 Cyclophilin A
"Cyclophilin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 17-KDa cytoplasmic PEPTIDYLPROLYL ISOMERASE involved in immunoregulation. It is a member of the cyclophilin family of proteins that binds to CYCLOSPORINE.
| Descriptor ID |
D021984
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| MeSH Number(s) |
D08.811.399.325.500.400.300.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclophilin A".
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This graph shows the total number of publications written about "Cyclophilin A" by people in this website by year, and whether "Cyclophilin A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 3 | 0 | 3 | | 2005 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2009 | 2 | 0 | 2 | | 2010 | 2 | 0 | 2 | | 2012 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 2 | 0 | 2 | | 2017 | 2 | 0 | 2 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclophilin A" by people in Profiles.
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Morrison JH, Miller C, Bankers L, Crameri G, Wang LF, Poeschla EM. A Potent Postentry Restriction to Primate Lentiviruses in a Yinpterochiropteran Bat. mBio. 2020 09 15; 11(5).
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Nichols PJ, Born A, Henen MA, Strotz D, Orts J, Olsson S, G?ntert P, Chi CN, V?geli B. The Exact Nuclear Overhauser Enhancement: Recent Advances. Molecules. 2017 Jul 14; 22(7).
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Holliday MJ, Camilloni C, Armstrong GS, Vendruscolo M, Eisenmesser EZ. Networks of Dynamic Allostery Regulate Enzyme Function. Structure. 2017 02 07; 25(2):276-286.
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Ngure M, Issur M, Shkriabai N, Liu HW, Cosa G, Kvaratskhelia M, G?tte M. Interactions of the Disordered Domain II of Hepatitis C Virus NS5A with Cyclophilin A, NS5B, and Viral RNA Show Extensive Overlap. ACS Infect Dis. 2016 11 11; 2(11):839-851.
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Doshi U, Holliday MJ, Eisenmesser EZ, Hamelberg D. Dynamical network of residue-residue contacts reveals coupled allosteric effects in recognition, catalysis, and mutation. Proc Natl Acad Sci U S A. 2016 Apr 26; 113(17):4735-40.
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Camilloni C, Sahakyan AB, Holliday MJ, Isern NG, Zhang F, Eisenmesser EZ, Vendruscolo M. Cyclophilin A catalyzes proline isomerization by an electrostatic handle mechanism. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10203-8.
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Holliday MJ, Zhang F, Isern NG, Armstrong GS, Eisenmesser EZ. 1H, 13C, and 15N backbone and side chain resonance assignments of thermophilic Geobacillus kaustophilus cyclophilin-A. Biomol NMR Assign. 2014 Apr; 8(1):23-7.
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Bienkowska-Haba M, Williams C, Kim SM, Garcea RL, Sapp M. Cyclophilins facilitate dissociation of the human papillomavirus type 16 capsid protein L1 from the L2/DNA complex following virus entry. J Virol. 2012 Sep; 86(18):9875-87.
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Bosco DA, Eisenmesser EZ, Clarkson MW, Wolf-Watz M, Labeikovsky W, Millet O, Kern D. Dissecting the microscopic steps of the cyclophilin A enzymatic cycle on the biological HIV-1 capsid substrate by NMR. J Mol Biol. 2010 Nov 12; 403(5):723-38.
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Yurchenko V, Constant S, Eisenmesser E, Bukrinsky M. Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics. Clin Exp Immunol. 2010 Jun; 160(3):305-17.
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