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Colin Shearn

Concepts (298)

Concepts are derived automatically from a person's publications.

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Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Cholestasis
10
2023
232
3.740
 Why?
Aldehydes
15
2022
143
3.420
 Why?
Liver
22
2025
1839
3.050
 Why?
Protein Carbonylation
10
2018
56
2.670
 Why?
PTEN Phosphohydrolase
7
2018
161
2.640
 Why?
Liver Diseases, Alcoholic
12
2019
89
2.610
 Why?
Bile Acids and Salts
7
2024
195
2.270
 Why?
Ethanol
12
2019
589
1.910
 Why?
Antioxidants
7
2023
559
1.760
 Why?
Glutathione Transferase
8
2019
101
1.740
 Why?
Cholangitis, Sclerosing
4
2024
71
1.690
 Why?
Parenteral Nutrition
5
2024
104
1.430
 Why?
Proto-Oncogene Proteins c-akt
6
2016
431
1.430
 Why?
Oxidative Stress
14
2019
1269
1.270
 Why?
Fatty Liver
3
2014
231
1.090
 Why?
Ileum
2
2024
116
1.080
 Why?
Mice, Inbred C57BL
17
2025
5440
1.020
 Why?
Tumor Necrosis Factor-alpha
5
2024
1198
0.980
 Why?
Inflammatory Bowel Diseases
3
2020
320
0.980
 Why?
Mice
37
2025
16937
0.960
 Why?
Fatty Liver, Alcoholic
2
2016
16
0.940
 Why?
Signal Transduction
11
2024
4925
0.910
 Why?
Thioredoxins
3
2018
28
0.880
 Why?
Carcinoma, Hepatocellular
3
2019
272
0.850
 Why?
Abdominal Injuries
1
2023
118
0.770
 Why?
AMP-Activated Protein Kinases
2
2014
191
0.770
 Why?
Animals
39
2025
35361
0.720
 Why?
Protein Processing, Post-Translational
4
2016
455
0.710
 Why?
Circadian Rhythm
1
2024
413
0.710
 Why?
Butylated Hydroxytoluene
2
2011
38
0.660
 Why?
Disease Models, Animal
13
2025
4063
0.650
 Why?
Hepatocytes
5
2021
216
0.630
 Why?
Peroxiredoxins
2
2018
24
0.630
 Why?
NF-E2-Related Factor 2
2
2019
79
0.600
 Why?
Thioredoxin-Disulfide Reductase
1
2018
13
0.600
 Why?
Non-alcoholic Fatty Liver Disease
3
2017
261
0.580
 Why?
Liver Neoplasms
4
2019
640
0.580
 Why?
Gene Knockout Techniques
1
2018
109
0.570
 Why?
Liver Diseases
2
2021
290
0.560
 Why?
Hepatitis
1
2017
47
0.560
 Why?
Liver Cirrhosis
3
2024
280
0.540
 Why?
Receptors, Cytoplasmic and Nuclear
3
2024
217
0.530
 Why?
Mitochondrial Proteins
2
2015
248
0.520
 Why?
Superoxide Dismutase
5
2019
342
0.520
 Why?
Chemical and Drug Induced Liver Injury, Chronic
1
2016
11
0.520
 Why?
End Stage Liver Disease
1
2017
78
0.510
 Why?
Thioredoxin Reductase 1
3
2023
8
0.510
 Why?
Liver Cirrhosis, Alcoholic
1
2015
17
0.500
 Why?
Tandem Mass Spectrometry
5
2022
524
0.470
 Why?
Alcoholism
3
2018
766
0.460
 Why?
ARNTL Transcription Factors
2
2024
16
0.450
 Why?
Oxidants
2
2012
109
0.440
 Why?
Diet, High-Fat
2
2016
239
0.430
 Why?
Male
30
2025
63681
0.430
 Why?
Mice, Knockout
8
2020
2871
0.420
 Why?
Dietary Fats
2
2018
301
0.390
 Why?
RNA, Messenger
6
2023
2708
0.380
 Why?
Lipid Peroxidation
4
2016
151
0.370
 Why?
Xenobiotics
1
2011
29
0.360
 Why?
Hydrogen Peroxide
1
2012
318
0.340
 Why?
Chromatography, Liquid
4
2017
423
0.340
 Why?
Oxidoreductases Acting on CH-CH Group Donors
1
2010
23
0.340
 Why?
Cell Proliferation
3
2018
2391
0.330
 Why?
Glutathione Reductase
3
2019
24
0.330
 Why?
Alcohol Drinking
1
2016
764
0.320
 Why?
Inflammation
5
2023
2736
0.320
 Why?
Mitochondria
4
2019
877
0.320
 Why?
Down-Regulation
1
2011
636
0.300
 Why?
Blotting, Western
4
2016
1205
0.300
 Why?
Carcinoma
1
2010
217
0.290
 Why?
Autophagy
2
2022
268
0.290
 Why?
Alcohol Oxidoreductases
1
2008
60
0.290
 Why?
Carcinogens
1
2008
110
0.290
 Why?
Colonic Neoplasms
1
2010
243
0.280
 Why?
Catalase
2
2017
129
0.280
 Why?
Phosphoric Monoester Hydrolases
1
2007
54
0.270
 Why?
NF-kappa B
2
2021
653
0.260
 Why?
Glutathione
4
2019
348
0.250
 Why?
Hep G2 Cells
3
2021
61
0.250
 Why?
Alanine Transaminase
3
2016
153
0.250
 Why?
Up-Regulation
2
2019
840
0.240
 Why?
Case-Control Studies
3
2018
3381
0.240
 Why?
Protein Kinase Inhibitors
1
2011
891
0.240
 Why?
Recombinant Proteins
4
2020
1304
0.240
 Why?
Gene Expression Regulation
5
2021
2548
0.230
 Why?
Humans
27
2023
129650
0.230
 Why?
Enzyme Inhibitors
1
2008
827
0.230
 Why?
Macrophage Activation
2
2023
189
0.230
 Why?
Ileitis
1
2024
33
0.230
 Why?
Biomarkers
1
2015
3973
0.220
 Why?
Proteomics
4
2019
1062
0.220
 Why?
Phosphorylation
3
2014
1713
0.220
 Why?
Lipoproteins
2
2021
171
0.220
 Why?
Epithelial Cells
1
2010
1065
0.220
 Why?
Genes, Regulator
1
2023
34
0.210
 Why?
Fibroblast Growth Factors
1
2024
170
0.210
 Why?
Cysteine Proteinase Inhibitors
2
2014
50
0.210
 Why?
Biliary Atresia
1
2025
161
0.210
 Why?
Sulfhydryl Compounds
2
2018
187
0.200
 Why?
Insulin Resistance
1
2011
1165
0.200
 Why?
Prostatic Neoplasms
1
2010
1016
0.200
 Why?
Fatty Acid-Binding Proteins
2
2013
69
0.200
 Why?
Enzyme Activation
3
2013
811
0.190
 Why?
Triglycerides
2
2016
527
0.190
 Why?
Mitochondria, Liver
2
2013
74
0.190
 Why?
Dioxanes
1
2021
7
0.190
 Why?
Isoxazoles
1
2021
55
0.190
 Why?
NLR Family, Pyrin Domain-Containing 3 Protein
1
2023
149
0.190
 Why?
Phytosterols
1
2021
12
0.190
 Why?
Oxidation-Reduction
3
2019
1033
0.180
 Why?
Models, Molecular
4
2014
1492
0.180
 Why?
Mucoproteins
1
2020
10
0.180
 Why?
Cholesterol
2
2020
412
0.180
 Why?
Phosphatidylinositol 4,5-Diphosphate
1
2020
31
0.170
 Why?
Vesicular Transport Proteins
1
2020
84
0.170
 Why?
Phosphatidylcholines
1
2020
146
0.160
 Why?
Macrophages
2
2025
1480
0.160
 Why?
Gene Expression
2
2021
1472
0.160
 Why?
Liposomes
1
2020
168
0.160
 Why?
Cell Adhesion Molecules
1
2020
173
0.160
 Why?
Acylation
1
2019
28
0.160
 Why?
Lysosomes
1
2019
138
0.150
 Why?
Chromatography, High Pressure Liquid
2
2013
582
0.150
 Why?
Female
10
2025
68776
0.150
 Why?
PPAR alpha
2
2016
58
0.150
 Why?
Colon
1
2020
254
0.150
 Why?
Mice, 129 Strain
1
2018
87
0.150
 Why?
Ribosomes
1
2019
164
0.150
 Why?
Heme Oxygenase-1
1
2018
62
0.150
 Why?
Lung
1
2011
3930
0.150
 Why?
Sulfinic Acids
1
2018
8
0.150
 Why?
Colitis
1
2020
242
0.140
 Why?
Aminobutyrates
1
2018
33
0.140
 Why?
Azo Compounds
1
2017
26
0.140
 Why?
Reactive Oxygen Species
2
2011
596
0.140
 Why?
Taurine
1
2018
43
0.140
 Why?
Pyruvaldehyde
1
2018
43
0.140
 Why?
Organ Specificity
1
2018
296
0.140
 Why?
HSP70 Heat-Shock Proteins
1
2017
69
0.140
 Why?
Protein Structure, Secondary
1
2018
341
0.140
 Why?
Gene Deletion
2
2015
379
0.140
 Why?
Homocystinuria
1
2018
70
0.140
 Why?
Malnutrition
1
2018
79
0.130
 Why?
Mice, Inbred BALB C
2
2011
1245
0.130
 Why?
Middle Aged
4
2019
31154
0.130
 Why?
Amino Acid Sequence
4
2015
2058
0.130
 Why?
Cell Line, Tumor
3
2020
3215
0.130
 Why?
Lipogenesis
1
2016
59
0.120
 Why?
Fatty Acids, Unsaturated
1
2016
97
0.120
 Why?
Sirtuin 3
2
2019
58
0.120
 Why?
Lysine
1
2017
286
0.120
 Why?
Adult
4
2019
35576
0.120
 Why?
Cytochrome P-450 CYP4A
1
2014
4
0.110
 Why?
Acetylation
4
2017
246
0.110
 Why?
Proteome
1
2019
443
0.110
 Why?
CD36 Antigens
1
2014
36
0.110
 Why?
Protein Isoforms
1
2015
391
0.110
 Why?
Endoplasmic Reticulum Stress
1
2014
101
0.110
 Why?
Central Nervous System Depressants
1
2014
82
0.110
 Why?
Heat-Shock Proteins
1
2014
136
0.110
 Why?
Protein Binding
4
2020
2121
0.110
 Why?
Phosphatidylinositol 3-Kinases
2
2013
359
0.110
 Why?
DNA Primers
2
2012
510
0.110
 Why?
Carrier Proteins
1
2017
743
0.110
 Why?
Adenosine Triphosphatases
1
2014
161
0.110
 Why?
Acetyl-CoA Carboxylase
1
2013
33
0.100
 Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
1
2013
24
0.100
 Why?
Molecular Sequence Data
3
2015
2832
0.100
 Why?
Computational Biology
1
2017
599
0.100
 Why?
Sterol Regulatory Element Binding Protein 1
1
2013
57
0.100
 Why?
Polymerase Chain Reaction
2
2016
1038
0.100
 Why?
Models, Chemical
1
2014
265
0.100
 Why?
Endoplasmic Reticulum
2
2014
261
0.100
 Why?
Organ Size
1
2013
447
0.100
 Why?
Reactive Nitrogen Species
1
2011
22
0.090
 Why?
Peptide Mapping
1
2011
63
0.090
 Why?
Glycogen Synthase Kinase 3 beta
1
2011
68
0.090
 Why?
Adiponectin
1
2013
235
0.090
 Why?
Binding Sites
2
2020
1252
0.090
 Why?
Glycogen Synthase Kinase 3
1
2011
79
0.090
 Why?
Crotonates
1
2010
5
0.090
 Why?
Toluidines
1
2010
7
0.090
 Why?
Hydroxybutyrates
1
2010
14
0.090
 Why?
Receptors, Estrogen
1
2013
426
0.090
 Why?
Fenretinide
1
2010
7
0.090
 Why?
Tumor Cells, Cultured
1
2012
940
0.080
 Why?
Oxygen Consumption
1
2013
672
0.080
 Why?
Cell Line, Transformed
1
2010
141
0.080
 Why?
Microscopy, Confocal
1
2011
310
0.080
 Why?
Fluorescence Resonance Energy Transfer
1
2011
177
0.080
 Why?
Protein Conformation
1
2012
859
0.080
 Why?
Nitriles
1
2010
172
0.080
 Why?
Glycoproteins
1
2011
338
0.080
 Why?
Cell Survival
1
2012
1086
0.080
 Why?
Alkylation
1
2008
25
0.080
 Why?
Nuclear Proteins
1
2013
663
0.070
 Why?
DNA Damage
2
2021
384
0.070
 Why?
RNA, Small Interfering
1
2010
587
0.070
 Why?
Cytosol
1
2008
218
0.070
 Why?
Spectrometry, Mass, Electrospray Ionization
1
2008
179
0.070
 Why?
Kidney
1
2015
1385
0.070
 Why?
Base Sequence
1
2011
2142
0.070
 Why?
Cells, Cultured
2
2013
4083
0.070
 Why?
Phosphatidylinositol Phosphates
1
2007
39
0.070
 Why?
Lung Neoplasms
2
2011
2344
0.070
 Why?
Static Electricity
1
2007
116
0.070
 Why?
Hydrolysis
1
2007
186
0.070
 Why?
Immunohistochemistry
1
2011
1698
0.070
 Why?
Cloning, Molecular
2
2020
524
0.060
 Why?
Amino Acid Substitution
1
2007
282
0.060
 Why?
Peptides
1
2011
925
0.060
 Why?
Phospholipids
1
2007
215
0.060
 Why?
Rats, Sprague-Dawley
1
2011
2406
0.060
 Why?
Metabolome
2
2019
338
0.060
 Why?
Skin
1
2010
725
0.060
 Why?
Kupffer Cells
1
2025
49
0.060
 Why?
Transcription Factors
1
2013
1651
0.060
 Why?
Biomarkers, Tumor
1
2011
1181
0.060
 Why?
Glycosylation
2
2016
150
0.050
 Why?
Amino Acids
2
2018
485
0.050
 Why?
Rats
1
2011
5500
0.050
 Why?
Sterols
1
2021
18
0.050
 Why?
Multidrug Resistance-Associated Proteins
1
2021
37
0.050
 Why?
Systems Analysis
1
2021
21
0.050
 Why?
Electrophoresis, Gel, Two-Dimensional
2
2012
110
0.050
 Why?
Intestinal Diseases
1
2021
36
0.050
 Why?
Fatty Acids
2
2016
427
0.050
 Why?
Receptors, Tumor Necrosis Factor, Type I
1
2021
85
0.050
 Why?
Bilirubin
1
2021
96
0.050
 Why?
Infliximab
1
2021
100
0.050
 Why?
Gas Chromatography-Mass Spectrometry
1
2021
131
0.050
 Why?
Chromatin Immunoprecipitation
1
2021
132
0.050
 Why?
Protein Conformation, beta-Strand
1
2020
15
0.040
 Why?
Apoptosis
1
2010
2503
0.040
 Why?
Sphingomyelins
1
2020
29
0.040
 Why?
Ursodeoxycholic Acid
1
2020
19
0.040
 Why?
Phosphatidylinositols
1
2020
57
0.040
 Why?
Calcium
1
2007
1213
0.040
 Why?
Phosphatidylethanolamines
1
2020
74
0.040
 Why?
Phosphatidylserines
1
2020
88
0.040
 Why?
Dextran Sulfate
1
2020
78
0.040
 Why?
Molecular Docking Simulation
1
2020
109
0.040
 Why?
Gene Knockdown Techniques
1
2021
315
0.040
 Why?
Protein Interaction Domains and Motifs
1
2020
139
0.040
 Why?
Lipid Bilayers
1
2020
98
0.040
 Why?
Interleukin-1beta
1
2021
372
0.040
 Why?
Genetic Vectors
1
2020
312
0.040
 Why?
Crystallography, X-Ray
1
2020
436
0.040
 Why?
Molecular Dynamics Simulation
1
2020
217
0.040
 Why?
Sirtuins
1
2019
39
0.040
 Why?
Disease Susceptibility
1
2020
333
0.040
 Why?
Aged
1
2017
22103
0.040
 Why?
gamma-Glutamyltransferase
1
2018
42
0.040
 Why?
Gene Expression Profiling
1
2025
1706
0.040
 Why?
Metabolic Networks and Pathways
1
2019
178
0.040
 Why?
Cystathionine beta-Synthase
1
2018
69
0.030
 Why?
F2-Isoprostanes
1
2016
20
0.030
 Why?
Protein D-Aspartate-L-Isoaspartate Methyltransferase
1
2016
5
0.030
 Why?
Escherichia coli
1
2020
774
0.030
 Why?
Sumoylation
1
2016
16
0.030
 Why?
Oxides
1
2016
41
0.030
 Why?
Insulin-Secreting Cells
1
2020
367
0.030
 Why?
Mutation
1
2007
3717
0.030
 Why?
Methylation
1
2016
230
0.030
 Why?
Chemokine CXCL2
1
2014
43
0.030
 Why?
Receptor, Platelet-Derived Growth Factor beta
1
2014
29
0.030
 Why?
Lipopolysaccharide Receptors
1
2014
87
0.030
 Why?
Oxidative Phosphorylation
1
2015
187
0.030
 Why?
Unfolded Protein Response
1
2014
53
0.030
 Why?
Matrix Metalloproteinases
1
2014
90
0.030
 Why?
Protein Folding
1
2014
266
0.030
 Why?
Antibodies
1
2014
398
0.030
 Why?
Anilino Naphthalenesulfonates
1
2012
10
0.020
 Why?
Cyclic AMP Response Element-Binding Protein
1
2013
141
0.020
 Why?
Actins
1
2014
411
0.020
 Why?
Transforming Growth Factor beta
1
2014
457
0.020
 Why?
Gene Expression Regulation, Enzymologic
1
2013
287
0.020
 Why?
Fibrosis
1
2014
520
0.020
 Why?
Ubiquitination
1
2012
98
0.020
 Why?
Immunoprecipitation
1
2012
157
0.020
 Why?
Lipid Metabolism
1
2015
497
0.020
 Why?
Protein Structure, Tertiary
1
2014
840
0.020
 Why?
Disease Progression
1
2019
2635
0.020
 Why?
Microsomes, Liver
1
2011
87
0.020
 Why?
NAD
1
2011
75
0.020
 Why?
Transcriptome
1
2016
887
0.020
 Why?
Sequence Alignment
1
2011
332
0.020
 Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2012
958
0.020
 Why?
Computer Simulation
1
2014
943
0.020
 Why?
Hypoxia
1
2016
1084
0.020
 Why?
Lipids
1
2013
625
0.020
 Why?
Mass Spectrometry
1
2012
716
0.020
 Why?
Mice, Transgenic
1
2013
2119
0.020
 Why?
Gene Expression Regulation, Neoplastic
1
2013
1356
0.020
 Why?
Cytokines
1
2014
2017
0.020
 Why?
Genetic Predisposition to Disease
1
2013
2282
0.010
 Why?
Adolescent
1
2016
20393
0.010
 Why?
Child
1
2016
20883
0.010
 Why?
Shearn's Networks
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