Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christian Young

Concepts (308)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Carcinoma, Squamous Cell
11
2026
641
2.040
Why?
Head and Neck Neoplasms
10
2026
561
1.920
Why?
Mammary Neoplasms, Experimental
5
2025
62
1.540
Why?
Class I Phosphatidylinositol 3-Kinases
6
2025
108
1.370
Why?
Phosphatidylinositol 3-Kinases
9
2022
382
1.110
Why?
Keratin-15
2
2025
16
1.080
Why?
Receptor, ErbB-3
7
2017
48
1.040
Why?
Mouth Neoplasms
3
2023
90
1.010
Why?
Breast Neoplasms
12
2017
2382
0.940
Why?
Smad7 Protein
6
2026
20
0.840
Why?
Cell Line, Tumor
22
2026
3542
0.830
Why?
Transforming Growth Factor beta
8
2026
474
0.740
Why?
Myeloid-Derived Suppressor Cells
1
2023
76
0.740
Why?
Tumor Suppressor Protein p53
1
2025
534
0.680
Why?
Mammary Glands, Animal
5
2015
128
0.670
Why?
Precancerous Conditions
1
2022
166
0.640
Why?
Proto-Oncogene Proteins c-akt
9
2017
440
0.610
Why?
Signal Transduction
18
2026
5216
0.580
Why?
ErbB Receptors
4
2022
635
0.530
Why?
Mammary Neoplasms, Animal
3
2015
35
0.520
Why?
Mice
30
2026
18329
0.470
Why?
Mice, Nude
11
2020
679
0.470
Why?
Paracrine Communication
1
2015
67
0.430
Why?
Wound Healing
3
2026
355
0.420
Why?
Tumor Microenvironment
7
2026
734
0.420
Why?
Extracellular Signal-Regulated MAP Kinases
1
2015
174
0.420
Why?
Animals
38
2026
38030
0.410
Why?
Protein Kinase Inhibitors
3
2017
981
0.380
Why?
Phosphatidylinositol 3-Kinase
2
2023
25
0.380
Why?
Disease Models, Animal
9
2025
4560
0.350
Why?
Glucose Transporter Type 1
1
2011
48
0.340
Why?
Radiotherapy, Intensity-Modulated
2
2025
142
0.330
Why?
B7-H1 Antigen
2
2024
244
0.330
Why?
Stomatitis
2
2021
15
0.320
Why?
Mucositis
2
2021
20
0.310
Why?
Cell Proliferation
8
2020
2507
0.310
Why?
Mice, Transgenic
11
2025
2188
0.310
Why?
Smad4 Protein
2
2020
34
0.300
Why?
Apoptosis
4
2020
2440
0.300
Why?
Keratinocytes
4
2026
249
0.290
Why?
Up-Regulation
3
2024
847
0.280
Why?
Fats
1
2008
13
0.270
Why?
Mutation
3
2015
4075
0.270
Why?
Radiation Injuries, Experimental
2
2025
20
0.260
Why?
Neoplastic Stem Cells
2
2022
409
0.250
Why?
Drug Resistance, Neoplasm
7
2017
881
0.250
Why?
Reactive Oxygen Species
1
2009
611
0.250
Why?
Glucose
2
2011
1048
0.240
Why?
Integrin beta1
1
2026
33
0.240
Why?
rac1 GTP-Binding Protein
2
2017
56
0.240
Why?
Xenograft Model Antitumor Assays
6
2020
934
0.230
Why?
Tumor Escape
1
2026
49
0.230
Why?
Genes, p53
2
2020
67
0.230
Why?
Metaplasia
1
2025
57
0.230
Why?
Radiodermatitis
1
2025
11
0.230
Why?
Epidermis
1
2026
156
0.220
Why?
Female
30
2026
78844
0.220
Why?
Lung Neoplasms
4
2026
2664
0.220
Why?
Cell Plasticity
1
2025
37
0.220
Why?
Diabetes Mellitus, Experimental
1
2026
199
0.210
Why?
Cachexia
1
2025
74
0.210
Why?
Antineoplastic Combined Chemotherapy Protocols
4
2020
1963
0.210
Why?
Carcinogenesis
2
2023
228
0.200
Why?
Phosphatidylinositols
1
2023
57
0.200
Why?
Dermatitis
1
2023
20
0.190
Why?
Receptors, Interleukin
1
2023
43
0.190
Why?
Carcinogens
1
2023
123
0.190
Why?
Phosphoprotein Phosphatases
1
2002
66
0.190
Why?
Humans
36
2026
145474
0.180
Why?
Phosphorylation
6
2015
1707
0.180
Why?
Glycerol
1
2002
90
0.180
Why?
Mechanistic Target of Rapamycin Complex 2
3
2017
62
0.180
Why?
Antineoplastic Agents
4
2017
2214
0.180
Why?
Immunologic Memory
1
2024
368
0.180
Why?
Laminin
1
2022
72
0.180
Why?
Psoriasis
1
2023
115
0.180
Why?
Receptors, Fibroblast Growth Factor
1
2022
70
0.180
Why?
Biological Products
1
2025
257
0.170
Why?
Neoplasms, Experimental
2
2020
167
0.170
Why?
Gene Expression Regulation, Neoplastic
5
2018
1443
0.160
Why?
Cancer-Associated Fibroblasts
1
2020
23
0.160
Why?
Receptor, Fibroblast Growth Factor, Type 1
2
2017
58
0.160
Why?
Radiation Injuries
1
2021
149
0.160
Why?
Hyaluronan Receptors
1
2020
104
0.160
Why?
Cell Movement
3
2018
959
0.140
Why?
Tumor Burden
3
2018
325
0.140
Why?
Receptor, EphB3
1
2018
4
0.140
Why?
CD8-Positive T-Lymphocytes
1
2024
919
0.140
Why?
Poly(ADP-ribose) Polymerase Inhibitors
1
2020
133
0.140
Why?
Estradiol
2
2013
515
0.140
Why?
Estrogen Receptor Modulators
2
2017
14
0.130
Why?
Protein Binding
2
2015
2238
0.130
Why?
Multiprotein Complexes
2
2016
172
0.130
Why?
Morpholines
1
2018
130
0.130
Why?
Aminopyridines
1
2018
129
0.130
Why?
Smokers
1
2018
138
0.130
Why?
Mice, Inbred C57BL
6
2026
5983
0.130
Why?
Immunoblotting
2
2011
295
0.130
Why?
Disease-Free Survival
2
2015
767
0.120
Why?
Neoplasm Transplantation
2
2014
246
0.120
Why?
Estrogen Receptor alpha
1
2017
151
0.120
Why?
Quinazolines
2
2017
266
0.120
Why?
TOR Serine-Threonine Kinases
2
2016
454
0.110
Why?
Down-Regulation
2
2015
618
0.110
Why?
Extracellular Matrix
2
2022
562
0.110
Why?
Hyperplasia
2
2013
177
0.110
Why?
Amphiregulin
1
2015
27
0.110
Why?
Protein Kinase C-alpha
1
2015
37
0.110
Why?
Neuropeptides
1
2015
75
0.110
Why?
Carrier Proteins
2
2016
728
0.110
Why?
Cell Adhesion
2
2022
451
0.110
Why?
Antibodies, Neutralizing
1
2017
340
0.110
Why?
Epidermal Growth Factor
1
2015
162
0.110
Why?
Bone Morphogenetic Proteins
1
2015
143
0.110
Why?
Receptors, Estrogen
1
2017
401
0.110
Why?
Morphogenesis
1
2015
172
0.100
Why?
Neoplasm Metastasis
3
2026
688
0.100
Why?
Gene Expression
3
2014
1476
0.100
Why?
Carcinoma, Non-Small-Cell Lung
1
2023
1189
0.100
Why?
Quinolines
1
2015
190
0.100
Why?
Genes, erbB-2
1
2013
32
0.100
Why?
Transcriptome
3
2018
1038
0.100
Why?
Skin
3
2025
753
0.100
Why?
Autophagy
1
2015
291
0.100
Why?
Receptors, Calcitriol
2
2010
55
0.100
Why?
Chromatography, Liquid
1
2015
450
0.100
Why?
Immunotherapy
1
2018
666
0.100
Why?
Cell Transformation, Neoplastic
2
2012
337
0.090
Why?
Heterografts
3
2018
143
0.090
Why?
Mammary Tumor Virus, Mouse
2
2011
42
0.090
Why?
Rapamycin-Insensitive Companion of mTOR Protein
3
2017
27
0.090
Why?
Immunohistochemistry
2
2018
1716
0.090
Why?
Dogs
2
2025
458
0.090
Why?
Cell Line
3
2015
2823
0.090
Why?
Antineoplastic Agents, Hormonal
1
2013
193
0.090
Why?
Neoplasm Proteins
1
2015
441
0.090
Why?
NF-kappa B
2
2026
666
0.090
Why?
Tandem Mass Spectrometry
1
2015
572
0.090
Why?
Gene Amplification
3
2017
118
0.090
Why?
Inflammation
2
2023
2878
0.080
Why?
Macrophages
1
2019
1507
0.080
Why?
Pyrazoles
1
2015
517
0.080
Why?
Skin Neoplasms
1
2018
849
0.080
Why?
Mutation, Missense
1
2013
335
0.080
Why?
Mice, Inbred BALB C
3
2023
1261
0.080
Why?
Alkylating Agents
1
2010
24
0.080
Why?
Transcription, Genetic
1
2017
1454
0.080
Why?
T-Lymphocytes
1
2019
1996
0.080
Why?
Triple Negative Breast Neoplasms
1
2013
218
0.080
Why?
Calcitriol
1
2010
57
0.080
Why?
Tumor Cells, Cultured
3
2020
886
0.080
Why?
BRCA1 Protein
1
2010
82
0.070
Why?
Neoplasm Staging
3
2018
1471
0.070
Why?
Ovarian Neoplasms
1
2015
595
0.070
Why?
Cetuximab
2
2020
111
0.070
Why?
Prognosis
4
2020
4316
0.070
Why?
Phthalazines
2
2020
63
0.070
Why?
Polymerase Chain Reaction
1
2011
1041
0.070
Why?
Proteomics
1
2015
1188
0.070
Why?
Male
7
2026
72842
0.070
Why?
L-Lactate Dehydrogenase
1
2008
112
0.070
Why?
Cell Death
1
2009
382
0.070
Why?
Insulin-Like Growth Factor I
1
2010
317
0.060
Why?
Calcifediol
1
2007
31
0.060
Why?
Vitamin D
1
2010
403
0.060
Why?
Mitogen-Activated Protein Kinases
2
2011
288
0.060
Why?
Models, Biological
2
2018
1764
0.060
Why?
Enzyme Activation
1
2008
762
0.060
Why?
Oxidative Phosphorylation
1
2008
209
0.060
Why?
Gene Expression Profiling
1
2013
1767
0.060
Why?
Carcinoma
1
2008
225
0.060
Why?
Piperazines
2
2020
375
0.060
Why?
MAP Kinase Signaling System
2
2011
307
0.060
Why?
Kidney Neoplasms
1
2010
413
0.060
Why?
Cell Survival
3
2015
1100
0.060
Why?
Antibodies, Monoclonal
1
2013
1505
0.060
Why?
Molecular Targeted Therapy
2
2020
439
0.060
Why?
Phenotype
3
2023
3155
0.060
Why?
Glycolysis
1
2008
340
0.060
Why?
Blotting, Western
3
2016
1179
0.060
Why?
Magnetic Resonance Spectroscopy
1
2008
627
0.060
Why?
SKP Cullin F-Box Protein Ligases
1
2025
15
0.060
Why?
Tripartite Motif Proteins
1
2025
39
0.060
Why?
Administration, Cutaneous
1
2025
127
0.060
Why?
Kaplan-Meier Estimate
2
2018
969
0.050
Why?
Muscular Atrophy
1
2025
87
0.050
Why?
Lipid Metabolism
1
2008
529
0.050
Why?
Fluorescent Antibody Technique
2
2018
365
0.050
Why?
Muscle Fibers, Skeletal
1
2025
212
0.050
Why?
MCF-7 Cells
2
2014
133
0.050
Why?
Ubiquitin-Protein Ligases
1
2025
192
0.050
Why?
Muscle Proteins
1
2025
242
0.050
Why?
Swine
1
2026
825
0.050
Why?
Histocompatibility Antigens Class I
1
2024
202
0.050
Why?
Phosphothreonine
1
2002
6
0.050
Why?
Nitric Oxide Synthase Type II
1
2023
162
0.050
Why?
Protein Phosphatase 2C
1
2002
15
0.050
Why?
Osmosis
1
2002
22
0.050
Why?
Nuclear Proteins
1
2008
740
0.050
Why?
Glutathione Transferase
1
2002
92
0.050
Why?
Protein Transport
2
2017
442
0.050
Why?
Myeloid Cells
1
2023
147
0.040
Why?
Cell Cycle Proteins
2
2020
630
0.040
Why?
Catalytic Domain
1
2002
234
0.040
Why?
Gene Products, tat
1
2021
22
0.040
Why?
Luminescent Proteins
1
2002
186
0.040
Why?
Plasmids
1
2002
373
0.040
Why?
Biomarkers, Tumor
2
2019
1321
0.040
Why?
Microscopy, Fluorescence
1
2002
408
0.040
Why?
Green Fluorescent Proteins
1
2002
407
0.040
Why?
Mitochondria
1
2008
992
0.040
Why?
Epithelium
2
2012
310
0.040
Why?
Zinc Finger E-box-Binding Homeobox 1
1
2020
21
0.040
Why?
Disease Progression
2
2020
2864
0.040
Why?
Protein Structure, Tertiary
1
2002
855
0.040
Why?
Feedback, Physiological
1
2020
80
0.040
Why?
Neutrophils
1
2026
1124
0.040
Why?
SOXB1 Transcription Factors
1
2020
67
0.040
Why?
Prostatic Neoplasms
1
2007
978
0.040
Why?
Recombinant Fusion Proteins
1
2002
666
0.040
Why?
Temperature
1
2002
633
0.040
Why?
Transcription Factors
1
2008
1734
0.040
Why?
Epithelial Cells
2
2019
1131
0.040
Why?
Clodronic Acid
1
2019
19
0.040
Why?
Kinetics
1
2002
1567
0.040
Why?
Lymphocytes, Tumor-Infiltrating
1
2020
153
0.040
Why?
Genes, Tumor Suppressor
1
2019
85
0.040
Why?
Saccharomyces cerevisiae Proteins
1
2002
414
0.040
Why?
RNA, Neoplasm
1
2018
83
0.040
Why?
Mice, Inbred NOD
1
2020
613
0.030
Why?
Guinea Pigs
1
2018
159
0.030
Why?
Nitric Oxide
1
2023
892
0.030
Why?
Radiotherapy, Image-Guided
1
2018
39
0.030
Why?
Dose-Response Relationship, Drug
1
2002
2028
0.030
Why?
Pregnancy
1
2011
7202
0.030
Why?
Hyaluronic Acid
1
2020
226
0.030
Why?
Saccharomyces cerevisiae
1
2002
573
0.030
Why?
Fibrosis
1
2020
559
0.030
Why?
Maytansine
1
2017
18
0.030
Why?
rho Guanine Nucleotide Dissociation Inhibitor beta
1
2017
4
0.030
Why?
Monocytes
1
2020
539
0.030
Why?
Adaptor Proteins, Signal Transducing
1
2020
425
0.030
Why?
Cyclin D1
1
2017
64
0.030
Why?
DNA Mutational Analysis
1
2018
407
0.030
Why?
Cell Cycle
2
2010
598
0.030
Why?
Cyclin-Dependent Kinase 4
1
2017
53
0.030
Why?
Cyclin-Dependent Kinase 6
1
2017
49
0.030
Why?
Trastuzumab
1
2017
118
0.030
Why?
DNA Repair
1
2019
254
0.030
Why?
Time Factors
2
2010
7123
0.030
Why?
RNA Interference
1
2018
475
0.030
Why?
Tissue Array Analysis
1
2016
49
0.030
Why?
Fibroblast Growth Factors
1
2017
188
0.030
Why?
Bone Morphogenetic Protein Receptors
1
2015
5
0.030
Why?
In Vitro Techniques
1
2017
1048
0.030
Why?
Ligands
1
2017
665
0.030
Why?
DNA Damage
1
2018
437
0.030
Why?
Combined Modality Therapy
1
2018
1266
0.030
Why?
Organ Culture Techniques
1
2015
154
0.030
Why?
Muscle, Skeletal
1
2025
1789
0.030
Why?
Spheroids, Cellular
1
2015
74
0.030
Why?
c-Mer Tyrosine Kinase
1
2014
39
0.030
Why?
Mechanistic Target of Rapamycin Complex 1
1
2015
138
0.030
Why?
Biomarkers
2
2018
4295
0.030
Why?
Coculture Techniques
1
2014
247
0.030
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2013
39
0.030
Why?
Genes, myc
1
2013
51
0.030
Why?
Neoplasm Invasiveness
1
2015
506
0.020
Why?
Ki-67 Antigen
1
2013
117
0.020
Why?
Cisplatin
1
2015
345
0.020
Why?
Neoplasm, Residual
1
2013
143
0.020
Why?
Gene Dosage
1
2013
145
0.020
Why?
DNA Copy Number Variations
1
2013
184
0.020
Why?
Phagocytosis
1
2014
296
0.020
Why?
Drug Synergism
1
2013
354
0.020
Why?
Receptor Protein-Tyrosine Kinases
1
2014
231
0.020
Why?
Cluster Analysis
1
2013
500
0.020
Why?
Cell Line, Transformed
1
2011
138
0.020
Why?
Epithelial-Mesenchymal Transition
1
2013
219
0.020
Why?
Oligonucleotide Array Sequence Analysis
1
2013
749
0.020
Why?
Postpartum Period
1
2014
373
0.020
Why?
Antibodies, Monoclonal, Humanized
1
2017
992
0.020
Why?
Cell Growth Processes
1
2011
48
0.020
Why?
Proto-Oncogene Proteins
1
2014
624
0.020
Why?
Cyclin A
1
2010
17
0.020
Why?
Alkylation
1
2010
27
0.020
Why?
Treatment Outcome
2
2018
11772
0.020
Why?
Oligonucleotides, Antisense
1
2011
118
0.020
Why?
Neoadjuvant Therapy
1
2013
465
0.020
Why?
Immunoenzyme Techniques
1
2010
200
0.020
Why?
Survival Analysis
1
2013
1374
0.020
Why?
Receptor, IGF Type 1
1
2010
64
0.020
Why?
Caspases
1
2010
233
0.020
Why?
Immunoprecipitation
1
2010
148
0.020
Why?
Quality of Life
1
2022
3204
0.020
Why?
Mitogen-Activated Protein Kinase 1
1
2010
171
0.020
Why?
Proteasome Endopeptidase Complex
1
2010
155
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2010
977
0.020
Why?
Interleukin-6
1
2011
776
0.020
Why?
Estrogens
1
2010
367
0.020
Why?
Cytokines
1
2014
2067
0.020
Why?
Mass Spectrometry
1
2010
730
0.020
Why?
Recombinant Proteins
1
2010
1368
0.020
Why?
Biological Transport
1
2007
424
0.010
Why?
Adenocarcinoma
1
2012
925
0.010
Why?
Cells, Cultured
1
2010
4148
0.010
Why?
Aged
1
2018
26153
0.010
Why?
Middle Aged
1
2018
36215
0.010
Why?
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