 Myelin Sheath
"Myelin Sheath" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.
| Descriptor ID |
D009186
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| MeSH Number(s) |
A08.637.600.500 A08.637.800.500 A08.675.542.512.560 A08.800.800.690.500 A10.755.503 A11.284.149.165.600 A11.650.600.500 A11.650.800.500 A11.671.501.512.560 A11.671.514.553
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| Concept/Terms |
Myelin Sheath- Myelin Sheath
- Myelin Sheaths
- Sheath, Myelin
- Sheaths, Myelin
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Below are MeSH descriptors whose meaning is more general than "Myelin Sheath".
Below are MeSH descriptors whose meaning is more specific than "Myelin Sheath".
This graph shows the total number of publications written about "Myelin Sheath" by people in this website by year, and whether "Myelin Sheath" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 2 | 0 | 2 | | 2005 | 2 | 3 | 5 | | 2006 | 3 | 5 | 8 | | 2007 | 1 | 0 | 1 | | 2008 | 5 | 0 | 5 | | 2009 | 0 | 1 | 1 | | 2010 | 3 | 3 | 6 | | 2011 | 4 | 2 | 6 | | 2012 | 3 | 1 | 4 | | 2013 | 5 | 0 | 5 | | 2014 | 6 | 3 | 9 | | 2015 | 7 | 2 | 9 | | 2016 | 6 | 1 | 7 | | 2017 | 7 | 1 | 8 | | 2018 | 2 | 1 | 3 | | 2019 | 6 | 1 | 7 | | 2020 | 3 | 0 | 3 | | 2021 | 5 | 2 | 7 | | 2022 | 1 | 6 | 7 | | 2023 | 1 | 4 | 5 | | 2024 | 4 | 3 | 7 | | 2025 | 5 | 2 | 7 |
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Below are the most recent publications written about "Myelin Sheath" by people in Profiles.
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Russell K, Kearns CA, Walker MB, Knoeckel CS, Ribera AB, Doll CA, Appel B. Bdnf and Ntrk2 functions promote but are not essential for spinal cord myelination in larval zebrafish. Differentiation. 2025 Sep-Oct; 145:100896.
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Given KS, Acker EG, Macklin WB, Carlin D, Owens GP, Bennett JL. Complement inhibition rapidly blocks lesion extension and facilitates remyelination in neuromyelitis optica. Acta Neuropathol Commun. 2025 06 12; 13(1):129.
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Mather ML, Evangelou AV, Bourne JN, Macklin WB, Wood TL. Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling. Glia. 2025 Sep; 73(9):1841-1859.
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Balantzategi U, Gaminde-Blasco A, Kearns CA, Bayón-Cordero L, Sánchez-Gómez MV, Zugaza JL, Appel B, Alberdi E. Amyloid-ß Dysregulates Oligodendroglial Lineage Cell Dynamics and Myelination via PKC in the Zebrafish Spinal Cord. Glia. 2025 Jul; 73(7):1437-1451.
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Gross PS, Durán-Laforet V, Ho LT, Melchor GS, Zia S, Manavi Z, Barclay WE, Lee SH, Shults N, Selva S, Alvarez E, Plemel JR, Fu MM, Schafer DP, Huang JK. Senescent-like microglia limit remyelination through the senescence associated secretory phenotype. Nat Commun. 2025 Mar 07; 16(1):2283.
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Della-Flora Nunes G, Osso LA, Haynes JA, Conant L, Thornton MA, Stockton ME, Brassell KA, Morris A, Mancha Corchado YI, Gaynes JA, Chavez AR, Woerner MB, MacKenna DA, Alavi A, Danks A, Poleg-Polsky A, Gandhi R, Vivian JA, Denman DJ, Hughes EG. Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function. Nat Commun. 2025 Jan 16; 16(1):732.
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Glaser EP, Kopper TJ, Bailey WM, Kashif HK, Kumari R, Stewart AN, Gensel JC. Cytosolic phospholipase A2 in infiltrating monocyte derived macrophages does not impair recovery after spinal cord injury in female mice. Sci Rep. 2025 01 02; 15(1):1.
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Bromley-Coolidge S, Iruegas D, Appel B. Cspg4 sculpts oligodendrocyte precursor cell morphology. Differentiation. 2024 Nov-Dec; 140:100819.
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Odell EP, Jabassini N, Schniedewind B, Pease-Raissi SE, Frymoyer A, Christians U, Green AJ, Chan JR, Ostrem BEL. Minimum effective dose of clemastine in a mouse model of preterm white matter injury. Pediatr Res. 2024 Sep; 96(4):933-941.
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Mendez Colmenares A, Thomas ML, Anderson C, Arciniegas DB, Calhoun V, Choi IY, Kramer AF, Li K, Lee J, Lee P, Burzynska AZ. Testing the structural disconnection hypothesis: Myelin content correlates with memory in healthy aging. Neurobiol Aging. 2024 09; 141:21-33.
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