 Myelin Sheath
"Myelin Sheath" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.
| Descriptor ID |
D009186
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| MeSH Number(s) |
A08.637.600.500 A08.637.800.500 A08.675.542.512.560 A08.800.800.690.500 A10.755.503 A11.284.149.165.600 A11.650.600.500 A11.650.800.500 A11.671.501.512.560 A11.671.514.553
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| Concept/Terms |
Myelin Sheath- Myelin Sheath
- Myelin Sheaths
- Sheath, Myelin
- Sheaths, Myelin
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Below are MeSH descriptors whose meaning is more general than "Myelin Sheath".
Below are MeSH descriptors whose meaning is more specific than "Myelin Sheath".
This graph shows the total number of publications written about "Myelin Sheath" by people in this website by year, and whether "Myelin Sheath" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 1 | 1 | 2 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 2 | 0 | 2 | | 2005 | 2 | 3 | 5 | | 2006 | 3 | 5 | 8 | | 2007 | 1 | 0 | 1 | | 2008 | 5 | 0 | 5 | | 2009 | 0 | 1 | 1 | | 2010 | 3 | 3 | 6 | | 2011 | 4 | 2 | 6 | | 2012 | 3 | 1 | 4 | | 2013 | 5 | 0 | 5 | | 2014 | 6 | 2 | 8 | | 2015 | 6 | 2 | 8 | | 2016 | 6 | 1 | 7 | | 2017 | 6 | 1 | 7 | | 2018 | 2 | 1 | 3 | | 2019 | 6 | 1 | 7 | | 2020 | 2 | 0 | 2 | | 2021 | 4 | 2 | 6 | | 2022 | 1 | 6 | 7 | | 2023 | 1 | 4 | 5 | | 2024 | 4 | 2 | 6 | | 2025 | 2 | 1 | 3 |
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Below are the most recent publications written about "Myelin Sheath" by people in Profiles.
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Gross PS, Dur?n-Laforet V, Ho LT, Melchor GS, Zia S, Manavi Z, Barclay WE, Lee SH, Shults N, Selva S, Alvarez E, Plemel JR, Fu MM, Schafer DP, Huang JK. Senescent-like microglia limit remyelination through the senescence associated secretory phenotype. Nat Commun. 2025 Mar 07; 16(1):2283.
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Della-Flora Nunes G, Osso LA, Haynes JA, Conant L, Thornton MA, Stockton ME, Brassell KA, Morris A, Mancha Corchado YI, Gaynes JA, Chavez AR, Woerner MB, MacKenna DA, Alavi A, Danks A, Poleg-Polsky A, Gandhi R, Vivian JA, Denman DJ, Hughes EG. Incomplete remyelination via therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function. Nat Commun. 2025 Jan 16; 16(1):732.
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Glaser EP, Kopper TJ, Bailey WM, Kashif HK, Kumari R, Stewart AN, Gensel JC. Cytosolic phospholipase A2 in infiltrating monocyte derived macrophages does not impair recovery after spinal cord injury in female mice. Sci Rep. 2025 01 02; 15(1):1.
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Bromley-Coolidge S, Iruegas D, Appel B. Cspg4 sculpts oligodendrocyte precursor cell morphology. Differentiation. 2024 Nov-Dec; 140:100819.
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Mendez Colmenares A, Thomas ML, Anderson C, Arciniegas DB, Calhoun V, Choi IY, Kramer AF, Li K, Lee J, Lee P, Burzynska AZ. Testing the structural disconnection hypothesis: Myelin content correlates with memory in healthy aging. Neurobiol Aging. 2024 Sep; 141:21-33.
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Osso LA, Hughes EG. Dynamics of mature myelin. Nat Neurosci. 2024 Aug; 27(8):1449-1461.
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Thornton MA, Futia GL, Stockton ME, Budoff SA, Ramirez AN, Ozbay B, Tzang O, Kilborn K, Poleg-Polsky A, Restrepo D, Gibson EA, Hughes EG. Long-term in vivo three-photon imaging reveals region-specific differences in healthy and regenerative oligodendrogenesis. Nat Neurosci. 2024 May; 27(5):846-861.
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Hill RA, Nishiyama A, Hughes EG. Features, Fates, and Functions of Oligodendrocyte Precursor Cells. Cold Spring Harb Perspect Biol. 2024 03 01; 16(3).
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Xiao B, Feturi F, Su AA, Van der Merwe Y, Barnett JM, Jabbari K, Khatter NJ, Li B, Katzel EB, Venkataramanan R, Solari MG, Wagner WR, Steketee MB, Simons DJ, Washington KM. Nerve Wrap for Local Delivery of FK506/Tacrolimus Accelerates Nerve Regeneration. Int J Mol Sci. 2024 Jan 10; 25(2).
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Sundaram VK, Sch?tza V, Schr?ter NH, Backhaus A, Bilsing A, Joneck L, Seelbach A, Mutschler C, Gomez-Sanchez JA, Sch?ffner E, S?nchez EE, Akkermann D, Paul C, Schwagarus N, M?ller S, Odle A, Childs G, Ewers D, Kungl T, Sitte M, Salinas G, Sereda MW, Nave KA, Schwab MH, Ost M, Arthur-Farraj P, Stassart RM, Fledrich R. Adipo-glial signaling mediates metabolic adaptation in peripheral nerve regeneration. Cell Metab. 2023 12 05; 35(12):2136-2152.e9.
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