 Cancer-Associated Fibroblasts
"Cancer-Associated Fibroblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Subpopulation of heterogeneous fibroblasts within the TUMOR MICROENVIRONMENT that support NEOPLASTIC CELL TRANSFORMATION and NEOPLASTIC PROCESSES.
| Descriptor ID |
D000072645
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| MeSH Number(s) |
A11.329.228.105
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| Concept/Terms |
Cancer-Associated Fibroblasts- Cancer-Associated Fibroblasts
- Cancer-Associated Fibroblast
- Fibroblast, Cancer-Associated
- Fibroblasts, Cancer-Associated
- Cancer Associated Fibroblasts
- Cancer Associated Fibroblast
- Fibroblast, Cancer Associated
- Fibroblasts, Cancer Associated
- Tumor-Associated Fibroblasts
- Fibroblast, Tumor-Associated
- Fibroblasts, Tumor-Associated
- Tumor Associated Fibroblasts
- Tumor-Associated Fibroblast
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Below are MeSH descriptors whose meaning is more general than "Cancer-Associated Fibroblasts".
Below are MeSH descriptors whose meaning is more specific than "Cancer-Associated Fibroblasts".
This graph shows the total number of publications written about "Cancer-Associated Fibroblasts" by people in this website by year, and whether "Cancer-Associated Fibroblasts" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2024 | 1 | 1 | 2 | | 2025 | 3 | 1 | 4 |
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Below are the most recent publications written about "Cancer-Associated Fibroblasts" by people in Profiles.
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Prawira A, Xu H, Mei Y, Leow WQ, Nasir NJM, Reolo MJ, Otsuka M, Rahbari M, Chen Z, Weerasooriya M, Abdullah LB, Wu J, Hazirah SN, Wasser M, Chung A, Goh BK, Chow PK, Albani S, Lee J, Lim TKH, Zhai W, Dan YY, Goh GB, Heikenwälder MF, Zhang Y, Dasgupta R, Tai WMD, Liu H, Chen J, Chew V. Targeting Treg-fibroblast interaction to enhance immunotherapy in steatotic liver disease-related hepatocellular carcinoma. Gut. 2025 Dec 05; 75(1):105-118.
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Klosowski ML, Cronise KE, Palmer EP, McAuliffe K, Stratton C, Sparks K, Malmstrom KT, Knott-Byars G, Zhou Q, Esquer H, LaBarbera DV, Regan DP. Breast cancer cell coculture induces normal lung fibroblast transition to CAFs, promoting tumor cell dormancy and therapy resistance. Proc Natl Acad Sci U S A. 2025 Nov 25; 122(47):e2423894122.
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Nishida-Aoki N, Zhu S, Chan M, Kang Y, Fujita M, Jiang X, McCabe M, Vaz JM, Davidson NE, Ghajar CM, Hansen K, Welm AL, Pillarisetty VG, Gujral TS. Drug screening in 3D microtumors reveals DDR1/2-MAPK12-GLI1 as a vulnerability in cancer-associated fibroblasts. Cell Rep Med. 2025 Oct 21; 6(10):102357.
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Le PN, Keysar SB, Miller B, Morton JJ, Chimed TS, Alzofon N, Nieto C, Davies KD, Thomas CM, Weaver AN, Jimeno A. Improved Methods for the Stable Generation of Human Papillomavirus-Driven Head and Neck Cancer Cell Lines. Mol Carcinog. 2025 Nov; 64(11):1813-1822.
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Brechbuhl HM, Sartorius CA. Sticky Business: Progesterone Receptors Mediate Cancer Associated Fibroblast and Breast Cancer Cell Interaction. Endocrinology. 2024 Aug 27; 165(10).
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Desai P, Takahashi N, Kumar R, Nichols S, Malin J, Hunt A, Schultz C, Cao Y, Tillo D, Nousome D, Chauhan L, Sciuto L, Jordan K, Rajapakse V, Tandon M, Lissa D, Zhang Y, Kumar S, Pongor L, Singh A, Schroder B, Sharma AK, Chang T, Vilimas R, Pinkiert D, Graham C, Butcher D, Warner A, Sebastian R, Mahon M, Baker K, Cheng J, Berger A, Lake R, Abel M, Krishnamurthy M, Chrisafis G, Fitzgerald P, Nirula M, Goyal S, Atkinson D, Bateman NW, Abulez T, Nair G, Apolo A, Guha U, Karim B, El Meskini R, Ohler ZW, Jolly MK, Schaffer A, Ruppin E, Kleiner D, Miettinen M, Brown GT, Hewitt S, Conrads T, Thomas A. Microenvironment shapes small-cell lung cancer neuroendocrine states and presents therapeutic opportunities. Cell Rep Med. 2024 Jun 18; 5(6):101610.
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Yu J, Piazza A, Sparks S, Hind LE, Niles DJ, Ingram PN, Huang W, Ricke WA, Jarrard DF, Huttenlocher A, Basu H, Beebe DJ. A reconfigurable microscale assay enables insights into cancer-associated fibroblast modulation of immune cell recruitment. Integr Biol (Camb). 2021 04 20; 13(4):87-97.
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Shi X, Young CD, Zhou H, Wang X. Transforming Growth Factor-ß Signaling in Fibrotic Diseases and Cancer-Associated Fibroblasts. Biomolecules. 2020 12 12; 10(12).
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Piper M, Mueller AC, Karam SD. The interplay between cancer associated fibroblasts and immune cells in the context of radiation therapy. Mol Carcinog. 2020 07; 59(7):754-765.
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Darragh LB, Oweida AJ, Karam SD. Overcoming Resistance to Combination Radiation-Immunotherapy: A Focus on Contributing Pathways Within the Tumor Microenvironment. Front Immunol. 2018; 9:3154.
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