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																		 Demyelinating Diseases
 
																		 
																		
																	 
																		 
																		
																	 
																			
																					
	"Demyelinating Diseases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
 
	
	
		
			
			
				Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
    
			 
				
				
					
						| Descriptor ID | D003711 |  
						| MeSH Number(s) | C10.314 |  
						| Concept/Terms | Demyelinating DiseasesDemyelinating DiseasesDemyelinating DiseaseDemyelinating DisordersDemyelinating Disorder
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				Below are MeSH descriptors whose meaning is more general than "Demyelinating Diseases". 
				Below are MeSH descriptors whose meaning is more specific than "Demyelinating Diseases". 
	
	
		
			
			
					
				This graph shows the total number of publications written about "Demyelinating Diseases" by people in this website by year, and whether "Demyelinating Diseases" was a major or minor topic of these publications.  
					  To see the data from this visualization as text, click here. 
		            | Year | Major Topic | Minor Topic | Total | 
|---|
 | 1995 | 1 | 0 | 1 |  | 1998 | 1 | 2 | 3 |  | 2004 | 0 | 1 | 1 |  | 2005 | 1 | 0 | 1 |  | 2006 | 4 | 2 | 6 |  | 2007 | 0 | 1 | 1 |  | 2008 | 1 | 0 | 1 |  | 2009 | 1 | 1 | 2 |  | 2011 | 0 | 1 | 1 |  | 2012 | 1 | 1 | 2 |  | 2013 | 5 | 1 | 6 |  | 2014 | 3 | 3 | 6 |  | 2015 | 2 | 1 | 3 |  | 2016 | 4 | 0 | 4 |  | 2017 | 5 | 1 | 6 |  | 2019 | 3 | 2 | 5 |  | 2020 | 1 | 2 | 3 |  | 2022 | 3 | 0 | 3 |  | 2023 | 3 | 0 | 3 |  | 2024 | 0 | 1 | 1 |  | 2025 | 2 | 1 | 3 | 
 
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				Below are the most recent publications written about "Demyelinating Diseases" by people in Profiles. 		
					
								
								Stamenkovic S, Schmid F, Gurler G, Abolmaali F, Weitermann NA, Takasaki KT, Bonney SK, Sosa MJ, Bennett HC, Kim Y, Waters J, Shih AY. Impaired capillary-venous drainage contributes to gliosis and demyelination in mouse white matter during aging. Nat Neurosci. 2025 Sep; 28(9):1868-1882.
								Gross PS, Dur?n-Laforet V, Ho LT, Melchor GS, Zia S, Manavi Z, Barclay WE, Lee SH, Shults N, Selva S, Alvarez E, Plemel JR, Fu MM, Schafer DP, Huang JK. Senescent-like microglia limit remyelination through the senescence associated secretory phenotype. Nat Commun. 2025 Mar 07; 16(1):2283.
								Della-Flora Nunes G, Osso LA, Haynes JA, Conant L, Thornton MA, Stockton ME, Brassell KA, Morris A, Mancha Corchado YI, Gaynes JA, Chavez AR, Woerner MB, MacKenna DA, Alavi A, Danks A, Poleg-Polsky A, Gandhi R, Vivian JA, Denman DJ, Hughes EG. Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function. Nat Commun. 2025 Jan 16; 16(1):732.
								Thornton MA, Futia GL, Stockton ME, Budoff SA, Ramirez AN, Ozbay B, Tzang O, Kilborn K, Poleg-Polsky A, Restrepo D, Gibson EA, Hughes EG. Long-term in vivo three-photon imaging reveals region-specific differences in healthy and regenerative oligodendrogenesis. Nat Neurosci. 2024 May; 27(5):846-861.
								Michell-Robinson MA, Watt KEN, Grouza V, Macintosh J, Pinard M, Tuznik M, Chen X, Darbelli L, Wu CL, Perrier S, Chitsaz D, Uccelli NA, Liu H, Cox TC, Müller CW, Kennedy TE, Coulombe B, Rudko DA, Trainor PA, Bernard G. Hypomyelination, hypodontia and craniofacial abnormalities in a Polr3b mouse model of leukodystrophy. Brain. 2023 12 01; 146(12):5070-5085.
								Cohen M, Thomel-Rocchi O, Siva A, Okuda DT, Karabudak R, Efendi H, Terzi M, Carra-Dalliere C, Durand-Dubief F, Thouvenot E, Ciron J, Zephir H, Bourre B, Casez O, De Seze J, Moreau T, Neau JP, Pelletier D, Kantarci O, Tutuncu M, Derache N, Bensa C, Louapre C, Benoit J, Landes-Chateau C, Lebrun-Frenay C. Impact of COVID-19 vaccination or infection on disease activity in a radiologically isolated syndrome cohort: The VaxiRIS study. Mult Scler. 2023 08; 29(9):1099-1106.
								Bhise V, Waltz M, Casper TC, Aaen G, Benson L, Chitnis T, Gorman M, Goyal MS, Wheeler Y, Lotze T, Mar S, Rensel M, Abrams A, Rodriguez M, Rose J, Schreiner T, Shukla N, Waubant E, Weinstock-Guttman B, Ness J, Krupp L, Mendelt-Tillema J. Silent findings: Examination of asymptomatic demyelination in a pediatric US cohort. Mult Scler Relat Disord. 2023 Mar; 71:104573.
								Gilani A, Kleinschmidt-DeMasters BK. Childhood Small-Vessel Primary Angiitis of the Central Nervous System: Overlap With MOG-Associated Disease. Pediatr Dev Pathol. 2023 Jan-Feb; 26(1):18-29.
								Longbrake EE, Hua LH, Mowry EM, Gauthier SA, Alvarez E, Cross AH, Pei J, Priest J, Raposo C, Hafler DA, Winger RC. The CELLO trial: Protocol of a planned phase 4 study to assess the efficacy of Ocrelizumab in patients with radiologically isolated syndrome. Mult Scler Relat Disord. 2022 Dec; 68:104143.
								Kennedy PGE, George W, Yu X. The Possible Role of Neural Cell Apoptosis in Multiple Sclerosis. Int J Mol Sci. 2022 Jul 08; 23(14). | 
																	
																		
																			
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