Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joseph Falke

Concepts (377)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Chemotaxis
43
2018
135
8.150
Why?
Membrane Proteins
45
2018
1083
6.130
Why?
Bacterial Proteins
40
2015
770
5.230
Why?
Receptors, Amino Acid
23
2009
26
4.520
Why?
Signal Transduction
40
2021
4890
3.660
Why?
Protein Kinases
18
2014
334
3.490
Why?
Disulfides
21
2014
88
3.230
Why?
Cell Membrane
24
2021
748
3.220
Why?
Calcium
26
2018
1207
3.030
Why?
Escherichia coli Proteins
23
2015
170
3.000
Why?
Protein Kinase C-alpha
10
2016
44
2.870
Why?
Lipid Bilayers
14
2018
104
2.520
Why?
ras Proteins
3
2021
145
2.280
Why?
Protein Structure, Tertiary
33
2015
882
2.220
Why?
Escherichia coli
33
2015
795
2.060
Why?
Phosphatidylinositol Phosphates
6
2017
39
2.060
Why?
Salmonella typhimurium
20
2014
183
2.050
Why?
Calcium-Binding Proteins
17
2003
215
2.000
Why?
Mutagenesis, Site-Directed
27
2014
389
1.990
Why?
Cysteine
20
2009
204
1.970
Why?
Aspartic Acid
16
2009
89
1.950
Why?
Models, Molecular
43
2017
1547
1.900
Why?
Protein Conformation
35
2016
953
1.870
Why?
Receptors, Cytoplasmic and Nuclear
8
2013
207
1.850
Why?
Phosphatidylinositol 3-Kinases
4
2018
357
1.780
Why?
Phospholipases A
12
2007
131
1.730
Why?
Methyl-Accepting Chemotaxis Proteins
24
2015
25
1.690
Why?
Phosphatidylinositol 4,5-Diphosphate
7
2016
31
1.510
Why?
Histidine Kinase
19
2015
33
1.450
Why?
Periplasmic Binding Proteins
9
1997
14
1.370
Why?
Monosaccharide Transport Proteins
10
1997
50
1.360
Why?
Protein Kinase C
6
2018
349
1.310
Why?
Kinetics
34
2014
1759
1.270
Why?
Binding Sites
29
2013
1287
1.230
Why?
Protein Structure, Secondary
16
2013
391
1.230
Why?
Macrophages
5
2020
1315
1.180
Why?
Guanosine Diphosphate
2
2021
20
1.100
Why?
Electron Spin Resonance Spectroscopy
8
2012
83
1.080
Why?
Guanosine Triphosphate
2
2021
86
1.080
Why?
Multiprotein Complexes
3
2014
149
1.070
Why?
Protein Binding
24
2016
2053
1.060
Why?
Calcium Signaling
5
2014
226
1.050
Why?
Myristoylated Alanine-Rich C Kinase Substrate
3
2018
5
1.050
Why?
Receptors, Cell Surface
13
2007
398
1.040
Why?
Calmodulin
4
2016
82
1.030
Why?
Intracellular Signaling Peptides and Proteins
2
2016
405
1.020
Why?
Protein Interaction Mapping
4
2010
105
1.020
Why?
Chemoreceptor Cells
7
2007
55
0.950
Why?
Guanine Nucleotides
1
2021
21
0.910
Why?
Models, Chemical
10
2013
294
0.870
Why?
Class III Phosphatidylinositol 3-Kinases
1
2020
1
0.860
Why?
Recombinant Proteins
13
2021
1420
0.860
Why?
rab5 GTP-Binding Proteins
1
2020
7
0.860
Why?
Cytosol
7
2007
253
0.860
Why?
Protein Engineering
19
2013
111
0.860
Why?
Pseudopodia
1
2020
21
0.820
Why?
Phosphatidylserines
6
2014
91
0.800
Why?
Endosomes
1
2020
137
0.770
Why?
Spin Labels
5
2008
53
0.760
Why?
Chromatography, High Pressure Liquid
1
2021
540
0.760
Why?
Phosphatidylinositols
2
2020
49
0.740
Why?
Amino Acid Substitution
11
2014
286
0.710
Why?
Receptors, Platelet-Derived Growth Factor
1
2017
14
0.700
Why?
Proto-Oncogene Proteins c-akt
2
2011
457
0.680
Why?
Conserved Sequence
3
2007
218
0.670
Why?
Cytoplasm
6
2005
296
0.650
Why?
Phosphatidylinositol 3-Kinase
1
2016
23
0.650
Why?
Enzyme Activation
9
2017
956
0.640
Why?
Biochemistry
2
2007
39
0.630
Why?
Dimerization
8
2013
199
0.620
Why?
Adaptor Proteins, Signal Transducing
3
2014
387
0.610
Why?
Carrier Proteins
9
1997
808
0.610
Why?
Protein Interaction Domains and Motifs
3
2014
138
0.610
Why?
Fluorescence Resonance Energy Transfer
4
2013
188
0.610
Why?
Anion Exchange Protein 1, Erythrocyte
8
1986
23
0.600
Why?
Protein Stability
2
2014
202
0.590
Why?
Mutation
11
2021
3378
0.580
Why?
Cystine
1
2014
13
0.560
Why?
Magnetic Resonance Spectroscopy
18
1996
529
0.550
Why?
Microscopy, Fluorescence
6
2017
435
0.550
Why?
Spectrometry, Fluorescence
9
2010
183
0.540
Why?
3-Phosphoinositide-Dependent Protein Kinases
1
2013
1
0.520
Why?
Chlorides
9
1986
132
0.520
Why?
Eukaryotic Cells
1
2014
43
0.520
Why?
Cell Movement
3
2020
929
0.510
Why?
Amino Acid Sequence
12
2016
2157
0.490
Why?
Galactose
8
1997
24
0.490
Why?
Thermotoga maritima
2
2013
9
0.470
Why?
Lipid Metabolism
2
2007
526
0.460
Why?
Endosomal Sorting Complexes Required for Transport
1
2012
32
0.460
Why?
Membrane Lipids
2
2010
81
0.450
Why?
Adaptation, Physiological
4
2020
529
0.440
Why?
Vesicular Transport Proteins
1
2012
77
0.430
Why?
Point Mutation
3
2009
241
0.430
Why?
Amino Acid Motifs
2
2009
206
0.420
Why?
Phosphorylation
7
2021
1728
0.410
Why?
Protein Structure, Quaternary
2
2013
131
0.400
Why?
Models, Theoretical
3
2005
613
0.390
Why?
RAW 264.7 Cells
2
2020
44
0.380
Why?
Bacterial Physiological Phenomena
3
2007
50
0.380
Why?
Bacteria
3
2014
655
0.360
Why?
Oncogenes
1
2008
108
0.350
Why?
Tryptophan
5
2014
135
0.350
Why?
Peptide Fragments
5
2016
735
0.350
Why?
Isoenzymes
3
2008
356
0.350
Why?
Static Electricity
6
2013
116
0.340
Why?
Biophysics
3
2005
72
0.330
Why?
Membrane Microdomains
2
2003
42
0.310
Why?
Humans
35
2021
114571
0.310
Why?
Glycine
2
2005
159
0.310
Why?
Protein Domains
2
2017
210
0.300
Why?
Animals
18
2020
34687
0.300
Why?
Cell Line
5
2018
2924
0.280
Why?
Edetic Acid
2
2003
49
0.280
Why?
Cell Polarity
2
2020
131
0.270
Why?
Hot Temperature
4
2021
372
0.260
Why?
Protein Kinase C beta
3
2014
30
0.260
Why?
Cations, Divalent
4
2010
56
0.250
Why?
Spin Trapping
1
2003
2
0.250
Why?
Water
3
2004
451
0.250
Why?
Mice
8
2020
15429
0.250
Why?
Peptides
2
2000
868
0.240
Why?
Molecular Dynamics Simulation
4
2014
214
0.240
Why?
Plasmids
5
2007
385
0.240
Why?
Surface Properties
5
2004
411
0.240
Why?
Recombinant Fusion Proteins
4
2010
694
0.240
Why?
Phosphatidylcholines
5
2007
135
0.240
Why?
Electrophoresis, Polyacrylamide Gel
4
2009
362
0.240
Why?
Cyclophilin A
1
2002
25
0.230
Why?
Phosphotransferases
1
2001
33
0.230
Why?
Receptors, G-Protein-Coupled
1
2004
222
0.220
Why?
Chemotactic Factors
2
2007
51
0.220
Why?
Hydrolysis
1
2021
187
0.220
Why?
Spectrophotometry, Ultraviolet
1
2021
90
0.210
Why?
Fluorescent Dyes
4
2007
306
0.210
Why?
Diffusion
2
2013
124
0.210
Why?
Aspartate Kinase
1
2000
1
0.210
Why?
Metals
3
1997
115
0.210
Why?
Glutamic Acid
3
2011
213
0.210
Why?
Intracellular Membranes
1
2020
83
0.210
Why?
Reproducibility of Results
3
2021
2926
0.210
Why?
Diclofenac
1
2020
14
0.210
Why?
Time-Lapse Imaging
1
2020
23
0.200
Why?
Chelating Agents
2
1997
83
0.200
Why?
Lymphocyte Antigen 96
2
2010
29
0.200
Why?
Molecular Sequence Data
6
2005
3011
0.200
Why?
Endocytosis
1
2020
144
0.200
Why?
Ibuprofen
1
2020
79
0.200
Why?
Alanine
2
2013
105
0.190
Why?
Troponin C
1
1998
5
0.190
Why?
Oxidation-Reduction
3
2010
979
0.190
Why?
Membranes, Artificial
1
1998
76
0.180
Why?
Thermodynamics
6
2002
439
0.180
Why?
Phospholipases A2
5
2006
92
0.180
Why?
Crystallography, X-Ray
3
2013
468
0.170
Why?
Synaptotagmins
2
2012
18
0.170
Why?
Phosphopeptides
1
2017
18
0.170
Why?
Ultraviolet Rays
1
2021
411
0.170
Why?
Terbium
2
1996
4
0.170
Why?
Solvents
4
1999
132
0.170
Why?
Aspirin
1
2020
330
0.170
Why?
Sf9 Cells
1
2016
11
0.160
Why?
Biophysical Phenomena
3
2010
66
0.160
Why?
Spodoptera
1
2016
45
0.160
Why?
Magnesium
3
1998
157
0.160
Why?
Acetaminophen
1
2020
245
0.160
Why?
Ligands
5
2010
515
0.160
Why?
Leukocytes
1
2018
293
0.160
Why?
Structure-Activity Relationship
6
2013
553
0.150
Why?
Cloning, Molecular
5
1997
578
0.150
Why?
Fluorine Radioisotopes
1
1996
39
0.150
Why?
Fluorine
5
1993
17
0.150
Why?
Cattle
2
2008
964
0.150
Why?
Erythrocyte Membrane
8
1986
51
0.150
Why?
Macromolecular Substances
3
2010
237
0.140
Why?
Group IV Phospholipases A2
3
2006
71
0.140
Why?
Osmolar Concentration
3
2009
223
0.140
Why?
Neoplasms
1
2008
2065
0.140
Why?
Protein Isoforms
2
2013
358
0.140
Why?
Glutathione Transferase
2
2007
116
0.140
Why?
Substrate Specificity
3
2008
398
0.140
Why?
Hydrophobic and Hydrophilic Interactions
2
2012
177
0.140
Why?
Bacteriorhodopsins
2
2005
12
0.140
Why?
Microarray Analysis
1
2014
130
0.140
Why?
Protein Transport
2
2007
445
0.140
Why?
Phospholipids
2
2013
203
0.140
Why?
Hydrogen-Ion Concentration
4
2009
578
0.130
Why?
Biological Transport, Active
7
1986
75
0.130
Why?
Immunity, Innate
1
2020
741
0.130
Why?
Proteolysis
1
2014
145
0.130
Why?
Histidine
2
2007
64
0.130
Why?
Protein Folding
3
2002
310
0.130
Why?
Protein Denaturation
3
2002
118
0.130
Why?
Phospholipases A2, Cytosolic
1
2013
9
0.130
Why?
Nuclear Magnetic Resonance, Biomolecular
2
2007
240
0.130
Why?
Protein Multimerization
1
2014
167
0.130
Why?
Models, Biological
6
2007
1807
0.130
Why?
Molecular Docking Simulation
1
2013
95
0.120
Why?
Fibroblasts
1
2018
864
0.120
Why?
Synaptotagmin I
1
2012
9
0.120
Why?
Mutagenesis
1
2013
182
0.120
Why?
Trypsin
1
2012
75
0.120
Why?
Multienzyme Complexes
1
2012
68
0.120
Why?
Myocardium
1
1998
1093
0.120
Why?
Bacterial Outer Membrane Proteins
1
2012
54
0.120
Why?
Myosin-Light-Chain Kinase
1
2012
26
0.120
Why?
Molecular Structure
4
1996
493
0.120
Why?
Computer Simulation
5
2013
919
0.110
Why?
Transfection
2
2011
965
0.110
Why?
NIH 3T3 Cells
1
2011
136
0.110
Why?
Fluoresceins
2
2003
46
0.110
Why?
Energy Transfer
2
2002
57
0.110
Why?
Carbohydrate Metabolism
1
1991
59
0.110
Why?
Facilitated Diffusion
1
2010
3
0.110
Why?
Hydrodynamics
1
2010
36
0.110
Why?
In Vitro Techniques
3
2003
1229
0.100
Why?
Niflumic Acid
2
1986
3
0.100
Why?
Heterocyclic Compounds, 3-Ring
1
2010
30
0.100
Why?
Time Factors
2
2016
7029
0.100
Why?
Sequence Homology, Amino Acid
2
2004
392
0.100
Why?
Single-Cell Analysis
1
2011
194
0.100
Why?
Toll-Like Receptor 4
2
2010
381
0.100
Why?
Toll-Like Receptors
1
2010
190
0.090
Why?
Methyltransferases
1
2009
63
0.090
Why?
Photobleaching
1
2009
20
0.090
Why?
Crystallization
2
2013
158
0.090
Why?
Least-Squares Analysis
1
2009
76
0.090
Why?
3T3 Cells
1
2008
156
0.090
Why?
Cations
2
2002
77
0.090
Why?
Hydrogen Bonding
2
2014
151
0.090
Why?
Ethylmaleimide
2
2003
18
0.090
Why?
Receptors, Neurotransmitter
1
1987
13
0.090
Why?
Sensory Receptor Cells
1
1988
85
0.090
Why?
Blood Proteins
2
2013
258
0.090
Why?
Phosphoproteins
2
2013
325
0.090
Why?
Archaeal Proteins
1
2007
46
0.080
Why?
Nicotinic Acids
1
1986
6
0.080
Why?
Oligonucleotide Probes
1
2007
59
0.080
Why?
Benzenesulfonates
1
1986
23
0.080
Why?
Feedback
1
2007
146
0.080
Why?
Oxadiazoles
1
1986
33
0.080
Why?
Lysine
1
2008
232
0.080
Why?
Cell Survival
2
2008
1134
0.080
Why?
Taurine
1
1986
43
0.080
Why?
Calcium Channel Blockers
1
1986
115
0.080
Why?
Methylation
2
1997
218
0.080
Why?
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
1
1985
14
0.080
Why?
Structural Homology, Protein
1
2005
26
0.080
Why?
Swine
1
2008
725
0.070
Why?
Organometallic Compounds
2
2000
92
0.070
Why?
Actins
1
2007
367
0.070
Why?
Analgesics, Opioid
2
2010
717
0.070
Why?
Sequence Homology
1
2004
41
0.070
Why?
Motion
2
1996
97
0.070
Why?
Phosphatidylethanolamines
2
2002
65
0.070
Why?
Drug Delivery Systems
1
2008
336
0.070
Why?
Mathematics
4
1985
111
0.070
Why?
Dogs
1
2005
430
0.070
Why?
Halobacterium
1
1984
3
0.070
Why?
Periplasm
1
2004
10
0.070
Why?
Membrane Potentials
1
2005
257
0.070
Why?
Carotenoids
1
1984
31
0.070
Why?
Rhodopsin
1
2004
16
0.070
Why?
Liposomes
2
2012
169
0.070
Why?
Computer Graphics
2
1996
43
0.070
Why?
Lipopolysaccharides
1
2007
955
0.060
Why?
Rhodamines
1
2003
18
0.060
Why?
Cyclic N-Oxides
1
2003
33
0.060
Why?
Fluorescein
1
2003
23
0.060
Why?
Peptide Library
1
2003
82
0.060
Why?
Data Interpretation, Statistical
1
2004
336
0.060
Why?
Peptide Hydrolases
1
2003
99
0.060
Why?
Glucose
3
1992
905
0.060
Why?
Urea
1
2002
86
0.060
Why?
Dansyl Compounds
1
2002
6
0.060
Why?
Sulfhydryl Compounds
2
1998
180
0.060
Why?
Catalysis
1
2002
305
0.050
Why?
Arginine
1
2002
246
0.050
Why?
Nitrogen
1
2002
152
0.050
Why?
Chlorine
3
1985
55
0.050
Why?
Stilbenes
3
1985
37
0.050
Why?
Lipids
1
2005
622
0.050
Why?
Proteins
1
2007
952
0.050
Why?
Nitrilotriacetic Acid
1
2000
1
0.050
Why?
Benzoxazoles
1
1980
23
0.050
Why?
Chromatography, Affinity
1
2000
94
0.050
Why?
Indicators and Reagents
1
2000
107
0.050
Why?
Nickel
1
2000
52
0.050
Why?
Sequence Alignment
2
1998
354
0.050
Why?
Pyrimidinones
1
1980
94
0.050
Why?
Staining and Labeling
1
1980
167
0.050
Why?
Iodides
1
1998
8
0.050
Why?
Naphthalenesulfonates
1
1998
8
0.050
Why?
Fluorescence Polarization
1
1998
35
0.050
Why?
Isotopes
2
1991
21
0.050
Why?
Muscles
1
1980
331
0.050
Why?
Chickens
1
1998
181
0.040
Why?
Membrane Glycoproteins
1
2001
494
0.040
Why?
Sequence Analysis
1
1996
37
0.040
Why?
Pain Measurement
2
2010
528
0.040
Why?
Nerve Tissue Proteins
1
2001
613
0.040
Why?
Strontium
2
1998
13
0.040
Why?
Solubility
1
1997
267
0.040
Why?
Tetrahydrofolate Dehydrogenase
1
1996
14
0.040
Why?
Chemistry, Physical
1
1996
44
0.040
Why?
Chemical Phenomena
1
1996
88
0.040
Why?
Models, Structural
1
1995
43
0.040
Why?
L-Lactate Dehydrogenase
1
1996
130
0.040
Why?
Genetic Engineering
1
1996
84
0.040
Why?
Flagella
1
1995
17
0.040
Why?
Anions
2
1985
37
0.040
Why?
p-Fluorophenylalanine
1
1994
2
0.030
Why?
Genes, Bacterial
1
1995
162
0.030
Why?
Glutamates
1
1994
58
0.030
Why?
Electrons
1
2014
74
0.030
Why?
Cations, Monovalent
1
1993
5
0.030
Why?
Carboxylic Acids
1
1993
20
0.030
Why?
Cryoelectron Microscopy
1
2014
147
0.030
Why?
Iodoacetamide
1
1992
5
0.030
Why?
Trehalose
1
2012
58
0.030
Why?
Movement
1
1995
275
0.030
Why?
Organophosphates
1
1993
109
0.030
Why?
Molecular Conformation
1
1991
150
0.030
Why?
Gadolinium
1
1991
82
0.030
Why?
Lac Operon
1
1990
51
0.030
Why?
Rats
2
2010
6201
0.020
Why?
Infusion Pumps
1
2009
33
0.020
Why?
Myeloid Differentiation Factor 88
1
2010
105
0.020
Why?
Injections, Spinal
1
2009
145
0.020
Why?
Receptors, Opioid, mu
1
2009
66
0.020
Why?
Toll-Like Receptor 2
1
2010
153
0.020
Why?
Naloxone
1
2009
113
0.020
Why?
Analgesia
1
2009
98
0.020
Why?
Morphine
1
2010
192
0.020
Why?
Gene Expression Regulation, Bacterial
1
1991
298
0.020
Why?
Hyperalgesia
1
2009
187
0.020
Why?
Narcotic Antagonists
1
2009
149
0.020
Why?
Microglia
1
2010
252
0.020
Why?
Allosteric Regulation
1
1987
89
0.020
Why?
Reaction Time
1
2009
495
0.020
Why?
Substance Withdrawal Syndrome
1
2009
179
0.020
Why?
Dinitrofluorobenzene
1
1986
8
0.020
Why?
Cyclohexanones
1
1986
10
0.020
Why?
Dipyridamole
1
1986
29
0.020
Why?
Cell Fractionation
1
1986
57
0.020
Why?
Species Specificity
1
1988
617
0.020
Why?
Mice, Inbred BALB C
1
2010
1315
0.020
Why?
Phenylglyoxal
1
1985
2
0.020
Why?
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid
1
1985
9
0.020
Why?
Papain
1
1985
4
0.020
Why?
Chymotrypsin
1
1985
23
0.020
Why?
Bromine
1
1985
4
0.020
Why?
Sonication
1
1985
15
0.020
Why?
Bicarbonates
1
1985
43
0.020
Why?
Interleukin-1
1
2010
1045
0.020
Why?
Promoter Regions, Genetic
1
1990
1234
0.020
Why?
Cold Temperature
1
1985
158
0.020
Why?
Cytoskeleton
1
1985
169
0.020
Why?
Halorhodopsins
1
1984
2
0.020
Why?
Bromides
1
1984
6
0.020
Why?
Tumor Necrosis Factor-alpha
1
2010
1242
0.020
Why?
Biological Transport
1
1985
426
0.020
Why?
Muscle, Skeletal
1
1994
1534
0.020
Why?
Binding, Competitive
1
1984
212
0.020
Why?
Radioisotopes
1
1984
40
0.020
Why?
Mice, Knockout
1
2010
2835
0.020
Why?
Rats, Sprague-Dawley
1
2009
2970
0.020
Why?
Cells, Cultured
1
2010
4281
0.010
Why?
Chick Embryo
1
1980
152
0.010
Why?
Cell Membrane Permeability
1
1980
90
0.010
Why?
Barium
1
1998
26
0.010
Why?
CHO Cells
1
1998
155
0.010
Why?
COS Cells
1
1998
206
0.010
Why?
Cricetinae
1
1998
287
0.010
Why?
Blood Glucose
1
1986
1898
0.010
Why?
Male
2
2010
60817
0.010
Why?
Cytochalasin B
1
1986
18
0.000
Why?
Falke's Networks
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