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Lucas Emerson Orth

TitleClinical Asst Professor
InstitutionUniversity of Colorado Denver - Anschutz Medical Campus
DepartmentSOP-Administration

    Collapse Biography 
    Collapse education and training
    University of Kentucky, Lexington, KentuckyDoctorate2015Pharmacy

    Collapse Overview 
    Collapse overview
    Lucas Orth, PharmD, BCPPS is an Assistant Professor in the Department of Clinical Pharmacy at the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences. In addition to his pediatric teaching roles within the pharmacy curriculum, Dr. Orth practices as an embedded pharmacist within the Special Care Clinic at Children's Hospital Colorado, a patient-centered medical home for ~6,000 children with medical complexity. Within this role, Dr. Orth works collaboratively with providers and multidisciplinary staff to provide comprehensive pharmacotherapy recommendations, patient/caregiver education, and other medication-related support to children with medical complexity and their families. His current clinical research focuses on optimization of medication therapy management practices in children with polypharmacy, and expansion of pharmacy services to children with medical complexity. Additional scholarship interests include pediatric critical care, sedation and analgesia, psychotropic medication management, and pediatric emergency preparedness.

    Collapse Research 
    Collapse research activities and funding
    R01HS028979     (FEINSTEIN, JAMES A)Apr 1, 2023 - Jan 31, 2028
    Agency for Healthcare Research and Quality
    Optimizing the Clinical Management of Polypharmacy for Children with Medical Complexity
    Role: Co-Investigator
    UPL.520008     (ORTH, LUCAS E)Jun 17, 2019 - Jun 30, 2024
    Colorado Department of Health Care Policy & Financing
    Expansion of Clinical Pharmacy Services in the Children’s Hospital Colorado Special Care Clinic – Comprehensive Medication Management for Children and Youth with Special Healthcare Needs in a Predominately Medicaid-Serviced Population
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Elias ER, Orth LE, Li A, Xu L, Jones SM, Rizzo WB. Cholic acid increases plasma cholesterol in Smith-Lemli-Opitz syndrome: A pilot study. Mol Genet Metab Rep. 2024 Mar; 38:101030. PMID: 38077958.
      View in: PubMed
    2. Orth LE, Feudtner C, Kempe A, Morris MA, Colborn KL, Gritz RM, Linnebur SA, Begum A, Feinstein JA. A coordinated approach for managing polypharmacy among children with medical complexity: rationale and design of the Pediatric Medication Therapy Management (pMTM) randomized controlled trial. BMC Health Serv Res. 2023 Apr 29; 23(1):414. PMID: 37120509.
      View in: PubMed
    3. Feinstein JA, Feudtner C, Kempe A, Orth LE. Anticholinergic Medications and Parent-Reported Anticholinergic Symptoms in Neurologically Impaired Children. J Pain Symptom Manage. 2023 02; 65(2):e109-e114. PMID: 36332769.
      View in: PubMed
    4. Feinstein JA, Orth LE. Making Polypharmacy Safer for Children with Medical Complexity. J Pediatr. 2023 03; 254:4-10. PMID: 36252865.
      View in: PubMed
    5. Lopez JC, Pare JR, Blackmer AB, Orth LE. Treatment-Refractory Dravet Syndrome: Considerations for Novel Medications. J Pediatr Health Care. 2022 Sep-Oct; 36(5):479-488. PMID: 35987555.
      View in: PubMed
    6. Orth LE, Ellingson AS, Azimi SF, Martinez JT, Alhadad AA, Tran BC, Allen CW, Nguyen CT, Duong T, Burkdoll JS, Yoo J, Blackmer AB, Jeffres MN. Allowable room temperature excursions for refrigerated medications: A 20-year review. Am J Health Syst Pharm. 2022 07 22; 79(15):1296-1300. PMID: 35451022.
      View in: PubMed
    7. Marquez C, Thompson R, Feinstein JA, Orth LE. Identifying opportunities for pediatric medication therapy management in children with medical complexity. J Am Pharm Assoc (2003). 2022 Sep-Oct; 62(5):1587-1595.e3. PMID: 35527209.
      View in: PubMed
    8. Feinstein JA, Friedman H, Orth LE, Feudtner C, Kempe A, Samay S, Blackmer AB. Complexity of Medication Regimens for Children With Neurological Impairment. JAMA Netw Open. 2021 08 02; 4(8):e2122818. PMID: 34436607.
      View in: PubMed
    9. Keyes ML, Healy H, Sparger KA, Orth LE, Geha M, Roumiantsev S, Matute JD. Necrotizing Enterocolitis in Neonates With Hyperinsulinemic Hypoglycemia Treated With Diazoxide. Pediatrics. 2021 02; 147(2). PMID: 33483452.
      View in: PubMed
    10. Orth LE, Kelly BJ, Lagasse CA, Collins SW, Ryan MF. Safety and effectiveness of albuterol solutions with and without benzalkonium chloride when administered by continuous nebulization. Am J Health Syst Pharm. 2018 Nov 15; 75(22):1791-1797. PMID: 30282664.
      View in: PubMed
    11. Orth LE, O'Mara KL. Impact of Early Versus Late Diuretic Exposure on Metabolic Bone Disease and Growth in Premature Neonates. J Pediatr Pharmacol Ther. 2018 Jan-Feb; 23(1):26-33. PMID: 29491749.
      View in: PubMed
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