Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Joseph Falke

Concepts (380)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Chemotaxis
43
2018
123
6.350
Why?
Membrane Proteins
45
2018
1159
4.840
Why?
ras Proteins
6
2026
151
4.130
Why?
Bacterial Proteins
40
2015
981
3.850
Why?
Receptors, Amino Acid
23
2009
25
3.480
Why?
Signal Transduction
42
2024
5185
3.290
Why?
Protein Kinase C-alpha
11
2023
37
2.960
Why?
Protein Kinases
18
2014
314
2.800
Why?
Lipid Bilayers
15
2023
101
2.660
Why?
Cell Membrane
24
2021
706
2.580
Why?
Disulfides
21
2014
94
2.490
Why?
Calcium
26
2018
1182
2.400
Why?
Escherichia coli Proteins
23
2015
207
2.260
Why?
Phosphatidylinositol 3-Kinases
5
2022
380
2.030
Why?
Protein Structure, Tertiary
33
2015
849
1.790
Why?
Models, Molecular
44
2026
1610
1.670
Why?
Salmonella typhimurium
20
2014
189
1.590
Why?
Phosphatidylinositol Phosphates
6
2017
41
1.590
Why?
Mutagenesis, Site-Directed
27
2014
374
1.570
Why?
Escherichia coli
33
2015
854
1.550
Why?
Calcium-Binding Proteins
17
2003
222
1.540
Why?
Cysteine
20
2009
207
1.520
Why?
Aspartic Acid
16
2009
87
1.510
Why?
Protein Conformation
35
2016
935
1.480
Why?
Receptors, Cytoplasmic and Nuclear
8
2013
204
1.450
Why?
Phospholipases A
12
2007
97
1.380
Why?
Methyl-Accepting Chemotaxis Proteins
24
2015
26
1.290
Why?
Protein Binding
27
2026
2243
1.210
Why?
Binding Sites
30
2026
1307
1.160
Why?
Phosphatidylinositol 4,5-Diphosphate
7
2016
33
1.160
Why?
Histidine Kinase
19
2015
34
1.120
Why?
Protein Kinase C
6
2018
250
1.080
Why?
Periplasmic Binding Proteins
9
1997
13
1.050
Why?
Monosaccharide Transport Proteins
10
1997
56
1.040
Why?
Kinetics
34
2014
1602
1.020
Why?
Guanosine Triphosphate
3
2022
89
1.010
Why?
Class Ib Phosphatidylinositol 3-Kinase
1
2026
5
0.970
Why?
Protein Structure, Secondary
16
2013
365
0.970
Why?
Mutation
12
2026
4081
0.880
Why?
Macrophages
5
2020
1496
0.870
Why?
Proto-Oncogene Proteins p21(ras)
1
2026
254
0.870
Why?
Guanosine Diphosphate
2
2021
20
0.840
Why?
Electron Spin Resonance Spectroscopy
8
2012
96
0.830
Why?
Multiprotein Complexes
3
2014
171
0.830
Why?
Calcium Signaling
5
2014
243
0.820
Why?
Receptors, Cell Surface
13
2007
370
0.820
Why?
Calmodulin
4
2016
69
0.800
Why?
Myristoylated Alanine-Rich C Kinase Substrate
3
2018
6
0.800
Why?
Protein Interaction Mapping
4
2010
106
0.800
Why?
Intracellular Signaling Peptides and Proteins
2
2016
454
0.780
Why?
Phosphatidylinositols
3
2022
57
0.750
Why?
Chemoreceptor Cells
7
2007
50
0.750
Why?
Models, Chemical
10
2013
264
0.700
Why?
Guanine Nucleotides
1
2021
12
0.700
Why?
Recombinant Proteins
13
2021
1363
0.690
Why?
Cytosol
7
2007
214
0.670
Why?
Class III Phosphatidylinositol 3-Kinases
1
2020
3
0.660
Why?
rab5 GTP-Binding Proteins
1
2020
10
0.660
Why?
Protein Engineering
19
2013
122
0.660
Why?
Pseudopodia
1
2020
27
0.630
Why?
Phosphatidylserines
6
2014
60
0.630
Why?
Endosomes
1
2020
140
0.590
Why?
Chromatography, High Pressure Liquid
1
2021
580
0.590
Why?
Spin Labels
5
2008
59
0.590
Why?
Amino Acid Substitution
11
2014
303
0.550
Why?
Receptors, Platelet-Derived Growth Factor
1
2017
14
0.540
Why?
Proto-Oncogene Proteins c-akt
2
2011
435
0.530
Why?
Enzyme Activation
9
2017
762
0.520
Why?
Conserved Sequence
3
2007
247
0.520
Why?
Cytoplasm
6
2005
257
0.520
Why?
Phosphatidylinositol 3-Kinase
1
2016
24
0.500
Why?
Biochemistry
2
2007
36
0.490
Why?
Carrier Proteins
9
1997
733
0.490
Why?
Dimerization
8
2013
190
0.480
Why?
Fluorescence Resonance Energy Transfer
4
2013
177
0.480
Why?
Adaptor Proteins, Signal Transducing
3
2014
426
0.480
Why?
Protein Interaction Domains and Motifs
3
2014
146
0.470
Why?
Anion Exchange Protein 1, Erythrocyte
8
1986
23
0.460
Why?
Protein Stability
2
2014
177
0.460
Why?
Biophysics
4
2024
76
0.460
Why?
Microscopy, Fluorescence
6
2017
407
0.440
Why?
Cystine
1
2014
17
0.430
Why?
Spectrometry, Fluorescence
9
2010
159
0.430
Why?
Magnetic Resonance Spectroscopy
18
1996
625
0.420
Why?
Eukaryotic Cells
1
2014
40
0.400
Why?
Cell Movement
3
2020
959
0.400
Why?
3-Phosphoinositide-Dependent Protein Kinases
1
2013
1
0.400
Why?
Amino Acid Sequence
12
2016
2136
0.400
Why?
Chlorides
9
1986
142
0.400
Why?
Galactose
8
1997
32
0.370
Why?
Lipid Metabolism
2
2007
524
0.360
Why?
Thermotoga maritima
2
2013
12
0.360
Why?
Membrane Lipids
2
2010
82
0.350
Why?
Diffusion
3
2023
124
0.350
Why?
Endosomal Sorting Complexes Required for Transport
1
2012
46
0.350
Why?
Adaptation, Physiological
4
2020
567
0.350
Why?
Vesicular Transport Proteins
1
2012
85
0.340
Why?
Point Mutation
3
2009
242
0.330
Why?
Phosphorylation
7
2021
1704
0.330
Why?
Amino Acid Motifs
2
2009
220
0.330
Why?
Models, Theoretical
3
2005
578
0.320
Why?
Animals
20
2026
37948
0.320
Why?
Protein Structure, Quaternary
2
2013
116
0.310
Why?
RAW 264.7 Cells
2
2020
48
0.290
Why?
Bacterial Physiological Phenomena
3
2007
62
0.290
Why?
Peptide Fragments
5
2016
691
0.280
Why?
Isoenzymes
3
2008
297
0.280
Why?
Oncogenes
1
2008
118
0.270
Why?
Bacteria
3
2014
894
0.270
Why?
Humans
37
2026
144667
0.270
Why?
Static Electricity
6
2013
114
0.270
Why?
Tryptophan
5
2014
175
0.260
Why?
Membrane Microdomains
2
2003
34
0.240
Why?
Glycine
2
2005
186
0.230
Why?
Cell Line
5
2018
2821
0.230
Why?
Protein Domains
2
2017
313
0.220
Why?
Edetic Acid
2
2003
46
0.210
Why?
Cell Polarity
2
2020
137
0.210
Why?
Single Molecule Imaging
1
2024
46
0.210
Why?
Protein Kinase C beta
3
2014
21
0.200
Why?
Cations, Divalent
4
2010
47
0.200
Why?
Spin Trapping
1
2003
3
0.190
Why?
Water
3
2004
468
0.190
Why?
Hot Temperature
4
2021
410
0.190
Why?
Recombinant Fusion Proteins
4
2010
667
0.190
Why?
Surface Properties
5
2004
397
0.190
Why?
Electrophoresis, Polyacrylamide Gel
4
2009
324
0.190
Why?
Peptides
2
2000
989
0.190
Why?
Plasmids
5
2007
375
0.190
Why?
Phosphatidylcholines
5
2007
130
0.180
Why?
Mice
8
2020
18261
0.180
Why?
Molecular Dynamics Simulation
4
2014
262
0.180
Why?
Cyclophilin A
1
2002
27
0.180
Why?
Phosphotransferases
1
2001
27
0.180
Why?
Receptors, G-Protein-Coupled
1
2004
231
0.170
Why?
Chemotactic Factors
2
2007
43
0.170
Why?
Hydrolysis
1
2021
198
0.170
Why?
Fluorescent Dyes
4
2007
333
0.170
Why?
Spectrophotometry, Ultraviolet
1
2021
84
0.170
Why?
Molecular Sequence Data
6
2005
2909
0.160
Why?
Aspartate Kinase
1
2000
1
0.160
Why?
Metals
3
1997
139
0.160
Why?
Intracellular Membranes
1
2020
76
0.160
Why?
Reproducibility of Results
3
2021
3414
0.160
Why?
Diclofenac
1
2020
14
0.160
Why?
Glutamic Acid
3
2011
254
0.160
Why?
Time-Lapse Imaging
1
2020
22
0.160
Why?
Lymphocyte Antigen 96
2
2010
24
0.150
Why?
Ibuprofen
1
2020
84
0.150
Why?
Chelating Agents
2
1997
72
0.150
Why?
Endocytosis
1
2020
167
0.150
Why?
Troponin C
1
1998
3
0.140
Why?
Alanine
2
2013
170
0.140
Why?
Ultraviolet Rays
1
2021
384
0.140
Why?
Oxidation-Reduction
3
2010
1078
0.140
Why?
Membranes, Artificial
1
1998
73
0.140
Why?
Thermodynamics
6
2002
425
0.140
Why?
Crystallography, X-Ray
3
2013
491
0.140
Why?
Phospholipases A2
5
2006
79
0.140
Why?
Synaptotagmins
2
2012
22
0.130
Why?
Phosphopeptides
1
2017
19
0.130
Why?
Solvents
4
1999
113
0.130
Why?
Terbium
2
1996
4
0.130
Why?
Acetaminophen
1
2020
265
0.130
Why?
Biophysical Phenomena
3
2010
68
0.130
Why?
Sf9 Cells
1
2016
11
0.130
Why?
Spodoptera
1
2016
40
0.120
Why?
Magnesium
3
1998
155
0.120
Why?
Aspirin
1
2020
402
0.120
Why?
Leukocytes
1
2018
294
0.120
Why?
Ligands
5
2010
662
0.120
Why?
Structure-Activity Relationship
6
2013
564
0.120
Why?
Cloning, Molecular
5
1997
535
0.120
Why?
Fluorine Radioisotopes
1
1996
14
0.120
Why?
Cattle
2
2008
975
0.120
Why?
Erythrocyte Membrane
8
1986
54
0.110
Why?
Group IV Phospholipases A2
3
2006
46
0.110
Why?
Fluorine
5
1993
17
0.110
Why?
Macromolecular Substances
3
2010
219
0.110
Why?
Osmolar Concentration
3
2009
169
0.110
Why?
Glutathione Transferase
2
2007
96
0.110
Why?
Substrate Specificity
3
2008
392
0.110
Why?
Protein Isoforms
2
2013
396
0.110
Why?
Protein Transport
2
2007
437
0.110
Why?
Hydrophobic and Hydrophilic Interactions
2
2012
187
0.110
Why?
Microarray Analysis
1
2014
116
0.110
Why?
Bacteriorhodopsins
2
2005
12
0.110
Why?
Phospholipids
2
2013
214
0.100
Why?
Hydrogen-Ion Concentration
4
2009
562
0.100
Why?
Immunity, Innate
1
2020
843
0.100
Why?
Protein Folding
3
2002
277
0.100
Why?
Biological Transport, Active
7
1986
69
0.100
Why?
Proteolysis
1
2014
170
0.100
Why?
Models, Biological
6
2007
1811
0.100
Why?
Histidine
2
2007
65
0.100
Why?
Protein Denaturation
3
2002
71
0.100
Why?
Phospholipases A2, Cytosolic
1
2013
6
0.100
Why?
Myocardium
1
1998
928
0.100
Why?
Protein Multimerization
1
2014
207
0.100
Why?
Neoplasms
1
2008
2873
0.100
Why?
Molecular Docking Simulation
1
2013
121
0.090
Why?
Synaptotagmin I
1
2012
15
0.090
Why?
Trypsin
1
2012
75
0.090
Why?
Multienzyme Complexes
1
2012
65
0.090
Why?
Nuclear Magnetic Resonance, Biomolecular
2
2007
346
0.090
Why?
Mutagenesis
1
2013
194
0.090
Why?
Fibroblasts
1
2018
1019
0.090
Why?
Bacterial Outer Membrane Proteins
1
2012
61
0.090
Why?
Molecular Structure
4
1996
495
0.090
Why?
Myosin-Light-Chain Kinase
1
2012
19
0.090
Why?
Computer Simulation
5
2013
1021
0.090
Why?
Transfection
2
2011
924
0.090
Why?
NIH 3T3 Cells
1
2011
147
0.090
Why?
Energy Transfer
2
2002
48
0.090
Why?
Fluoresceins
2
2003
48
0.080
Why?
In Vitro Techniques
3
2003
1046
0.080
Why?
Carbohydrate Metabolism
1
1991
58
0.080
Why?
Facilitated Diffusion
1
2010
3
0.080
Why?
Time Factors
2
2016
7140
0.080
Why?
Toll-Like Receptor 4
2
2010
277
0.080
Why?
Hydrodynamics
1
2010
51
0.080
Why?
Niflumic Acid
2
1986
3
0.080
Why?
Sequence Homology, Amino Acid
2
2004
393
0.080
Why?
Heterocyclic Compounds, 3-Ring
1
2010
44
0.080
Why?
Crystallization
2
2013
140
0.070
Why?
Methyltransferases
1
2009
75
0.070
Why?
Toll-Like Receptors
1
2010
193
0.070
Why?
Least-Squares Analysis
1
2009
74
0.070
Why?
Photobleaching
1
2009
23
0.070
Why?
3T3 Cells
1
2008
156
0.070
Why?
Cations
2
2002
82
0.070
Why?
Hydrogen Bonding
2
2014
169
0.070
Why?
Blood Proteins
2
2013
230
0.070
Why?
Single-Cell Analysis
1
2011
357
0.070
Why?
Ethylmaleimide
2
2003
18
0.070
Why?
Phosphoproteins
2
2013
339
0.070
Why?
Receptors, Neurotransmitter
1
1987
20
0.070
Why?
Sensory Receptor Cells
1
1988
98
0.070
Why?
Archaeal Proteins
1
2007
51
0.060
Why?
Cell Survival
2
2008
1092
0.060
Why?
Nicotinic Acids
1
1986
5
0.060
Why?
Oligonucleotide Probes
1
2007
48
0.060
Why?
Benzenesulfonates
1
1986
22
0.060
Why?
Oxadiazoles
1
1986
37
0.060
Why?
Feedback
1
2007
181
0.060
Why?
Lysine
1
2008
271
0.060
Why?
Taurine
1
1986
41
0.060
Why?
Methylation
2
1997
241
0.060
Why?
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
1
1985
9
0.060
Why?
Structural Homology, Protein
1
2005
23
0.060
Why?
Calcium Channel Blockers
1
1986
165
0.060
Why?
Swine
1
2008
828
0.060
Why?
Motion
2
1996
99
0.060
Why?
Actins
1
2007
421
0.060
Why?
Organometallic Compounds
2
2000
113
0.060
Why?
Sequence Homology
1
2004
44
0.050
Why?
Phosphatidylethanolamines
2
2002
76
0.050
Why?
Drug Delivery Systems
1
2008
380
0.050
Why?
Mathematics
4
1985
100
0.050
Why?
Halobacterium
1
1984
3
0.050
Why?
Dogs
1
2005
438
0.050
Why?
Periplasm
1
2004
13
0.050
Why?
Membrane Potentials
1
2005
278
0.050
Why?
Rhodopsin
1
2004
11
0.050
Why?
Carotenoids
1
1984
48
0.050
Why?
Analgesics, Opioid
2
2010
1142
0.050
Why?
Lipopolysaccharides
1
2007
854
0.050
Why?
Computer Graphics
2
1996
41
0.050
Why?
Rhodamines
1
2003
21
0.050
Why?
Liposomes
2
2012
256
0.050
Why?
Cyclic N-Oxides
1
2003
32
0.050
Why?
Fluorescein
1
2003
24
0.050
Why?
Data Interpretation, Statistical
1
2004
368
0.050
Why?
Peptide Library
1
2003
91
0.050
Why?
Sulfhydryl Compounds
2
1998
188
0.050
Why?
Glucose
3
1992
1033
0.050
Why?
Dansyl Compounds
1
2002
4
0.050
Why?
Peptide Hydrolases
1
2003
105
0.040
Why?
Urea
1
2002
84
0.040
Why?
Catalysis
1
2002
319
0.040
Why?
Nitrogen
1
2002
170
0.040
Why?
Arginine
1
2002
238
0.040
Why?
Chlorine
3
1985
62
0.040
Why?
Proteins
1
2007
1016
0.040
Why?
Stilbenes
3
1985
33
0.040
Why?
Nitrilotriacetic Acid
1
2000
1
0.040
Why?
Benzoxazoles
1
1980
19
0.040
Why?
Chromatography, Affinity
1
2000
80
0.040
Why?
Indicators and Reagents
1
2000
106
0.040
Why?
Lipids
1
2005
706
0.040
Why?
Sequence Alignment
2
1998
371
0.040
Why?
Nickel
1
2000
62
0.040
Why?
Staining and Labeling
1
1980
153
0.040
Why?
Iodides
1
1998
10
0.040
Why?
Pyrimidinones
1
1980
125
0.040
Why?
Fluorescence Polarization
1
1998
24
0.040
Why?
Naphthalenesulfonates
1
1998
8
0.040
Why?
Isotopes
2
1991
34
0.040
Why?
Muscles
1
1980
332
0.040
Why?
Chickens
1
1998
184
0.030
Why?
Membrane Glycoproteins
1
2001
496
0.030
Why?
Pain Measurement
2
2010
554
0.030
Why?
Nerve Tissue Proteins
1
2001
590
0.030
Why?
Sequence Analysis
1
1996
35
0.030
Why?
Solubility
1
1997
236
0.030
Why?
Strontium
2
1998
14
0.030
Why?
Chemistry, Physical
1
1996
39
0.030
Why?
Chemical Phenomena
1
1996
81
0.030
Why?
Models, Structural
1
1995
41
0.030
Why?
Tetrahydrofolate Dehydrogenase
1
1996
23
0.030
Why?
L-Lactate Dehydrogenase
1
1996
113
0.030
Why?
Genetic Engineering
1
1996
89
0.030
Why?
Flagella
1
1995
28
0.030
Why?
Anions
2
1985
31
0.030
Why?
Genes, Bacterial
1
1995
170
0.030
Why?
p-Fluorophenylalanine
1
1994
2
0.030
Why?
Glutamates
1
1994
66
0.030
Why?
Electrons
1
2014
88
0.020
Why?
Cations, Monovalent
1
1993
6
0.020
Why?
Carboxylic Acids
1
1993
33
0.020
Why?
Movement
1
1995
295
0.020
Why?
Iodoacetamide
1
1992
5
0.020
Why?
Cryoelectron Microscopy
1
2014
220
0.020
Why?
Trehalose
1
2012
35
0.020
Why?
Organophosphates
1
1993
179
0.020
Why?
Gadolinium
1
1991
84
0.020
Why?
Molecular Conformation
1
1991
147
0.020
Why?
Rats
2
2010
5570
0.020
Why?
Lac Operon
1
1990
44
0.020
Why?
Infusion Pumps
1
2009
33
0.020
Why?
Injections, Spinal
1
2009
120
0.020
Why?
Myeloid Differentiation Factor 88
1
2010
117
0.020
Why?
Toll-Like Receptor 2
1
2010
127
0.020
Why?
Receptors, Opioid, mu
1
2009
66
0.020
Why?
Morphine
1
2010
169
0.020
Why?
Gene Expression Regulation, Bacterial
1
1991
344
0.020
Why?
Analgesia
1
2009
105
0.020
Why?
Hyperalgesia
1
2009
132
0.020
Why?
Naloxone
1
2009
131
0.020
Why?
Microglia
1
2010
269
0.020
Why?
Reaction Time
1
2009
438
0.020
Why?
Allosteric Regulation
1
1987
98
0.020
Why?
Species Specificity
1
1988
573
0.020
Why?
Mice, Inbred BALB C
1
2010
1251
0.020
Why?
Dinitrofluorobenzene
1
1986
4
0.020
Why?
Narcotic Antagonists
1
2009
204
0.020
Why?
Cyclohexanones
1
1986
9
0.020
Why?
Substance Withdrawal Syndrome
1
2009
187
0.020
Why?
Cell Fractionation
1
1986
49
0.020
Why?
Dipyridamole
1
1986
28
0.020
Why?
Interleukin-1
1
2010
961
0.010
Why?
Papain
1
1985
3
0.010
Why?
Phenylglyoxal
1
1985
2
0.010
Why?
4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid
1
1985
6
0.010
Why?
Chymotrypsin
1
1985
23
0.010
Why?
Bromine
1
1985
6
0.010
Why?
Sonication
1
1985
12
0.010
Why?
Bicarbonates
1
1985
45
0.010
Why?
Promoter Regions, Genetic
1
1990
1246
0.010
Why?
Tumor Necrosis Factor-alpha
1
2010
1207
0.010
Why?
Biological Transport
1
1985
418
0.010
Why?
Halorhodopsins
1
1984
1
0.010
Why?
Bromides
1
1984
5
0.010
Why?
Cytoskeleton
1
1985
197
0.010
Why?
Binding, Competitive
1
1984
182
0.010
Why?
Radioisotopes
1
1984
37
0.010
Why?
Muscle, Skeletal
1
1994
1788
0.010
Why?
Cold Temperature
1
1985
208
0.010
Why?
Rats, Sprague-Dawley
1
2009
2521
0.010
Why?
Mice, Knockout
1
2010
3109
0.010
Why?
Cells, Cultured
1
2010
4110
0.010
Why?
Chick Embryo
1
1980
132
0.010
Why?
Cell Membrane Permeability
1
1980
87
0.010
Why?
Barium
1
1998
27
0.010
Why?
CHO Cells
1
1998
165
0.010
Why?
COS Cells
1
1998
177
0.010
Why?
Cricetinae
1
1998
296
0.010
Why?
Blood Glucose
1
1986
2326
0.010
Why?
Male
2
2010
72431
0.010
Why?
Cytochalasin B
1
1986
8
0.000
Why?
Falke's Networks
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