 Calcitriol
"Calcitriol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The physiologically active form of vitamin D. It is formed primarily in the kidney by enzymatic hydroxylation of 25-hydroxycholecalciferol (CALCIFEDIOL). Its production is stimulated by low blood calcium levels and parathyroid hormone. Calcitriol increases intestinal absorption of calcium and phosphorus, and in concert with parathyroid hormone increases bone resorption.
| Descriptor ID |
D002117
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| MeSH Number(s) |
D04.210.500.247.222.159.478.387.300 D04.210.500.247.808.146.478.387.300 D04.210.500.812.768.196.478.387.300 D10.570.938.146.478.387.300
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| Concept/Terms |
Calcitriol- Calcitriol
- 1 alpha,25-Dihydroxyvitamin D3
- 1 alpha,25 Dihydroxyvitamin D3
- D3, 1 alpha,25-Dihydroxyvitamin
- alpha,25-Dihydroxyvitamin D3, 1
- 1,25-Dihydroxyvitamin D3
- 1,25 Dihydroxyvitamin D3
- D3, 1,25-Dihydroxyvitamin
- 1 alpha,25-Dihydroxycholecalciferol
- 1 alpha,25 Dihydroxycholecalciferol
- 1,25-Dihydroxycholecalciferol
- 1,25 Dihydroxycholecalciferol
20-epi-1alpha,25-dihydroxycholecaliferol- 20-epi-1alpha,25-dihydroxycholecaliferol
- 20 epi 1alpha,25 dihydroxycholecaliferol
- 1,25-dihydroxy-20-epi-Vitamin D3
- 1,25 dihydroxy 20 epi Vitamin D3
- D3, 1,25-dihydroxy-20-epi-Vitamin
- 1,25(OH)2-20epi-D3
- 1 alpha, 25-dihydroxy-20-epi-Vitamin D3
- 1 alpha, 25 dihydroxy 20 epi Vitamin D3
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Below are MeSH descriptors whose meaning is more general than "Calcitriol".
Below are MeSH descriptors whose meaning is more specific than "Calcitriol".
This graph shows the total number of publications written about "Calcitriol" by people in this website by year, and whether "Calcitriol" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 | | 1996 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 2 | 1 | 3 | | 2004 | 1 | 0 | 1 | | 2006 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 2 | 0 | 2 | | 2011 | 2 | 0 | 2 | | 2013 | 1 | 0 | 1 | | 2014 | 5 | 1 | 6 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Calcitriol" by people in Profiles.
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da Silva Teixeira S, Harrison K, Uzodike M, Rajapakshe K, Coarfa C, He Y, Xu Y, Sisley S. Vitamin D actions in neurons require the PI3K pathway for both enhancing insulin signaling and rapid depolarizing effects. J Steroid Biochem Mol Biol. 2020 06; 200:105690.
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Zelnick LR, de Boer IH, Kestenbaum BR, Chonchol M, Kendrick J. Comparative Effects of Cholecalciferol and Calcitriol on Circulating Markers of CKD Mineral Bone Disorder: A Randomized Clinical Trial. Clin J Am Soc Nephrol. 2018 06 07; 13(6):927-928.
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Kendrick J, Andrews E, You Z, Moreau K, Nowak KL, Farmer-Bailey H, Seals DR, Chonchol M. Cholecalciferol, Calcitriol, and Vascular Function in CKD: A Randomized, Double-Blind Trial. Clin J Am Soc Nephrol. 2017 Sep 07; 12(9):1438-1446.
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Gari HH, DeGala GD, Ray R, Lucia MS, Lambert JR. PRL-3 engages the focal adhesion pathway in triple-negative breast cancer cells to alter actin structure and substrate adhesion properties critical for cell migration and invasion. Cancer Lett. 2016 10 01; 380(2):505-512.
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Gari HH, Gearheart CM, Fosmire S, DeGala GD, Fan Z, Torkko KC, Edgerton SM, Lucia MS, Ray R, Thor AD, Porter CC, Lambert JR. Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers. Oncotarget. 2016 Mar 29; 7(13):15757-71.
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Schedel M, Jia Y, Michel S, Takeda K, Domenico J, Joetham A, Ning F, Strand M, Han J, Wang M, Lucas JJ, Vogelberg C, Kabesch M, O'Connor BP, Gelfand EW. 1,25D3 prevents CD8(+)Tc2 skewing and asthma development through VDR binding changes to the Cyp11a1 promoter. Nat Commun. 2016 Jan 11; 7:10213.
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Leaf DE, Raed A, Donnino MW, Ginde AA, Waikar SS. Reply: active and native vitamin D in critical illness. Am J Respir Crit Care Med. 2014 Nov 15; 190(10):1194-6.
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Leaf DE, Raed A, Donnino MW, Ginde AA, Waikar SS. Randomized controlled trial of calcitriol in severe sepsis. Am J Respir Crit Care Med. 2014 Sep 01; 190(5):533-41.
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Weeres MA, Robien K, Ahn YO, Neulen ML, Bergerson R, Miller JS, Verneris MR. The effects of 1,25-dihydroxyvitamin D3 on in vitro human NK cell development from hematopoietic stem cells. J Immunol. 2014 Oct 01; 193(7):3456-62.
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Swanson CM, Nielson CM, Shrestha S, Lee CG, Barrett-Connor E, Jans I, Cauley JA, Boonen S, Bouillon R, Vanderschueren D, Orwoll ES. Higher 25(OH)D2 is associated with lower 25(OH)D3 and 1,25(OH)2D3. J Clin Endocrinol Metab. 2014 Aug; 99(8):2736-44.
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