 Connection
Joseph Falke to Models, Molecular
This is a "connection" page, showing publications Joseph Falke has written about Models, Molecular.
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Connection Strength |
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1.792 |
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Buckles TC, Ziemba BP, Masson GR, Williams RL, Falke JJ. Single-Molecule Study Reveals How Receptor and Ras Synergistically Activate PI3Ka and PIP3 Signaling. Biophys J. 2017 Dec 05; 113(11):2396-2405.
Score: 0.109
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Ziemba BP, Swisher GH, Masson G, Burke JE, Williams RL, Falke JJ. Regulation of a Coupled MARCKS-PI3K Lipid Kinase Circuit by Calmodulin: Single-Molecule Analysis of a Membrane-Bound Signaling Module. Biochemistry. 2016 Nov 22; 55(46):6395-6405.
Score: 0.101
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Ziemba BP, Burke JE, Masson G, Williams RL, Falke JJ. Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway. Biophys J. 2016 04 26; 110(8):1811-1825.
Score: 0.097
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Parkinson JS, Hazelbauer GL, Falke JJ. Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update. Trends Microbiol. 2015 May; 23(5):257-66.
Score: 0.090
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Piasta KN, Falke JJ. Increasing and decreasing the ultrastability of bacterial chemotaxis core signaling complexes by modifying protein-protein contacts. Biochemistry. 2014 Sep 09; 53(35):5592-600.
Score: 0.087
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Natale AM, Duplantis JL, Piasta KN, Falke JJ. Structure, function, and on-off switching of a core unit contact between CheA kinase and CheW adaptor protein in the bacterial chemosensory array: A disulfide mapping and mutagenesis study. Biochemistry. 2013 Nov 05; 52(44):7753-65.
Score: 0.082
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Chen HC, Ziemba BP, Landgraf KE, Corbin JA, Falke JJ. Membrane docking geometry of GRP1 PH domain bound to a target lipid bilayer: an EPR site-directed spin-labeling and relaxation study. PLoS One. 2012; 7(3):e33640.
Score: 0.073
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Pilling C, Landgraf KE, Falke JJ. The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3). Biochemistry. 2011 Nov 15; 50(45):9845-56.
Score: 0.071
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Lai CL, Landgraf KE, Voth GA, Falke JJ. Membrane docking geometry and target lipid stoichiometry of membrane-bound PKCa C2 domain: a combined molecular dynamics and experimental study. J Mol Biol. 2010 Sep 17; 402(2):301-10.
Score: 0.065
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Gloor SL, Falke JJ. Thermal domain motions of CheA kinase in solution: Disulfide trapping reveals the motional constraints leading to trans-autophosphorylation. Biochemistry. 2009 Apr 28; 48(16):3631-44.
Score: 0.060
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Bass RB, Miller AS, Gloor SL, Falke JJ. The PICM chemical scanning method for identifying domain-domain and protein-protein interfaces: applications to the core signaling complex of E. coli chemotaxis. Methods Enzymol. 2007; 423:3-24.
Score: 0.051
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Jaud S, Tobias DJ, Falke JJ, White SH. Self-induced docking site of a deeply embedded peripheral membrane protein. Biophys J. 2007 Jan 15; 92(2):517-24.
Score: 0.050
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Miller AS, Kohout SC, Gilman KA, Falke JJ. CheA Kinase of bacterial chemotaxis: chemical mapping of four essential docking sites. Biochemistry. 2006 Jul 25; 45(29):8699-711.
Score: 0.050
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Evans JH, Murray D, Leslie CC, Falke JJ. Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain. Mol Biol Cell. 2006 Jan; 17(1):56-66.
Score: 0.047
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Winston SE, Mehan R, Falke JJ. Evidence that the adaptation region of the aspartate receptor is a dynamic four-helix bundle: cysteine and disulfide scanning studies. Biochemistry. 2005 Sep 27; 44(38):12655-66.
Score: 0.047
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Malmberg NJ, Falke JJ. Use of EPR power saturation to analyze the membrane-docking geometries of peripheral proteins: applications to C2 domains. Annu Rev Biophys Biomol Struct. 2005; 34:71-90.
Score: 0.044
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Miller AF, Falke JJ. Chemotaxis receptors and signaling. Adv Protein Chem. 2004; 68:393-444.
Score: 0.041
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Malmberg NJ, Van Buskirk DR, Falke JJ. Membrane-docking loops of the cPLA2 C2 domain: detailed structural analysis of the protein-membrane interface via site-directed spin-labeling. Biochemistry. 2003 Nov 18; 42(45):13227-40.
Score: 0.041
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Mehan RS, White NC, Falke JJ. Mapping out regions on the surface of the aspartate receptor that are essential for kinase activation. Biochemistry. 2003 Mar 18; 42(10):2952-9.
Score: 0.039
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Falke JJ. Enzymology. A moving story. Science. 2002 Feb 22; 295(5559):1480-1.
Score: 0.036
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Bass RB, Coleman MD, Falke JJ. Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: cysteine and disulfide scanning studies. Biochemistry. 1999 Jul 20; 38(29):9317-27.
Score: 0.030
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Bass RB, Falke JJ. The aspartate receptor cytoplasmic domain: in situ chemical analysis of structure, mechanism and dynamics. Structure. 1999 Jul 15; 7(7):829-40.
Score: 0.030
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Nalefski EA, Falke JJ. Location of the membrane-docking face on the Ca2+-activated C2 domain of cytosolic phospholipase A2. Biochemistry. 1998 Dec 22; 37(51):17642-50.
Score: 0.029
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Butler SL, Falke JJ. Cysteine and disulfide scanning reveals two amphiphilic helices in the linker region of the aspartate chemoreceptor. Biochemistry. 1998 Jul 28; 37(30):10746-56.
Score: 0.028
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Danielson MA, Bass RB, Falke JJ. Cysteine and disulfide scanning reveals a regulatory alpha-helix in the cytoplasmic domain of the aspartate receptor. J Biol Chem. 1997 Dec 26; 272(52):32878-88.
Score: 0.027
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Drake SK, Zimmer MA, Kundrot C, Falke JJ. Molecular tuning of an EF-hand-like calcium binding loop. Contributions of the coordinating side chain at loop position 3. J Gen Physiol. 1997 Aug; 110(2):173-84.
Score: 0.027
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Drake SK, Lee KL, Falke JJ. Tuning the equilibrium ion affinity and selectivity of the EF-hand calcium binding motif: substitutions at the gateway position. Biochemistry. 1996 May 28; 35(21):6697-705.
Score: 0.024
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Chervitz SA, Falke JJ. Molecular mechanism of transmembrane signaling by the aspartate receptor: a model. Proc Natl Acad Sci U S A. 1996 Mar 19; 93(6):2545-50.
Score: 0.024
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Drake SK, Falke JJ. Kinetic tuning of the EF-hand calcium binding motif: the gateway residue independently adjusts (i) barrier height and (ii) equilibrium. Biochemistry. 1996 Feb 13; 35(6):1753-60.
Score: 0.024
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Danielson MA, Falke JJ. Use of 19F NMR to probe protein structure and conformational changes. Annu Rev Biophys Biomol Struct. 1996; 25:163-95.
Score: 0.024
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Careaga CL, Sutherland J, Sabeti J, Falke JJ. Large amplitude twisting motions of an interdomain hinge: a disulfide trapping study of the galactose-glucose binding protein. Biochemistry. 1995 Mar 07; 34(9):3048-55.
Score: 0.022
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Falke JJ, Drake SK, Hazard AL, Peersen OB. Molecular tuning of ion binding to calcium signaling proteins. Q Rev Biophys. 1994 Aug; 27(3):219-90.
Score: 0.022
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Danielson MA, Biemann HP, Koshland DE, Falke JJ. Attractant- and disulfide-induced conformational changes in the ligand binding domain of the chemotaxis aspartate receptor: a 19F NMR study. Biochemistry. 1994 May 24; 33(20):6100-9.
Score: 0.021
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Briegel A, Wong ML, Hodges HL, Oikonomou CM, Piasta KN, Harris MJ, Fowler DJ, Thompson LK, Falke JJ, Kiessling LL, Jensen GJ. New insights into bacterial chemoreceptor array structure and assembly from electron cryotomography. Biochemistry. 2014 Mar 18; 53(10):1575-85.
Score: 0.021
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Renner M, Danielson MA, Falke JJ. Kinetic control of Ca(II) signaling: tuning the ion dissociation rates of EF-hand Ca(II) binding sites. Proc Natl Acad Sci U S A. 1993 Jul 15; 90(14):6493-7.
Score: 0.020
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Lai CL, Srivastava A, Pilling C, Chase AR, Falke JJ, Voth GA. Molecular mechanism of membrane binding of the GRP1 PH domain. J Mol Biol. 2013 Sep 09; 425(17):3073-90.
Score: 0.020
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Li X, Fleetwood AD, Bayas C, Bilwes AM, Ortega DR, Falke JJ, Zhulin IB, Crane BR. The 3.2 ? resolution structure of a receptor: CheA:CheW signaling complex defines overlapping binding sites and key residue interactions within bacterial chemosensory arrays. Biochemistry. 2013 Jun 04; 52(22):3852-65.
Score: 0.020
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Careaga CL, Falke JJ. Thermal motions of surface alpha-helices in the D-galactose chemosensory receptor. Detection by disulfide trapping. J Mol Biol. 1992 Aug 20; 226(4):1219-35.
Score: 0.019
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Falke JJ, Luck LA, Scherrer J. 19F nuclear magnetic resonance studies of aqueous and transmembrane receptors. Examples from the Escherichia coli chemosensory pathway. Biophys J. 1992 Apr; 62(1):82-6.
Score: 0.018
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Luck LA, Falke JJ. Open conformation of a substrate-binding cleft: 19F NMR studies of cleft angle in the D-galactose chemosensory receptor. Biochemistry. 1991 Jul 02; 30(26):6484-90.
Score: 0.017
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Hutchinson MR, Loram LC, Zhang Y, Shridhar M, Rezvani N, Berkelhammer D, Phipps S, Foster PS, Landgraf K, Falke JJ, Rice KC, Maier SF, Yin H, Watkins LR. Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity. Neuroscience. 2010 Jun 30; 168(2):551-63.
Score: 0.016
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Hazelbauer GL, Falke JJ, Parkinson JS. Bacterial chemoreceptors: high-performance signaling in networked arrays. Trends Biochem Sci. 2008 Jan; 33(1):9-19.
Score: 0.014
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Frazier AA, Wisner MA, Malmberg NJ, Victor KG, Fanucci GE, Nalefski EA, Falke JJ, Cafiso DS. Membrane orientation and position of the C2 domain from cPLA2 by site-directed spin labeling. Biochemistry. 2002 May 21; 41(20):6282-92.
Score: 0.009
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Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
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