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Connection

Joseph Falke to Protein Kinase C-alpha

This is a "connection" page, showing publications Joseph Falke has written about Protein Kinase C-alpha.

 
Connection Strength
 
 
 
3.335
 
  1. Gordon MT, Ziemba BP, Falke JJ. PDK1:PKCa heterodimer association-dissociation dynamics in single-molecule diffusion tracks on a target membrane. Biophys J. 2023 06 06; 122(11):2301-2310.
    View in: PubMed
    Score: 0.848
  2. Ziemba BP, Burke JE, Masson G, Williams RL, Falke JJ. Regulation of PI3K by PKC and MARCKS: Single-Molecule Analysis of a Reconstituted Signaling Pathway. Biophys J. 2016 04 26; 110(8):1811-1825.
    View in: PubMed
    Score: 0.531
  3. Ziemba BP, Li J, Landgraf KE, Knight JD, Voth GA, Falke JJ. Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-a. Biochemistry. 2014 Mar 18; 53(10):1697-713.
    View in: PubMed
    Score: 0.457
  4. Lai CL, Landgraf KE, Voth GA, Falke JJ. Membrane docking geometry and target lipid stoichiometry of membrane-bound PKCa C2 domain: a combined molecular dynamics and experimental study. J Mol Biol. 2010 Sep 17; 402(2):301-10.
    View in: PubMed
    Score: 0.356
  5. Landgraf KE, Malmberg NJ, Falke JJ. Effect of PIP2 binding on the membrane docking geometry of PKC alpha C2 domain: an EPR site-directed spin-labeling and relaxation study. Biochemistry. 2008 Aug 12; 47(32):8301-16.
    View in: PubMed
    Score: 0.309
  6. Corbin JA, Evans JH, Landgraf KE, Falke JJ. Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity. Biochemistry. 2007 Apr 10; 46(14):4322-36.
    View in: PubMed
    Score: 0.282
  7. Evans JH, Murray D, Leslie CC, Falke JJ. Specific translocation of protein kinase Calpha to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain. Mol Biol Cell. 2006 Jan; 17(1):56-66.
    View in: PubMed
    Score: 0.256
  8. Li J, Ziemba BP, Falke JJ, Voth GA. Interactions of protein kinase C-a C1A and C1B domains with membranes: a combined computational and experimental study. J Am Chem Soc. 2014 Aug 20; 136(33):11757-66.
    View in: PubMed
    Score: 0.118
  9. Evans JH, Falke JJ. Ca2+ influx is an essential component of the positive-feedback loop that maintains leading-edge structure and activity in macrophages. Proc Natl Acad Sci U S A. 2007 Oct 09; 104(41):16176-81.
    View in: PubMed
    Score: 0.073
  10. Kohout SC, Corbal?n-Garc?a S, G?mez-Fern?ndez JC, Falke JJ. C2 domain of protein kinase C alpha: elucidation of the membrane docking surface by site-directed fluorescence and spin labeling. Biochemistry. 2003 Feb 11; 42(5):1254-65.
    View in: PubMed
    Score: 0.053
  11. Kohout SC, Corbal?n-Garc?a S, Torrecillas A, Gom?z-Fernand?z JC, Falke JJ. C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state. Biochemistry. 2002 Sep 24; 41(38):11411-24.
    View in: PubMed
    Score: 0.052
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

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