Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Colin Shearn

Concepts (302)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Protein Carbonylation
12
2025
57
3.610
Why?
Cholestasis
10
2023
219
3.500
Why?
Aldehydes
16
2025
142
3.420
Why?
Liver
22
2025
1888
2.780
Why?
PTEN Phosphohydrolase
7
2018
165
2.460
Why?
Liver Diseases, Alcoholic
12
2019
97
2.400
Why?
Bile Acids and Salts
7
2024
164
2.150
Why?
Oxidative Stress
16
2025
1339
1.880
Why?
Ethanol
12
2019
627
1.760
Why?
Antioxidants
7
2023
549
1.630
Why?
Glutathione Transferase
8
2019
100
1.630
Why?
Cholangitis, Sclerosing
4
2024
60
1.590
Why?
Parenteral Nutrition
5
2024
105
1.340
Why?
Proto-Oncogene Proteins c-akt
6
2016
437
1.330
Why?
Ileum
2
2024
111
1.010
Why?
Fatty Liver
3
2014
251
1.000
Why?
Mice
38
2025
18365
0.930
Why?
Tumor Necrosis Factor-alpha
5
2024
1217
0.920
Why?
Mice, Inbred C57BL
17
2025
5997
0.910
Why?
Inflammatory Bowel Diseases
3
2020
365
0.900
Why?
Fatty Liver, Alcoholic
2
2016
14
0.880
Why?
Insulin-Secreting Cells
3
2025
388
0.860
Why?
Signal Transduction
11
2024
5233
0.840
Why?
Thioredoxins
3
2018
31
0.820
Why?
Carcinoma, Hepatocellular
3
2019
372
0.720
Why?
Abdominal Injuries
1
2023
127
0.720
Why?
AMP-Activated Protein Kinases
2
2014
191
0.720
Why?
Animals
41
2025
38109
0.710
Why?
Protein Processing, Post-Translational
4
2016
477
0.660
Why?
Butylated Hydroxytoluene
2
2011
36
0.620
Why?
Circadian Rhythm
1
2024
514
0.620
Why?
Hepatocytes
5
2021
224
0.590
Why?
Peroxiredoxins
2
2018
26
0.580
Why?
Disease Models, Animal
13
2025
4569
0.580
Why?
Thioredoxin-Disulfide Reductase
1
2018
14
0.560
Why?
NF-E2-Related Factor 2
2
2019
95
0.560
Why?
Non-alcoholic Fatty Liver Disease
3
2017
266
0.550
Why?
Gene Knockout Techniques
1
2018
116
0.540
Why?
Hepatitis
1
2017
43
0.520
Why?
Liver Diseases
2
2021
304
0.510
Why?
Liver Cirrhosis
3
2024
288
0.500
Why?
Superoxide Dismutase
5
2019
301
0.500
Why?
Receptors, Cytoplasmic and Nuclear
3
2024
210
0.500
Why?
Mitochondrial Proteins
2
2015
263
0.490
Why?
Chemical and Drug Induced Liver Injury, Chronic
1
2016
11
0.480
Why?
Liver Neoplasms
4
2019
783
0.480
Why?
End Stage Liver Disease
1
2017
94
0.480
Why?
Thioredoxin Reductase 1
3
2023
8
0.480
Why?
Liver Cirrhosis, Alcoholic
1
2015
19
0.470
Why?
Tandem Mass Spectrometry
5
2022
577
0.440
Why?
Insulin
1
2025
2507
0.420
Why?
Alcoholism
3
2018
817
0.420
Why?
Oxidants
2
2012
103
0.420
Why?
ARNTL Transcription Factors
2
2024
17
0.420
Why?
Diet, High-Fat
2
2016
261
0.400
Why?
Inflammation
6
2025
2880
0.390
Why?
Mice, Knockout
8
2020
3125
0.390
Why?
Male
30
2025
72406
0.370
Why?
Dietary Fats
2
2018
315
0.360
Why?
Lipid Peroxidation
4
2016
160
0.350
Why?
Proteomics
5
2025
1195
0.340
Why?
RNA, Messenger
6
2023
2832
0.340
Why?
Xenobiotics
1
2011
32
0.340
Why?
Hydrogen Peroxide
1
2012
336
0.320
Why?
Reactive Oxygen Species
3
2025
621
0.320
Why?
Chromatography, Liquid
4
2017
454
0.320
Why?
Oxidoreductases Acting on CH-CH Group Donors
1
2010
27
0.310
Why?
Cell Proliferation
3
2018
2499
0.310
Why?
Glutathione Reductase
3
2019
25
0.310
Why?
Alcohol Drinking
1
2016
826
0.290
Why?
Mitochondria
4
2019
984
0.280
Why?
Down-Regulation
1
2011
627
0.280
Why?
Blotting, Western
4
2016
1187
0.280
Why?
Carcinoma
1
2010
228
0.280
Why?
Autophagy
2
2022
286
0.270
Why?
Alcohol Oxidoreductases
1
2008
62
0.270
Why?
Carcinogens
1
2008
123
0.270
Why?
Colonic Neoplasms
1
2010
260
0.260
Why?
Catalase
2
2017
130
0.260
Why?
Phosphoric Monoester Hydrolases
1
2007
56
0.250
Why?
NF-kappa B
2
2021
662
0.250
Why?
Glutathione
4
2019
375
0.230
Why?
Alanine Transaminase
3
2016
151
0.230
Why?
Hep G2 Cells
3
2021
75
0.230
Why?
Up-Regulation
2
2019
852
0.230
Why?
Case-Control Studies
3
2018
3608
0.220
Why?
Gene Expression Regulation
5
2021
2609
0.220
Why?
Recombinant Proteins
4
2020
1371
0.220
Why?
Enzyme Inhibitors
1
2008
826
0.220
Why?
Humans
28
2025
144957
0.210
Why?
Protein Kinase Inhibitors
1
2011
970
0.210
Why?
Macrophage Activation
2
2023
193
0.210
Why?
Ileitis
1
2024
33
0.210
Why?
Biomarkers
1
2015
4275
0.210
Why?
Phosphorylation
3
2014
1733
0.200
Why?
Mice, Inbred NOD
1
2025
610
0.200
Why?
Genes, Regulator
1
2023
35
0.200
Why?
Epithelial Cells
1
2010
1126
0.200
Why?
Lipoproteins
2
2021
169
0.200
Why?
Cysteine Proteinase Inhibitors
2
2014
50
0.190
Why?
Fibroblast Growth Factors
1
2024
188
0.190
Why?
Biliary Atresia
1
2025
158
0.190
Why?
Sulfhydryl Compounds
2
2018
189
0.190
Why?
Prostatic Neoplasms
1
2010
978
0.190
Why?
Insulin Resistance
1
2011
1241
0.180
Why?
Enzyme Activation
3
2013
768
0.180
Why?
Triglycerides
2
2016
521
0.180
Why?
Fatty Acid-Binding Proteins
2
2013
79
0.180
Why?
Mitochondria, Liver
2
2013
70
0.180
Why?
Dioxanes
1
2021
10
0.180
Why?
Isoxazoles
1
2021
54
0.170
Why?
Phytosterols
1
2021
12
0.170
Why?
NLR Family, Pyrin Domain-Containing 3 Protein
1
2023
169
0.170
Why?
Oxidation-Reduction
3
2019
1087
0.170
Why?
Mucoproteins
1
2020
8
0.160
Why?
Female
11
2025
78376
0.160
Why?
Phosphatidylinositol 4,5-Diphosphate
1
2020
32
0.160
Why?
Models, Molecular
4
2014
1619
0.160
Why?
Cholesterol
2
2020
408
0.160
Why?
Vesicular Transport Proteins
1
2020
86
0.160
Why?
Phosphatidylcholines
1
2020
131
0.160
Why?
Gene Expression
2
2021
1490
0.150
Why?
Macrophages
2
2025
1511
0.150
Why?
Cell Adhesion Molecules
1
2020
178
0.150
Why?
Cytokines
2
2025
2065
0.150
Why?
Acylation
1
2019
30
0.150
Why?
Lysosomes
1
2019
128
0.140
Why?
Chromatography, High Pressure Liquid
2
2013
598
0.140
Why?
Liposomes
1
2020
250
0.140
Why?
PPAR alpha
2
2016
54
0.140
Why?
Mice, 129 Strain
1
2018
86
0.140
Why?
Sulfinic Acids
1
2018
6
0.140
Why?
Ribosomes
1
2019
191
0.140
Why?
Heme Oxygenase-1
1
2018
74
0.130
Why?
Colon
1
2020
305
0.130
Why?
Aminobutyrates
1
2018
31
0.130
Why?
Lung
1
2011
4109
0.130
Why?
Azo Compounds
1
2017
30
0.130
Why?
Taurine
1
2018
41
0.130
Why?
Organ Specificity
1
2018
313
0.130
Why?
Colitis
1
2020
280
0.130
Why?
Pyruvaldehyde
1
2018
50
0.130
Why?
HSP70 Heat-Shock Proteins
1
2017
76
0.130
Why?
Protein Structure, Secondary
1
2018
369
0.130
Why?
Gene Deletion
2
2015
389
0.130
Why?
Homocystinuria
1
2018
62
0.130
Why?
Mice, Inbred BALB C
2
2011
1253
0.130
Why?
Malnutrition
1
2018
86
0.130
Why?
Diabetes Mellitus
1
2025
1098
0.120
Why?
Amino Acid Sequence
4
2015
2157
0.120
Why?
Lipogenesis
1
2016
62
0.120
Why?
Cell Line, Tumor
3
2020
3550
0.120
Why?
Fatty Acids, Unsaturated
1
2016
98
0.120
Why?
Sirtuin 3
2
2019
60
0.110
Why?
Middle Aged
4
2019
35928
0.110
Why?
Lysine
1
2017
302
0.110
Why?
Cytochrome P-450 CYP4A
1
2014
4
0.110
Why?
Acetylation
4
2017
256
0.110
Why?
CD36 Antigens
1
2014
32
0.110
Why?
Protein Isoforms
1
2015
402
0.100
Why?
Adult
4
2019
40506
0.100
Why?
Proteome
1
2019
518
0.100
Why?
Central Nervous System Depressants
1
2014
83
0.100
Why?
Heat-Shock Proteins
1
2014
138
0.100
Why?
DNA Primers
2
2012
512
0.100
Why?
Carrier Proteins
1
2017
737
0.100
Why?
Phosphatidylinositol 3-Kinases
2
2013
381
0.100
Why?
Endoplasmic Reticulum Stress
1
2014
120
0.100
Why?
Adenosine Triphosphatases
1
2014
162
0.100
Why?
Protein Binding
4
2020
2276
0.100
Why?
Acetyl-CoA Carboxylase
1
2013
32
0.100
Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
1
2013
26
0.100
Why?
Molecular Sequence Data
3
2015
2931
0.100
Why?
Sterol Regulatory Element Binding Protein 1
1
2013
55
0.100
Why?
Computational Biology
1
2017
681
0.090
Why?
Models, Chemical
1
2014
269
0.090
Why?
Endoplasmic Reticulum
2
2014
266
0.090
Why?
Polymerase Chain Reaction
2
2016
1054
0.090
Why?
Organ Size
1
2013
463
0.090
Why?
Reactive Nitrogen Species
1
2011
16
0.090
Why?
Peptide Mapping
1
2011
63
0.080
Why?
Adiponectin
1
2013
244
0.080
Why?
Glycogen Synthase Kinase 3 beta
1
2011
72
0.080
Why?
Diabetes Mellitus, Type 2
1
2025
2584
0.080
Why?
Glycogen Synthase Kinase 3
1
2011
81
0.080
Why?
Binding Sites
2
2020
1331
0.080
Why?
Fenretinide
1
2010
3
0.080
Why?
Crotonates
1
2010
7
0.080
Why?
Toluidines
1
2010
10
0.080
Why?
Hydroxybutyrates
1
2010
15
0.080
Why?
Tumor Cells, Cultured
1
2012
919
0.080
Why?
Receptors, Estrogen
1
2013
457
0.080
Why?
Oxygen Consumption
1
2013
724
0.080
Why?
Cell Line, Transformed
1
2010
140
0.080
Why?
Microscopy, Confocal
1
2011
321
0.080
Why?
Fluorescence Resonance Energy Transfer
1
2011
178
0.080
Why?
Protein Conformation
1
2012
946
0.070
Why?
Glycoproteins
1
2011
355
0.070
Why?
Nitriles
1
2010
205
0.070
Why?
Cell Survival
1
2012
1098
0.070
Why?
Alkylation
1
2008
27
0.070
Why?
Diabetes Mellitus, Type 1
1
2025
3890
0.070
Why?
Nuclear Proteins
1
2013
749
0.070
Why?
Spectrometry, Mass, Electrospray Ionization
1
2008
179
0.070
Why?
RNA, Small Interfering
1
2010
635
0.070
Why?
Cytosol
1
2008
227
0.070
Why?
DNA Damage
2
2021
430
0.070
Why?
Base Sequence
1
2011
2191
0.060
Why?
Kidney
1
2015
1496
0.060
Why?
Cells, Cultured
2
2013
4155
0.060
Why?
Phosphatidylinositol Phosphates
1
2007
41
0.060
Why?
Static Electricity
1
2007
113
0.060
Why?
Immunohistochemistry
1
2011
1718
0.060
Why?
Hydrolysis
1
2007
199
0.060
Why?
Lung Neoplasms
2
2011
2642
0.060
Why?
Cloning, Molecular
2
2020
541
0.060
Why?
Amino Acid Substitution
1
2007
304
0.060
Why?
Phospholipids
1
2007
213
0.060
Why?
Rats, Sprague-Dawley
1
2011
2540
0.060
Why?
Peptides
1
2011
998
0.060
Why?
Skin
1
2010
758
0.060
Why?
Metabolome
2
2019
384
0.050
Why?
Kupffer Cells
1
2025
53
0.050
Why?
Transcription Factors
1
2013
1742
0.050
Why?
Biomarkers, Tumor
1
2011
1322
0.050
Why?
Glycosylation
2
2016
172
0.050
Why?
Amino Acids
2
2018
522
0.050
Why?
Rats
1
2011
5614
0.050
Why?
Sterols
1
2021
21
0.040
Why?
Systems Analysis
1
2021
22
0.040
Why?
Receptors, Tumor Necrosis Factor, Type I
1
2021
81
0.040
Why?
Electrophoresis, Gel, Two-Dimensional
2
2012
110
0.040
Why?
Intestinal Diseases
1
2021
43
0.040
Why?
Fatty Acids
2
2016
452
0.040
Why?
Bilirubin
1
2021
97
0.040
Why?
Apoptosis
1
2010
2430
0.040
Why?
Gas Chromatography-Mass Spectrometry
1
2021
131
0.040
Why?
Infliximab
1
2021
108
0.040
Why?
Chromatin Immunoprecipitation
1
2021
139
0.040
Why?
Protein Conformation, beta-Strand
1
2020
19
0.040
Why?
Sphingomyelins
1
2020
22
0.040
Why?
Calcium
1
2007
1184
0.040
Why?
Ursodeoxycholic Acid
1
2020
17
0.040
Why?
Phosphatidylinositols
1
2020
57
0.040
Why?
Phosphatidylserines
1
2020
60
0.040
Why?
Phosphatidylethanolamines
1
2020
76
0.040
Why?
Gene Knockdown Techniques
1
2021
336
0.040
Why?
Dextran Sulfate
1
2020
94
0.040
Why?
Molecular Docking Simulation
1
2020
124
0.040
Why?
Protein Interaction Domains and Motifs
1
2020
148
0.040
Why?
Lipid Bilayers
1
2020
103
0.040
Why?
Interleukin-1beta
1
2021
395
0.040
Why?
Genetic Vectors
1
2020
337
0.040
Why?
Crystallography, X-Ray
1
2020
493
0.040
Why?
Disease Susceptibility
1
2020
348
0.040
Why?
Molecular Dynamics Simulation
1
2020
260
0.040
Why?
Sirtuins
1
2019
50
0.040
Why?
gamma-Glutamyltransferase
1
2018
42
0.030
Why?
Metabolic Networks and Pathways
1
2019
187
0.030
Why?
Gene Expression Profiling
1
2025
1786
0.030
Why?
Cystathionine beta-Synthase
1
2018
65
0.030
Why?
Aged
1
2017
25947
0.030
Why?
F2-Isoprostanes
1
2016
20
0.030
Why?
Protein D-Aspartate-L-Isoaspartate Methyltransferase
1
2016
5
0.030
Why?
Sumoylation
1
2016
18
0.030
Why?
Oxides
1
2016
51
0.030
Why?
Escherichia coli
1
2020
855
0.030
Why?
Methylation
1
2016
242
0.030
Why?
Mutation
1
2007
4099
0.030
Why?
Chemokine CXCL2
1
2014
41
0.030
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2014
31
0.030
Why?
Lipopolysaccharide Receptors
1
2014
87
0.030
Why?
Matrix Metalloproteinases
1
2014
98
0.030
Why?
Oxidative Phosphorylation
1
2015
210
0.030
Why?
Unfolded Protein Response
1
2014
60
0.030
Why?
Protein Folding
1
2014
279
0.020
Why?
Anilino Naphthalenesulfonates
1
2012
10
0.020
Why?
Cyclic AMP Response Element-Binding Protein
1
2013
145
0.020
Why?
Antibodies
1
2014
403
0.020
Why?
Actins
1
2014
425
0.020
Why?
Gene Expression Regulation, Enzymologic
1
2013
269
0.020
Why?
Fibrosis
1
2014
548
0.020
Why?
Immunoprecipitation
1
2012
151
0.020
Why?
Transforming Growth Factor beta
1
2014
479
0.020
Why?
Ubiquitination
1
2012
118
0.020
Why?
Protein Structure, Tertiary
1
2014
862
0.020
Why?
Lipid Metabolism
1
2015
528
0.020
Why?
Disease Progression
1
2019
2852
0.020
Why?
Microsomes, Liver
1
2011
85
0.020
Why?
NAD
1
2011
81
0.020
Why?
Sequence Alignment
1
2011
368
0.020
Why?
Reverse Transcriptase Polymerase Chain Reaction
1
2012
983
0.020
Why?
Transcriptome
1
2016
1046
0.020
Why?
Computer Simulation
1
2014
1026
0.020
Why?
Mass Spectrometry
1
2012
750
0.020
Why?
Hypoxia
1
2016
1199
0.020
Why?
Lipids
1
2013
710
0.020
Why?
Mice, Transgenic
1
2013
2185
0.020
Why?
Gene Expression Regulation, Neoplastic
1
2013
1462
0.020
Why?
Genetic Predisposition to Disease
1
2013
2365
0.010
Why?
Adolescent
1
2016
22453
0.010
Why?
Child
1
2016
22657
0.010
Why?
Shearn's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts Expand Description
_
Co-Authors Expand Description
_
Similar People Expand Description
_
Same Department Expand Description
Physical Neighbors Expand Description
_

Copyright © 2026 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)