 rho Guanine Nucleotide Dissociation Inhibitor beta
"rho Guanine Nucleotide Dissociation Inhibitor beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rho GDP-dissociation inhibitor subtype that is highly expressed in hematopoietic cells and in LYMPHOCYTES. The expression of this subtype is associated with the regulation of CELL PROLIFERATION; TUMORIGENESIS; and APOPTOSIS.
| Descriptor ID |
D062949
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| MeSH Number(s) |
D12.644.360.325.225.500.200 D12.776.476.325.225.500.200 D23.050.301.500.600.850 D23.050.705.552.600.700
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| Concept/Terms |
rho Guanine Nucleotide Dissociation Inhibitor beta- rho Guanine Nucleotide Dissociation Inhibitor beta
- rho GDP-Dissociation Inhibitor beta
- rho GDP Dissociation Inhibitor beta
- rhoGDIbeta
- rho GDP-Dissociation Inhibitor 2
- rho GDP Dissociation Inhibitor 2
- rhoGDI2
- rho Guanine Nucleotide Dissociation Inhibitor 2
- rho GDIbeta
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Below are MeSH descriptors whose meaning is more general than "rho Guanine Nucleotide Dissociation Inhibitor beta".
Below are MeSH descriptors whose meaning is more specific than "rho Guanine Nucleotide Dissociation Inhibitor beta".
This graph shows the total number of publications written about "rho Guanine Nucleotide Dissociation Inhibitor beta" by people in this website by year, and whether "rho Guanine Nucleotide Dissociation Inhibitor beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "rho Guanine Nucleotide Dissociation Inhibitor beta" by people in Profiles.
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Morrison Joly M, Williams MM, Hicks DJ, Jones B, Sanchez V, Young CD, Sarbassov DD, Muller WJ, Brantley-Sieders D, Cook RS. Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis. Breast Cancer Res. 2017 Jun 30; 19(1):74.
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Ahmed M, Sottnik JL, Dancik GM, Sahu D, Hansel DE, Theodorescu D, Schwartz MA. An Osteopontin/CD44 Axis in RhoGDI2-Mediated Metastasis Suppression. Cancer Cell. 2016 09 12; 30(3):432-443.
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Griner EM, Dancik GM, Costello JC, Owens C, Guin S, Edwards MG, Brautigan DL, Theodorescu D. RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer. Mol Cancer Res. 2015 Mar; 13(3):483-92.
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Griner EM, Churchill ME, Brautigan DL, Theodorescu D. PKCa phosphorylation of RhoGDI2 at Ser31 disrupts interactions with Rac1 and decreases GDI activity. Oncogene. 2013 Feb 21; 32(8):1010-7.
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