Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution
Menu

Contact Us
If you have any questions or feedback please contact us.
 Back to Profile

Joseph Falke

Concepts (380)

Concepts are derived automatically from a person's publications.

Cloud
Categories
Timeline
Details
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Chemotaxis
43
2018
122
6.320
 Why?
Membrane Proteins
45
2018
1166
4.810
 Why?
ras Proteins
6
2026
150
4.120
 Why?
Bacterial Proteins
40
2015
968
3.830
 Why?
Receptors, Amino Acid
23
2009
25
3.470
 Why?
Signal Transduction
42
2024
5223
3.270
 Why?
Protein Kinase C-alpha
11
2023
37
2.950
 Why?
Protein Kinases
18
2014
312
2.790
 Why?
Lipid Bilayers
15
2023
103
2.640
 Why?
Cell Membrane
24
2021
709
2.570
 Why?
Disulfides
21
2014
94
2.480
 Why?
Calcium
26
2018
1191
2.380
 Why?
Escherichia coli Proteins
23
2015
201
2.270
 Why?
Phosphatidylinositol 3-Kinases
5
2022
383
2.020
 Why?
Protein Structure, Tertiary
33
2015
855
1.780
 Why?
Models, Molecular
44
2026
1599
1.670
 Why?
Salmonella typhimurium
20
2014
188
1.590
 Why?
Escherichia coli
33
2015
835
1.580
 Why?
Phosphatidylinositol Phosphates
6
2017
41
1.580
 Why?
Mutagenesis, Site-Directed
27
2014
376
1.560
 Why?
Calcium-Binding Proteins
17
2003
221
1.540
 Why?
Aspartic Acid
16
2009
88
1.500
 Why?
Cysteine
20
2009
211
1.500
 Why?
Protein Conformation
35
2016
938
1.470
 Why?
Receptors, Cytoplasmic and Nuclear
8
2013
209
1.440
 Why?
Phospholipases A
12
2007
97
1.370
 Why?
Methyl-Accepting Chemotaxis Proteins
24
2015
26
1.290
 Why?
Protein Binding
27
2026
2240
1.210
 Why?
Binding Sites
30
2026
1311
1.160
 Why?
Phosphatidylinositol 4,5-Diphosphate
7
2016
32
1.150
 Why?
Histidine Kinase
19
2015
34
1.110
 Why?
Protein Kinase C
6
2018
251
1.070
 Why?
Periplasmic Binding Proteins
9
1997
13
1.050
 Why?
Monosaccharide Transport Proteins
10
1997
56
1.040
 Why?
Kinetics
34
2014
1568
1.020
 Why?
Guanosine Triphosphate
3
2022
89
1.010
 Why?
Class Ib Phosphatidylinositol 3-Kinase
1
2026
5
0.960
 Why?
Protein Structure, Secondary
16
2013
371
0.960
 Why?
Mutation
12
2026
4090
0.880
 Why?
Proto-Oncogene Proteins p21(ras)
1
2026
254
0.870
 Why?
Macrophages
5
2020
1507
0.870
 Why?
Guanosine Diphosphate
2
2021
20
0.840
 Why?
Electron Spin Resonance Spectroscopy
8
2012
94
0.830
 Why?
Multiprotein Complexes
3
2014
172
0.820
 Why?
Calcium Signaling
5
2014
245
0.810
 Why?
Receptors, Cell Surface
13
2007
372
0.810
 Why?
Calmodulin
4
2016
70
0.800
 Why?
Myristoylated Alanine-Rich C Kinase Substrate
3
2018
6
0.800
 Why?
Protein Interaction Mapping
4
2010
105
0.790
 Why?
Intracellular Signaling Peptides and Proteins
2
2016
457
0.780
 Why?
Phosphatidylinositols
3
2022
58
0.750
 Why?
Chemoreceptor Cells
7
2007
50
0.740
 Why?
Models, Chemical
10
2013
250
0.710
 Why?
Guanine Nucleotides
1
2021
12
0.700
 Why?
Recombinant Proteins
13
2021
1368
0.690
 Why?
Cytosol
7
2007
213
0.670
 Why?
Class III Phosphatidylinositol 3-Kinases
1
2020
3
0.660
 Why?
rab5 GTP-Binding Proteins
1
2020
10
0.660
 Why?
Protein Engineering
19
2013
122
0.650
 Why?
Pseudopodia
1
2020
27
0.620
 Why?
Phosphatidylserines
6
2014
62
0.620
 Why?
Endosomes
1
2020
140
0.590
 Why?
Spin Labels
5
2008
59
0.590
 Why?
Chromatography, High Pressure Liquid
1
2021
592
0.590
 Why?
Amino Acid Substitution
11
2014
302
0.540
 Why?
Receptors, Platelet-Derived Growth Factor
1
2017
14
0.540
 Why?
Proto-Oncogene Proteins c-akt
2
2011
440
0.530
 Why?
Enzyme Activation
9
2017
762
0.520
 Why?
Conserved Sequence
3
2007
244
0.520
 Why?
Cytoplasm
6
2005
254
0.510
 Why?
Phosphatidylinositol 3-Kinase
1
2016
25
0.490
 Why?
Carrier Proteins
9
1997
729
0.490
 Why?
Biochemistry
2
2007
36
0.490
 Why?
Dimerization
8
2013
189
0.480
 Why?
Adaptor Proteins, Signal Transducing
3
2014
426
0.480
 Why?
Fluorescence Resonance Energy Transfer
4
2013
179
0.470
 Why?
Protein Interaction Domains and Motifs
3
2014
145
0.470
 Why?
Anion Exchange Protein 1, Erythrocyte
8
1986
23
0.460
 Why?
Protein Stability
2
2014
176
0.460
 Why?
Biophysics
4
2024
75
0.460
 Why?
Microscopy, Fluorescence
6
2017
408
0.440
 Why?
Cystine
1
2014
17
0.430
 Why?
Spectrometry, Fluorescence
9
2010
165
0.420
 Why?
Magnetic Resonance Spectroscopy
18
1996
627
0.410
 Why?
Eukaryotic Cells
1
2014
35
0.400
 Why?
Cell Movement
3
2020
961
0.400
 Why?
3-Phosphoinositide-Dependent Protein Kinases
1
2013
1
0.400
 Why?
Amino Acid Sequence
12
2016
2131
0.400
 Why?
Chlorides
9
1986
138
0.400
 Why?
Galactose
8
1997
34
0.370
 Why?
Lipid Metabolism
2
2007
529
0.360
 Why?
Thermotoga maritima
2
2013
12
0.350
 Why?
Membrane Lipids
2
2010
82
0.350
 Why?
Diffusion
3
2023
120
0.350
 Why?
Adaptation, Physiological
4
2020
560
0.350
 Why?
Endosomal Sorting Complexes Required for Transport
1
2012
46
0.350
 Why?
Vesicular Transport Proteins
1
2012
85
0.330
 Why?
Point Mutation
3
2009
241
0.330
 Why?
Phosphorylation
7
2021
1708
0.330
 Why?
Models, Theoretical
3
2005
560
0.330
 Why?
Amino Acid Motifs
2
2009
219
0.330
 Why?
Animals
20
2026
38097
0.320
 Why?
Protein Structure, Quaternary
2
2013
116
0.310
 Why?
Bacterial Physiological Phenomena
3
2007
47
0.300
 Why?
RAW 264.7 Cells
2
2020
48
0.290
 Why?
Bacteria
3
2014
766
0.290
 Why?
Peptide Fragments
5
2016
696
0.280
 Why?
Isoenzymes
3
2008
295
0.280
 Why?
Oncogenes
1
2008
118
0.270
 Why?
Static Electricity
6
2013
114
0.270
 Why?
Humans
37
2026
145763
0.270
 Why?
Tryptophan
5
2014
182
0.260
 Why?
Membrane Microdomains
2
2003
34
0.240
 Why?
Glycine
2
2005
186
0.230
 Why?
Cell Line
5
2018
2823
0.230
 Why?
Protein Domains
2
2017
311
0.220
 Why?
Edetic Acid
2
2003
47
0.210
 Why?
Cell Polarity
2
2020
137
0.210
 Why?
Single Molecule Imaging
1
2024
45
0.210
 Why?
Protein Kinase C beta
3
2014
21
0.200
 Why?
Cations, Divalent
4
2010
48
0.190
 Why?
Water
3
2004
447
0.190
 Why?
Spin Trapping
1
2003
3
0.190
 Why?
Hot Temperature
4
2021
396
0.190
 Why?
Surface Properties
5
2004
386
0.190
 Why?
Recombinant Fusion Proteins
4
2010
666
0.190
 Why?
Plasmids
5
2007
373
0.190
 Why?
Electrophoresis, Polyacrylamide Gel
4
2009
331
0.180
 Why?
Peptides
2
2000
998
0.180
 Why?
Phosphatidylcholines
5
2007
131
0.180
 Why?
Mice
8
2020
18355
0.180
 Why?
Molecular Dynamics Simulation
4
2014
265
0.180
 Why?
Cyclophilin A
1
2002
27
0.180
 Why?
Phosphotransferases
1
2001
26
0.180
 Why?
Receptors, G-Protein-Coupled
1
2004
231
0.170
 Why?
Chemotactic Factors
2
2007
43
0.170
 Why?
Hydrolysis
1
2021
197
0.170
 Why?
Fluorescent Dyes
4
2007
334
0.170
 Why?
Spectrophotometry, Ultraviolet
1
2021
81
0.160
 Why?
Molecular Sequence Data
6
2005
2883
0.160
 Why?
Aspartate Kinase
1
2000
1
0.160
 Why?
Metals
3
1997
136
0.160
 Why?
Intracellular Membranes
1
2020
77
0.160
 Why?
Reproducibility of Results
3
2021
3416
0.160
 Why?
Diclofenac
1
2020
14
0.160
 Why?
Time-Lapse Imaging
1
2020
21
0.160
 Why?
Glutamic Acid
3
2011
255
0.160
 Why?
Lymphocyte Antigen 96
2
2010
23
0.150
 Why?
Chelating Agents
2
1997
76
0.150
 Why?
Ibuprofen
1
2020
87
0.150
 Why?
Endocytosis
1
2020
168
0.150
 Why?
Troponin C
1
1998
3
0.140
 Why?
Alanine
2
2013
169
0.140
 Why?
Oxidation-Reduction
3
2010
1068
0.140
 Why?
Ultraviolet Rays
1
2021
385
0.140
 Why?
Membranes, Artificial
1
1998
68
0.140
 Why?
Thermodynamics
6
2002
419
0.140
 Why?
Crystallography, X-Ray
3
2013
486
0.140
 Why?
Phospholipases A2
5
2006
79
0.130
 Why?
Synaptotagmins
2
2012
22
0.130
 Why?
Phosphopeptides
1
2017
19
0.130
 Why?
Solvents
4
1999
112
0.130
 Why?
Terbium
2
1996
4
0.130
 Why?
Acetaminophen
1
2020
267
0.130
 Why?
Biophysical Phenomena
3
2010
67
0.130
 Why?
Sf9 Cells
1
2016
11
0.130
 Why?
Spodoptera
1
2016
40
0.120
 Why?
Magnesium
3
1998
157
0.120
 Why?
Aspirin
1
2020
406
0.120
 Why?
Leukocytes
1
2018
296
0.120
 Why?
Ligands
5
2010
668
0.120
 Why?
Structure-Activity Relationship
6
2013
563
0.120
 Why?
Cloning, Molecular
5
1997
538
0.120
 Why?
Fluorine Radioisotopes
1
1996
14
0.120
 Why?
Cattle
2
2008
946
0.120
 Why?
Erythrocyte Membrane
8
1986
55
0.110
 Why?
Group IV Phospholipases A2
3
2006
46
0.110
 Why?
Fluorine
5
1993
18
0.110
 Why?
Macromolecular Substances
3
2010
216
0.110
 Why?
Osmolar Concentration
3
2009
168
0.110
 Why?
Glutathione Transferase
2
2007
92
0.110
 Why?
Substrate Specificity
3
2008
387
0.110
 Why?
Protein Isoforms
2
2013
399
0.110
 Why?
Protein Transport
2
2007
442
0.110
 Why?
Hydrophobic and Hydrophilic Interactions
2
2012
192
0.110
 Why?
Microarray Analysis
1
2014
117
0.110
 Why?
Bacteriorhodopsins
2
2005
12
0.100
 Why?
Phospholipids
2
2013
214
0.100
 Why?
Hydrogen-Ion Concentration
4
2009
532
0.100
 Why?
Immunity, Innate
1
2020
835
0.100
 Why?
Protein Folding
3
2002
277
0.100
 Why?
Models, Biological
6
2007
1764
0.100
 Why?
Biological Transport, Active
7
1986
69
0.100
 Why?
Proteolysis
1
2014
172
0.100
 Why?
Histidine
2
2007
66
0.100
 Why?
Protein Denaturation
3
2002
76
0.100
 Why?
Phospholipases A2, Cytosolic
1
2013
4
0.100
 Why?
Myocardium
1
1998
935
0.100
 Why?
Protein Multimerization
1
2014
205
0.100
 Why?
Neoplasms
1
2008
2913
0.090
 Why?
Molecular Docking Simulation
1
2013
119
0.090
 Why?
Synaptotagmin I
1
2012
15
0.090
 Why?
Trypsin
1
2012
75
0.090
 Why?
Multienzyme Complexes
1
2012
65
0.090
 Why?
Nuclear Magnetic Resonance, Biomolecular
2
2007
346
0.090
 Why?
Mutagenesis
1
2013
194
0.090
 Why?
Fibroblasts
1
2018
1027
0.090
 Why?
Bacterial Outer Membrane Proteins
1
2012
62
0.090
 Why?
Molecular Structure
4
1996
487
0.090
 Why?
Computer Simulation
5
2013
1003
0.090
 Why?
Myosin-Light-Chain Kinase
1
2012
19
0.090
 Why?
Transfection
2
2011
927
0.090
 Why?
NIH 3T3 Cells
1
2011
145
0.080
 Why?
Energy Transfer
2
2002
48
0.080
 Why?
Fluoresceins
2
2003
48
0.080
 Why?
In Vitro Techniques
3
2003
1049
0.080
 Why?
Carbohydrate Metabolism
1
1991
59
0.080
 Why?
Facilitated Diffusion
1
2010
3
0.080
 Why?
Time Factors
2
2016
7133
0.080
 Why?
Toll-Like Receptor 4
2
2010
276
0.080
 Why?
Hydrodynamics
1
2010
50
0.080
 Why?
Niflumic Acid
2
1986
3
0.080
 Why?
Sequence Homology, Amino Acid
2
2004
387
0.080
 Why?
Heterocyclic Compounds, 3-Ring
1
2010
44
0.080
 Why?
Crystallization
2
2013
136
0.070
 Why?
Methyltransferases
1
2009
75
0.070
 Why?
Toll-Like Receptors
1
2010
193
0.070
 Why?
Least-Squares Analysis
1
2009
73
0.070
 Why?
Photobleaching
1
2009
24
0.070
 Why?
3T3 Cells
1
2008
156
0.070
 Why?
Cations
2
2002
83
0.070
 Why?
Hydrogen Bonding
2
2014
169
0.070
 Why?
Blood Proteins
2
2013
239
0.070
 Why?
Single-Cell Analysis
1
2011
361
0.070
 Why?
Ethylmaleimide
2
2003
18
0.070
 Why?
Phosphoproteins
2
2013
337
0.070
 Why?
Receptors, Neurotransmitter
1
1987
20
0.070
 Why?
Sensory Receptor Cells
1
1988
98
0.070
 Why?
Archaeal Proteins
1
2007
50
0.060
 Why?
Cell Survival
2
2008
1103
0.060
 Why?
Nicotinic Acids
1
1986
5
0.060
 Why?
Oligonucleotide Probes
1
2007
48
0.060
 Why?
Benzenesulfonates
1
1986
23
0.060
 Why?
Oxadiazoles
1
1986
37
0.060
 Why?
Feedback
1
2007
180
0.060
 Why?
Taurine
1
1986
41
0.060
 Why?
Lysine
1
2008
305
0.060
 Why?
Methylation
2
1997
242
0.060
 Why?
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
1
1985
9
0.060
 Why?
Structural Homology, Protein
1
2005
22
0.060
 Why?
Calcium Channel Blockers
1
1986
166
0.060
 Why?
Swine
1
2008
826
0.060
 Why?
Motion
2
1996
95
0.060
 Why?
Actins
1
2007
426
0.050
 Why?
Organometallic Compounds
2
2000
113
0.050
 Why?
Sequence Homology
1
2004
43
0.050
 Why?
Phosphatidylethanolamines
2
2002
77
0.050
 Why?
Drug Delivery Systems
1
2008
381
0.050
 Why?
Mathematics
4
1985
101
0.050
 Why?
Halobacterium
1
1984
2
0.050
 Why?
Periplasm
1
2004
13
0.050
 Why?
Membrane Potentials
1
2005
278
0.050
 Why?
Dogs
1
2005
478
0.050
 Why?
Rhodopsin
1
2004
11
0.050
 Why?
Carotenoids
1
1984
47
0.050
 Why?
Lipopolysaccharides
1
2007
858
0.050
 Why?
Analgesics, Opioid
2
2010
1154
0.050
 Why?
Computer Graphics
2
1996
41
0.050
 Why?
Rhodamines
1
2003
19
0.050
 Why?
Cyclic N-Oxides
1
2003
32
0.050
 Why?
Liposomes
2
2012
263
0.050
 Why?
Fluorescein
1
2003
24
0.050
 Why?
Data Interpretation, Statistical
1
2004
368
0.050
 Why?
Peptide Library
1
2003
91
0.050
 Why?
Sulfhydryl Compounds
2
1998
189
0.050
 Why?
Glucose
3
1992
1048
0.040
 Why?
Dansyl Compounds
1
2002
4
0.040
 Why?
Peptide Hydrolases
1
2003
105
0.040
 Why?
Urea
1
2002
85
0.040
 Why?
Nitrogen
1
2002
125
0.040
 Why?
Catalysis
1
2002
305
0.040
 Why?
Proteins
1
2007
1023
0.040
 Why?
Chlorine
3
1985
59
0.040
 Why?
Stilbenes
3
1985
30
0.040
 Why?
Arginine
1
2002
264
0.040
 Why?
Nitrilotriacetic Acid
1
2000
1
0.040
 Why?
Benzoxazoles
1
1980
20
0.040
 Why?
Chromatography, Affinity
1
2000
80
0.040
 Why?
Indicators and Reagents
1
2000
106
0.040
 Why?
Lipids
1
2005
707
0.040
 Why?
Sequence Alignment
2
1998
362
0.040
 Why?
Nickel
1
2000
62
0.040
 Why?
Staining and Labeling
1
1980
153
0.040
 Why?
Iodides
1
1998
11
0.040
 Why?
Pyrimidinones
1
1980
125
0.040
 Why?
Fluorescence Polarization
1
1998
24
0.040
 Why?
Naphthalenesulfonates
1
1998
8
0.040
 Why?
Muscles
1
1980
330
0.040
 Why?
Isotopes
2
1991
33
0.040
 Why?
Chickens
1
1998
179
0.030
 Why?
Membrane Glycoproteins
1
2001
499
0.030
 Why?
Nerve Tissue Proteins
1
2001
592
0.030
 Why?
Pain Measurement
2
2010
562
0.030
 Why?
Sequence Analysis
1
1996
34
0.030
 Why?
Solubility
1
1997
240
0.030
 Why?
Strontium
2
1998
14
0.030
 Why?
Chemistry, Physical
1
1996
37
0.030
 Why?
Chemical Phenomena
1
1996
77
0.030
 Why?
Tetrahydrofolate Dehydrogenase
1
1996
22
0.030
 Why?
Models, Structural
1
1995
41
0.030
 Why?
L-Lactate Dehydrogenase
1
1996
112
0.030
 Why?
Genetic Engineering
1
1996
88
0.030
 Why?
Flagella
1
1995
27
0.030
 Why?
Anions
2
1985
29
0.030
 Why?
Genes, Bacterial
1
1995
152
0.030
 Why?
p-Fluorophenylalanine
1
1994
2
0.030
 Why?
Glutamates
1
1994
66
0.030
 Why?
Electrons
1
2014
80
0.020
 Why?
Cations, Monovalent
1
1993
6
0.020
 Why?
Carboxylic Acids
1
1993
31
0.020
 Why?
Movement
1
1995
293
0.020
 Why?
Iodoacetamide
1
1992
5
0.020
 Why?
Cryoelectron Microscopy
1
2014
222
0.020
 Why?
Trehalose
1
2012
35
0.020
 Why?
Organophosphates
1
1993
179
0.020
 Why?
Molecular Conformation
1
1991
141
0.020
 Why?
Gadolinium
1
1991
84
0.020
 Why?
Rats
2
2010
5585
0.020
 Why?
Lac Operon
1
1990
44
0.020
 Why?
Infusion Pumps
1
2009
33
0.020
 Why?
Injections, Spinal
1
2009
120
0.020
 Why?
Toll-Like Receptor 2
1
2010
125
0.020
 Why?
Myeloid Differentiation Factor 88
1
2010
119
0.020
 Why?
Receptors, Opioid, mu
1
2009
66
0.020
 Why?
Morphine
1
2010
169
0.020
 Why?
Gene Expression Regulation, Bacterial
1
1991
337
0.020
 Why?
Hyperalgesia
1
2009
127
0.020
 Why?
Analgesia
1
2009
106
0.020
 Why?
Naloxone
1
2009
132
0.020
 Why?
Reaction Time
1
2009
434
0.020
 Why?
Microglia
1
2010
273
0.020
 Why?
Allosteric Regulation
1
1987
99
0.020
 Why?
Species Specificity
1
1988
546
0.020
 Why?
Mice, Inbred BALB C
1
2010
1261
0.020
 Why?
Narcotic Antagonists
1
2009
203
0.020
 Why?
Dinitrofluorobenzene
1
1986
4
0.020
 Why?
Substance Withdrawal Syndrome
1
2009
185
0.020
 Why?
Cyclohexanones
1
1986
9
0.020
 Why?
Cell Fractionation
1
1986
50
0.020
 Why?
Dipyridamole
1
1986
28
0.020
 Why?
Interleukin-1
1
2010
961
0.010
 Why?
Papain
1
1985
3
0.010
 Why?
Phenylglyoxal
1
1985
2
0.010
 Why?
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid
1
1985
6
0.010
 Why?
Bromine
1
1985
5
0.010
 Why?
Chymotrypsin
1
1985
23
0.010
 Why?
Sonication
1
1985
12
0.010
 Why?
Bicarbonates
1
1985
45
0.010
 Why?
Promoter Regions, Genetic
1
1990
1247
0.010
 Why?
Tumor Necrosis Factor-alpha
1
2010
1217
0.010
 Why?
Biological Transport
1
1985
424
0.010
 Why?
Halorhodopsins
1
1984
1
0.010
 Why?
Cytoskeleton
1
1985
192
0.010
 Why?
Bromides
1
1984
5
0.010
 Why?
Binding, Competitive
1
1984
185
0.010
 Why?
Radioisotopes
1
1984
37
0.010
 Why?
Muscle, Skeletal
1
1994
1791
0.010
 Why?
Cold Temperature
1
1985
206
0.010
 Why?
Rats, Sprague-Dawley
1
2009
2525
0.010
 Why?
Mice, Knockout
1
2010
3130
0.010
 Why?
Cells, Cultured
1
2010
4151
0.010
 Why?
Chick Embryo
1
1980
132
0.010
 Why?
Cell Membrane Permeability
1
1980
88
0.010
 Why?
Barium
1
1998
27
0.010
 Why?
CHO Cells
1
1998
169
0.010
 Why?
COS Cells
1
1998
177
0.010
 Why?
Cricetinae
1
1998
305
0.010
 Why?
Blood Glucose
1
1986
2344
0.010
 Why?
Male
2
2010
73003
0.010
 Why?
Cytochalasin B
1
1986
8
0.000
 Why?
Falke's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts Expand Description
See all (380) concept(s)
_
Co-Authors Expand Description
See all (5) people
_
Similar People Expand Description
See all (60) people
_
Same Department Expand Description
Search Department
Physical Neighbors Expand Description
_

Copyright © 2026 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)