Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Connection

Bruce Appel to Animals

This is a "connection" page, showing publications Bruce Appel has written about Animals.

 
Connection Strength
 
 
 
1.145
 
  1. Ranard KM, Appel B. Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment. J Lipid Res. 2025 Jan; 66(1):100716.
    View in: PubMed
    Score: 0.050
  2. Bromley-Coolidge S, Iruegas D, Appel B. Cspg4 sculpts oligodendrocyte precursor cell morphology. Differentiation. 2024 Nov-Dec; 140:100819.
    View in: PubMed
    Score: 0.049
  3. Kearns CA, Walker M, Ravanelli AM, Scott K, Arzbecker MR, Appel B. Zebrafish spinal cord oligodendrocyte formation requires boc function. Genetics. 2021 08 09; 218(4).
    View in: PubMed
    Score: 0.039
  4. Doll CA, Scott K, Appel B. Fmrp regulates oligodendrocyte lineage cell specification and differentiation. Glia. 2021 10; 69(10):2349-2361.
    View in: PubMed
    Score: 0.039
  5. Yergert KM, Doll CA, O'Rouke R, Hines JH, Appel B. Identification of 3' UTR motifs required for mRNA localization to myelin sheaths in vivo. PLoS Biol. 2021 01; 19(1):e3001053.
    View in: PubMed
    Score: 0.038
  6. Scott K, O'Rourke R, Gillen A, Appel B. Prdm8 regulates pMN progenitor specification for motor neuron and oligodendrocyte fates by modulating the Shh signaling response. Development. 2020 08 27; 147(16).
    View in: PubMed
    Score: 0.037
  7. Doll CA, Yergert KM, Appel BH. The RNA binding protein fragile X mental retardation protein promotes myelin sheath growth. Glia. 2020 03; 68(3):495-508.
    View in: PubMed
    Score: 0.035
  8. Hughes AN, Appel B. Oligodendrocytes express synaptic proteins that modulate myelin sheath formation. Nat Commun. 2019 09 11; 10(1):4125.
    View in: PubMed
    Score: 0.035
  9. Ravanelli AM, Kearns CA, Powers RK, Wang Y, Hines JH, Donaldson MJ, Appel B. Sequential specification of oligodendrocyte lineage cells by distinct levels of Hedgehog and Notch signaling. Dev Biol. 2018 12 15; 444(2):93-106.
    View in: PubMed
    Score: 0.032
  10. Mathews ES, Appel B. Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling. J Neurosci. 2016 07 20; 36(29):7628-39.
    View in: PubMed
    Score: 0.028
  11. Hudish LI, Galati DF, Ravanelli AM, Pearson CG, Huang P, Appel B. miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling. Development. 2016 07 01; 143(13):2292-304.
    View in: PubMed
    Score: 0.027
  12. Mathews ES, Appel B. Oligodendrocyte differentiation. Methods Cell Biol. 2016; 134:69-96.
    View in: PubMed
    Score: 0.027
  13. Ravanelli AM, Appel B. Motor neurons and oligodendrocytes arise from distinct cell lineages by progenitor recruitment. Genes Dev. 2015 Dec 01; 29(23):2504-15.
    View in: PubMed
    Score: 0.027
  14. Kearns CA, Ravanelli AM, Cooper K, Appel B. Fbxw7 Limits Myelination by Inhibiting mTOR Signaling. J Neurosci. 2015 Nov 04; 35(44):14861-71.
    View in: PubMed
    Score: 0.026
  15. Hines JH, Ravanelli AM, Schwindt R, Scott EK, Appel B. Neuronal activity biases axon selection for myelination in vivo. Nat Neurosci. 2015 May; 18(5):683-9.
    View in: PubMed
    Score: 0.025
  16. Blasky AJ, Pan L, Moens CB, Appel B. Pard3 regulates contact between neural crest cells and the timing of Schwann cell differentiation but is not essential for neural crest migration or myelination. Dev Dyn. 2014 Dec; 243(12):1511-23.
    View in: PubMed
    Score: 0.024
  17. Mathews ES, Mawdsley DJ, Walker M, Hines JH, Pozzoli M, Appel B. Mutation of 3-hydroxy-3-methylglutaryl CoA synthase I reveals requirements for isoprenoid and cholesterol synthesis in oligodendrocyte migration arrest, axon wrapping, and myelin gene expression. J Neurosci. 2014 Feb 26; 34(9):3402-12.
    View in: PubMed
    Score: 0.024
  18. Wang Y, Pan L, Moens CB, Appel B. Notch3 establishes brain vascular integrity by regulating pericyte number. Development. 2014 Jan; 141(2):307-17.
    View in: PubMed
    Score: 0.023
  19. Hudish LI, Blasky AJ, Appel B. miR-219 regulates neural precursor differentiation by direct inhibition of apical par polarity proteins. Dev Cell. 2013 Nov 25; 27(4):387-98.
    View in: PubMed
    Score: 0.023
  20. Langworthy MM, Appel B. Schwann cell myelination requires Dynein function. Neural Dev. 2012 Nov 20; 7:37.
    View in: PubMed
    Score: 0.022
  21. Snyder JL, Kearns CA, Appel B. Fbxw7 regulates Notch to control specification of neural precursors for oligodendrocyte fate. Neural Dev. 2012 May 03; 7:15.
    View in: PubMed
    Score: 0.021
  22. Simmons T, Appel B. Mutation of pescadillo disrupts oligodendrocyte formation in zebrafish. PLoS One. 2012; 7(2):e32317.
    View in: PubMed
    Score: 0.020
  23. Zannino DA, Sagerstr?m CG, Appel B. olig2-Expressing hindbrain cells are required for migrating facial motor neurons. Dev Dyn. 2012 Feb; 241(2):315-26.
    View in: PubMed
    Score: 0.020
  24. Takada N, Appel B. swap70 promotes neural precursor cell cycle exit and oligodendrocyte formation. Mol Cell Neurosci. 2011 Nov; 48(3):225-35.
    View in: PubMed
    Score: 0.020
  25. Takada N, Appel B. Identification of genes expressed by zebrafish oligodendrocytes using a differential microarray screen. Dev Dyn. 2010 Jul; 239(7):2041-7.
    View in: PubMed
    Score: 0.018
  26. Takada N, Kucenas S, Appel B. Sox10 is necessary for oligodendrocyte survival following axon wrapping. Glia. 2010 Jun; 58(8):996-1006.
    View in: PubMed
    Score: 0.018
  27. Kucenas S, Wang WD, Knapik EW, Appel B. A selective glial barrier at motor axon exit points prevents oligodendrocyte migration from the spinal cord. J Neurosci. 2009 Dec 02; 29(48):15187-94.
    View in: PubMed
    Score: 0.018
  28. Roberts RK, Appel B. Apical polarity protein PrkCi is necessary for maintenance of spinal cord precursors in zebrafish. Dev Dyn. 2009 Jul; 238(7):1638-48.
    View in: PubMed
    Score: 0.017
  29. Zannino DA, Appel B. Olig2+ precursors produce abducens motor neurons and oligodendrocytes in the zebrafish hindbrain. J Neurosci. 2009 Feb 25; 29(8):2322-33.
    View in: PubMed
    Score: 0.017
  30. Kim H, Shin J, Kim S, Poling J, Park HC, Appel B. Notch-regulated oligodendrocyte specification from radial glia in the spinal cord of zebrafish embryos. Dev Dyn. 2008 Aug; 237(8):2081-9.
    View in: PubMed
    Score: 0.016
  31. Kucenas S, Snell H, Appel B. nkx2.2a promotes specification and differentiation of a myelinating subset of oligodendrocyte lineage cells in zebrafish. Neuron Glia Biol. 2008 May; 4(2):71-81.
    View in: PubMed
    Score: 0.016
  32. McFarland KA, Topczewska JM, Weidinger G, Dorsky RI, Appel B. Hh and Wnt signaling regulate formation of olig2+ neurons in the zebrafish cerebellum. Dev Biol. 2008 Jun 01; 318(1):162-71.
    View in: PubMed
    Score: 0.016
  33. Kucenas S, Takada N, Park HC, Woodruff E, Broadie K, Appel B. CNS-derived glia ensheath peripheral nerves and mediate motor root development. Nat Neurosci. 2008 Feb; 11(2):143-51.
    View in: PubMed
    Score: 0.015
  34. Park HC, Shin J, Roberts RK, Appel B. An olig2 reporter gene marks oligodendrocyte precursors in the postembryonic spinal cord of zebrafish. Dev Dyn. 2007 Dec; 236(12):3402-7.
    View in: PubMed
    Score: 0.015
  35. Shin J, Poling J, Park HC, Appel B. Notch signaling regulates neural precursor allocation and binary neuronal fate decisions in zebrafish. Development. 2007 May; 134(10):1911-20.
    View in: PubMed
    Score: 0.015
  36. Kirby BB, Takada N, Latimer AJ, Shin J, Carney TJ, Kelsh RN, Appel B. In vivo time-lapse imaging shows dynamic oligodendrocyte progenitor behavior during zebrafish development. Nat Neurosci. 2006 Dec; 9(12):1506-11.
    View in: PubMed
    Score: 0.014
  37. Latimer AJ, Appel B. Notch signaling regulates midline cell specification and proliferation in zebrafish. Dev Biol. 2006 Oct 15; 298(2):392-402.
    View in: PubMed
    Score: 0.014
  38. Park HC, Boyce J, Shin J, Appel B. Oligodendrocyte specification in zebrafish requires notch-regulated cyclin-dependent kinase inhibitor function. J Neurosci. 2005 Jul 20; 25(29):6836-44.
    View in: PubMed
    Score: 0.013
  39. Latimer AJ, Shin J, Appel B. her9 promotes floor plate development in zebrafish. Dev Dyn. 2005 Apr; 232(4):1098-104.
    View in: PubMed
    Score: 0.013
  40. Park HC, Shin J, Appel B. Spatial and temporal regulation of ventral spinal cord precursor specification by Hedgehog signaling. Development. 2004 Dec; 131(23):5959-69.
    View in: PubMed
    Score: 0.012
  41. Miles KD, Barker CM, Russell KP, Appel BH, Doll CA. Electrical Synapses Mediate Embryonic Hyperactivity in a Zebrafish Model of Fragile X Syndrome. J Neurosci. 2024 Jul 31; 44(31).
    View in: PubMed
    Score: 0.012
  42. Appel B, Marasco P, McClung LE, Latimer AJ. lunatic fringe regulates Delta-Notch induction of hypochord in zebrafish. Dev Dyn. 2003 Oct; 228(2):281-6.
    View in: PubMed
    Score: 0.011
  43. Park HC, Appel B. Delta-Notch signaling regulates oligodendrocyte specification. Development. 2003 Aug; 130(16):3747-55.
    View in: PubMed
    Score: 0.011
  44. Shin J, Park HC, Topczewska JM, Mawdsley DJ, Appel B. Neural cell fate analysis in zebrafish using olig2 BAC transgenics. Methods Cell Sci. 2003; 25(1-2):7-14.
    View in: PubMed
    Score: 0.011
  45. Stenzel A, Mumme-Monheit A, Sucharov J, Walker M, Mitchell JM, Appel B, Nichols JT. Distinct and redundant roles for zebrafish her genes during mineralization and craniofacial patterning. Front Endocrinol (Lausanne). 2022; 13:1033843.
    View in: PubMed
    Score: 0.011
  46. Park HC, Mehta A, Richardson JS, Appel B. olig2 is required for zebrafish primary motor neuron and oligodendrocyte development. Dev Biol. 2002 Aug 15; 248(2):356-68.
    View in: PubMed
    Score: 0.011
  47. Latimer AJ, Dong X, Markov Y, Appel B. Delta-Notch signaling induces hypochord development in zebrafish. Development. 2002 Jun; 129(11):2555-63.
    View in: PubMed
    Score: 0.010
  48. Appel B, Chitnis A. Neurogenesis and specification of neuronal identity. Results Probl Cell Differ. 2002; 40:237-51.
    View in: PubMed
    Score: 0.010
  49. Appel B, Givan LA, Eisen JS. Delta-Notch signaling and lateral inhibition in zebrafish spinal cord development. BMC Dev Biol. 2001; 1:13.
    View in: PubMed
    Score: 0.010
  50. Terhune EA, Cuevas MT, Monley AM, Wethey CI, Chen X, Cattell MV, Bayrak MN, Bland MR, Sutphin B, Trahan GD, Taylor MRG, Niswander LA, Jones KL, Baschal EE, Antunes L, Dobbs M, Gurnett C, Appel B, Gray R, Hadley Miller N. Mutations in KIF7 implicated in idiopathic scoliosis in humans and axial curvatures in zebrafish. Hum Mutat. 2021 04; 42(4):392-407.
    View in: PubMed
    Score: 0.010
  51. Jewett CE, Appel BH, Prekeris R. The Rab11 effectors Fip5 and Fip1 regulate zebrafish intestinal development. Biol Open. 2020 10 23; 9(10).
    View in: PubMed
    Score: 0.009
  52. Appel B. Zebrafish neural induction and patterning. Dev Dyn. 2000 Oct; 219(2):155-68.
    View in: PubMed
    Score: 0.009
  53. Appel B, Fritz A, Westerfield M, Grunwald DJ, Eisen JS, Riley BB. Delta-mediated specification of midline cell fates in zebrafish embryos. Curr Biol. 1999 Mar 11; 9(5):247-56.
    View in: PubMed
    Score: 0.008
  54. Appel B, Eisen JS. Regulation of neuronal specification in the zebrafish spinal cord by Delta function. Development. 1998 Feb; 125(3):371-80.
    View in: PubMed
    Score: 0.008
  55. Appel B, Korzh V, Glasgow E, Thor S, Edlund T, Dawid IB, Eisen JS. Motoneuron fate specification revealed by patterned LIM homeobox gene expression in embryonic zebrafish. Development. 1995 Dec; 121(12):4117-25.
    View in: PubMed
    Score: 0.007
  56. Quintana AM, Geiger EA, Achilly N, Rosenblatt DS, Maclean KN, Stabler SP, Artinger KB, Appel B, Shaikh TH. Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating mmachc expression. Dev Biol. 2014 Dec 01; 396(1):94-106.
    View in: PubMed
    Score: 0.006
  57. Jao LE, Appel B, Wente SR. A zebrafish model of lethal congenital contracture syndrome 1 reveals Gle1 function in spinal neural precursor survival and motor axon arborization. Development. 2012 Apr; 139(7):1316-26.
    View in: PubMed
    Score: 0.005
  58. Tep C, Kim ML, Opincariu LI, Limpert AS, Chan JR, Appel B, Carter BD, Yoon SO. Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein. J Biol Chem. 2012 Jan 06; 287(2):1600-8.
    View in: PubMed
    Score: 0.005
  59. Zhao X, He X, Han X, Yu Y, Ye F, Chen Y, Hoang T, Xu X, Mi QS, Xin M, Wang F, Appel B, Lu QR. MicroRNA-mediated control of oligodendrocyte differentiation. Neuron. 2010 Mar 11; 65(5):612-26.
    View in: PubMed
    Score: 0.004
  60. Qu X, Jia H, Garrity DM, Tompkins K, Batts L, Appel B, Zhong TP, Baldwin HS. Ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish. Dev Biol. 2008 May 15; 317(2):486-96.
    View in: PubMed
    Score: 0.004
  61. Sarmah B, Winfrey VP, Olson GE, Appel B, Wente SR. A role for the inositol kinase Ipk1 in ciliary beating and length maintenance. Proc Natl Acad Sci U S A. 2007 Dec 11; 104(50):19843-8.
    View in: PubMed
    Score: 0.004
  62. Ng AN, de Jong-Curtain TA, Mawdsley DJ, White SJ, Shin J, Appel B, Dong PD, Stainier DY, Heath JK. Formation of the digestive system in zebrafish: III. Intestinal epithelium morphogenesis. Dev Biol. 2005 Oct 01; 286(1):114-35.
    View in: PubMed
    Score: 0.003
  63. Sarmah B, Latimer AJ, Appel B, Wente SR. Inositol polyphosphates regulate zebrafish left-right asymmetry. Dev Cell. 2005 Jul; 9(1):133-45.
    View in: PubMed
    Score: 0.003
  64. Garg R, Geng CD, Miller JL, Callens S, Tang X, Appel B, Xu B. Molecular cloning and characterization of the catalytic domain of zebrafish homologue of the ataxia-telangiectasia mutated gene. Mol Cancer Res. 2004 Jun; 2(6):348-53.
    View in: PubMed
    Score: 0.003
  65. Moens CB, Yan YL, Appel B, Force AG, Kimmel CB. valentino: a zebrafish gene required for normal hindbrain segmentation. Development. 1996 Dec; 122(12):3981-90.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2025 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)