 Protein Kinase C beta
"Protein Kinase C beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
PKC beta encodes two proteins (PKCB1 and PKCBII) generated by alternative splicing of C-terminal exons. It is widely distributed with wide-ranging roles in processes such as B-cell receptor regulation, oxidative stress-induced apoptosis, androgen receptor-dependent transcriptional regulation, insulin signaling, and endothelial cell proliferation.
| Descriptor ID |
D064546
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| MeSH Number(s) |
D08.811.913.696.620.682.700.725.049
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| Concept/Terms |
Protein Kinase C beta2- Protein Kinase C beta2
- PKCbeta2
- Protein Kinase C-beta(II)
- PKCBII
- PKC-beta II
- PKC beta II
- Protein Kinase C beta I
- Protein Kinase C-beta (II)
- PKC beta 2
- beta 2, PKC
- Protein Kinase C beta II
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Below are MeSH descriptors whose meaning is more general than "Protein Kinase C beta".
Below are MeSH descriptors whose meaning is more specific than "Protein Kinase C beta".
This graph shows the total number of publications written about "Protein Kinase C beta" by people in this website by year, and whether "Protein Kinase C beta" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 1999 | 0 | 3 | 3 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 3 | 3 | | 2002 | 0 | 3 | 3 | | 2005 | 0 | 1 | 1 | | 2008 | 0 | 3 | 3 | | 2014 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein Kinase C beta" by people in Profiles.
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Friesen RH, Slavov D, Miyamoto SD, John Ing R, LaRiviere WB, Taylor MRG. Lack of Association Between Adrenoreceptor Genotype and the Vasoconstriction Response to Dexmedetomidine. Semin Cardiothorac Vasc Anesth. 2017 Dec; 21(4):341-344.
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Li J, Ziemba BP, Falke JJ, Voth GA. Interactions of protein kinase C-a C1A and C1B domains with membranes: a combined computational and experimental study. J Am Chem Soc. 2014 Aug 20; 136(33):11757-66.
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Matsuo Y, Oberbach A, Till H, Inge TH, Wabitsch M, Moss A, Jehmlich N, V?lker U, M?ller U, Siegfried W, Kanesawa N, Kurabayashi M, Schuler G, Linke A, Adams V. Impaired HDL function in obese adolescents: impact of lifestyle intervention and bariatric surgery. Obesity (Silver Spring). 2013 Dec; 21(12):E687-95.
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Petrovic D, Stamataki Z, Dempsey E, Golden-Mason L, Freeley M, Doherty D, Prichard D, Keogh C, Conroy J, Mitchell S, Volkov Y, McKeating JA, O'Farrelly C, Kelleher D, Long A. Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion. Hepatology. 2011 Jun; 53(6):1846-53.
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Tammali R, Reddy AB, Ramana KV, Petrash JM, Srivastava SK. Aldose reductase deficiency in mice prevents azoxymethane-induced colonic preneoplastic aberrant crypt foci formation. Carcinogenesis. 2009 May; 30(5):799-807.
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Cree MG, Zwetsloot JJ, Herndon DN, Newcomer BR, Fram RY, Angel C, Green JM, Dohm GL, Sun D, Aarsland A, Wolfe RR. Insulin sensitivity is related to fat oxidation and protein kinase C activity in children with acute burn injury. J Burn Care Res. 2008 Jul-Aug; 29(4):585-94.
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Goldspink P, Ruch S, Los T, Buttrick P, Garc?a J. Maladaptation of calcium homoeostasis in aging cardiac myocytes. Pflugers Arch. 2008 Jun; 456(3):479-87.
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Camidge DR, Gail Eckhardt S, Gore L, O'Bryant CL, Leong S, Basche M, Holden SN, Musib L, Baldwin J, Darstein C, Thornton D, Finn RS, Britten CD. A phase I safety, tolerability, and pharmacokinetic study of enzastaurin combined with capecitabine in patients with advanced solid tumors. Anticancer Drugs. 2008 Jan; 19(1):77-84.
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Volkov Y, Long A, Freeley M, Golden-Mason L, O'Farrelly C, Murphy A, Kelleher D. The hepatitis C envelope 2 protein inhibits LFA-1-transduced protein kinase C signaling for T-lymphocyte migration. Gastroenterology. 2006 Feb; 130(2):482-92.
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Joy SV, Scates AC, Bearelly S, Dar M, Taulien CA, Goebel JA, Cooney MJ. Ruboxistaurin, a protein kinase C beta inhibitor, as an emerging treatment for diabetes microvascular complications. Ann Pharmacother. 2005 Oct; 39(10):1693-9.
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