Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joseph Falke

Concepts (378)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Chemotaxis
43
2018
130
6.860
Why?
Membrane Proteins
45
2018
1105
5.320
Why?
Bacterial Proteins
40
2015
823
4.410
Why?
Receptors, Amino Acid
23
2009
25
3.770
Why?
Signal Transduction
42
2024
4826
3.620
Why?
ras Proteins
5
2024
145
3.520
Why?
Protein Kinase C-alpha
11
2023
37
3.220
Why?
Protein Kinases
18
2014
309
3.000
Why?
Lipid Bilayers
15
2023
97
2.890
Why?
Cell Membrane
24
2021
720
2.780
Why?
Disulfides
21
2014
96
2.690
Why?
Calcium
26
2018
1178
2.590
Why?
Escherichia coli Proteins
23
2015
177
2.520
Why?
Phosphatidylinositol 3-Kinases
5
2022
357
2.200
Why?
Protein Structure, Tertiary
33
2015
835
1.920
Why?
Escherichia coli
33
2015
765
1.750
Why?
Salmonella typhimurium
20
2014
176
1.750
Why?
Phosphatidylinositol Phosphates
6
2017
39
1.720
Why?
Mutagenesis, Site-Directed
27
2014
358
1.690
Why?
Calcium-Binding Proteins
17
2003
210
1.680
Why?
Models, Molecular
43
2017
1480
1.650
Why?
Cysteine
20
2009
186
1.650
Why?
Aspartic Acid
16
2009
79
1.630
Why?
Protein Conformation
35
2016
852
1.620
Why?
Receptors, Cytoplasmic and Nuclear
8
2013
215
1.550
Why?
Phospholipases A
12
2007
99
1.490
Why?
Methyl-Accepting Chemotaxis Proteins
24
2015
25
1.400
Why?
Phosphatidylinositol 4,5-Diphosphate
7
2016
29
1.260
Why?
Histidine Kinase
19
2015
33
1.210
Why?
Protein Kinase C
6
2018
253
1.160
Why?
Protein Binding
26
2023
2103
1.150
Why?
Monosaccharide Transport Proteins
10
1997
49
1.140
Why?
Periplasmic Binding Proteins
9
1997
13
1.140
Why?
Guanosine Triphosphate
3
2022
92
1.100
Why?
Kinetics
34
2014
1615
1.100
Why?
Binding Sites
29
2013
1236
1.060
Why?
Protein Structure, Secondary
16
2013
338
1.050
Why?
Macrophages
5
2020
1460
0.960
Why?
Guanosine Diphosphate
2
2021
20
0.910
Why?
Electron Spin Resonance Spectroscopy
8
2012
90
0.900
Why?
Multiprotein Complexes
3
2014
147
0.900
Why?
Receptors, Cell Surface
13
2007
371
0.890
Why?
Calcium Signaling
5
2014
233
0.880
Why?
Calmodulin
4
2016
75
0.870
Why?
Myristoylated Alanine-Rich C Kinase Substrate
3
2018
6
0.870
Why?
Protein Interaction Mapping
4
2010
107
0.860
Why?
Intracellular Signaling Peptides and Proteins
2
2016
431
0.850
Why?
Phosphatidylinositols
3
2022
57
0.810
Why?
Chemoreceptor Cells
7
2007
53
0.800
Why?
Guanine Nucleotides
1
2021
15
0.760
Why?
Recombinant Proteins
13
2021
1281
0.760
Why?
Models, Chemical
10
2013
263
0.760
Why?
Cytosol
7
2007
214
0.730
Why?
Protein Engineering
19
2013
105
0.720
Why?
Class III Phosphatidylinositol 3-Kinases
1
2020
2
0.720
Why?
rab5 GTP-Binding Proteins
1
2020
6
0.720
Why?
Pseudopodia
1
2020
22
0.680
Why?
Phosphatidylserines
6
2014
88
0.670
Why?
Chromatography, High Pressure Liquid
1
2021
475
0.660
Why?
Endosomes
1
2020
126
0.650
Why?
Spin Labels
5
2008
46
0.640
Why?
Amino Acid Substitution
11
2014
281
0.590
Why?
Proto-Oncogene Proteins c-akt
2
2011
421
0.580
Why?
Receptors, Platelet-Derived Growth Factor
1
2017
14
0.580
Why?
Conserved Sequence
3
2007
227
0.560
Why?
Cytoplasm
6
2005
257
0.560
Why?
Enzyme Activation
9
2017
799
0.560
Why?
Phosphatidylinositol 3-Kinase
1
2016
26
0.540
Why?
Carrier Proteins
9
1997
732
0.530
Why?
Biochemistry
2
2007
38
0.530
Why?
Adaptor Proteins, Signal Transducing
3
2014
391
0.520
Why?
Dimerization
8
2013
188
0.520
Why?
Protein Interaction Domains and Motifs
3
2014
137
0.510
Why?
Fluorescence Resonance Energy Transfer
4
2013
177
0.510
Why?
Anion Exchange Protein 1, Erythrocyte
8
1986
22
0.500
Why?
Protein Stability
2
2014
160
0.500
Why?
Biophysics
4
2024
69
0.500
Why?
Mutation
11
2021
3689
0.490
Why?
Microscopy, Fluorescence
6
2017
399
0.470
Why?
Magnetic Resonance Spectroscopy
18
1996
508
0.470
Why?
Cystine
1
2014
17
0.470
Why?
Spectrometry, Fluorescence
9
2010
170
0.460
Why?
Eukaryotic Cells
1
2014
34
0.440
Why?
Cell Movement
3
2020
936
0.440
Why?
3-Phosphoinositide-Dependent Protein Kinases
1
2013
1
0.430
Why?
Chlorides
9
1986
138
0.430
Why?
Amino Acid Sequence
12
2016
2040
0.430
Why?
Galactose
8
1997
27
0.410
Why?
Lipid Metabolism
2
2007
491
0.400
Why?
Adaptation, Physiological
4
2020
514
0.390
Why?
Thermotoga maritima
2
2013
11
0.390
Why?
Endosomal Sorting Complexes Required for Transport
1
2012
35
0.380
Why?
Diffusion
3
2023
118
0.380
Why?
Membrane Lipids
2
2010
90
0.380
Why?
Point Mutation
3
2009
223
0.360
Why?
Vesicular Transport Proteins
1
2012
84
0.360
Why?
Amino Acid Motifs
2
2009
209
0.360
Why?
Phosphorylation
7
2021
1681
0.350
Why?
Models, Theoretical
3
2005
542
0.350
Why?
Protein Structure, Quaternary
2
2013
122
0.340
Why?
RAW 264.7 Cells
2
2020
49
0.320
Why?
Bacterial Physiological Phenomena
3
2007
58
0.310
Why?
Animals
19
2024
34479
0.310
Why?
Peptide Fragments
5
2016
684
0.300
Why?
Isoenzymes
3
2008
304
0.300
Why?
Bacteria
3
2014
808
0.300
Why?
Oncogenes
1
2008
109
0.300
Why?
Static Electricity
6
2013
117
0.290
Why?
Tryptophan
5
2014
169
0.280
Why?
Humans
36
2024
128417
0.280
Why?
Membrane Microdomains
2
2003
31
0.260
Why?
Glycine
2
2005
164
0.260
Why?
Protein Domains
2
2017
252
0.250
Why?
Cell Line
5
2018
2731
0.250
Why?
Edetic Acid
2
2003
46
0.230
Why?
Single Molecule Imaging
1
2024
35
0.230
Why?
Cell Polarity
2
2020
140
0.220
Why?
Hot Temperature
4
2021
358
0.220
Why?
Protein Kinase C beta
3
2014
21
0.210
Why?
Cations, Divalent
4
2010
54
0.210
Why?
Spin Trapping
1
2003
3
0.210
Why?
Water
3
2004
440
0.210
Why?
Recombinant Fusion Proteins
4
2010
634
0.210
Why?
Peptides
2
2000
908
0.210
Why?
Mice
8
2020
16602
0.210
Why?
Surface Properties
5
2004
393
0.200
Why?
Plasmids
5
2007
354
0.200
Why?
Electrophoresis, Polyacrylamide Gel
4
2009
323
0.200
Why?
Molecular Dynamics Simulation
4
2014
217
0.200
Why?
Phosphatidylcholines
5
2007
146
0.200
Why?
Cyclophilin A
1
2002
26
0.190
Why?
Phosphotransferases
1
2001
24
0.190
Why?
Receptors, G-Protein-Coupled
1
2004
203
0.190
Why?
Chemotactic Factors
2
2007
54
0.180
Why?
Hydrolysis
1
2021
184
0.180
Why?
Fluorescent Dyes
4
2007
311
0.180
Why?
Spectrophotometry, Ultraviolet
1
2021
80
0.180
Why?
Reproducibility of Results
3
2021
3020
0.180
Why?
Aspartate Kinase
1
2000
1
0.180
Why?
Metals
3
1997
127
0.180
Why?
Molecular Sequence Data
6
2005
2819
0.180
Why?
Intracellular Membranes
1
2020
82
0.170
Why?
Diclofenac
1
2020
14
0.170
Why?
Glutamic Acid
3
2011
230
0.170
Why?
Time-Lapse Imaging
1
2020
19
0.170
Why?
Chelating Agents
2
1997
66
0.170
Why?
Lymphocyte Antigen 96
2
2010
24
0.170
Why?
Ibuprofen
1
2020
80
0.170
Why?
Endocytosis
1
2020
161
0.160
Why?
Alanine
2
2013
141
0.160
Why?
Troponin C
1
1998
5
0.160
Why?
Oxidation-Reduction
3
2010
1001
0.150
Why?
Ultraviolet Rays
1
2021
384
0.150
Why?
Membranes, Artificial
1
1998
69
0.150
Why?
Thermodynamics
6
2002
405
0.150
Why?
Crystallography, X-Ray
3
2013
433
0.150
Why?
Phospholipases A2
5
2006
79
0.150
Why?
Phosphopeptides
1
2017
17
0.150
Why?
Synaptotagmins
2
2012
20
0.150
Why?
Acetaminophen
1
2020
243
0.140
Why?
Solvents
4
1999
107
0.140
Why?
Terbium
2
1996
4
0.140
Why?
Biophysical Phenomena
3
2010
64
0.140
Why?
Sf9 Cells
1
2016
9
0.140
Why?
Aspirin
1
2020
376
0.140
Why?
Spodoptera
1
2016
37
0.140
Why?
Magnesium
3
1998
150
0.130
Why?
Leukocytes
1
2018
303
0.130
Why?
Structure-Activity Relationship
6
2013
530
0.130
Why?
Ligands
5
2010
614
0.130
Why?
Fluorine Radioisotopes
1
1996
11
0.130
Why?
Cloning, Molecular
5
1997
522
0.130
Why?
Cattle
2
2008
960
0.130
Why?
Erythrocyte Membrane
8
1986
49
0.120
Why?
Group IV Phospholipases A2
3
2006
45
0.120
Why?
Fluorine
5
1993
15
0.120
Why?
Macromolecular Substances
3
2010
211
0.120
Why?
Osmolar Concentration
3
2009
164
0.120
Why?
Glutathione Transferase
2
2007
99
0.120
Why?
Substrate Specificity
3
2008
365
0.120
Why?
Protein Transport
2
2007
420
0.120
Why?
Hydrophobic and Hydrophilic Interactions
2
2012
184
0.120
Why?
Protein Isoforms
2
2013
378
0.120
Why?
Microarray Analysis
1
2014
120
0.110
Why?
Bacteriorhodopsins
2
2005
11
0.110
Why?
Phospholipids
2
2013
207
0.110
Why?
Hydrogen-Ion Concentration
4
2009
536
0.110
Why?
Immunity, Innate
1
2020
802
0.110
Why?
Models, Biological
6
2007
1691
0.110
Why?
Neoplasms
1
2008
2464
0.110
Why?
Biological Transport, Active
7
1986
72
0.110
Why?
Protein Folding
3
2002
265
0.110
Why?
Proteolysis
1
2014
162
0.110
Why?
Histidine
2
2007
58
0.110
Why?
Protein Denaturation
3
2002
74
0.110
Why?
Phospholipases A2, Cytosolic
1
2013
6
0.110
Why?
Nuclear Magnetic Resonance, Biomolecular
2
2007
251
0.110
Why?
Myocardium
1
1998
965
0.110
Why?
Protein Multimerization
1
2014
178
0.110
Why?
Fibroblasts
1
2018
935
0.100
Why?
Molecular Docking Simulation
1
2013
109
0.100
Why?
Mutagenesis
1
2013
181
0.100
Why?
Trypsin
1
2012
74
0.100
Why?
Synaptotagmin I
1
2012
13
0.100
Why?
Multienzyme Complexes
1
2012
68
0.100
Why?
Bacterial Outer Membrane Proteins
1
2012
58
0.100
Why?
Molecular Structure
4
1996
464
0.100
Why?
Computer Simulation
5
2013
939
0.100
Why?
Myosin-Light-Chain Kinase
1
2012
20
0.100
Why?
Transfection
2
2011
893
0.100
Why?
NIH 3T3 Cells
1
2011
141
0.090
Why?
Energy Transfer
2
2002
51
0.090
Why?
Time Factors
2
2016
6482
0.090
Why?
Fluoresceins
2
2003
47
0.090
Why?
Carbohydrate Metabolism
1
1991
60
0.090
Why?
In Vitro Techniques
3
2003
1039
0.090
Why?
Facilitated Diffusion
1
2010
3
0.090
Why?
Hydrodynamics
1
2010
40
0.090
Why?
Toll-Like Receptor 4
2
2010
262
0.090
Why?
Niflumic Acid
2
1986
3
0.090
Why?
Sequence Homology, Amino Acid
2
2004
367
0.080
Why?
Heterocyclic Compounds, 3-Ring
1
2010
31
0.080
Why?
Toll-Like Receptors
1
2010
179
0.080
Why?
Crystallization
2
2013
137
0.080
Why?
Single-Cell Analysis
1
2011
272
0.080
Why?
Photobleaching
1
2009
22
0.080
Why?
Methyltransferases
1
2009
69
0.080
Why?
Least-Squares Analysis
1
2009
72
0.080
Why?
3T3 Cells
1
2008
151
0.080
Why?
Cations
2
2002
79
0.080
Why?
Hydrogen Bonding
2
2014
149
0.070
Why?
Blood Proteins
2
2013
239
0.070
Why?
Ethylmaleimide
2
2003
18
0.070
Why?
Phosphoproteins
2
2013
327
0.070
Why?
Sensory Receptor Cells
1
1988
93
0.070
Why?
Receptors, Neurotransmitter
1
1987
16
0.070
Why?
Archaeal Proteins
1
2007
48
0.070
Why?
Cell Survival
2
2008
1077
0.070
Why?
Nicotinic Acids
1
1986
6
0.070
Why?
Oligonucleotide Probes
1
2007
50
0.070
Why?
Benzenesulfonates
1
1986
18
0.070
Why?
Feedback
1
2007
159
0.070
Why?
Oxadiazoles
1
1986
33
0.070
Why?
Taurine
1
1986
40
0.070
Why?
Lysine
1
2008
278
0.070
Why?
Calcium Channel Blockers
1
1986
123
0.060
Why?
Methylation
2
1997
227
0.060
Why?
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
1
1985
12
0.060
Why?
Structural Homology, Protein
1
2005
25
0.060
Why?
Swine
1
2008
742
0.060
Why?
Drug Delivery Systems
1
2008
325
0.060
Why?
Actins
1
2007
401
0.060
Why?
Organometallic Compounds
2
2000
105
0.060
Why?
Motion
2
1996
98
0.060
Why?
Sequence Homology
1
2004
40
0.060
Why?
Analgesics, Opioid
2
2010
887
0.060
Why?
Phosphatidylethanolamines
2
2002
74
0.060
Why?
Dogs
1
2005
366
0.060
Why?
Mathematics
4
1985
103
0.060
Why?
Halobacterium
1
1984
3
0.060
Why?
Membrane Potentials
1
2005
260
0.060
Why?
Periplasm
1
2004
11
0.060
Why?
Rhodopsin
1
2004
10
0.060
Why?
Carotenoids
1
1984
38
0.060
Why?
Liposomes
2
2012
168
0.060
Why?
Lipopolysaccharides
1
2007
856
0.060
Why?
Computer Graphics
2
1996
41
0.050
Why?
Rhodamines
1
2003
17
0.050
Why?
Cyclic N-Oxides
1
2003
30
0.050
Why?
Data Interpretation, Statistical
1
2004
335
0.050
Why?
Fluorescein
1
2003
25
0.050
Why?
Peptide Library
1
2003
83
0.050
Why?
Urea
1
2002
75
0.050
Why?
Glucose
3
1992
982
0.050
Why?
Peptide Hydrolases
1
2003
105
0.050
Why?
Dansyl Compounds
1
2002
5
0.050
Why?
Sulfhydryl Compounds
2
1998
185
0.050
Why?
Catalysis
1
2002
305
0.040
Why?
Lipids
1
2005
620
0.040
Why?
Proteins
1
2007
932
0.040
Why?
Nitrogen
1
2002
165
0.040
Why?
Chlorine
3
1985
58
0.040
Why?
Stilbenes
3
1985
36
0.040
Why?
Arginine
1
2002
258
0.040
Why?
Nitrilotriacetic Acid
1
2000
1
0.040
Why?
Benzoxazoles
1
1980
19
0.040
Why?
Chromatography, Affinity
1
2000
83
0.040
Why?
Indicators and Reagents
1
2000
105
0.040
Why?
Nickel
1
2000
54
0.040
Why?
Sequence Alignment
2
1998
329
0.040
Why?
Staining and Labeling
1
1980
137
0.040
Why?
Iodides
1
1998
6
0.040
Why?
Pyrimidinones
1
1980
101
0.040
Why?
Naphthalenesulfonates
1
1998
7
0.040
Why?
Fluorescence Polarization
1
1998
38
0.040
Why?
Isotopes
2
1991
28
0.040
Why?
Muscles
1
1980
322
0.040
Why?
Membrane Glycoproteins
1
2001
466
0.040
Why?
Chickens
1
1998
187
0.040
Why?
Pain Measurement
2
2010
487
0.030
Why?
Nerve Tissue Proteins
1
2001
567
0.030
Why?
Sequence Analysis
1
1996
37
0.030
Why?
Solubility
1
1997
229
0.030
Why?
Strontium
2
1998
14
0.030
Why?
Chemistry, Physical
1
1996
37
0.030
Why?
Chemical Phenomena
1
1996
80
0.030
Why?
Models, Structural
1
1995
40
0.030
Why?
Tetrahydrofolate Dehydrogenase
1
1996
22
0.030
Why?
L-Lactate Dehydrogenase
1
1996
116
0.030
Why?
Genetic Engineering
1
1996
88
0.030
Why?
Flagella
1
1995
19
0.030
Why?
Anions
2
1985
30
0.030
Why?
Genes, Bacterial
1
1995
158
0.030
Why?
p-Fluorophenylalanine
1
1994
2
0.030
Why?
Glutamates
1
1994
56
0.030
Why?
Electrons
1
2014
78
0.030
Why?
Cations, Monovalent
1
1993
6
0.030
Why?
Carboxylic Acids
1
1993
32
0.030
Why?
Movement
1
1995
269
0.030
Why?
Cryoelectron Microscopy
1
2014
177
0.030
Why?
Iodoacetamide
1
1992
5
0.030
Why?
Trehalose
1
2012
30
0.030
Why?
Organophosphates
1
1993
120
0.020
Why?
Rats
2
2010
5165
0.020
Why?
Gadolinium
1
1991
77
0.020
Why?
Molecular Conformation
1
1991
139
0.020
Why?
Lac Operon
1
1990
45
0.020
Why?
Infusion Pumps
1
2009
31
0.020
Why?
Toll-Like Receptor 2
1
2010
110
0.020
Why?
Myeloid Differentiation Factor 88
1
2010
95
0.020
Why?
Injections, Spinal
1
2009
106
0.020
Why?
Receptors, Opioid, mu
1
2009
56
0.020
Why?
Morphine
1
2010
126
0.020
Why?
Gene Expression Regulation, Bacterial
1
1991
322
0.020
Why?
Hyperalgesia
1
2009
108
0.020
Why?
Analgesia
1
2009
92
0.020
Why?
Naloxone
1
2009
110
0.020
Why?
Microglia
1
2010
228
0.020
Why?
Narcotic Antagonists
1
2009
160
0.020
Why?
Reaction Time
1
2009
408
0.020
Why?
Allosteric Regulation
1
1987
99
0.020
Why?
Species Specificity
1
1988
568
0.020
Why?
Mice, Inbred BALB C
1
2010
1228
0.020
Why?
Substance Withdrawal Syndrome
1
2009
169
0.020
Why?
Dinitrofluorobenzene
1
1986
7
0.020
Why?
Cyclohexanones
1
1986
9
0.020
Why?
Dipyridamole
1
1986
25
0.020
Why?
Cell Fractionation
1
1986
56
0.020
Why?
Phenylglyoxal
1
1985
1
0.020
Why?
Papain
1
1985
4
0.020
Why?
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid
1
1985
8
0.020
Why?
Interleukin-1
1
2010
961
0.020
Why?
Chymotrypsin
1
1985
19
0.020
Why?
Bromine
1
1985
6
0.020
Why?
Sonication
1
1985
13
0.020
Why?
Bicarbonates
1
1985
42
0.020
Why?
Promoter Regions, Genetic
1
1990
1198
0.020
Why?
Tumor Necrosis Factor-alpha
1
2010
1185
0.010
Why?
Biological Transport
1
1985
394
0.010
Why?
Cytoskeleton
1
1985
180
0.010
Why?
Muscle, Skeletal
1
1994
1628
0.010
Why?
Halorhodopsins
1
1984
1
0.010
Why?
Bromides
1
1984
5
0.010
Why?
Cold Temperature
1
1985
153
0.010
Why?
Radioisotopes
1
1984
31
0.010
Why?
Binding, Competitive
1
1984
199
0.010
Why?
Rats, Sprague-Dawley
1
2009
2239
0.010
Why?
Mice, Knockout
1
2010
2755
0.010
Why?
Cells, Cultured
1
2010
4001
0.010
Why?
Chick Embryo
1
1980
130
0.010
Why?
Cell Membrane Permeability
1
1980
80
0.010
Why?
Barium
1
1998
27
0.010
Why?
CHO Cells
1
1998
150
0.010
Why?
COS Cells
1
1998
184
0.010
Why?
Cricetinae
1
1998
275
0.010
Why?
Blood Glucose
1
1986
2093
0.010
Why?
Male
2
2010
62857
0.010
Why?
Cytochalasin B
1
1986
17
0.000
Why?
Falke's Networks
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