Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Bruce Appel

Concepts (305)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Zebrafish Proteins
52
2025
286
10.750
Why?
Zebrafish
69
2025
495
10.490
Why?
Oligodendroglia
36
2025
178
10.350
Why?
Myelin Sheath
23
2025
166
8.530
Why?
Spinal Cord
23
2025
370
4.730
Why?
Cell Differentiation
33
2025
1982
4.130
Why?
Axons
16
2025
198
4.060
Why?
Motor Neurons
18
2024
234
3.500
Why?
Gene Expression Regulation, Developmental
31
2025
858
3.040
Why?
Animals, Genetically Modified
31
2025
239
2.530
Why?
Hedgehog Proteins
10
2025
195
2.510
Why?
Nerve Tissue Proteins
18
2021
595
2.450
Why?
Neurogenesis
7
2021
147
2.410
Why?
Neural Stem Cells
6
2025
155
2.350
Why?
Stem Cells
15
2018
592
2.270
Why?
Signal Transduction
26
2025
5077
2.210
Why?
Basic Helix-Loop-Helix Transcription Factors
13
2021
242
1.710
Why?
Receptors, Notch
9
2025
88
1.680
Why?
Embryo, Nonmammalian
20
2021
167
1.670
Why?
Cell Lineage
15
2025
347
1.630
Why?
Cell Movement
10
2015
968
1.590
Why?
Oligodendrocyte Precursor Cells
2
2024
20
1.500
Why?
Body Patterning
13
2014
132
1.460
Why?
Neurons
15
2025
1587
1.430
Why?
Fragile X Mental Retardation Protein
3
2024
50
1.390
Why?
RNA-Binding Proteins
5
2021
423
1.340
Why?
Animals
74
2025
36850
1.340
Why?
Homeodomain Proteins
9
2015
506
1.170
Why?
Central Nervous System
5
2024
258
1.090
Why?
TOR Serine-Threonine Kinases
3
2021
412
1.070
Why?
Schwann Cells
4
2014
34
1.000
Why?
Brain-Derived Neurotrophic Factor
2
2025
131
0.980
Why?
Green Fluorescent Proteins
14
2016
390
0.960
Why?
Receptor, trkB
1
2025
33
0.940
Why?
Receptor, Notch1
5
2012
64
0.920
Why?
Cell Polarity
5
2016
141
0.920
Why?
Docosahexaenoic Acids
1
2024
84
0.870
Why?
Cytoplasmic Dyneins
2
2015
8
0.870
Why?
F-Box Proteins
2
2015
23
0.870
Why?
Oligodendrocyte Transcription Factor 2
11
2025
21
0.830
Why?
Cholesterol
2
2016
410
0.810
Why?
Maternal Nutritional Physiological Phenomena
1
2024
176
0.800
Why?
Mutation
17
2021
3947
0.790
Why?
Ubiquitin-Protein Ligases
2
2015
176
0.780
Why?
Membrane Proteins
8
2008
1163
0.760
Why?
Notochord
5
2006
13
0.740
Why?
Neural Cell Adhesion Molecules
1
2021
32
0.730
Why?
RNA Caps
1
2021
35
0.730
Why?
Rhombencephalon
3
2012
31
0.710
Why?
RNA Transport
1
2021
23
0.700
Why?
Transcription Factors
10
2021
1718
0.690
Why?
Cell Cycle Proteins
4
2015
613
0.680
Why?
3' Untranslated Regions
1
2021
145
0.660
Why?
MicroRNAs
3
2016
692
0.630
Why?
RNA, Messenger
8
2021
2831
0.620
Why?
Proto-Oncogene Proteins c-akt
1
2021
437
0.610
Why?
Carrier Proteins
4
2020
769
0.610
Why?
Protein Biosynthesis
1
2021
430
0.600
Why?
Phagocytosis
1
2020
379
0.580
Why?
Neuroglia
5
2018
173
0.520
Why?
Larva
5
2025
224
0.520
Why?
Myelin Proteins
1
2016
45
0.510
Why?
Cytogenetic Analysis
1
2016
33
0.500
Why?
Neural Crest
3
2014
116
0.500
Why?
Protein Kinase C
2
2025
261
0.490
Why?
Synapses
1
2019
427
0.480
Why?
Brain
4
2018
2664
0.470
Why?
Axonal Transport
1
2015
27
0.470
Why?
Cell Cycle
3
2013
601
0.450
Why?
Trans-Activators
4
2004
398
0.450
Why?
Hydroxymethylglutaryl-CoA Synthase
1
2014
2
0.440
Why?
Phosphatidylinositol 3-Kinases
1
2016
366
0.440
Why?
Pericytes
1
2013
33
0.420
Why?
DNA-Binding Proteins
3
2020
1501
0.410
Why?
SOXE Transcription Factors
2
2025
19
0.390
Why?
Demyelinating Diseases
1
2012
85
0.380
Why?
Peripheral Nerves
2
2012
65
0.370
Why?
Action Potentials
1
2015
493
0.370
Why?
Fragile X Syndrome
2
2024
77
0.360
Why?
Guanine Nucleotide Exchange Factors
1
2011
66
0.350
Why?
In Situ Hybridization
7
2013
316
0.340
Why?
Gene Expression Regulation
3
2017
2605
0.330
Why?
Cell Proliferation
7
2018
2476
0.310
Why?
Isoenzymes
1
2009
304
0.290
Why?
Genes, Reporter
4
2015
268
0.290
Why?
Organogenesis
2
2020
58
0.290
Why?
Adult Stem Cells
1
2007
39
0.280
Why?
Synaptic Vesicles
2
2019
44
0.270
Why?
Wnt Proteins
1
2008
133
0.270
Why?
Exocytosis
2
2019
89
0.270
Why?
Morphogenesis
3
2008
166
0.260
Why?
Cloning, Molecular
7
2008
534
0.260
Why?
Nuclear Proteins
1
2011
712
0.250
Why?
Cerebellum
1
2008
224
0.250
Why?
Cyclin-Dependent Kinase Inhibitor p57
1
2005
4
0.240
Why?
Myelin Basic Protein
3
2025
47
0.240
Why?
Cell Adhesion Molecules
2
2019
181
0.230
Why?
Chondroitin Sulfate Proteoglycans
1
2024
10
0.230
Why?
Morpholinos
2
2016
30
0.230
Why?
Time-Lapse Imaging
2
2015
21
0.230
Why?
Electrical Synapses
1
2024
11
0.220
Why?
Cell Count
2
2016
323
0.220
Why?
F-Box-WD Repeat-Containing Protein 7
2
2015
6
0.220
Why?
Ubiquitin-Protein Ligase Complexes
2
2015
7
0.220
Why?
Proteoglycans
1
2024
107
0.220
Why?
Bromodeoxyuridine
3
2010
80
0.220
Why?
Intracellular Signaling Peptides and Proteins
6
2003
455
0.220
Why?
Glycosyltransferases
1
2003
11
0.210
Why?
Cilia
3
2021
177
0.210
Why?
Retinoids
1
2003
33
0.210
Why?
Nervous System
2
2001
67
0.210
Why?
Models, Biological
6
2019
1773
0.210
Why?
Neuroepithelial Cells
2
2015
4
0.200
Why?
Veratrum Alkaloids
3
2008
19
0.200
Why?
Peripheral Nervous System
1
2003
20
0.200
Why?
Antigens
1
2024
358
0.200
Why?
Receptors, Cell Surface
2
2002
382
0.200
Why?
Amyloid beta-Peptides
1
2025
221
0.190
Why?
Purkinje Cells
1
2003
70
0.190
Why?
Intestines
2
2020
357
0.180
Why?
Microscopy, Confocal
2
2015
324
0.180
Why?
Spatio-Temporal Analysis
1
2021
34
0.180
Why?
Eukaryotic Initiation Factors
1
2021
10
0.180
Why?
Regulatory Sequences, Ribonucleic Acid
1
2021
19
0.180
Why?
Molecular Sequence Data
6
2012
2894
0.170
Why?
Molecular Imaging
1
2021
53
0.170
Why?
Extracellular Matrix
1
2024
528
0.170
Why?
Epigenesis, Genetic
1
2025
657
0.170
Why?
Tissue Distribution
1
2021
330
0.170
Why?
Microscopy, Electron, Transmission
2
2012
150
0.170
Why?
Superior Colliculi
1
2020
40
0.160
Why?
rab GTP-Binding Proteins
1
2020
75
0.160
Why?
Gastrula
3
2006
17
0.160
Why?
Vitamin B 12
2
2017
128
0.160
Why?
Embryonic Stem Cells
2
2010
123
0.150
Why?
Immunohistochemistry
3
2010
1733
0.150
Why?
Female
8
2024
72816
0.150
Why?
Host Cell Factor C1
2
2017
15
0.150
Why?
Interneurons
3
2024
122
0.150
Why?
Single-Cell Analysis
1
2021
311
0.150
Why?
Scoliosis
1
2021
215
0.140
Why?
Sequence Analysis, RNA
1
2021
452
0.140
Why?
Microglia
1
2020
251
0.140
Why?
Mice, Transgenic
2
2020
2163
0.140
Why?
Base Sequence
4
2017
2179
0.130
Why?
Neuronal Plasticity
1
2019
290
0.130
Why?
Phosphotransferases (Alcohol Group Acceptor)
2
2007
45
0.130
Why?
Pregnancy
2
2021
6729
0.120
Why?
Genes, Homeobox
1
1995
50
0.120
Why?
Nerve Fibers, Myelinated
1
2015
46
0.120
Why?
Oligonucleotides, Antisense
2
2008
111
0.120
Why?
Sequence Alignment
2
2012
342
0.120
Why?
Veratridine
1
2015
6
0.120
Why?
Tetrodotoxin
1
2015
39
0.120
Why?
Cell Division
2
2008
796
0.120
Why?
Transcriptome
1
2021
969
0.120
Why?
Potassium Channels, Inwardly Rectifying
1
2015
38
0.110
Why?
Gene Expression
3
2014
1500
0.110
Why?
Sirolimus
1
2016
275
0.110
Why?
Gene Expression Profiling
1
2021
1772
0.110
Why?
Cell Communication
1
2016
315
0.110
Why?
Receptor, Notch3
1
2013
5
0.110
Why?
Repressor Proteins
1
2017
427
0.110
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2013
29
0.110
Why?
Luciferases
1
2013
149
0.100
Why?
Immunoenzyme Techniques
1
2013
219
0.100
Why?
Protein Structure, Tertiary
1
2015
860
0.100
Why?
Colforsin
1
2012
53
0.100
Why?
Cerebral Hemorrhage
1
2013
112
0.100
Why?
Real-Time Polymerase Chain Reaction
1
2013
346
0.100
Why?
Blood-Brain Barrier
1
2013
138
0.100
Why?
Cell Membrane
1
2016
735
0.100
Why?
RNA
2
2012
921
0.100
Why?
Nucleocytoplasmic Transport Proteins
1
2012
7
0.100
Why?
Models, Genetic
2
2012
599
0.100
Why?
Recombinant Fusion Proteins
1
2015
664
0.100
Why?
Arthrogryposis
1
2012
7
0.100
Why?
Ligands
2
2004
661
0.090
Why?
rac GTP-Binding Proteins
1
2011
32
0.090
Why?
Cyclic AMP
1
2012
234
0.090
Why?
rac1 GTP-Binding Protein
1
2011
56
0.090
Why?
Neuropeptides
1
2011
73
0.090
Why?
Phenotype
4
2020
3189
0.090
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2013
975
0.090
Why?
Immunosuppressive Agents
1
2016
889
0.090
Why?
Mutagenesis
1
2012
179
0.090
Why?
Blotting, Western
1
2013
1225
0.090
Why?
Chromosome Mapping
1
2012
523
0.090
Why?
Enzyme Inhibitors
1
2014
839
0.080
Why?
Spinal Nerves
1
2009
5
0.080
Why?
Mice
4
2025
17759
0.080
Why?
Amino Acid Sequence
4
2005
2138
0.080
Why?
Adherens Junctions
1
2009
25
0.080
Why?
Oligodeoxyribonucleotides, Antisense
1
2009
8
0.080
Why?
T-Box Domain Proteins
2
2008
98
0.080
Why?
Caspase 3
1
2010
246
0.080
Why?
Microscopy, Electron
1
2009
432
0.080
Why?
Male
5
2021
67330
0.080
Why?
Sequence Homology, Amino Acid
3
2005
385
0.070
Why?
Calbindin 2
1
2008
8
0.070
Why?
Smoothened Receptor
1
2008
6
0.070
Why?
S100 Calcium Binding Protein G
1
2008
8
0.070
Why?
Zonula Occludens-1 Protein
1
2008
16
0.070
Why?
Oligonucleotide Array Sequence Analysis
1
2010
766
0.070
Why?
Glial Fibrillary Acidic Protein
1
2008
100
0.070
Why?
Time Factors
3
2010
6809
0.070
Why?
Fishes
1
2008
103
0.070
Why?
Morpholines
1
2008
122
0.070
Why?
Developmental Biology
1
2007
22
0.070
Why?
Recombinant Proteins
2
2007
1350
0.070
Why?
Cell Survival
1
2010
1116
0.070
Why?
Fetal Proteins
1
2006
17
0.060
Why?
Muscle Proteins
1
2008
228
0.060
Why?
Flow Cytometry
1
2010
1180
0.060
Why?
Humans
10
2021
136803
0.060
Why?
Intercellular Signaling Peptides and Proteins
1
2008
382
0.060
Why?
Branchial Region
2
2017
36
0.060
Why?
Receptors, G-Protein-Coupled
1
2008
220
0.060
Why?
Craniofacial Abnormalities
2
2017
72
0.060
Why?
Phosphoproteins
1
2008
337
0.060
Why?
Prosencephalon
1
2025
48
0.060
Why?
Microscopy, Fluorescence
1
2006
397
0.060
Why?
Models, Neurological
1
2007
242
0.060
Why?
Hyperkinesis
1
2024
16
0.060
Why?
Connexins
1
2024
48
0.050
Why?
Gap Junctions
1
2024
59
0.050
Why?
Helix-Loop-Helix Motifs
1
2003
12
0.050
Why?
Myocytes, Cardiac
1
2008
523
0.050
Why?
Catalytic Domain
1
2004
207
0.050
Why?
Microinjections
1
2003
86
0.050
Why?
Fibroblast Growth Factors
1
2003
171
0.050
Why?
Age Factors
1
2009
3286
0.050
Why?
Luminescent Proteins
1
2003
178
0.050
Why?
Genetic Vectors
1
2003
317
0.050
Why?
Embryonic and Fetal Development
1
2001
97
0.050
Why?
Mesoderm
1
2002
144
0.040
Why?
Mammals
1
2022
283
0.040
Why?
Microvilli
1
2020
78
0.040
Why?
Hot Temperature
1
2003
391
0.040
Why?
Bone and Bones
1
2022
316
0.040
Why?
Endosomes
1
2020
136
0.040
Why?
Disease Models, Animal
2
2024
4282
0.040
Why?
ELAV-Like Protein 3
1
1998
1
0.040
Why?
Evolution, Molecular
1
2002
488
0.040
Why?
ELAV Proteins
1
1998
14
0.040
Why?
Embryonic Induction
1
1998
31
0.040
Why?
Antigens, Surface
1
1998
153
0.030
Why?
Avian Proteins
1
1996
21
0.030
Why?
Primary Cell Culture
1
2017
171
0.030
Why?
Oncogene Proteins
1
1996
59
0.030
Why?
DNA Primers
1
1995
514
0.030
Why?
Protein Binding
1
2020
2216
0.030
Why?
Oxidoreductases
1
2014
92
0.030
Why?
Gene Knockdown Techniques
1
2014
327
0.030
Why?
Cells, Cultured
2
2011
4192
0.030
Why?
Chondrocytes
1
2014
212
0.020
Why?
Fibroblasts
1
2017
993
0.020
Why?
Rats
2
2011
5639
0.020
Why?
Plasmids
1
2012
360
0.020
Why?
Transcription, Genetic
1
2017
1455
0.020
Why?
SOXD Transcription Factors
1
2010
5
0.020
Why?
Cell Line
2
2007
2838
0.020
Why?
Chick Embryo
1
2010
130
0.020
Why?
Electroporation
1
2010
38
0.020
Why?
Ribonuclease III
1
2010
40
0.020
Why?
Endoribonucleases
1
2010
80
0.020
Why?
DEAD-box RNA Helicases
1
2010
76
0.020
Why?
Embryo, Mammalian
1
2010
232
0.020
Why?
Cell Nucleus
1
2012
617
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2011
429
0.020
Why?
Versicans
1
2008
5
0.020
Why?
Bone Morphogenetic Protein 4
1
2008
43
0.020
Why?
Centrosome
1
2007
71
0.020
Why?
RNA, Small Interfering
1
2010
622
0.020
Why?
Bone Morphogenetic Proteins
1
2008
135
0.020
Why?
Protozoan Proteins
1
2007
82
0.020
Why?
Oligonucleotides
1
2008
148
0.020
Why?
Genotype
1
2012
1914
0.020
Why?
Cerebral Cortex
1
2010
433
0.020
Why?
Gene Expression Regulation, Enzymologic
1
2007
283
0.020
Why?
Biological Transport
1
2007
416
0.020
Why?
DNA, Recombinant
1
2005
47
0.020
Why?
Endoderm
1
2005
19
0.020
Why?
Phytic Acid
1
2005
42
0.010
Why?
Microtubules
1
2007
270
0.010
Why?
Hippocampus
1
2010
894
0.010
Why?
Epithelium
1
2005
311
0.010
Why?
Genes, Dominant
1
2004
95
0.010
Why?
Ataxia Telangiectasia Mutated Proteins
1
2004
66
0.010
Why?
S Phase
1
2004
77
0.010
Why?
Heart
1
2008
653
0.010
Why?
Calcium Signaling
1
2005
249
0.010
Why?
Mice, Knockout
1
2010
3009
0.010
Why?
Apoptosis
1
2012
2552
0.010
Why?
Transfection
1
2004
941
0.010
Why?
Tumor Suppressor Proteins
1
2004
327
0.010
Why?
Intestinal Mucosa
1
2005
621
0.010
Why?
Epithelial Cells
1
2005
1094
0.010
Why?
Child
1
2017
21819
0.010
Why?
Maf Transcription Factors
1
1996
1
0.010
Why?
Cell Transplantation
1
1996
37
0.010
Why?
Mosaicism
1
1996
73
0.010
Why?
Genetic Markers
1
1996
344
0.010
Why?
Selection, Genetic
1
1996
264
0.010
Why?
Polymerase Chain Reaction
1
1996
1059
0.010
Why?
Appel's Networks
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