 Heme Oxygenase-1
"Heme Oxygenase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous stress-responsive enzyme that catalyzes the oxidative cleavage of HEME to yield IRON; CARBON MONOXIDE; and BILIVERDIN.
| Descriptor ID |
D051547
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| MeSH Number(s) |
D08.811.682.690.708.410.500
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| Concept/Terms |
Heme Oxygenase-1- Heme Oxygenase-1
- Heme Oxygenase 1
- Oxygenase-1, Heme
- Hemeoxygenase 1
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Below are MeSH descriptors whose meaning is more general than "Heme Oxygenase-1".
Below are MeSH descriptors whose meaning is more specific than "Heme Oxygenase-1".
This graph shows the total number of publications written about "Heme Oxygenase-1" by people in this website by year, and whether "Heme Oxygenase-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 1 | 0 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2007 | 1 | 0 | 1 | | 2008 | 1 | 1 | 2 | | 2009 | 3 | 1 | 4 | | 2010 | 0 | 1 | 1 | | 2011 | 2 | 0 | 2 | | 2012 | 1 | 1 | 2 | | 2013 | 2 | 2 | 4 | | 2014 | 1 | 2 | 3 | | 2015 | 1 | 1 | 2 | | 2016 | 1 | 1 | 2 | | 2018 | 1 | 3 | 4 | | 2019 | 0 | 2 | 2 | | 2021 | 0 | 2 | 2 | | 2024 | 0 | 1 | 1 | | 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heme Oxygenase-1" by people in Profiles.
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Lucero MJ, Lisk C, Cendali F, Swindle D, Setua S, Thangaraju K, Pak DI, O'Boyle Q, Lu S, Tolson R, Zaeske S, Rana N, Khan S, Westover N, DavizonCastillo P, George G, Hassell K, Nuss R, Brinkman N, Gentinetta T, Palmer AF, D'Alessandro A, Buehler PW, Irwin DC. Targeting lung heme iron by aerosol hemopexin adminstration in sickle cell disease pulmonary hypertension. Free Radic Biol Med. 2025 Mar 01; 229:458-473.
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Burmakin M, Gilmour PS, Gram M, Shushakova N, Sandoval RM, Molitoris BA, Larsson TE. Therapeutic a-1-microglobulin ameliorates kidney ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2024 Jul 01; 327(1):F103-F112.
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Schaefer REM, Callahan RC, Atif SM, Orlicky DJ, Cartwright IM, Fontenot AP, Colgan SP, Onyiah JC. Disruption of monocyte-macrophage differentiation and trafficking by a heme analog during active inflammation. Mucosal Immunol. 2022 02; 15(2):244-256.
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Huang H, Dabrazhynetskaya A, Pluznik J, Zheng J, Wu Y, Chizhikov V, Buehler PW, Yamada KM, Dhawan S. Hemin activation abrogates Mycoplasma?hyorhinis replication in chronically infected prostate cancer cells via heme oxygenase-1 induction. FEBS Open Bio. 2021 10; 11(10):2727-2739.
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Goswami DG, Kant R, Ammar DA, Agarwal C, Gomez J, Agarwal R, Saba LM, Fritz KS, Tewari-Singh N. Toxic consequences and oxidative protein carbonylation from chloropicrin exposure in human corneal epithelial cells. Toxicol Lett. 2020 Apr 01; 322:1-11.
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Simenauer A, Assefa B, Rios-Ochoa J, Geraci K, Hybertson B, Gao B, McCord J, Elajaili H, Nozik-Grayck E, Cota-Gomez A. Repression of Nrf2/ARE regulated antioxidant genes and dysregulation of the cellular redox environment by the HIV Transactivator of Transcription. Free Radic Biol Med. 2019 09; 141:244-252.
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Brunt VE, Wiedenfeld-Needham K, Comrada LN, Minson CT. Passive heat therapy protects against endothelial cell hypoxia-reoxygenation via effects of elevations in temperature and circulating factors. J Physiol. 2018 10; 596(20):4831-4845.
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Petersen DR, Orlicky DJ, Roede JR, Shearn CT. Aberrant expression of redox regulatory proteins in patients with concomitant primary Sclerosing cholangitis/inflammatory bowel disease. Exp Mol Pathol. 2018 08; 105(1):32-36.
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Onyiah JC, Schaefer REM, Colgan SP. A Central Role for Heme Oxygenase-1 in the Control of Intestinal Epithelial Chemokine Expression. J Innate Immun. 2018; 10(3):228-238.
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Vallelian F, Schaer CA, Deuel JW, Ingoglia G, Humar R, Buehler PW, Schaer DJ. Revisiting the putative role of heme as a trigger of inflammation. Pharmacol Res Perspect. 2018 04; 6(2):e00392.
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