 Basic Helix-Loop-Helix Transcription Factors
"Basic Helix-Loop-Helix Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of DNA-binding transcription factors that contain a basic HELIX-LOOP-HELIX MOTIF.
| Descriptor ID |
D051792
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| MeSH Number(s) |
D12.776.260.103 D12.776.930.125
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Basic Helix-Loop-Helix Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "Basic Helix-Loop-Helix Transcription Factors".
This graph shows the total number of publications written about "Basic Helix-Loop-Helix Transcription Factors" by people in this website by year, and whether "Basic Helix-Loop-Helix Transcription Factors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2000 | 0 | 1 | 1 | | 2001 | 0 | 7 | 7 | | 2002 | 0 | 5 | 5 | | 2003 | 0 | 7 | 7 | | 2004 | 0 | 3 | 3 | | 2005 | 0 | 2 | 2 | | 2006 | 4 | 4 | 8 | | 2007 | 7 | 1 | 8 | | 2008 | 4 | 5 | 9 | | 2009 | 4 | 2 | 6 | | 2010 | 2 | 6 | 8 | | 2011 | 4 | 9 | 13 | | 2012 | 8 | 4 | 12 | | 2013 | 13 | 4 | 17 | | 2014 | 3 | 3 | 6 | | 2015 | 6 | 3 | 9 | | 2016 | 6 | 3 | 9 | | 2017 | 8 | 4 | 12 | | 2018 | 2 | 2 | 4 | | 2019 | 6 | 4 | 10 | | 2020 | 4 | 3 | 7 | | 2021 | 5 | 2 | 7 | | 2022 | 1 | 3 | 4 | | 2023 | 1 | 0 | 1 | | 2024 | 4 | 2 | 6 | | 2025 | 1 | 3 | 4 |
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Below are the most recent publications written about "Basic Helix-Loop-Helix Transcription Factors" by people in Profiles.
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Tsaktanis T, Ammon L, Lößlein L, Peter A, Vandrey O, Naumann UJ, Behne M, Cook LJ, Levy M, Yeaman MR, Bennett JL, Rothhammer V. Serum Levels of Aryl Hydrocarbon Receptor Plasma Agonist Activity Are Reduced in Patients With NMOSD and Correlate With Disease Activity. Neurol Neuroimmunol Neuroinflamm. 2025 09; 12(5):e200457.
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Taslimi A, Jeibmann A, Goett-Zink L, Kottke T, Tucker CL. Constitutively active Arabidopsis cryptochrome 2 alleles identified using yeast selection and deep mutational scanning. J Biol Chem. 2025 Jun; 301(6):110265.
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Sasse SK, Dahlin A, Sanford L, Gruca MA, Gupta A, Gally F, Wu AC, Iribarren C, Dowell RD, Weiss ST, Gerber AN. Enhancer RNA transcription pinpoints functional genetic variants linked to asthma. Nat Commun. 2025 Mar 31; 16(1):2750.
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Flynn A, Pattison AD, Balachander S, Boehm E, Bowen B, Dwight T, Rossello FJ, Hofmann O, Martelotto L, Zethoven M, Kirschner LS, Else T, Fishbein L, Gill AJ, Tischler AS, Giordano T, Prodanov T, Noble JR, Reddel RR, Trainer AH, Ghayee HK, Bourdeau I, Elston M, Ishak D, Ngeow Yuen Yie J, Hicks RJ, Crona J, Åkerström T, Stålberg P, Dahia P, Grimmond S, Clifton-Bligh R, Pacak K, Tothill RW. Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles. Nat Commun. 2025 Mar 17; 16(1):2632.
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Johansen AKZ, Kasam RK, Vagnozzi RJ, Lin SJ, Gomez-Arroyo J, Shittu A, Bowers SLK, Kuwabara Y, Grimes KM, Warrick K, Sargent MA, Baldwin TA, Quaggin SE, Barski A, Molkentin JD. Transcription Factor 21 Regulates Cardiac Myofibroblast Formation and Fibrosis. Circ Res. 2025 Jan 03; 136(1):44-58.
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Eckhardt CM, Balte P, Morris JE, Bhatt SP, Couper D, Fetterman J, Freedman N, Jacobs DR, Hou L, Kalhan R, Liu Y, Loehr L, Lutsey PL, Schwartz JE, White W, Yende S, London SJ, Sanchez TR, Oelsner EC. Non-cigarette tobacco products, aryl-hydrocarbon receptor repressor gene methylation and smoking-related health outcomes. Thorax. 2024 10 16; 79(11):1060-1068.
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Czopik AK, McNamee EN, Vaughn V, Huang X, Bang IH, Clark T, Wang Y, Ruan W, Nguyen T, Masterson JC, Tak E, Frank S, Collins CB, Li H, Rodriguez-Aguayo C, Lopez-Berestein G, Gerich ME, Furuta GT, Yuan X, Sood AK, de Zoeten EF, Eltzschig HK. HIF-2a-dependent induction of miR-29a restrains TH1 activity during T cell dependent colitis. Nat Commun. 2024 09 14; 15(1):8042.
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Choueiri TK, Powles T, Peltola K, de Velasco G, Burotto M, Suarez C, Ghatalia P, Iacovelli R, Lam ET, Verzoni E, Gümüs M, Stadler WM, Kollmannsberger C, Melichar B, Venugopal B, Gross-Goupil M, Poprach A, De Santis M, Schutz FA, Park SH, Nosov DA, Porta C, Lee JL, Garcia-Del-Muro X, Biscaldi E, Manneh Kopp R, Oya M, He L, Wang A, Perini RF, Vickery D, Albiges L, Rini B. Belzutifan versus Everolimus for Advanced Renal-Cell Carcinoma. N Engl J Med. 2024 08 22; 391(8):710-721.
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Lemieux MR, Freigassner B, Hanson JL, Thathey Z, Opp MR, Hoeffer CA, Link CD. Multielectrode array characterization of human induced pluripotent stem cell derived neurons in co-culture with primary human astrocytes. PLoS One. 2024; 19(6):e0303901.
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Brugarolas J, Obara G, Beckermann KE, Rini B, Lam ET, Hamilton J, Schluep T, Yi M, Wong S, Mao ZL, Gamelin E, Tannir NM. A First-in-Human Phase 1 Study of a Tumor-Directed RNA-Interference Drug against HIF2a in Patients with Advanced Clear Cell Renal Cell Carcinoma. Clin Cancer Res. 2024 Jun 03; 30(11):2402-2411.
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