for kinase activation. Biochemistry. 2003 Mar 18; 42(10):2952-9.
Score: 0.198
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Bornhorst JA, Falke JJ. Quantitative analysis of aspartate receptor signaling complex reveals that the homogeneous two-state model is inadequate: development of a heterogeneous two-state model. J Mol Biol. 2003 Mar 07; 326(5):1597-614.
Score: 0.198
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Bornhorst JA, Falke JJ. Evidence that both ligand binding and covalent adaptation drive a two-state equilibrium in the aspartate receptor signaling complex. J Gen Physiol. 2001 Dec; 118(6):693-710.
Score: 0.181
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Bornhorst JA, Falke JJ. Attractant regulation of the aspartate receptor-kinase complex: limited cooperative interactions between receptors and effects of the receptor modification state. Biochemistry. 2000 Aug 08; 39(31):9486-93.
Score: 0.166
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Falke JJ, Kim SH. Structure of a conserved receptor domain that regulates kinase activity: the cytoplasmic domain of bacterial taxis receptors. Curr Opin Struct Biol. 2000 Aug; 10(4):462-9.
Score: 0.165
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Bass RB, Coleman MD, Falke JJ. Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: cysteine and disulfide scanning studies. Biochemistry. 1999 Jul 20; 38(29):9317-27.
Score: 0.154
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Ziemba BP, Falke JJ. A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages. PLoS One. 2018; 13(5):e0196678.
Score: 0.141
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Danielson MA, Bass RB, Falke JJ. Cysteine and disulfide scanning reveals a regulatory alpha-helix in the cytoplasmic domain of the aspartate receptor. J Biol Chem. 1997 Dec 26; 272(52):32878-88.
Score: 0.138
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Falke JJ, Bass RB, Butler SL, Chervitz SA, Danielson MA. The two-component signaling pathway of bacterial chemotaxis: a molecular view of signal transduction by receptors, kinases, and adaptation enzymes. Annu Rev Cell Dev Biol. 1997; 13:457-512.
Score: 0.129
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Chervitz SA, Falke JJ. Lock on/off disulfides identify the transmembrane signaling helix of the aspartate receptor. J Biol Chem. 1995 Oct 13; 270(41):24043-53.
Score: 0.119
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Danielson MA, Biemann HP, Koshland DE, Falke JJ. Attractant- and disulfide-induced conformational changes in the ligand binding domain of the chemotaxis aspartate receptor: a 19F NMR study. Biochemistry. 1994 May 24; 33(20):6100-9.
Score: 0.108
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Natale AM, Duplantis JL, Piasta KN, Falke JJ. Structure, function, and on-off switching of a core unit contact between CheA kinase and CheW adaptor protein in the bacterial chemosensory array: A disulfide mapping and mutagenesis study. Biochemistry. 2013 Nov 05; 52(44):7753-65.
Score: 0.103
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Drake SK, Bourret RB, Luck LA, Simon MI, Falke JJ. Activation of the phosphosignaling protein CheY. I. Analysis of the phosphorylated conformation by 19F NMR and protein engineering. J Biol Chem. 1993 Jun 25; 268(18):13081-8.
Score: 0.101
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Bourret RB, Drake SK, Chervitz SA, Simon MI, Falke JJ. Activation of the phosphosignaling protein CheY. II. Analysis of activated mutants by 19F NMR and protein engineering. J Biol Chem. 1993 Jun 25; 268(18):13089-96.
Score: 0.101
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Slivka PF, Falke JJ. Isolated bacterial chemosensory array possesses quasi- and ultrastable components: functional links between array stability, cooperativity, and order. Biochemistry. 2012 Dec 21; 51(51):10218-28.
Score: 0.097
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Careaga CL, Falke JJ. Thermal motions of surface alpha-helices in the D-galactose chemosensory receptor. Detection by disulfide trapping. J Mol Biol. 1992 Aug 20; 226(4):1219-35.
Score: 0.095
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Erbse AH, Berlinberg AJ, Cheung CY, Leung WY, Falke JJ. OS-FRET: a new one-sample method for improved FRET measurements. Biochemistry. 2011 Feb 01; 50(4):451-7.
Score: 0.085
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Hazelbauer GL, Falke JJ, Parkinson JS. Bacterial chemoreceptors: high-performance signaling in networked arrays. Trends Biochem Sci. 2008 Jan; 33(1):9-19.
Score: 0.069
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Evans JH, Falke JJ. Ca2+ influx is an essential component of the positive-feedback loop that maintains leading-edge structure and activity in macrophages. Proc Natl Acad Sci U S A. 2007 Oct 09; 104(41):16176-81.
Score: 0.068
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Falke JJ, Koshland DE. Global flexibility in a sensory receptor: a site-directed cross-linking approach. Science. 1987 Sep 25; 237(4822):1596-600.
Score: 0.068
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Endres RG, Falke JJ, Wingreen NS. Chemotaxis receptor complexes: from signaling to assembly. PLoS Comput Biol. 2007 Jul; 3(7):e150.
Score: 0.067
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Bass RB, Miller AS, Gloor SL, Falke JJ. The PICM chemical scanning method for identifying domain-domain and protein-protein interfaces: applications to the core signaling complex of E. coli chemotaxis. Methods Enzymol. 2007; 423:3-24.
Score: 0.065
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Bass RB, Butler SL, Chervitz SA, Gloor SL, Falke JJ. Use of site-directed cysteine and disulfide chemistry to probe protein structure and dynamics: applications to soluble and transmembrane receptors of bacterial chemotaxis. Methods Enzymol. 2007; 423:25-51.
Score: 0.065
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Falke JJ. Cooperativity between bacterial chemotaxis receptors. Proc Natl Acad Sci U S A. 2002 May 14; 99(10):6530-2.
Score: 0.047
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Trammell MA, Falke JJ. Identification of a site critical for kinase regulation on the central processing unit (CPU) helix of the aspartate receptor. Biochemistry. 1999 Jan 05; 38(1):329-36.
Score: 0.037
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Bass RB, Falke JJ. Detection of a conserved alpha-helix in the kinase-docking region of the aspartate receptor by cysteine and disulfide scanning. J Biol Chem. 1998 Sep 25; 273(39):25006-14.
Score: 0.036
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Butler SL, Falke JJ. Cysteine and disulfide scanning reveals two amphiphilic helices in the linker region of the aspartate chemoreceptor. Biochemistry. 1998 Jul 28; 37(30):10746-56.
Score: 0.036
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Danielson MA, Falke JJ. Use of 19F NMR to probe protein structure and conformational changes. Annu Rev Biophys Biomol Struct. 1996; 25:163-95.
Score: 0.030
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Falke JJ, Blair DF, Silhavy TJ, Schmitt R. BLAST 1995: international conference on bacterial locomotion and signal transduction. Mol Microbiol. 1995 Jun; 16(6):1037-50.
Score: 0.029
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Briegel A, Wong ML, Hodges HL, Oikonomou CM, Piasta KN, Harris MJ, Fowler DJ, Thompson LK, Falke JJ, Kiessling LL, Jensen GJ. New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography. Biochemistry. 2014 Mar 18; 53(10):1575-85.
Score: 0.027
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Falke JJ, Dernburg AF, Sternberg DA, Zalkin N, Milligan DL, Koshland DE. Structure of a bacterial sensory receptor. A site-directed sulfhydryl study. J Biol Chem. 1988 Oct 15; 263(29):14850-8.
Score: 0.018
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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