 Genes, Homeobox
"Genes, Homeobox" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. Their sequences contain a 180 nucleotide sequence designated the homeobox, so called because mutations of these genes often results in homeotic transformations, in which one body structure replaces another. The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS.
| Descriptor ID |
D005801
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| MeSH Number(s) |
G05.360.340.024.340.230.500
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| Concept/Terms |
Genes, Homeobox- Genes, Homeobox
- Gene, Homeobox
- Homeobox Gene
- Homeobox Genes
- Genes, Homeotic
- Gene, Homeotic
- Homeotic Gene
- Hox Genes
- Gene, Hox
- Genes, Hox
- Hox Gene
- Genes, Homeo Box
- Gene, Homeo Box
- Homeo Box Gene
- Homeo Box Genes
- Homeotic Genes
Homeo Box Sequence- Homeo Box Sequence
- Homeo Box Sequences
- Sequences, Homeo Box
- Homeo Boxes
- Sequence, Homeo Box
- Homeobox Sequence
- Homeobox Sequences
- Sequence, Homeobox
- Sequences, Homeobox
- Homeoboxes
- Homeo Box
- Homeobox
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Below are MeSH descriptors whose meaning is more general than "Genes, Homeobox".
Below are MeSH descriptors whose meaning is more specific than "Genes, Homeobox".
This graph shows the total number of publications written about "Genes, Homeobox" by people in this website by year, and whether "Genes, Homeobox" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 2 | 2 | | 1995 | 1 | 1 | 2 | | 1996 | 3 | 0 | 3 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 2 | 3 | | 1999 | 2 | 0 | 2 | | 2000 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2004 | 6 | 1 | 7 | | 2006 | 1 | 2 | 3 | | 2007 | 1 | 2 | 3 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2013 | 4 | 1 | 5 | | 2017 | 0 | 1 | 1 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 | | 2022 | 0 | 2 | 2 | | 2023 | 0 | 1 | 1 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, Homeobox" by people in Profiles.
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Nguyen TT, Mitchell JM, Kiel MD, Kenny CP, Li H, Jones KL, Cornell RA, Williams TJ, Nichols JT, Van Otterloo E. TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway. Development. 2024 Jan 01; 151(1).
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Campbell AE, Arjomand J, King OD, Tawil R, Jagannathan S. A Targeted Approach for Evaluating DUX4-Regulated Proteins as Potential Serum Biomarkers for Facioscapulohumeral Muscular Dystrophy Using Immunoassay Proteomics. J Neuromuscul Dis. 2023; 10(6):1031-1040.
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Wilson C, Mertens TC, Shivshankar P, Bi W, Collum SD, Wareing N, Ko J, Weng T, Naikawadi RP, Wolters PJ, Maire P, Jyothula SS, Thandavarayan RA, Ren D, Elrod ND, Wagner EJ, Huang HJ, Dickey BF, Ford HL, Karmouty-Quintana H. Sine oculis homeobox homolog 1 plays a critical role in pulmonary fibrosis. JCI Insight. 2022 05 23; 7(10).
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Jagannathan S. The evolution of DUX4 gene regulation and its implication for facioscapulohumeral muscular dystrophy. Biochim Biophys Acta Mol Basis Dis. 2022 05 01; 1868(5):166367.
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Panfilio KA, Vargas Jentzsch IM, Benoit JB, Erezyilmaz D, Suzuki Y, Colella S, Robertson HM, Poelchau MF, Waterhouse RM, Ioannidis P, Weirauch MT, Hughes DST, Murali SC, Werren JH, Jacobs CGC, Duncan EJ, Armis?n D, Vreede BMI, Baa-Puyoulet P, Berger CS, Chang CC, Chao H, Chen MM, Chen YT, Childers CP, Chipman AD, Cridge AG, Crumi?re AJJ, Dearden PK, Didion EM, Dinh H, Doddapaneni HV, Dolan A, Dugan S, Extavour CG, Febvay G, Friedrich M, Ginzburg N, Han Y, Heger P, Holmes CJ, Horn T, Hsiao YM, Jennings EC, Johnston JS, Jones TE, Jones JW, Khila A, Koelzer S, Kovacova V, Leask M, Lee SL, Lee CY, Lovegrove MR, Lu HL, Lu Y, Moore PJ, Munoz-Torres MC, Muzny DM, Palli SR, Parisot N, Pick L, Porter ML, Qu J, Refki PN, Richter R, Rivera-Pomar R, Rosendale AJ, Roth S, Sachs L, Santos ME, Seibert J, Sghaier E, Shukla JN, Stancliffe RJ, Tidswell O, Traverso L, van der Zee M, Viala S, Worley KC, Zdobnov EM, Gibbs RA, Richards S. Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome. Genome Biol. 2019 04 02; 20(1):64.
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Parker HJ, De Kumar B, Green SA, Prummel KD, Hess C, Kaufman CK, Mosimann C, Wiedemann LM, Bronner ME, Krumlauf R. A Hox-TALE regulatory circuit for neural crest patterning is conserved across vertebrates. Nat Commun. 2019 03 13; 10(1):1189.
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Lalonde RL, Akimenko MA. Contributions of 5'HoxA/D regulation to actinodin evolution and the fin-to-limb transition. Int J Dev Biol. 2018; 62(11-12):705-716.
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Ghosh P, Sagerstr?m CG. Developing roles for Hox proteins in hindbrain gene regulatory networks. Int J Dev Biol. 2018; 62(11-12):767-774.
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Moir L, Bochukova EG, Dumbell R, Banks G, Bains RS, Nolan PM, Scudamore C, Simon M, Watson KA, Keogh J, Henning E, Hendricks A, O'Rahilly S, Barroso I, Sullivan AE, Bersten DC, Whitelaw ML, Kirsch S, Bentley E, Farooqi IS, Cox RD. Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety. Mol Metab. 2017 11; 6(11):1419-1428.
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Park S, Infante CR, Rivera-Davila LC, Menke DB. Conserved regulation of hoxc11 by pitx1 in Anolis lizards. J Exp Zool B Mol Dev Evol. 2014 May; 322(3):156-65.
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