 SKP Cullin F-Box Protein Ligases
"SKP Cullin F-Box Protein Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subset of ubiquitin protein ligases that are formed by the association of a SKP DOMAIN PROTEIN, a CULLIN DOMAIN PROTEIN and a F-BOX DOMAIN PROTEIN.
| Descriptor ID |
D044843
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| MeSH Number(s) |
D08.811.464.938.750.750
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| Concept/Terms |
SKP1-Cullin Ubiquitin Ligases- SKP1-Cullin Ubiquitin Ligases
- Ligases, SKP1-Cullin Ubiquitin
- SKP1 Cullin Ubiquitin Ligases
- Ubiquitin Ligases, SKP1-Cullin
- Skp1-Cullin-1-F-box Ubiquitin Ligase
- Ligase, Skp1-Cullin-1-F-box Ubiquitin
- Skp1 Cullin 1 F box Ubiquitin Ligase
- Ubiquitin Ligase, Skp1-Cullin-1-F-box
- Skp1-Cullin-F-Box Proteins
- Skp1 Cullin F Box Proteins
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Below are MeSH descriptors whose meaning is more general than "SKP Cullin F-Box Protein Ligases".
Below are MeSH descriptors whose meaning is more specific than "SKP Cullin F-Box Protein Ligases".
This graph shows the total number of publications written about "SKP Cullin F-Box Protein Ligases" by people in this website by year, and whether "SKP Cullin F-Box Protein Ligases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2013 | 1 | 2 | 3 | | 2014 | 0 | 1 | 1 | | 2021 | 1 | 0 | 1 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "SKP Cullin F-Box Protein Ligases" by people in Profiles.
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Livingston PD, Labbate Bonaldo AL, Jamnick NA, Weinzierl NM, Gammon CJ, Callaway CS, Lee S, Gao B, Goodspeed A, Carvalho RF, Young CD, Orlicky DJ, Adams DJ, Novinger LJ, Bonetto A. B0092 tumor-bearing mice are a new model for the study of cachexia in head and neck cancer. Am J Physiol Cell Physiol. 2025 Aug 01; 329(2):C646-C658.
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Mills CA, Wang X, Bhatt DP, Grimsrud PA, Matson JP, Lahiri D, Burke DJ, Cook JG, Hirschey MD, Emanuele MJ. Sirtuin 5 Is Regulated by the SCFCyclin F Ubiquitin Ligase and Is Involved in Cell Cycle Control. Mol Cell Biol. 2021 01 25; 41(2).
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Sheikh MO, Thieker D, Chalmers G, Schafer CM, Ishihara M, Azadi P, Woods RJ, Glushka JN, Bendiak B, Prestegard JH, West CM. O2 sensing-associated glycosylation exposes the F-box-combining site of the Dictyostelium Skp1 subunit in E3 ubiquitin ligases. J Biol Chem. 2017 11 17; 292(46):18897-18915.
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Honarpour N, Rose CM, Brumbaugh J, Anderson J, Graham RL, Sweredoski MJ, Hess S, Coon JJ, Deshaies RJ. F-box protein FBXL16 binds PP2A-B55a and regulates differentiation of embryonic stem cells along the FLK1+ lineage. Mol Cell Proteomics. 2014 Mar; 13(3):780-91.
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Hanson AM, Harrison BC, Young MH, Stodieck LS, Ferguson VL. Longitudinal characterization of functional, morphologic, and biochemical adaptations in mouse skeletal muscle with hindlimb suspension. Muscle Nerve. 2013 Sep; 48(3):393-402.
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Bonetto A, Penna F, Aversa Z, Mercantini P, Baccino FM, Costelli P, Ziparo V, Lucia S, Rossi Fanelli F, Muscaritoli M. Early changes of muscle insulin-like growth factor-1 and myostatin gene expression in gastric cancer patients. Muscle Nerve. 2013 Sep; 48(3):387-92.
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Davis MA, Larimore EA, Fissel BM, Swanger J, Taatjes DJ, Clurman BE. The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator. Genes Dev. 2013 Jan 15; 27(2):151-6.
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van der Wel H, Johnson JM, Xu Y, Karunaratne CV, Wilson KD, Vohra Y, Boons GJ, Taylor CM, Bendiak B, West CM. Requirements for Skp1 processing by cytosolic prolyl 4(trans)-hydroxylase and a-N-acetylglucosaminyltransferase enzymes involved in O2 signaling in dictyostelium. Biochemistry. 2011 Mar 15; 50(10):1700-13.
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Allen DL, Cleary AS, Lindsay SF, Loh AS, Reed JM. Myostatin expression is increased by food deprivation in a muscle-specific manner and contributes to muscle atrophy during prolonged food deprivation in mice. J Appl Physiol (1985). 2010 Sep; 109(3):692-701.
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Killian DJ, Harvey E, Johnson P, Otori M, Mitani S, Xue D. SKR-1, a homolog of Skp1 and a member of the SCF(SEL-10) complex, regulates sex-determination and LIN-12/Notch signaling in C. elegans. Dev Biol. 2008 Oct 15; 322(2):322-31.
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