 Oligodendrocyte Transcription Factor 2
"Oligodendrocyte Transcription Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic helix-loop-helix transcription factor that is required for differentiation of OLIGODENDROCYTES and motor neurons in the spinal cord, and development of somatic motor neurons in the hindbrain.
| Descriptor ID |
D000076104
|
| MeSH Number(s) |
D12.776.260.103.798 D12.776.631.654 D12.776.930.125.782
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oligodendrocyte Transcription Factor 2".
Below are MeSH descriptors whose meaning is more specific than "Oligodendrocyte Transcription Factor 2".
This graph shows the total number of publications written about "Oligodendrocyte Transcription Factor 2" by people in this website by year, and whether "Oligodendrocyte Transcription Factor 2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 3 | 3 | | 2009 | 0 | 3 | 3 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 1 | 0 | 1 | | 2022 | 1 | 0 | 1 | | 2025 | 0 | 1 | 1 | | 2026 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Oligodendrocyte Transcription Factor 2" by people in Profiles.
-
Lindsay H, Du Y, Qi L, Zhang H, Zhao S, Braun FK, Kogiso M, Stephan C, Alton G, Stein G, Beaton G, Kesari S, Neuhauser S, Stearns T, Chuang J, Jocoy EL, Bult CJ, Teicher B, Smith MA, Li XN. Targeting Pediatric Glioblastomas by Combining OLIG2 Inhibitor CT-179 with Fractionated Radiation in a Panel of Patient-Derived Orthotopic Xenograft Mouse Models. Int J Mol Sci. 2026 Feb 04; 27(3).
-
Balantzategi U, Gaminde-Blasco A, Kearns CA, Bayón-Cordero L, Sánchez-Gómez MV, Zugaza JL, Appel B, Alberdi E. Amyloid-ß Dysregulates Oligodendroglial Lineage Cell Dynamics and Myelination via PKC in the Zebrafish Spinal Cord. Glia. 2025 Jul; 73(7):1437-1451.
-
Embalabala RJ, Brockman AA, Jurewicz AR, Kong JA, Ryan K, Guinto CD, Álvarez-Buylla A, Chiang C, Ihrie RA. GLI3 Is Required for OLIG2+ Progeny Production in Adult Dorsal Neural Stem Cells. Cells. 2022 01 10; 11(2).
-
Raghavan SS, Mooney KL, Folpe AL, Charville GW. OLIG2 is a marker of the fusion protein-driven neurodevelopmental transcriptional signature in alveolar rhabdomyosarcoma. Hum Pathol. 2019 09; 91:77-85.
-
Ghosh P, Maurer JM, Sagerström CG. Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish. Neural Dev. 2018 06 26; 13(1):13.
-
Anderson JL, Muraleedharan R, Oatman N, Klotter A, Sengupta S, Waclaw RR, Wu J, Drissi R, Miles L, Raabe EH, Weirauch ML, Fouladi M, Chow LM, Hoffman L, DeWire M, Dasgupta B. The transcription factor Olig2 is important for the biology of diffuse intrinsic pontine gliomas. Neuro Oncol. 2017 08 01; 19(8):1068-1078.
-
Ravanelli AM, Appel B. Motor neurons and oligodendrocytes arise from distinct cell lineages by progenitor recruitment. Genes Dev. 2015 Dec 01; 29(23):2504-15.
-
Sachs HH, Bercury KK, Popescu DC, Narayanan SP, Macklin WB. A new model of cuprizone-mediated demyelination/remyelination. ASN Neuro. 2014; 6(5).
-
Wrzos C, Winkler A, Metz I, Kayser DM, Thal DR, Wegner C, Brück W, Nessler S, Bennett JL, Stadelmann C. Early loss of oligodendrocytes in human and experimental neuromyelitis optica lesions. Acta Neuropathol. 2014 Apr; 127(4):523-38.
-
Zannino DA, Sagerström CG, Appel B. olig2-Expressing hindbrain cells are required for migrating facial motor neurons. Dev Dyn. 2012 Feb; 241(2):315-26.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|