Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Bruce Appel

Concepts (308)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Zebrafish Proteins
55
2026
314
11.560
Why?
Oligodendroglia
39
2026
190
11.360
Why?
Zebrafish
72
2026
532
11.210
Why?
Myelin Sheath
24
2026
166
8.810
Why?
Spinal Cord
25
2026
382
5.240
Why?
Axons
17
2026
204
4.690
Why?
Cell Differentiation
35
2026
2046
4.020
Why?
Motor Neurons
18
2024
236
3.280
Why?
Gene Expression Regulation, Developmental
33
2026
910
3.060
Why?
Neural Stem Cells
8
2026
168
2.460
Why?
Animals, Genetically Modified
31
2025
246
2.390
Why?
Hedgehog Proteins
10
2025
200
2.360
Why?
Nerve Tissue Proteins
18
2021
591
2.330
Why?
Neurogenesis
8
2026
157
2.320
Why?
Oligodendrocyte Precursor Cells
3
2026
24
2.300
Why?
Stem Cells
15
2018
628
2.120
Why?
Signal Transduction
27
2026
5216
2.100
Why?
Cell Lineage
18
2026
377
1.980
Why?
Homeodomain Proteins
10
2026
523
1.790
Why?
Receptors, Notch
9
2025
90
1.590
Why?
Embryo, Nonmammalian
20
2021
171
1.570
Why?
Cell Movement
10
2015
959
1.490
Why?
Body Patterning
13
2014
138
1.380
Why?
Animals
77
2026
38030
1.350
Why?
Neurons
15
2025
1649
1.330
Why?
Membrane Proteins
9
2026
1164
1.330
Why?
Carrier Proteins
5
2026
728
1.300
Why?
RNA-Binding Proteins
5
2021
447
1.260
Why?
Central Nervous System
6
2026
282
1.200
Why?
TOR Serine-Threonine Kinases
3
2021
454
0.990
Why?
Schwann Cells
4
2014
33
0.950
Why?
GABAergic Neurons
1
2026
37
0.920
Why?
Brain-Derived Neurotrophic Factor
2
2025
154
0.910
Why?
Green Fluorescent Proteins
14
2016
407
0.900
Why?
Receptor, trkB
1
2025
39
0.880
Why?
Receptor, Notch1
5
2012
63
0.870
Why?
Cell Polarity
5
2016
137
0.870
Why?
Cytoplasmic Dyneins
2
2015
8
0.820
Why?
Docosahexaenoic Acids
1
2024
88
0.820
Why?
Transcription Factors
12
2026
1734
0.810
Why?
F-Box Proteins
2
2015
24
0.810
Why?
Oligodendrocyte Transcription Factor 2
11
2025
23
0.780
Why?
Cholesterol
2
2016
408
0.770
Why?
Maternal Nutritional Physiological Phenomena
1
2024
178
0.750
Why?
Mutation
17
2021
4075
0.750
Why?
Ubiquitin-Protein Ligases
2
2015
192
0.730
Why?
Larva
6
2026
240
0.710
Why?
Notochord
5
2006
14
0.700
Why?
RNA Caps
1
2021
32
0.690
Why?
Neural Cell Adhesion Molecules
1
2021
38
0.680
Why?
Rhombencephalon
3
2012
31
0.660
Why?
RNA Transport
1
2021
27
0.660
Why?
Cell Cycle Proteins
4
2015
630
0.640
Why?
3' Untranslated Regions
1
2021
149
0.630
Why?
MicroRNAs
3
2016
686
0.610
Why?
RNA, Messenger
8
2021
2803
0.580
Why?
Proto-Oncogene Proteins c-akt
1
2021
440
0.580
Why?
Phagocytosis
1
2020
296
0.560
Why?
Protein Biosynthesis
1
2021
452
0.550
Why?
Neuroglia
5
2018
173
0.490
Why?
Myelin Proteins
1
2016
45
0.480
Why?
Cytogenetic Analysis
1
2016
33
0.470
Why?
Neural Crest
3
2014
129
0.470
Why?
Protein Kinase C
2
2025
251
0.470
Why?
Synapses
1
2019
439
0.450
Why?
Axonal Transport
1
2015
26
0.440
Why?
Cell Cycle
3
2013
598
0.420
Why?
Trans-Activators
4
2004
396
0.420
Why?
Brain
4
2018
2947
0.420
Why?
Hydroxymethylglutaryl-CoA Synthase
1
2014
3
0.420
Why?
Phosphatidylinositol 3-Kinases
1
2016
382
0.410
Why?
DNA-Binding Proteins
3
2020
1480
0.390
Why?
Pericytes
1
2013
42
0.390
Why?
SOXE Transcription Factors
2
2025
22
0.370
Why?
Demyelinating Diseases
1
2012
84
0.360
Why?
Peripheral Nerves
2
2012
72
0.350
Why?
Action Potentials
1
2015
502
0.350
Why?
Fragile X Syndrome
2
2024
119
0.330
Why?
Guanine Nucleotide Exchange Factors
1
2011
63
0.330
Why?
In Situ Hybridization
7
2013
318
0.320
Why?
Gene Expression Regulation
3
2017
2597
0.310
Why?
Cell Proliferation
7
2018
2507
0.300
Why?
Isoenzymes
1
2009
294
0.280
Why?
Genes, Reporter
4
2015
277
0.270
Why?
Organogenesis
2
2020
63
0.270
Why?
Adult Stem Cells
1
2007
40
0.260
Why?
Synaptic Vesicles
2
2019
40
0.260
Why?
Wnt Proteins
1
2008
133
0.250
Why?
Exocytosis
2
2019
85
0.250
Why?
Morphogenesis
3
2008
172
0.240
Why?
Cloning, Molecular
7
2008
538
0.240
Why?
Nuclear Proteins
1
2011
740
0.240
Why?
Cerebellum
1
2008
224
0.230
Why?
Cyclin-Dependent Kinase Inhibitor p57
1
2005
5
0.230
Why?
Myelin Basic Protein
3
2025
44
0.230
Why?
Cell Adhesion Molecules
2
2019
181
0.220
Why?
Chondroitin Sulfate Proteoglycans
1
2024
10
0.220
Why?
Electrical Synapses
1
2024
6
0.210
Why?
Morpholinos
2
2016
29
0.210
Why?
Time-Lapse Imaging
2
2015
21
0.210
Why?
Cell Count
2
2016
319
0.210
Why?
F-Box-WD Repeat-Containing Protein 7
2
2015
6
0.210
Why?
Ubiquitin-Protein Ligase Complexes
2
2015
8
0.210
Why?
CRISPR-Cas Systems
1
2026
166
0.210
Why?
Intracellular Signaling Peptides and Proteins
6
2003
456
0.210
Why?
Proteoglycans
1
2024
112
0.210
Why?
Bromodeoxyuridine
3
2010
77
0.210
Why?
Cilia
3
2021
173
0.200
Why?
Glycosyltransferases
1
2003
16
0.200
Why?
Retinoids
1
2003
33
0.200
Why?
Models, Biological
6
2019
1764
0.200
Why?
Nervous System
2
2001
69
0.200
Why?
Neuroepithelial Cells
2
2015
4
0.190
Why?
Gene Regulatory Networks
1
2026
317
0.190
Why?
Veratrum Alkaloids
3
2008
20
0.190
Why?
Peripheral Nervous System
1
2003
20
0.190
Why?
Antigens
1
2024
348
0.190
Why?
Receptors, Cell Surface
2
2002
372
0.180
Why?
Amyloid beta-Peptides
1
2025
244
0.180
Why?
Purkinje Cells
1
2003
65
0.180
Why?
Intestines
2
2020
354
0.170
Why?
Microscopy, Confocal
2
2015
319
0.170
Why?
Spatio-Temporal Analysis
1
2021
34
0.170
Why?
Eukaryotic Initiation Factors
1
2021
12
0.170
Why?
Regulatory Sequences, Ribonucleic Acid
1
2021
18
0.170
Why?
Molecular Sequence Data
6
2012
2883
0.160
Why?
Molecular Imaging
1
2021
57
0.160
Why?
Epigenesis, Genetic
1
2025
679
0.160
Why?
Extracellular Matrix
1
2024
562
0.160
Why?
Tissue Distribution
1
2021
335
0.160
Why?
Microscopy, Electron, Transmission
2
2012
156
0.160
Why?
rab GTP-Binding Proteins
1
2020
76
0.150
Why?
Superior Colliculi
1
2020
44
0.150
Why?
Gastrula
3
2006
17
0.150
Why?
Immunohistochemistry
3
2010
1716
0.150
Why?
Vitamin B 12
2
2017
135
0.150
Why?
Embryonic Stem Cells
2
2010
124
0.150
Why?
Host Cell Factor C1
2
2017
15
0.140
Why?
Interneurons
3
2024
125
0.140
Why?
Sequence Analysis, RNA
1
2021
442
0.140
Why?
Scoliosis
1
2021
221
0.140
Why?
Female
8
2024
78845
0.140
Why?
Single-Cell Analysis
1
2021
362
0.130
Why?
Microglia
1
2020
270
0.130
Why?
Base Sequence
4
2017
2170
0.130
Why?
Mice, Transgenic
2
2020
2188
0.130
Why?
Neuronal Plasticity
1
2019
305
0.120
Why?
Phosphotransferases (Alcohol Group Acceptor)
2
2007
49
0.120
Why?
Nerve Fibers, Myelinated
1
2015
47
0.110
Why?
Genes, Homeobox
1
1995
50
0.110
Why?
Oligonucleotides, Antisense
2
2008
118
0.110
Why?
Pregnancy
2
2021
7202
0.110
Why?
Sequence Alignment
2
2012
362
0.110
Why?
Veratridine
1
2015
5
0.110
Why?
Tetrodotoxin
1
2015
40
0.110
Why?
Cell Division
2
2008
756
0.110
Why?
Potassium Channels, Inwardly Rectifying
1
2015
46
0.110
Why?
Transcriptome
1
2021
1038
0.110
Why?
Gene Expression
3
2014
1476
0.110
Why?
Sirolimus
1
2016
280
0.110
Why?
Gene Expression Profiling
1
2021
1767
0.100
Why?
Receptor, Notch3
1
2013
8
0.100
Why?
Repressor Proteins
1
2017
429
0.100
Why?
Cell Communication
1
2016
328
0.100
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2013
31
0.100
Why?
Fibroblast Growth Factors
2
2026
188
0.100
Why?
Luciferases
1
2013
153
0.100
Why?
Immunoenzyme Techniques
1
2013
200
0.100
Why?
Protein Structure, Tertiary
1
2015
855
0.100
Why?
Colforsin
1
2012
47
0.090
Why?
Real-Time Polymerase Chain Reaction
1
2013
337
0.090
Why?
RNA
2
2012
910
0.090
Why?
Cerebral Hemorrhage
1
2013
125
0.090
Why?
Mice
5
2026
18329
0.090
Why?
Models, Genetic
2
2012
524
0.090
Why?
Cell Membrane
1
2016
707
0.090
Why?
Blood-Brain Barrier
1
2013
160
0.090
Why?
Recombinant Fusion Proteins
1
2015
666
0.090
Why?
Nucleocytoplasmic Transport Proteins
1
2012
9
0.090
Why?
Arthrogryposis
1
2012
17
0.090
Why?
Ligands
2
2004
665
0.090
Why?
Cyclic AMP
1
2012
207
0.090
Why?
rac GTP-Binding Proteins
1
2011
35
0.090
Why?
Phenotype
4
2020
3155
0.090
Why?
rac1 GTP-Binding Protein
1
2011
56
0.090
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2013
977
0.090
Why?
Neuropeptides
1
2011
75
0.090
Why?
Immunosuppressive Agents
1
2016
838
0.090
Why?
Blotting, Western
1
2013
1179
0.080
Why?
Mutagenesis
1
2012
194
0.080
Why?
Chromosome Mapping
1
2012
506
0.080
Why?
Enzyme Inhibitors
1
2014
820
0.080
Why?
Spinal Nerves
1
2009
7
0.080
Why?
Amino Acid Sequence
4
2005
2129
0.080
Why?
Adherens Junctions
1
2009
24
0.070
Why?
Oligodeoxyribonucleotides, Antisense
1
2009
8
0.070
Why?
Caspase 3
1
2010
242
0.070
Why?
T-Box Domain Proteins
2
2008
106
0.070
Why?
Microscopy, Electron
1
2009
414
0.070
Why?
Sequence Homology, Amino Acid
3
2005
387
0.070
Why?
Male
5
2021
72843
0.070
Why?
S100 Calcium Binding Protein G
1
2008
8
0.070
Why?
Smoothened Receptor
1
2008
6
0.070
Why?
Oligonucleotide Array Sequence Analysis
1
2010
749
0.070
Why?
Calbindin 2
1
2008
12
0.070
Why?
Zonula Occludens-1 Protein
1
2008
17
0.070
Why?
Glial Fibrillary Acidic Protein
1
2008
122
0.070
Why?
Time Factors
3
2010
7123
0.060
Why?
Fishes
1
2008
109
0.060
Why?
Recombinant Proteins
2
2007
1368
0.060
Why?
Morpholines
1
2008
130
0.060
Why?
Developmental Biology
1
2007
24
0.060
Why?
Cell Survival
1
2010
1100
0.060
Why?
Fetal Proteins
1
2006
15
0.060
Why?
Intercellular Signaling Peptides and Proteins
1
2008
376
0.060
Why?
Flow Cytometry
1
2010
1162
0.060
Why?
Muscle Proteins
1
2008
242
0.060
Why?
Branchial Region
2
2017
40
0.060
Why?
Humans
10
2021
145475
0.060
Why?
Receptors, G-Protein-Coupled
1
2008
231
0.060
Why?
Neocortex
1
2026
49
0.060
Why?
Phosphoproteins
1
2008
337
0.060
Why?
Craniofacial Abnormalities
2
2017
78
0.060
Why?
Prosencephalon
1
2025
54
0.060
Why?
Microscopy, Fluorescence
1
2006
408
0.050
Why?
Models, Neurological
1
2007
250
0.050
Why?
Hyperkinesis
1
2024
16
0.050
Why?
Connexins
1
2024
54
0.050
Why?
Helix-Loop-Helix Motifs
1
2003
12
0.050
Why?
Gap Junctions
1
2024
67
0.050
Why?
Catalytic Domain
1
2004
234
0.050
Why?
Myocytes, Cardiac
1
2008
546
0.050
Why?
Microinjections
1
2003
92
0.050
Why?
Age Factors
1
2009
3342
0.040
Why?
Luminescent Proteins
1
2003
186
0.040
Why?
Phosphorylation
1
2026
1707
0.040
Why?
Embryonic and Fetal Development
1
2001
93
0.040
Why?
Genetic Vectors
1
2003
335
0.040
Why?
Mesoderm
1
2002
147
0.040
Why?
Mammals
1
2022
286
0.040
Why?
Microvilli
1
2020
75
0.040
Why?
Hot Temperature
1
2003
396
0.040
Why?
Bone and Bones
1
2022
317
0.040
Why?
Endosomes
1
2020
140
0.040
Why?
Disease Models, Animal
2
2024
4560
0.040
Why?
Evolution, Molecular
1
2002
492
0.030
Why?
ELAV-Like Protein 3
1
1998
1
0.030
Why?
ELAV Proteins
1
1998
14
0.030
Why?
Embryonic Induction
1
1998
31
0.030
Why?
Antigens, Surface
1
1998
155
0.030
Why?
Avian Proteins
1
1996
21
0.030
Why?
Primary Cell Culture
1
2017
172
0.030
Why?
Oncogene Proteins
1
1996
62
0.030
Why?
DNA Primers
1
1995
505
0.030
Why?
Protein Binding
1
2020
2238
0.030
Why?
Oxidoreductases
1
2014
91
0.030
Why?
Gene Knockdown Techniques
1
2014
333
0.020
Why?
Cells, Cultured
2
2011
4148
0.020
Why?
Chondrocytes
1
2014
232
0.020
Why?
Rats
2
2011
5584
0.020
Why?
Fibroblasts
1
2017
1025
0.020
Why?
Transcription, Genetic
1
2017
1454
0.020
Why?
Plasmids
1
2012
373
0.020
Why?
Cell Line
2
2007
2823
0.020
Why?
SOXD Transcription Factors
1
2010
5
0.020
Why?
Chick Embryo
1
2010
132
0.020
Why?
Ribonuclease III
1
2010
43
0.020
Why?
Electroporation
1
2010
43
0.020
Why?
Endoribonucleases
1
2010
77
0.020
Why?
DEAD-box RNA Helicases
1
2010
83
0.020
Why?
Embryo, Mammalian
1
2010
234
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2011
425
0.020
Why?
Cell Nucleus
1
2012
588
0.020
Why?
Versicans
1
2008
9
0.020
Why?
Bone Morphogenetic Protein 4
1
2008
44
0.020
Why?
Centrosome
1
2007
71
0.020
Why?
RNA, Small Interfering
1
2010
637
0.020
Why?
Bone Morphogenetic Proteins
1
2008
143
0.020
Why?
Protozoan Proteins
1
2007
90
0.020
Why?
Oligonucleotides
1
2008
153
0.020
Why?
Genotype
1
2012
1852
0.020
Why?
Gene Expression Regulation, Enzymologic
1
2007
267
0.020
Why?
Biological Transport
1
2007
424
0.020
Why?
Cerebral Cortex
1
2010
473
0.010
Why?
DNA, Recombinant
1
2005
48
0.010
Why?
Endoderm
1
2005
21
0.010
Why?
Microtubules
1
2007
265
0.010
Why?
Phytic Acid
1
2005
35
0.010
Why?
Epithelium
1
2005
310
0.010
Why?
Genes, Dominant
1
2004
100
0.010
Why?
Ataxia Telangiectasia Mutated Proteins
1
2004
69
0.010
Why?
S Phase
1
2004
78
0.010
Why?
Hippocampus
1
2010
971
0.010
Why?
Heart
1
2008
626
0.010
Why?
Calcium Signaling
1
2005
245
0.010
Why?
Apoptosis
1
2012
2440
0.010
Why?
Mice, Knockout
1
2010
3124
0.010
Why?
Transfection
1
2004
926
0.010
Why?
Tumor Suppressor Proteins
1
2004
321
0.010
Why?
Intestinal Mucosa
1
2005
675
0.010
Why?
Epithelial Cells
1
2005
1131
0.010
Why?
Child
1
2017
22707
0.010
Why?
Maf Transcription Factors
1
1996
1
0.010
Why?
Cell Transplantation
1
1996
39
0.010
Why?
Mosaicism
1
1996
73
0.010
Why?
Genetic Markers
1
1996
335
0.010
Why?
Selection, Genetic
1
1996
261
0.010
Why?
Polymerase Chain Reaction
1
1996
1041
0.010
Why?
Appel's Networks
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