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Colin Shearn

Concepts (298)

Concepts are derived automatically from a person's publications.

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Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Cholestasis
10
2023
232
3.690
 Why?
Aldehydes
15
2022
145
3.360
 Why?
Liver
22
2025
1940
2.930
 Why?
Protein Carbonylation
10
2018
54
2.630
 Why?
PTEN Phosphohydrolase
7
2018
162
2.590
 Why?
Liver Diseases, Alcoholic
12
2019
93
2.550
 Why?
Bile Acids and Salts
7
2024
200
2.220
 Why?
Ethanol
12
2019
606
1.870
 Why?
Glutathione Transferase
8
2019
105
1.710
 Why?
Antioxidants
7
2023
584
1.700
 Why?
Cholangitis, Sclerosing
4
2024
75
1.650
 Why?
Parenteral Nutrition
5
2024
107
1.400
 Why?
Proto-Oncogene Proteins c-akt
6
2016
437
1.390
 Why?
Oxidative Stress
14
2019
1314
1.240
 Why?
Ileum
2
2024
119
1.070
 Why?
Fatty Liver
3
2014
243
1.060
 Why?
Mice, Inbred C57BL
17
2025
5749
0.980
 Why?
Tumor Necrosis Factor-alpha
5
2024
1242
0.950
 Why?
Inflammatory Bowel Diseases
3
2020
351
0.950
 Why?
Fatty Liver, Alcoholic
2
2016
15
0.930
 Why?
Mice
37
2025
17757
0.920
 Why?
Signal Transduction
11
2024
5076
0.890
 Why?
Thioredoxins
3
2018
30
0.860
 Why?
Carcinoma, Hepatocellular
3
2019
361
0.770
 Why?
Abdominal Injuries
1
2023
123
0.760
 Why?
AMP-Activated Protein Kinases
2
2014
197
0.750
 Why?
Protein Processing, Post-Translational
4
2016
465
0.700
 Why?
Animals
39
2025
36847
0.690
 Why?
Circadian Rhythm
1
2024
469
0.670
 Why?
Butylated Hydroxytoluene
2
2011
38
0.650
 Why?
Disease Models, Animal
13
2025
4282
0.620
 Why?
Hepatocytes
5
2021
220
0.620
 Why?
Peroxiredoxins
2
2018
24
0.620
 Why?
Thioredoxin-Disulfide Reductase
1
2018
13
0.590
 Why?
NF-E2-Related Factor 2
2
2019
93
0.590
 Why?
Non-alcoholic Fatty Liver Disease
3
2017
279
0.560
 Why?
Gene Knockout Techniques
1
2018
117
0.560
 Why?
Hepatitis
1
2017
48
0.550
 Why?
Liver Diseases
2
2021
311
0.540
 Why?
Liver Cirrhosis
3
2024
316
0.520
 Why?
Receptors, Cytoplasmic and Nuclear
3
2024
219
0.520
 Why?
Liver Neoplasms
4
2019
785
0.520
 Why?
Superoxide Dismutase
5
2019
346
0.510
 Why?
Mitochondrial Proteins
2
2015
256
0.510
 Why?
Chemical and Drug Induced Liver Injury, Chronic
1
2016
12
0.510
 Why?
End Stage Liver Disease
1
2017
82
0.500
 Why?
Thioredoxin Reductase 1
3
2023
8
0.500
 Why?
Liver Cirrhosis, Alcoholic
1
2015
17
0.490
 Why?
Tandem Mass Spectrometry
5
2022
532
0.470
 Why?
Alcoholism
3
2018
804
0.450
 Why?
ARNTL Transcription Factors
2
2024
17
0.440
 Why?
Oxidants
2
2012
111
0.430
 Why?
Diet, High-Fat
2
2016
247
0.420
 Why?
Mice, Knockout
8
2020
3008
0.410
 Why?
Male
30
2025
67311
0.410
 Why?
Dietary Fats
2
2018
304
0.380
 Why?
Lipid Peroxidation
4
2016
153
0.370
 Why?
RNA, Messenger
6
2023
2831
0.360
 Why?
Xenobiotics
1
2011
32
0.350
 Why?
Hydrogen Peroxide
1
2012
327
0.340
 Why?
Chromatography, Liquid
4
2017
433
0.330
 Why?
Oxidoreductases Acting on CH-CH Group Donors
1
2010
26
0.330
 Why?
Cell Proliferation
3
2018
2475
0.330
 Why?
Glutathione Reductase
3
2019
25
0.330
 Why?
Alcohol Drinking
1
2016
820
0.310
 Why?
Inflammation
5
2023
2835
0.310
 Why?
Mitochondria
4
2019
946
0.300
 Why?
Down-Regulation
1
2011
656
0.300
 Why?
Blotting, Western
4
2016
1225
0.290
 Why?
Carcinoma
1
2010
238
0.290
 Why?
Autophagy
2
2022
280
0.280
 Why?
Alcohol Oxidoreductases
1
2008
62
0.280
 Why?
Colonic Neoplasms
1
2010
254
0.280
 Why?
Carcinogens
1
2008
124
0.280
 Why?
Catalase
2
2017
130
0.280
 Why?
Phosphoric Monoester Hydrolases
1
2007
54
0.260
 Why?
NF-kappa B
2
2021
691
0.260
 Why?
Glutathione
4
2019
356
0.250
 Why?
Hep G2 Cells
3
2021
67
0.240
 Why?
Alanine Transaminase
3
2016
157
0.240
 Why?
Up-Regulation
2
2019
844
0.240
 Why?
Case-Control Studies
3
2018
3539
0.230
 Why?
Recombinant Proteins
4
2020
1350
0.230
 Why?
Protein Kinase Inhibitors
1
2011
916
0.230
 Why?
Gene Expression Regulation
5
2021
2605
0.230
 Why?
Enzyme Inhibitors
1
2008
839
0.230
 Why?
Humans
27
2023
136765
0.220
 Why?
Macrophage Activation
2
2023
201
0.220
 Why?
Ileitis
1
2024
32
0.220
 Why?
Biomarkers
1
2015
4144
0.220
 Why?
Proteomics
4
2019
1109
0.210
 Why?
Phosphorylation
3
2014
1758
0.210
 Why?
Epithelial Cells
1
2010
1094
0.210
 Why?
Genes, Regulator
1
2023
37
0.210
 Why?
Lipoproteins
2
2021
168
0.210
 Why?
Fibroblast Growth Factors
1
2024
171
0.210
 Why?
Cysteine Proteinase Inhibitors
2
2014
49
0.200
 Why?
Biliary Atresia
1
2025
163
0.200
 Why?
Sulfhydryl Compounds
2
2018
189
0.200
 Why?
Insulin Resistance
1
2011
1203
0.190
 Why?
Prostatic Neoplasms
1
2010
1034
0.190
 Why?
Fatty Acid-Binding Proteins
2
2013
70
0.190
 Why?
Enzyme Activation
3
2013
810
0.190
 Why?
Triglycerides
2
2016
524
0.190
 Why?
Mitochondria, Liver
2
2013
73
0.190
 Why?
Dioxanes
1
2021
10
0.190
 Why?
NLR Family, Pyrin Domain-Containing 3 Protein
1
2023
151
0.180
 Why?
Isoxazoles
1
2021
54
0.180
 Why?
Phytosterols
1
2021
12
0.180
 Why?
Oxidation-Reduction
3
2019
1059
0.180
 Why?
Mucoproteins
1
2020
10
0.170
 Why?
Models, Molecular
4
2014
1570
0.170
 Why?
Phosphatidylinositol 4,5-Diphosphate
1
2020
32
0.170
 Why?
Cholesterol
2
2020
410
0.170
 Why?
Vesicular Transport Proteins
1
2020
84
0.160
 Why?
Phosphatidylcholines
1
2020
147
0.160
 Why?
Gene Expression
2
2021
1500
0.160
 Why?
Macrophages
2
2025
1544
0.160
 Why?
Cell Adhesion Molecules
1
2020
181
0.160
 Why?
Acylation
1
2019
30
0.150
 Why?
Liposomes
1
2020
220
0.150
 Why?
Lysosomes
1
2019
141
0.150
 Why?
Chromatography, High Pressure Liquid
2
2013
597
0.150
 Why?
PPAR alpha
2
2016
58
0.150
 Why?
Female
10
2025
72795
0.140
 Why?
Mice, 129 Strain
1
2018
88
0.140
 Why?
Heme Oxygenase-1
1
2018
64
0.140
 Why?
Sulfinic Acids
1
2018
7
0.140
 Why?
Colon
1
2020
282
0.140
 Why?
Ribosomes
1
2019
186
0.140
 Why?
Lung
1
2011
4062
0.140
 Why?
Aminobutyrates
1
2018
35
0.140
 Why?
Azo Compounds
1
2017
30
0.140
 Why?
Reactive Oxygen Species
2
2011
621
0.140
 Why?
Colitis
1
2020
266
0.140
 Why?
Taurine
1
2018
46
0.140
 Why?
Organ Specificity
1
2018
304
0.140
 Why?
Pyruvaldehyde
1
2018
46
0.140
 Why?
HSP70 Heat-Shock Proteins
1
2017
73
0.140
 Why?
Protein Structure, Secondary
1
2018
374
0.130
 Why?
Gene Deletion
2
2015
389
0.130
 Why?
Homocystinuria
1
2018
71
0.130
 Why?
Malnutrition
1
2018
82
0.130
 Why?
Mice, Inbred BALB C
2
2011
1269
0.130
 Why?
Amino Acid Sequence
4
2015
2138
0.130
 Why?
Cell Line, Tumor
3
2020
3405
0.120
 Why?
Lipogenesis
1
2016
61
0.120
 Why?
Middle Aged
4
2019
33228
0.120
 Why?
Fatty Acids, Unsaturated
1
2016
98
0.120
 Why?
Sirtuin 3
2
2019
61
0.120
 Why?
Lysine
1
2017
294
0.120
 Why?
Adult
4
2019
37631
0.110
 Why?
Cytochrome P-450 CYP4A
1
2014
4
0.110
 Why?
Acetylation
4
2017
248
0.110
 Why?
CD36 Antigens
1
2014
36
0.110
 Why?
Proteome
1
2019
472
0.110
 Why?
Protein Isoforms
1
2015
403
0.110
 Why?
Central Nervous System Depressants
1
2014
85
0.100
 Why?
Endoplasmic Reticulum Stress
1
2014
109
0.100
 Why?
Heat-Shock Proteins
1
2014
142
0.100
 Why?
Phosphatidylinositol 3-Kinases
2
2013
366
0.100
 Why?
DNA Primers
2
2012
514
0.100
 Why?
Protein Binding
4
2020
2216
0.100
 Why?
Adenosine Triphosphatases
1
2014
165
0.100
 Why?
Acetyl-CoA Carboxylase
1
2013
33
0.100
 Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
1
2013
24
0.100
 Why?
Carrier Proteins
1
2017
769
0.100
 Why?
Sterol Regulatory Element Binding Protein 1
1
2013
57
0.100
 Why?
Molecular Sequence Data
3
2015
2894
0.100
 Why?
Computational Biology
1
2017
643
0.100
 Why?
Models, Chemical
1
2014
263
0.100
 Why?
Endoplasmic Reticulum
2
2014
264
0.100
 Why?
Polymerase Chain Reaction
2
2016
1059
0.100
 Why?
Organ Size
1
2013
477
0.090
 Why?
Reactive Nitrogen Species
1
2011
21
0.090
 Why?
Peptide Mapping
1
2011
64
0.090
 Why?
Glycogen Synthase Kinase 3 beta
1
2011
72
0.090
 Why?
Adiponectin
1
2013
244
0.090
 Why?
Glycogen Synthase Kinase 3
1
2011
82
0.090
 Why?
Binding Sites
2
2020
1301
0.090
 Why?
Crotonates
1
2010
5
0.080
 Why?
Toluidines
1
2010
7
0.080
 Why?
Hydroxybutyrates
1
2010
14
0.080
 Why?
Fenretinide
1
2010
4
0.080
 Why?
Receptors, Estrogen
1
2013
436
0.080
 Why?
Tumor Cells, Cultured
1
2012
953
0.080
 Why?
Oxygen Consumption
1
2013
695
0.080
 Why?
Cell Line, Transformed
1
2010
145
0.080
 Why?
Microscopy, Confocal
1
2011
324
0.080
 Why?
Fluorescence Resonance Energy Transfer
1
2011
177
0.080
 Why?
Nitriles
1
2010
172
0.080
 Why?
Protein Conformation
1
2012
933
0.080
 Why?
Glycoproteins
1
2011
342
0.080
 Why?
Cell Survival
1
2012
1116
0.070
 Why?
Alkylation
1
2008
26
0.070
 Why?
Nuclear Proteins
1
2013
712
0.070
 Why?
Spectrometry, Mass, Electrospray Ionization
1
2008
180
0.070
 Why?
Cytosol
1
2008
226
0.070
 Why?
RNA, Small Interfering
1
2010
622
0.070
 Why?
DNA Damage
2
2021
420
0.070
 Why?
Kidney
1
2015
1467
0.070
 Why?
Base Sequence
1
2011
2179
0.070
 Why?
Phosphatidylinositol Phosphates
1
2007
39
0.070
 Why?
Cells, Cultured
2
2013
4191
0.070
 Why?
Static Electricity
1
2007
118
0.070
 Why?
Hydrolysis
1
2007
176
0.070
 Why?
Immunohistochemistry
1
2011
1733
0.060
 Why?
Lung Neoplasms
2
2011
2489
0.060
 Why?
Cloning, Molecular
2
2020
534
0.060
 Why?
Amino Acid Substitution
1
2007
306
0.060
 Why?
Phospholipids
1
2007
222
0.060
 Why?
Rats, Sprague-Dawley
1
2011
2486
0.060
 Why?
Skin
1
2010
751
0.060
 Why?
Peptides
1
2011
980
0.060
 Why?
Metabolome
2
2019
350
0.060
 Why?
Kupffer Cells
1
2025
50
0.060
 Why?
Transcription Factors
1
2013
1718
0.060
 Why?
Biomarkers, Tumor
1
2011
1272
0.050
 Why?
Glycosylation
2
2016
151
0.050
 Why?
Amino Acids
2
2018
497
0.050
 Why?
Rats
1
2011
5639
0.050
 Why?
Sterols
1
2021
18
0.050
 Why?
Multidrug Resistance-Associated Proteins
1
2021
38
0.050
 Why?
Systems Analysis
1
2021
23
0.050
 Why?
Electrophoresis, Gel, Two-Dimensional
2
2012
114
0.050
 Why?
Receptors, Tumor Necrosis Factor, Type I
1
2021
87
0.050
 Why?
Intestinal Diseases
1
2021
42
0.050
 Why?
Fatty Acids
2
2016
442
0.050
 Why?
Bilirubin
1
2021
97
0.050
 Why?
Gas Chromatography-Mass Spectrometry
1
2021
132
0.040
 Why?
Infliximab
1
2021
111
0.040
 Why?
Chromatin Immunoprecipitation
1
2021
138
0.040
 Why?
Protein Conformation, beta-Strand
1
2020
17
0.040
 Why?
Sphingomyelins
1
2020
33
0.040
 Why?
Apoptosis
1
2010
2551
0.040
 Why?
Ursodeoxycholic Acid
1
2020
21
0.040
 Why?
Calcium
1
2007
1197
0.040
 Why?
Phosphatidylinositols
1
2020
57
0.040
 Why?
Phosphatidylethanolamines
1
2020
77
0.040
 Why?
Phosphatidylserines
1
2020
91
0.040
 Why?
Dextran Sulfate
1
2020
83
0.040
 Why?
Molecular Docking Simulation
1
2020
113
0.040
 Why?
Gene Knockdown Techniques
1
2021
327
0.040
 Why?
Protein Interaction Domains and Motifs
1
2020
150
0.040
 Why?
Lipid Bilayers
1
2020
97
0.040
 Why?
Interleukin-1beta
1
2021
371
0.040
 Why?
Genetic Vectors
1
2020
317
0.040
 Why?
Crystallography, X-Ray
1
2020
476
0.040
 Why?
Molecular Dynamics Simulation
1
2020
211
0.040
 Why?
Sirtuins
1
2019
40
0.040
 Why?
Disease Susceptibility
1
2020
345
0.040
 Why?
gamma-Glutamyltransferase
1
2018
43
0.040
 Why?
Aged
1
2017
23794
0.040
 Why?
Metabolic Networks and Pathways
1
2019
180
0.040
 Why?
Gene Expression Profiling
1
2025
1772
0.030
 Why?
Cystathionine beta-Synthase
1
2018
71
0.030
 Why?
F2-Isoprostanes
1
2016
21
0.030
 Why?
Protein D-Aspartate-L-Isoaspartate Methyltransferase
1
2016
5
0.030
 Why?
Sumoylation
1
2016
16
0.030
 Why?
Escherichia coli
1
2020
806
0.030
 Why?
Oxides
1
2016
46
0.030
 Why?
Insulin-Secreting Cells
1
2020
372
0.030
 Why?
Methylation
1
2016
230
0.030
 Why?
Mutation
1
2007
3946
0.030
 Why?
Chemokine CXCL2
1
2014
43
0.030
 Why?
Receptor, Platelet-Derived Growth Factor beta
1
2014
29
0.030
 Why?
Lipopolysaccharide Receptors
1
2014
85
0.030
 Why?
Oxidative Phosphorylation
1
2015
193
0.030
 Why?
Unfolded Protein Response
1
2014
59
0.030
 Why?
Matrix Metalloproteinases
1
2014
95
0.030
 Why?
Protein Folding
1
2014
280
0.020
 Why?
Antibodies
1
2014
411
0.020
 Why?
Anilino Naphthalenesulfonates
1
2012
10
0.020
 Why?
Cyclic AMP Response Element-Binding Protein
1
2013
145
0.020
 Why?
Actins
1
2014
416
0.020
 Why?
Gene Expression Regulation, Enzymologic
1
2013
283
0.020
 Why?
Ubiquitination
1
2012
102
0.020
 Why?
Immunoprecipitation
1
2012
155
0.020
 Why?
Fibrosis
1
2014
551
0.020
 Why?
Transforming Growth Factor beta
1
2014
480
0.020
 Why?
Lipid Metabolism
1
2015
512
0.020
 Why?
Protein Structure, Tertiary
1
2014
860
0.020
 Why?
Disease Progression
1
2019
2750
0.020
 Why?
Microsomes, Liver
1
2011
86
0.020
 Why?
NAD
1
2011
77
0.020
 Why?
Sequence Alignment
1
2011
342
0.020
 Why?
Transcriptome
1
2016
969
0.020
 Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2012
975
0.020
 Why?
Computer Simulation
1
2014
973
0.020
 Why?
Hypoxia
1
2016
1112
0.020
 Why?
Mass Spectrometry
1
2012
738
0.020
 Why?
Lipids
1
2013
665
0.020
 Why?
Mice, Transgenic
1
2013
2163
0.020
 Why?
Gene Expression Regulation, Neoplastic
1
2013
1396
0.020
 Why?
Cytokines
1
2014
2084
0.020
 Why?
Genetic Predisposition to Disease
1
2013
2412
0.010
 Why?
Adolescent
1
2016
21382
0.010
 Why?
Child
1
2016
21819
0.010
 Why?
Shearn's Networks
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