Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Bruce Appel

Concepts (305)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Zebrafish Proteins
52
2025
288
10.720
Why?
Zebrafish
69
2025
499
10.450
Why?
Oligodendroglia
36
2025
179
10.310
Why?
Myelin Sheath
23
2025
167
8.500
Why?
Spinal Cord
23
2025
370
4.720
Why?
Cell Differentiation
33
2025
1991
4.110
Why?
Axons
16
2025
198
4.050
Why?
Motor Neurons
18
2024
234
3.490
Why?
Gene Expression Regulation, Developmental
31
2025
860
3.030
Why?
Animals, Genetically Modified
31
2025
240
2.520
Why?
Hedgehog Proteins
10
2025
195
2.500
Why?
Nerve Tissue Proteins
18
2021
596
2.440
Why?
Neurogenesis
7
2021
149
2.400
Why?
Neural Stem Cells
6
2025
156
2.340
Why?
Stem Cells
15
2018
594
2.260
Why?
Signal Transduction
26
2025
5079
2.210
Why?
Basic Helix-Loop-Helix Transcription Factors
13
2021
243
1.700
Why?
Receptors, Notch
9
2025
88
1.680
Why?
Embryo, Nonmammalian
20
2021
167
1.670
Why?
Cell Lineage
15
2025
350
1.620
Why?
Cell Movement
10
2015
967
1.580
Why?
Oligodendrocyte Precursor Cells
2
2024
20
1.490
Why?
Body Patterning
13
2014
132
1.460
Why?
Neurons
15
2025
1590
1.420
Why?
Fragile X Mental Retardation Protein
3
2024
50
1.380
Why?
RNA-Binding Proteins
5
2021
422
1.330
Why?
Animals
74
2025
36940
1.330
Why?
Homeodomain Proteins
9
2015
506
1.160
Why?
Central Nervous System
5
2024
258
1.080
Why?
TOR Serine-Threonine Kinases
3
2021
412
1.070
Why?
Schwann Cells
4
2014
34
1.000
Why?
Brain-Derived Neurotrophic Factor
2
2025
131
0.970
Why?
Green Fluorescent Proteins
14
2016
390
0.960
Why?
Receptor, trkB
1
2025
33
0.940
Why?
Receptor, Notch1
5
2012
64
0.920
Why?
Cell Polarity
5
2016
141
0.910
Why?
Docosahexaenoic Acids
1
2024
84
0.870
Why?
Cytoplasmic Dyneins
2
2015
8
0.870
Why?
F-Box Proteins
2
2015
23
0.860
Why?
Oligodendrocyte Transcription Factor 2
11
2025
21
0.830
Why?
Cholesterol
2
2016
410
0.810
Why?
Maternal Nutritional Physiological Phenomena
1
2024
176
0.790
Why?
Mutation
17
2021
3958
0.790
Why?
Ubiquitin-Protein Ligases
2
2015
175
0.780
Why?
Membrane Proteins
8
2008
1164
0.760
Why?
Notochord
5
2006
14
0.740
Why?
Neural Cell Adhesion Molecules
1
2021
32
0.730
Why?
RNA Caps
1
2021
35
0.730
Why?
Rhombencephalon
3
2012
31
0.700
Why?
RNA Transport
1
2021
23
0.700
Why?
Transcription Factors
10
2021
1719
0.690
Why?
Cell Cycle Proteins
4
2015
617
0.680
Why?
3' Untranslated Regions
1
2021
145
0.660
Why?
MicroRNAs
3
2016
692
0.630
Why?
RNA, Messenger
8
2021
2833
0.620
Why?
Proto-Oncogene Proteins c-akt
1
2021
437
0.610
Why?
Carrier Proteins
4
2020
771
0.610
Why?
Protein Biosynthesis
1
2021
433
0.600
Why?
Phagocytosis
1
2020
380
0.570
Why?
Neuroglia
5
2018
173
0.520
Why?
Larva
5
2025
226
0.520
Why?
Myelin Proteins
1
2016
45
0.510
Why?
Cytogenetic Analysis
1
2016
33
0.500
Why?
Neural Crest
3
2014
118
0.500
Why?
Protein Kinase C
2
2025
261
0.490
Why?
Synapses
1
2019
427
0.480
Why?
Brain
4
2018
2668
0.460
Why?
Axonal Transport
1
2015
27
0.460
Why?
Cell Cycle
3
2013
601
0.450
Why?
Trans-Activators
4
2004
398
0.450
Why?
Hydroxymethylglutaryl-CoA Synthase
1
2014
2
0.440
Why?
Phosphatidylinositol 3-Kinases
1
2016
366
0.440
Why?
Pericytes
1
2013
34
0.420
Why?
DNA-Binding Proteins
3
2020
1502
0.410
Why?
SOXE Transcription Factors
2
2025
20
0.390
Why?
Demyelinating Diseases
1
2012
85
0.380
Why?
Peripheral Nerves
2
2012
65
0.370
Why?
Action Potentials
1
2015
493
0.370
Why?
Fragile X Syndrome
2
2024
77
0.360
Why?
Guanine Nucleotide Exchange Factors
1
2011
66
0.350
Why?
In Situ Hybridization
7
2013
316
0.340
Why?
Gene Expression Regulation
3
2017
2607
0.330
Why?
Cell Proliferation
7
2018
2475
0.310
Why?
Isoenzymes
1
2009
304
0.290
Why?
Genes, Reporter
4
2015
269
0.290
Why?
Organogenesis
2
2020
58
0.290
Why?
Adult Stem Cells
1
2007
40
0.270
Why?
Synaptic Vesicles
2
2019
44
0.270
Why?
Wnt Proteins
1
2008
133
0.270
Why?
Exocytosis
2
2019
89
0.270
Why?
Morphogenesis
3
2008
166
0.260
Why?
Cloning, Molecular
7
2008
534
0.250
Why?
Nuclear Proteins
1
2011
712
0.250
Why?
Cerebellum
1
2008
224
0.250
Why?
Cyclin-Dependent Kinase Inhibitor p57
1
2005
4
0.240
Why?
Myelin Basic Protein
3
2025
47
0.240
Why?
Cell Adhesion Molecules
2
2019
181
0.230
Why?
Chondroitin Sulfate Proteoglycans
1
2024
10
0.230
Why?
Morpholinos
2
2016
30
0.220
Why?
Time-Lapse Imaging
2
2015
21
0.220
Why?
Electrical Synapses
1
2024
11
0.220
Why?
F-Box-WD Repeat-Containing Protein 7
2
2015
6
0.220
Why?
Cell Count
2
2016
324
0.220
Why?
Ubiquitin-Protein Ligase Complexes
2
2015
7
0.220
Why?
Proteoglycans
1
2024
107
0.220
Why?
Bromodeoxyuridine
3
2010
79
0.220
Why?
Intracellular Signaling Peptides and Proteins
6
2003
455
0.220
Why?
Glycosyltransferases
1
2003
11
0.210
Why?
Cilia
3
2021
178
0.210
Why?
Retinoids
1
2003
34
0.210
Why?
Nervous System
2
2001
67
0.210
Why?
Models, Biological
6
2019
1783
0.210
Why?
Neuroepithelial Cells
2
2015
4
0.200
Why?
Veratrum Alkaloids
3
2008
19
0.200
Why?
Peripheral Nervous System
1
2003
20
0.200
Why?
Antigens
1
2024
357
0.200
Why?
Receptors, Cell Surface
2
2002
385
0.190
Why?
Amyloid beta-Peptides
1
2025
220
0.190
Why?
Purkinje Cells
1
2003
70
0.190
Why?
Intestines
2
2020
357
0.180
Why?
Microscopy, Confocal
2
2015
325
0.180
Why?
Spatio-Temporal Analysis
1
2021
34
0.180
Why?
Eukaryotic Initiation Factors
1
2021
10
0.180
Why?
Regulatory Sequences, Ribonucleic Acid
1
2021
19
0.170
Why?
Molecular Sequence Data
6
2012
2900
0.170
Why?
Molecular Imaging
1
2021
56
0.170
Why?
Extracellular Matrix
1
2024
528
0.170
Why?
Epigenesis, Genetic
1
2025
660
0.170
Why?
Tissue Distribution
1
2021
332
0.170
Why?
Microscopy, Electron, Transmission
2
2012
156
0.160
Why?
Superior Colliculi
1
2020
40
0.160
Why?
rab GTP-Binding Proteins
1
2020
75
0.160
Why?
Gastrula
3
2006
17
0.160
Why?
Vitamin B 12
2
2017
128
0.160
Why?
Embryonic Stem Cells
2
2010
129
0.150
Why?
Immunohistochemistry
3
2010
1738
0.150
Why?
Female
8
2024
73304
0.150
Why?
Host Cell Factor C1
2
2017
15
0.150
Why?
Interneurons
3
2024
122
0.150
Why?
Single-Cell Analysis
1
2021
313
0.150
Why?
Scoliosis
1
2021
215
0.140
Why?
Sequence Analysis, RNA
1
2021
452
0.140
Why?
Microglia
1
2020
251
0.140
Why?
Mice, Transgenic
2
2020
2167
0.130
Why?
Base Sequence
4
2017
2181
0.130
Why?
Neuronal Plasticity
1
2019
290
0.130
Why?
Phosphotransferases (Alcohol Group Acceptor)
2
2007
45
0.130
Why?
Pregnancy
2
2021
6763
0.120
Why?
Nerve Fibers, Myelinated
1
2015
47
0.120
Why?
Genes, Homeobox
1
1995
51
0.120
Why?
Oligonucleotides, Antisense
2
2008
112
0.120
Why?
Sequence Alignment
2
2012
343
0.120
Why?
Veratridine
1
2015
6
0.120
Why?
Tetrodotoxin
1
2015
39
0.120
Why?
Transcriptome
1
2021
971
0.120
Why?
Cell Division
2
2008
794
0.120
Why?
Potassium Channels, Inwardly Rectifying
1
2015
38
0.110
Why?
Gene Expression
3
2014
1502
0.110
Why?
Sirolimus
1
2016
276
0.110
Why?
Gene Expression Profiling
1
2021
1774
0.110
Why?
Cell Communication
1
2016
315
0.110
Why?
Receptor, Notch3
1
2013
5
0.110
Why?
Repressor Proteins
1
2017
427
0.110
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2013
29
0.110
Why?
Luciferases
1
2013
150
0.100
Why?
Immunoenzyme Techniques
1
2013
219
0.100
Why?
Protein Structure, Tertiary
1
2015
861
0.100
Why?
Cerebral Hemorrhage
1
2013
108
0.100
Why?
Colforsin
1
2012
53
0.100
Why?
Real-Time Polymerase Chain Reaction
1
2013
346
0.100
Why?
Blood-Brain Barrier
1
2013
138
0.100
Why?
Cell Membrane
1
2016
738
0.100
Why?
RNA
2
2012
921
0.100
Why?
Nucleocytoplasmic Transport Proteins
1
2012
7
0.100
Why?
Models, Genetic
2
2012
600
0.100
Why?
Recombinant Fusion Proteins
1
2015
665
0.100
Why?
Arthrogryposis
1
2012
8
0.100
Why?
Ligands
2
2004
664
0.090
Why?
rac GTP-Binding Proteins
1
2011
32
0.090
Why?
Cyclic AMP
1
2012
234
0.090
Why?
rac1 GTP-Binding Protein
1
2011
56
0.090
Why?
Neuropeptides
1
2011
73
0.090
Why?
Phenotype
4
2020
3196
0.090
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2013
976
0.090
Why?
Immunosuppressive Agents
1
2016
890
0.090
Why?
Mutagenesis
1
2012
179
0.090
Why?
Blotting, Western
1
2013
1226
0.090
Why?
Chromosome Mapping
1
2012
523
0.090
Why?
Enzyme Inhibitors
1
2014
840
0.080
Why?
Spinal Nerves
1
2009
5
0.080
Why?
Mice
4
2025
17787
0.080
Why?
Amino Acid Sequence
4
2005
2139
0.080
Why?
Adherens Junctions
1
2009
25
0.080
Why?
T-Box Domain Proteins
2
2008
98
0.080
Why?
Oligodeoxyribonucleotides, Antisense
1
2009
8
0.080
Why?
Caspase 3
1
2010
246
0.080
Why?
Microscopy, Electron
1
2009
443
0.080
Why?
Male
5
2021
67762
0.080
Why?
Sequence Homology, Amino Acid
3
2005
385
0.070
Why?
Calbindin 2
1
2008
8
0.070
Why?
Smoothened Receptor
1
2008
6
0.070
Why?
S100 Calcium Binding Protein G
1
2008
8
0.070
Why?
Zonula Occludens-1 Protein
1
2008
16
0.070
Why?
Oligonucleotide Array Sequence Analysis
1
2010
767
0.070
Why?
Glial Fibrillary Acidic Protein
1
2008
100
0.070
Why?
Time Factors
3
2010
6828
0.070
Why?
Fishes
1
2008
105
0.070
Why?
Morpholines
1
2008
122
0.070
Why?
Developmental Biology
1
2007
22
0.070
Why?
Recombinant Proteins
2
2007
1353
0.070
Why?
Cell Survival
1
2010
1120
0.070
Why?
Fetal Proteins
1
2006
17
0.060
Why?
Muscle Proteins
1
2008
231
0.060
Why?
Flow Cytometry
1
2010
1178
0.060
Why?
Humans
10
2021
137585
0.060
Why?
Intercellular Signaling Peptides and Proteins
1
2008
382
0.060
Why?
Branchial Region
2
2017
36
0.060
Why?
Receptors, G-Protein-Coupled
1
2008
220
0.060
Why?
Craniofacial Abnormalities
2
2017
72
0.060
Why?
Phosphoproteins
1
2008
338
0.060
Why?
Prosencephalon
1
2025
48
0.060
Why?
Microscopy, Fluorescence
1
2006
402
0.060
Why?
Models, Neurological
1
2007
242
0.060
Why?
Hyperkinesis
1
2024
16
0.060
Why?
Connexins
1
2024
48
0.050
Why?
Gap Junctions
1
2024
59
0.050
Why?
Helix-Loop-Helix Motifs
1
2003
12
0.050
Why?
Myocytes, Cardiac
1
2008
526
0.050
Why?
Catalytic Domain
1
2004
207
0.050
Why?
Microinjections
1
2003
86
0.050
Why?
Fibroblast Growth Factors
1
2003
172
0.050
Why?
Age Factors
1
2009
3295
0.050
Why?
Luminescent Proteins
1
2003
179
0.050
Why?
Genetic Vectors
1
2003
319
0.050
Why?
Embryonic and Fetal Development
1
2001
97
0.040
Why?
Mesoderm
1
2002
144
0.040
Why?
Mammals
1
2022
283
0.040
Why?
Microvilli
1
2020
78
0.040
Why?
Hot Temperature
1
2003
391
0.040
Why?
Bone and Bones
1
2022
317
0.040
Why?
Endosomes
1
2020
136
0.040
Why?
Disease Models, Animal
2
2024
4295
0.040
Why?
ELAV-Like Protein 3
1
1998
1
0.040
Why?
Evolution, Molecular
1
2002
493
0.040
Why?
ELAV Proteins
1
1998
14
0.040
Why?
Embryonic Induction
1
1998
31
0.040
Why?
Antigens, Surface
1
1998
154
0.030
Why?
Avian Proteins
1
1996
21
0.030
Why?
Primary Cell Culture
1
2017
171
0.030
Why?
Oncogene Proteins
1
1996
59
0.030
Why?
DNA Primers
1
1995
515
0.030
Why?
Protein Binding
1
2020
2224
0.030
Why?
Oxidoreductases
1
2014
92
0.030
Why?
Gene Knockdown Techniques
1
2014
327
0.030
Why?
Cells, Cultured
2
2011
4193
0.030
Why?
Chondrocytes
1
2014
212
0.020
Why?
Fibroblasts
1
2017
996
0.020
Why?
Rats
2
2011
5647
0.020
Why?
Plasmids
1
2012
363
0.020
Why?
Transcription, Genetic
1
2017
1457
0.020
Why?
SOXD Transcription Factors
1
2010
5
0.020
Why?
Cell Line
2
2007
2847
0.020
Why?
Chick Embryo
1
2010
130
0.020
Why?
Electroporation
1
2010
38
0.020
Why?
Ribonuclease III
1
2010
40
0.020
Why?
Endoribonucleases
1
2010
81
0.020
Why?
DEAD-box RNA Helicases
1
2010
76
0.020
Why?
Embryo, Mammalian
1
2010
232
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2011
430
0.020
Why?
Cell Nucleus
1
2012
620
0.020
Why?
Versicans
1
2008
5
0.020
Why?
Bone Morphogenetic Protein 4
1
2008
43
0.020
Why?
RNA, Small Interfering
1
2010
622
0.020
Why?
Centrosome
1
2007
71
0.020
Why?
Bone Morphogenetic Proteins
1
2008
135
0.020
Why?
Protozoan Proteins
1
2007
82
0.020
Why?
Oligonucleotides
1
2008
148
0.020
Why?
Genotype
1
2012
1916
0.020
Why?
Cerebral Cortex
1
2010
433
0.020
Why?
Gene Expression Regulation, Enzymologic
1
2007
283
0.020
Why?
Biological Transport
1
2007
418
0.020
Why?
DNA, Recombinant
1
2005
47
0.020
Why?
Endoderm
1
2005
19
0.020
Why?
Phytic Acid
1
2005
42
0.010
Why?
Microtubules
1
2007
279
0.010
Why?
Hippocampus
1
2010
895
0.010
Why?
Epithelium
1
2005
313
0.010
Why?
Genes, Dominant
1
2004
96
0.010
Why?
Ataxia Telangiectasia Mutated Proteins
1
2004
66
0.010
Why?
S Phase
1
2004
77
0.010
Why?
Heart
1
2008
655
0.010
Why?
Calcium Signaling
1
2005
249
0.010
Why?
Mice, Knockout
1
2010
3015
0.010
Why?
Apoptosis
1
2012
2553
0.010
Why?
Transfection
1
2004
945
0.010
Why?
Tumor Suppressor Proteins
1
2004
327
0.010
Why?
Intestinal Mucosa
1
2005
623
0.010
Why?
Epithelial Cells
1
2005
1096
0.010
Why?
Child
1
2017
21935
0.010
Why?
Maf Transcription Factors
1
1996
1
0.010
Why?
Cell Transplantation
1
1996
37
0.010
Why?
Mosaicism
1
1996
73
0.010
Why?
Genetic Markers
1
1996
344
0.010
Why?
Selection, Genetic
1
1996
273
0.010
Why?
Polymerase Chain Reaction
1
1996
1062
0.010
Why?
Appel's Networks
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