Receptor, Notch3
"Receptor, Notch3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A notch receptor characterized by a large extracellular domain containing 34 EPIDERMAL GROWTH FACTOR-like repeats. It functions to regulate CELL DIFFERENTIATION; APOPTOSIS; and CELL PROLIFERATION. Mutations in the EGF repeats of Notch-3 are associated with CADASIL.
Descriptor ID |
D000071656
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MeSH Number(s) |
D12.776.543.750.725.875 D12.776.930.770.875
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Concept/Terms |
Receptor, Notch3- Receptor, Notch3
- Notch-3 Protein
- Notch 3 Protein
- Notch3 Protein
- Notch-3 Receptor
- Notch 3 Receptor
- Notch3 Receptor
- Neurogenic Locus Notch Homolog Protein 3
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Below are MeSH descriptors whose meaning is more general than "Receptor, Notch3".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Notch3".
This graph shows the total number of publications written about "Receptor, Notch3" by people in this website by year, and whether "Receptor, Notch3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 | 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Notch3" by people in Profiles.
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Singh V, Akash R, Chaudhary G, Singh R, Choudhury S, Shukla A, Prabhu SN, Gangwar N, Garg SK. Sepsis downregulates aortic Notch signaling to produce vascular hyporeactivity in mice. Sci Rep. 2022 02 21; 12(1):2941.
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Ratelade J, Klug NR, Lombardi D, Angelim MKSC, Dabertrand F, Domenga-Denier V, Al-Shahi Salman R, Smith C, Gerbeau JF, Nelson MT, Joutel A. Reducing Hypermuscularization of the Transitional Segment Between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage. Circulation. 2020 06 23; 141(25):2078-2094.
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Dabertrand F, Kr?igaard C, Bonev AD, Cognat E, Dalsgaard T, Domenga-Denier V, Hill-Eubanks DC, Brayden JE, Joutel A, Nelson MT. Potassium channelopathy-like defect underlies early-stage cerebrovascular dysfunction in a genetic model of small vessel disease. Proc Natl Acad Sci U S A. 2015 Feb 17; 112(7):E796-805.
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Wang Y, Pan L, Moens CB, Appel B. Notch3 establishes brain vascular integrity by regulating pericyte number. Development. 2014 Jan; 141(2):307-17.
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Johnson J, Espinoza T, McGaughey RW, Rawls A, Wilson-Rawls J. Notch pathway genes are expressed in mammalian ovarian follicles. Mech Dev. 2001 Dec; 109(2):355-61.
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